# Parameters
data_name = "Npas2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root,
overwrite=False)
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Shared Cell types both TF-MoDISco and Homer finds Npas2: #69
| Cell type | Modisco | Homer |
|---|---|---|
| wES;limb;E14.5;D;En |
Significance: 0.00426521 |
Significance: 0.00442536 |
| wES;Fr_lmb;E11.5;D;En |
Significance: 0.0593693 |
Significance: 0.0036918 |
| wES;Hnd_lmb;E11.5;D;En |
Significance: 0.00450526 |
Significance: 0.0391647 |
| wES;FaceP;E14.5;D;En |
Significance: 0.00181243 |
Significance: 0.00457081 |
| preB;A;CL |
Significance: 0.002015 |
Significance: 0.0394218 |
| LRG_INTSTN;8wks;D;En |
Significance: 0.00340725 |
Significance: 0.0254225 |
| B_SPLND;A;GEO |
Significance: 0.00185704 |
Significance: 0.021953 |
| MCRPHG_BMD.UnStmltd;A;GEO |
Significance: 0.0042918 |
Significance: 0.0052886 |
| aB_LSP+a_d_dextran;A;CL |
Significance: 0.00223686 |
Significance: 0.0577882 |
| DC_LPS;6h;A;GEO |
Significance: 0.00254175 |
Significance: 0.050764 |
| ESNPHL_ex-vivo_BlbC;A;CL |
Significance: 0.00320387 |
Significance: 0.047934899999999996 |
| DC_pBMD;A;GEO |
Significance: 0.006975100000000001 |
Significance: 0.0340344 |
| MTR_NRN_MN1;methyl3;D;En |
Significance: 0.00265588 |
Significance: 0.00458051 |
| CN_PHT_RCPTR;A;GEO |
Significance: 0.00351611 |
Significance: 0.0305543 |
| aNonTfh;A;CL |
Significance: 0.00415995 |
Significance: 0.00507246 |
| npES;3rd_Rhmbmr_delA;E8.5;A;GEO |
Significance: 0.0013427 |
Significance: 0.00482494 |
| wES;3rd_Rhmbmr;E8.5;A;GEO |
Significance: 0.00147612 |
Significance: 0.0175117 |
| npES;3rd_Rhmbmr_delC;E8.5;A;GEO |
Significance: 0.00888653 |
Significance: 0.0278062 |
| wES;5th_Rhmbmr;E9.5;A;GEO |
Significance: 0.00244953 |
Significance: 0.0476453 |
| npES;5th_Rhmbmr_delA;E8.5;A;GEO |
Significance: 0.00109477 |
Significance: 0.05069559999999999 |
| CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL |
Significance: 0.00166408 |
Significance: 0.0120556 |
| wES;posterior;1;E8.5;A;GEO |
Significance: 0.0047381 |
Significance: 0.0433135 |
| CD4+CD8-TCR+CD25-Foxp3+;A;CL |
Significance: 0.00465351 |
Significance: 0.0270997 |
| DC_BMD;A;CL |
Significance: 0.00251651 |
Significance: 0.0200055 |
| MCRPHG;A;CL |
Significance: 0.0120418 |
Significance: 0.00109715 |
| DP;A;CL |
Significance: 0.0072623 |
Significance: 0.054239300000000004 |
| DP3a;A;CL |
Significance: 0.00392715 |
Significance: 0.029125 |
| iVIP_NRN;A;GEO |
Significance: 0.00493005 |
Significance: 0.0414306 |
| ISP;A;CL |
Significance: 0.00317684 |
Significance: 0.00525946 |
| ES;ZhBTc4;untreated;A;GEO |
Significance: 0.00154189 |
Significance: 0.013647399999999999 |
| Heart;D;En |
Significance: 0.00135118 |
Significance: 0.051939 |
| npES;ZHBTC4;doxyc;treat;A;GEO |
Significance: 0.00226699 |
Significance: 0.012286700000000001 |
| ES;JM8.N4;Mitosis;A;GEO |
Significance: 0.00831898 |
Significance: 0.0137204 |
| placenta;A;CL |
Significance: 0.00257115 |
Significance: 0.00625604 |
| STMCH;A;CL |
Significance: 0.00734492 |
Significance: 0.029492200000000003 |
| DC;A;En |
Significance: 0.00424708 |
Significance: 0.0587682 |
| ES;ZhBTc4;1;D;GEO |
Significance: 0.00325768 |
Significance: 0.00785267 |
| ES;ZhBTc4;2;D;GEO |
Significance: 0.00288457 |
Significance: 0.011398 |
| ES;D0;D;GEO |
Significance: 0.00681878 |
Significance: 0.0268288 |
| LVR;8wks;D;GEO |
Significance: 0.00269688 |
Significance: 0.018295699999999998 |
| LNG;8wks;D;GEO |
Significance: 0.0016338000000000001 |
Significance: 0.00328634 |
| gamma_delta_TCR;A;CL |
Significance: 0.00528682 |
Significance: 0.00499741 |
| NK;IL2+IL12+;A;CL |
Significance: 0.00251686 |
Significance: 0.0176832 |
| NCR+ILC3+IL23;A;CL |
Significance: 0.00142932 |
Significance: 0.00528766 |
| aB_LPS+IL4_24h;A;CL |
Significance: 0.00305049 |
Significance: 0.050171600000000004 |
| aB_LPS+IL4+Oligomycin_24h;A;CL |
Significance: 0.00132299 |
Significance: 0.0053636000000000005 |
| ES;E14;D;En |
Significance: 0.00602073 |
Significance: 0.0331272 |
| ES;C57BL_6J;R1;D;En |
Significance: 0.0478085 |
Significance: 0.0257497 |
| CH12;med14;A;CL |
Significance: 0.00177726 |
Significance: 0.0182055 |
| wCH12_drug;A;CL |
Significance: 0.00277565 |
Significance: 0.03922030000000001 |
| NIH3T3_FBROBLST;D;En |
Significance: 0.00128008 |
Significance: 0.026069799999999997 |
| KDNY;P0;D;En |
Significance: 0.00105278 |
Significance: 0.0238684 |
| KDNY;8wks;D;En |
Significance: 0.0535457 |
Significance: 0.025976799999999998 |
| NTRPHL;A;GEO |
Significance: 0.00548226 |
Significance: 0.0263024 |
| LVR;8wks;D;En |
Significance: 0.00165977 |
Significance: 0.00534806 |
| wES;LVR;E11.5;D.;En |
Significance: 0.00489407 |
Significance: 0.00308299 |
| LNG;P0;D;En |
Significance: 0.00232818 |
Significance: 0.0450735 |
| ES;129SV_Jae_C57BL6J;A;GEO |
Significance: 0.00403111 |
Significance: 0.0198663 |
| Heart;8wks;D;En |
Significance: 0.00135962 |
Significance: 0.00603152 |
| Heart;P0;D;En |
Significance: 0.00192292 |
Significance: 0.0243051 |
| RTN;A;GEO |
Significance: 0.0023241 |
Significance: 0.0188462 |
| wES;RTN;E11.5;D;En |
Significance: 0.00520103 |
Significance: 0.00565103 |
| ILC3;A;GEO |
Significance: 0.00246377 |
Significance: 0.00512227 |
| naiveT;CD8+;A;GEO |
Significance: 0.00471722 |
Significance: 0.00563593 |
| Muller;P12;D;En |
Significance: 0.0011935000000000001 |
Significance: 0.0358484 |
| Hnd_BRN;P0;D;En |
Significance: 0.003095 |
Significance: 0.042670599999999996 |
| wES;Hnd_BRN;E14.5;D;En |
Significance: 0.00383624 |
Significance: 0.0213062 |
| wES;Md_BRN;E11.5;D;En |
Significance: 0.00293836 |
Significance: 0.00751072 |
| T_MLD;TCR_SV40-I_CD8+;D5;A;GEO |
Significance: 0.00356938 |
Significance: 0.0448281 |
Unique Cell types only TF-MoDISco finds Npas2: #173
| Cell type | Modisco | Homer |
|---|---|---|
| MPP;A;CL |
Significance: 0.013274000000000001 | Absent |
| naiveCD8;A;CL |
Significance: 0.00176281 | Absent |
| memT;CD4+;A;CL |
Significance: 0.00471033 | Absent |
| Th17;CD4+;A;CL |
Significance: 0.00231617 | Absent |
| NK_SPLND;A;CL |
Significance: 0.00275304 | Absent |
| proB;A;CL |
Significance: 0.00176038 | Absent |
| matureB;A;CL |
Significance: 0.0031548 | Absent |
| B1_B;A;CL |
Significance: 0.00162443 | Absent |
| GC_B;A;CL |
Significance: 0.00797362 | Absent |
| plasmaB;A;CL |
Significance: 0.055359000000000005 | Absent |
| aB_LPS;A;CL |
Significance: 0.00368969 | Absent |
| aB_LPS+IL4;A;CL |
Significance: 0.00233603 | Absent |
| aB_LPS+IL21;A;CL |
Significance: 0.00260217 | Absent |
| aB_CD40+IL4;A;CL |
Significance: 0.00368695 | Absent |
| Mast;A;CL |
Significance: 0.00196513 | Absent |
| BSPHL;A;CL |
Significance: 0.00467948 | Absent |
| NTRPHL;A;CL |
Significance: 0.00315195 | Absent |
| Tfh_LCMV;A;CL |
Significance: 0.00354677 | Absent |
| Tfh;A;CL |
Significance: 0.00255052 | Absent |
| aNonTfh_mut;A;CL |
Significance: 0.00270431 | Absent |
| Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL |
Significance: 0.00134355 | Absent |
| Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL |
Significance: 0.00277729 | Absent |
| naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL |
Significance: 0.00583099 | Absent |
| naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL |
Significance: 0.00469112 | Absent |
| largeDPprecrsr;CD4+CD8+CD69-;A;CL |
Significance: 0.00268397 | Absent |
| smallDPprecrsor;CD4+CD8+CD69-;A;CL |
Significance: 0.0516981 | Absent |
| CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL |
Significance: 0.00171909 | Absent |
| CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL |
Significance: 0.00429053 | Absent |
| CD4+CD8intTCR+CD69+CD24+;MHC2defM;A;CL |
Significance: 0.00300934 | Absent |
| CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C |
Significance: 0.00346815 | Absent |
| CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL |
Significance: 0.00249365 | Absent |
| CD4+CD8-TCR+CD25+Foxp3-;A;CL |
Significance: 0.00208366 | Absent |
| CD4+CD8-TCR+CD25+Foxp3+;A;CL |
Significance: 0.00377928 | Absent |
| Erythroblast;A;CL |
Significance: 0.00394609 | Absent |
| DP3b;A;CL |
Significance: 0.00266436 | Absent |
| ES;E14;A;CL |
Significance: 0.00384348 | Absent |
| ES;MEF;A;CL |
Significance: 0.00305406 | Absent |
| SML_INTSTN;A;CL |
Significance: 0.0397895 | Absent |
| LRG_INTSTN;A;CL |
Significance: 0.0014309000000000001 | Absent |
| LNG;A;CL |
Significance: 0.00599094 | Absent |
| Muscle;A;CL |
Significance: 0.036873 | Absent |
| Adipose;A;CL |
Significance: 0.00242117 | Absent |
| testis;A;CL |
Significance: 0.00347749 | Absent |
| SPNL_CHRD;A;CL |
Significance: 0.00373608 | Absent |
| eye-NRL_RTN;A;CL |
Significance: 0.00218198 | Absent |
| NRV;Eye-OPTC;A;CL |
Significance: 0.00207897 | Absent |
| BRN;OLFTRY_BLB;A;CL |
Significance: 0.00215065 | Absent |
| BRN;PTMN;A;CL |
Significance: 0.00345182 | Absent |
| BRN;MDL_OBLNGT;A;CL |
Significance: 0.00323445 | Absent |
| BRN;SNSR_MTR_CRTX;A;CL |
Significance: 0.00416094 | Absent |
| BRN;CRBLM;A;CL |
Significance: 0.00364878 | Absent |
| restingB;A;CL |
Significance: 0.00330304 | Absent |
| aB;CD180;A;CL |
Significance: 0.00232069 | Absent |
| LNG_TRM_HSC;A;CL |
Significance: 0.00312143 | Absent |
| SHRT_TRM_HSC;A;CL |
Significance: 0.0318443 | Absent |
| gamma_delta_TCR_MCR;A;CL |
Significance: 0.0025015999999999997 | Absent |
| gamma_delta_TCR_M-S-;A;CL |
Significance: 0.00185705 | Absent |
| ILC2precrsr;A;CL |
Significance: 0.0310981 | Absent |
| NCR+ILC3;A;CL |
Significance: 0.00155987 | Absent |
| ILC2_Nippo;A;CL |
Significance: 0.00329277 | Absent |
| ILC2;A;CL |
Significance: 0.00151132 | Absent |
| Th2_nippo;A;CL |
Significance: 0.0494955 | Absent |
| CH12_QNTPLE;A;CL |
Significance: 0.00173914 | Absent |
| wCH12;A;CL |
Significance: 0.00202064 | Absent |
| CLP;A;CL |
Significance: 0.00120417 | Absent |
| mem_precrsrT_SPLND;CD8+;A;GEO |
Significance: 0.00354785 | Absent |
| NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO |
Significance: 0.00203408 | Absent |
| ES;J1;A;CL |
Significance: 0.00144206 | Absent |
| ES;E14;A;GEO |
Significance: 0.00659323 | Absent |
| Mammary_GLND;A;GEO |
Significance: 0.0352722 | Absent |
| CRBL_GRNL_Precrsr;A;GEO |
Significance: 0.0015527999999999998 | Absent |
| ILC2+IL33+IL25;A;GEO |
Significance: 0.00589698 | Absent |
| ILC1;A;GEO |
Significance: 0.00142797 | Absent |
| ILC2;A;GEO |
Significance: 0.00322834 | Absent |
| ILC1_AbxGRMFree;A;GEO |
Significance: 0.00250251 | Absent |
| ILC2_AbxGRMFree;A;GEO |
Significance: 0.00680296 | Absent |
| ILC3_AbxGRMFree;A;GEO |
Significance: 0.00230885 | Absent |
| T_LCMV;CD8+;D33;A;GEO |
Significance: 0.00449429 | Absent |
| T_LCMV;CD8+;D35;A;GEO |
Significance: 0.00290033 | Absent |
| TEff_SPLND;CD8+;A;GEO |
Significance: 0.00342505 | Absent |
| TExh_SPLND;CD8+;A;GEO |
Significance: 0.005285 | Absent |
| TSLEC_SPLND;CD8+A;GEO |
Significance: 0.00356863 | Absent |
| naiveT;trnsgncTCR_SV40-I_CD8;A;GEO |
Significance: 0.00533807 | Absent |
| Teff;TCR_SV40-I_CD8+;D7;A;GEO |
Significance: 0.00203472 | Absent |
| cntrl_memT;TCR_SV40-I_CD8+;A;GEO |
Significance: 0.00339843 | Absent |
| T_MLD;TCR_SV40-I_CD8+;D7;A;GEO |
Significance: 0.00441876 | Absent |
| T_MLD;TCR_SV40-I_CD8+;D14;A;GEO |
Significance: 0.00402758 | Absent |
| T_MLD;TCR_SV40-I_CD8+;D21;A;GEO |
Significance: 0.00428617 | Absent |
| T_MLD;TCR_SV40-I_CD8+;D28;A;GEO |
Significance: 0.00450989 | Absent |
| T_MLD;TCR_SV40-I_CD8+;D35;A;GEO |
Significance: 0.00436886 | Absent |
| T_MLD;TCR_SV40-I_CD8+;D60;A;GEO |
Significance: 0.00421899 | Absent |
| memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO |
Significance: 0.00545776 | Absent |
| memT_tmrD_lstr;TCR_SV40-I_CD8+;D35;A;GEO |
Significance: 0.00428877 | Absent |
| memT_tmrD;TCR_SV40-I_CD8+;D7;A;GEO |
Significance: 0.00549208 | Absent |
| memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO |
Significance: 0.00263409 | Absent |
| iNKT;A;GEO |
Significance: 0.00235958 | Absent |
| aB;A;GEO |
Significance: 0.00287533 | Absent |
| prePLSM_B;A;GEO |
Significance: 0.00421415 | Absent |
| preB_BMD;A;GEO |
Significance: 0.0029690999999999997 | Absent |
| B;B220_CD43;A;GEO |
Significance: 0.00383628 | Absent |
| MCRPHG_BMD.LPD_Stmltd;A;GEO |
Significance: 0.0028856 | Absent |
| Erythroid;Ter119+;A;GEO |
Significance: 0.00664889 | Absent |
| AML;AE9a;A;GEO |
Significance: 0.00278771 | Absent |
| DC_LPS;2h;A;GEO |
Significance: 0.00320959 | Absent |
| ROD_PHT_RCPTR;A;GEO |
Significance: 0.005797 | Absent |
| ROD_PHT_RCPTR_RTN;A;GEO |
Significance: 0.00448932 | Absent |
| GCN_PHT_RCPTR;A;GEO |
Significance: 0.00433322 | Absent |
| BL_CN_PHT_RCPTR;A;GEO |
Significance: 0.0020474 | Absent |
| npES;5th_Rhmbmr_delC;E8.5;A;GEO |
Significance: 0.00919174 | Absent |
| wES;5th_Rhmbmr;E8.5;A;GEO |
Significance: 0.00148337 | Absent |
| wES;posterior;1;E9.5;A;GEO |
Significance: 0.00308343 | Absent |
| wES;posterior;2;E9.5;A;GEO |
Significance: 0.00205325 | Absent |
| npES;posterior_delA;E8.5;A;GEO |
Significance: 0.00431597 | Absent |
| npES;posterior_delC;E8.5;A;GEO |
Significance: 0.00339012 | Absent |
| BCK_SKN;A;GEO |
Significance: 0.00280909 | Absent |
| wES.CRNL_NRL_CRST;E10.5;A;GEO |
Significance: 0.00686386 | Absent |
| NPC;F129;A;GEO |
Significance: 0.00481909 | Absent |
| ePyramidal_NRN;A;GEO |
Significance: 0.0594452 | Absent |
| iPV_NRN;A;GEO |
Significance: 0.000710288 | Absent |
| G_NRN_P;A;GEO |
Significance: 0.00284463 | Absent |
| wES;GRM;E16.5;A;GEO |
Significance: 0.00789368 | Absent |
| ThMS_MEC;Aire++;A;GEO |
Significance: 0.0589307 | Absent |
| Melanotrope;A;GEO |
Significance: 0.0107571 | Absent |
| npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO |
Significance: 0.00187404 | Absent |
| ES;JM8.N4;Asynch;A;GEO |
Significance: 0.0039343 | Absent |
| Mammary_BptfKO;A;GEO |
Significance: 0.00249238 | Absent |
| pMeg;A;En |
Significance: 0.00410743 | Absent |
| EPP;A;En |
Significance: 0.00595067 | Absent |
| MegEP;A;CL |
Significance: 0.00573363 | Absent |
| pErythroblast;A;En |
Significance: 0.00622255 | Absent |
| MegP;A;En |
Significance: 0.00418178 | Absent |
| pCMP;A;CL |
Significance: 0.00713888 | Absent |
| DC_LPS;4h;A;En |
Significance: 0.0464186 | Absent |
| NIH3T3_FBROBLST;D;GEO |
Significance: 0.00201018 | Absent |
| 3134_mammaryADNCRCNM;D;GE |
Significance: 0.0312607 | Absent |
| T_SPLND_blstCLTRD;CD4+;D;GEO |
Significance: 0.00196599 | Absent |
| naiveT_SPLND;CD4+;D;GEO |
Significance: 0.00216444 | Absent |
| apCD4Eff;D;GEO |
Significance: 0.00353966 | Absent |
| 416B_MP;CD34+;D;GEO |
Significance: 0.00186313 | Absent |
| WHL_BRN;8wks;D;GEO |
Significance: 0.0021885000000000003 | Absent |
| ES;129S1_SVImJ_CJ7;D;En |
Significance: 0.00260192 | Absent |
| FBRBLST;8wks;D;En |
Significance: 0.00259418 | Absent |
| 3T3-L1;FBRBLST;D;En |
Significance: 0.00293824 | Absent |
| LVR;P0;D;En |
Significance: 0.00234501 | Absent |
| LNG;8wks;D;En |
Significance: 0.0554796 | Absent |
| Adipose;D;En |
Significance: 0.00396237 | Absent |
| RTN;D1;D;En |
Significance: 0.00135103 | Absent |
| CRBLM;D;En |
Significance: 0.00911626 | Absent |
| abTreg;CD4+_CD25+;8wks;D;En |
Significance: 0.00291962 | Absent |
| EP;c-kit+CD71+Ter119+;D;En |
Significance: 0.00706481 | Absent |
| 416B_MP;CD34+;D;En |
Significance: 0.00529281 | Absent |
| wES;MSDRM;E11.5;D;En |
Significance: 0.00243766 | Absent |
| wES.Fr_BRN;E14.4;D;En |
Significance: 0.00228643 | Absent |
| wES;Hnd_BRN;E11.5;D;En |
Significance: 0.00307624 | Absent |
| wES;Md_BRN;E14.4;D;En |
Significance: 0.00275099 | Absent |
| Md_BRN;D;En |
Significance: 0.00241688 | Absent |
| WHL_BRN;8wks;D;En |
Significance: 0.052477800000000005 | Absent |
| wES;Telenchephalon;D;En |
Significance: 0.00356018 | Absent |
| wES;limb;E11.5;D;En |
Significance: 0.00370044 | Absent |
| wES;FaceP;E11.5;D;En |
Significance: 0.00248928 | Absent |
| wES;NRL_Tube;E11.5;D;En |
Significance: 0.00279973 | Absent |
| STMCH;P0;D;En |
Significance: 0.0471761 | Absent |
| SKLTL_Muscle;8wks;D;En |
Significance: 0.00341109 | Absent |
| Spleen;8wks;D;En |
Significance: 0.00266652 | Absent |
| 3134_mammaryADNCRCNM;D;En |
Significance: 0.00181784 | Absent |
| 416B;HMTP_SPNSN;CD34+;D;En |
Significance: 0.00230037 | Absent |
| AML;D;En |
Significance: 0.00277265 | Absent |
| CH12.LX;D;En |
Significance: 0.00302433 | Absent |
| MEF.GATA-1-ER;D;En |
Significance: 0.00814883 | Absent |
| MEL;D;En |
Significance: 0.00529228 | Absent |
| MEL_Znc_di-cl;24h;D;En |
Significance: 0.00493455 | Absent |
| NIH3T3;D;En |
Significance: 0.00441489 | Absent |
| 3T3-L1;D;En |
Significance: 0.00764432 | Absent |
Unique Cell types only Homer finds Npas2: #7
| Cell type | Modisco | Homer |
|---|---|---|
| ES;F1216;A;GEO | Absent |
Significance: 0.048338900000000004 |
| NPC;Ch13;A;GEO | Absent |
Significance: 0.00532264 |
| A20;B-lymphoma;D;En | Absent |
Significance: 0.0141507 |
| apThEff;CD4+;8wks;D;En. | Absent |
Significance: 0.0535021 |
| Treg;CD4+_CD25+;D;GEO | Absent |
Significance: 0.0192164 |
| ENDRM_ESD;A;GEO | Absent |
Significance: 0.00494533 |
| Fr_BRN;P0;D;En | Absent |
Significance: 0.04147580000000001 |
