In [1]:
# Parameters
data_name = "ES;D0;D;GEO"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_200-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_200-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 19:26:41,490 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeEmbryonic day 0 (stem cell, ES-CJ7)
    Cell GroupES cells and embryonic tissues
    Experiment NameDHS
    Experiment GroupGEO
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep11862321239268.1646115819715207861250.1795109745710.0948471445000.4071
    Modelling Metadata
    MetricValue
    auPRC0.6019
    Calibrated Recall at 50% FDR0.285
    Number of Positive Examples in Test Data83919
    Number of Negative Examples in Test Data7986932
    Imbalance Ratio in Test Data0.0104
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #25
Pattern NameTF Name(s)Modisco
metacluster_0/pattern_0 # seqlets: 3275 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_0/pattern_1 # seqlets: 3034 SequenceContrib ScoresHyp_Contrib Scores
Sp3, Sp1, Sp2, Sp4, Klf3, Zbtb17, Klf7, Egr1, Klf8, E2f4,

Klf12, Klf6, Egr2, E2f1, Klf4, Klf1, Klf5, Zfp281, Sp5, Maz, Klf15,

Wt1, Sall4, Egr3, Zfp740, Zbtb1
metacluster_0/pattern_2 # seqlets: 947 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_0/pattern_3 # seqlets: 909 SequenceContrib ScoresHyp_Contrib Scores
Pou5f1, Nanog, Pou2f2, Sox2, Pou2f1
metacluster_0/pattern_4 # seqlets: 858 SequenceContrib ScoresHyp_Contrib Scores
Gabpa, Elf1, Fli1, Elk1, Elk4, Erg, Ets1, Elk3, Fev, Elf5,

Etv5, Etv1, Elf2, Etv4, Elf4, Etv6, Ehf, Etv3, XP_911724.4, Etv2, Spi1,

Elf3, Spdef, Stat3, Stat6
metacluster_0/pattern_5 # seqlets: 850 SequenceContrib ScoresHyp_Contrib Scores
Zfx, Mbd2, Mxi1, Usf2, Rfx1
metacluster_0/pattern_6 # seqlets: 749 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_0/pattern_7 # seqlets: 701 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_8 # seqlets: 668 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfeb, Tfec, Srebf1, Bhlhe40, Tfe3, Mitf, Arntl, Mlx, Clock,

Atf1, Srebf2, Arnt, Npas2, Creb1, Bhlhe41, Tcfl5, Creb3l2, Atf7, Xbp1, Atf2,

Crem, Jdp2, Creb5, Dbp, Max, Myc, Mlxip, Hlf, Rxrb, Mycn
metacluster_0/pattern_9 # seqlets: 642 SequenceContrib ScoresHyp_Contrib Scores
Lef1, Sox30, Sox3, Sox4, Sry, Sox6, Sox12, Sox17, Sox14, Sox21,

Sox11, Sox7, Sox8, Sox18, Sox5
metacluster_0/pattern_10 # seqlets: 530 SequenceContrib ScoresHyp_Contrib Scores
Esrrb, Rxrg, Rxra, Rara, Esrra, Rarg, Nr5a2, Esrrg, Nr5a1, Nr2f6,

Nr2c2, Pparg, Ppara, Nr1h3, Nr4a2, Nr2f1, Hnf4a, Nkx2-9
metacluster_0/pattern_11 # seqlets: 442 SequenceContrib ScoresHyp_Contrib Scores
Tead4, Tead2, Tead1
metacluster_0/pattern_12 # seqlets: 314 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_13 # seqlets: 302 SequenceContrib ScoresHyp_Contrib Scores
Zic2, Zic3
metacluster_0/pattern_14 # seqlets: 264 SequenceContrib ScoresHyp_Contrib Scores
Rfx2, Rfx3, Rfx4, Rfx7, Rfx6
metacluster_0/pattern_15 # seqlets: 244 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Zfp42
metacluster_0/pattern_16 # seqlets: 187 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_0/pattern_17 # seqlets: 180 SequenceContrib ScoresHyp_Contrib Scores
Tcfcp2l1
metacluster_0/pattern_18 # seqlets: 167 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_0/pattern_19 # seqlets: 114 SequenceContrib ScoresHyp_Contrib Scores
Bach2, Nfe2l2, Nfe2, Bach1, Mafk, Mafg, Mafa, Mafb, Maff, Maf,

Jun, Atf3, Fosl2, Fosb, Junb, Fosl1, Jund, Batf, Fos
metacluster_0/pattern_20 # seqlets: 77 SequenceContrib ScoresHyp_Contrib Scores
Rest
metacluster_0/pattern_21 # seqlets: 75 SequenceContrib ScoresHyp_Contrib Scores
Six2, Six4, Six1
metacluster_0/pattern_22 # seqlets: 62 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_23 # seqlets: 42 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_24 # seqlets: 41 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #174
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_05.288580000000001e-10
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_01.80805e-06
metacluster_0/pattern_50.00529132
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_11.0739100000000001e-07
metacluster_0/pattern_50.00058032
metacluster_0/pattern_70.00214788
metacluster_0/pattern_150.00605821
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000215446
metacluster_0/pattern_50.00123211
metacluster_0/pattern_70.00166268
metacluster_0/pattern_150.00614799
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_11.8816099999999998e-05
metacluster_0/pattern_53.1455e-05
metacluster_0/pattern_70.000273486
metacluster_0/pattern_150.000757357
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000695283
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_17.80109e-05
metacluster_0/pattern_50.00378977
metacluster_0/pattern_70.05379249999999999
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000215446
metacluster_0/pattern_50.0104384
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000219237
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0116934
metacluster_0/pattern_50.0396621
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000269153
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000269153
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_10.029666700000000004
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000379071
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0122027
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00124029
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00198708
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.032570299999999996
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00198708
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00297286
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00297286
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00709016
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00796132
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00905325
metacluster_0/pattern_50.0288611
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0182037
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.022381
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_10.023033900000000003
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0416069
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_21.96274e-13
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_21.95185e-10
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_21.5824100000000001e-09
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_22.06595e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_27.016110000000001e-06
Pou5f1
Pattern NameModiscoSignificance
metacluster_0/pattern_34.12462e-05
metacluster_0/pattern_90.00171742
Nanog
Pattern NameModiscoSignificance
metacluster_0/pattern_33.48805e-06
metacluster_0/pattern_94.23193e-08
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00784362
Sox2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000162212
metacluster_0/pattern_90.00195153
Pou2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0574842
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00325931
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_47.271569999999999e-09
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
metacluster_0/pattern_50.0119262
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00325931
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00406407
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00325931
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00251163
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00880636
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00257505
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00339462
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00679439
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00348323
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00434608
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00413213
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00413213
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0111561
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.015373300000000001
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.015653999999999998
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0215496
Stat3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.05575069999999999
Stat6
Pattern NameModiscoSignificance
metacluster_0/pattern_40.05998150000000001
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0119262
metacluster_0/pattern_70.00124725
metacluster_0/pattern_150.0121156
metacluster_0/pattern_180.0159074
Mbd2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0119262
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.015542199999999999
metacluster_0/pattern_70.0330761
metacluster_0/pattern_150.046047000000000005
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0220433
metacluster_0/pattern_70.0177425
metacluster_0/pattern_80.00339472
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.050006699999999994
metacluster_0/pattern_70.05379249999999999
metacluster_0/pattern_148.76083e-07
metacluster_0/pattern_150.00583981
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_62.0266700000000002e-08
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00139936
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00139936
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00271337
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.013055100000000002
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00680541
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00271337
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00194482
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0080701
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0266815
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0008622689999999999
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00168982
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00183604
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0435149
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00681878
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0441725
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_80.010658200000000001
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0121
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.031227800000000003
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_80.012857200000000001
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.017288099999999997
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.030271499999999996
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0234803
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0396858
metacluster_0/pattern_190.0381523
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0391824
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_80.045879199999999995
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0462879
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_80.047908
Mlxip
Pattern NameModiscoSignificance
metacluster_0/pattern_80.048726
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0491224
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0538286
metacluster_0/pattern_100.0127539
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0572265
Lef1
Pattern NameModiscoSignificance
metacluster_0/pattern_97.47914e-05
Sox30
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00048619300000000005
Sox3
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0350765
Sox4
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0237088
Sry
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00655831
Sox6
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0119045
Sox12
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0055819
Sox17
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00799584
Sox14
Pattern NameModiscoSignificance
metacluster_0/pattern_90.014733600000000001
Sox21
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0148077
Sox11
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0175708
Sox7
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0185319
Sox8
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0237088
Sox18
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0237088
Sox5
Pattern NameModiscoSignificance
metacluster_0/pattern_90.044869099999999995
Esrrb
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0008080110000000001
Rxrg
Pattern NameModiscoSignificance
metacluster_0/pattern_106.14933e-07
Rxra
Pattern NameModiscoSignificance
metacluster_0/pattern_100.014266399999999999
Rara
Pattern NameModiscoSignificance
metacluster_0/pattern_101.21289e-06
Esrra
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00323272
Rarg
Pattern NameModiscoSignificance
metacluster_0/pattern_102.6613099999999997e-06
Nr5a2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000135945
Esrrg
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0006088269999999999
Nr5a1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000149005
Nr2f6
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0123557
Nr2c2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0154725
Pparg
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0350154
Ppara
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0197017
Nr1h3
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0296502
Nr4a2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0350154
Nr2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0440455
Hnf4a
Pattern NameModiscoSignificance
metacluster_0/pattern_100.048276
Nkx2-9
Pattern NameModiscoSignificance
metacluster_0/pattern_100.048329500000000004
Tead4
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000541885
Tead2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00407969
Tead1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00726116
Zic2
Pattern NameModiscoSignificance
metacluster_0/pattern_134.17321e-06
Zic3
Pattern NameModiscoSignificance
metacluster_0/pattern_133.82304e-05
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_144.76922e-07
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_140.019728
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_148.475540000000001e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00896681
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_140.016622900000000003
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_151.92472e-06
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_153.71923e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_150.00525724
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_165.89601e-20
metacluster_0/pattern_243.4988799999999996e-07
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_161.69484e-19
metacluster_0/pattern_247.11669e-07
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_166.01784e-15
metacluster_0/pattern_247.11669e-07
Tcfcp2l1
Pattern NameModiscoSignificance
metacluster_0/pattern_175.81039e-06
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_180.000267151
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_197.26214e-07
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_192.53938e-05
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_192.02305e-05
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_192.79125e-05
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00010189799999999999
Mafg
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000320133
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000320133
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_190.0006037880000000001
Maff
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000336753
Maf
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000851938
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000999571
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00163841
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_190.0049858
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00360568
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00424501
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00473039
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_190.046863699999999994
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00855475
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00934384
Rest
Pattern NameModiscoSignificance
metacluster_0/pattern_204.45929e-15
Six2
Pattern NameModiscoSignificance
metacluster_0/pattern_213.25571e-06
Six4
Pattern NameModiscoSignificance
metacluster_0/pattern_212.95108e-05
Six1
Pattern NameModiscoSignificance
metacluster_0/pattern_212.95108e-05
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #70
TF NameModiscoHomer
Rara
Pattern NameModiscoSignificance
metacluster_0/pattern_101.21289e-06
Pattern NameHomerSignificance
motif14.motif0.00766523
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_21.5824100000000001e-09
Pattern NameHomerSignificance
motif3.motif4.83794e-06
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00271337
Pattern NameHomerSignificance
motif9.motif0.008097199999999999
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0391824
Pattern NameHomerSignificance
motif9.motif0.010106299999999999
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00139936
Pattern NameHomerSignificance
motif9.motif0.0028373
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_161.69484e-19
metacluster_0/pattern_247.11669e-07
Pattern NameHomerSignificance
motif7.motif0.00041062199999999997
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0080701
Pattern NameHomerSignificance
motif9.motif0.0268288
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00271337
Pattern NameHomerSignificance
motif9.motif0.00925929
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_11.0739100000000001e-07
metacluster_0/pattern_50.00058032
metacluster_0/pattern_70.00214788
metacluster_0/pattern_150.00605821
Pattern NameHomerSignificance
motif2.motif0.000469715
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_22.06595e-06
Pattern NameHomerSignificance
motif3.motif0.0007110069999999999
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0572265
Pattern NameHomerSignificance
motif9.motif0.038901099999999994
Rxrg
Pattern NameModiscoSignificance
metacluster_0/pattern_106.14933e-07
Pattern NameHomerSignificance
motif14.motif0.00838183
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_05.288580000000001e-10
Pattern NameHomerSignificance
motif1.motif9.30117e-06
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_62.0266700000000002e-08
Pattern NameHomerSignificance
motif4.motif9.9514e-08
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00183604
Pattern NameHomerSignificance
motif9.motif0.0552725
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.017288099999999997
Pattern NameHomerSignificance
motif9.motif0.0269653
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0396858
metacluster_0/pattern_190.0381523
Pattern NameHomerSignificance
motif9.motif0.0226523
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_21.95185e-10
Pattern NameHomerSignificance
motif3.motif4.83794e-06
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00168982
Pattern NameHomerSignificance
motif9.motif0.00476752
Sox2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000162212
metacluster_0/pattern_90.00195153
Pattern NameHomerSignificance
motif6.motif1.29711e-06
motif13.motif0.058126800000000006
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0266815
Pattern NameHomerSignificance
motif9.motif0.0296448
Nr5a2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000135945
Pattern NameHomerSignificance
motif14.motif0.00196337
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_01.80805e-06
metacluster_0/pattern_50.00529132
Pattern NameHomerSignificance
motif1.motif0.000229447
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00784362
Pattern NameHomerSignificance
motif6.motif0.0169815
Nanog
Pattern NameModiscoSignificance
metacluster_0/pattern_33.48805e-06
metacluster_0/pattern_94.23193e-08
Pattern NameHomerSignificance
motif6.motif2.10331e-07
motif13.motif0.058126800000000006
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0121
Pattern NameHomerSignificance
motif9.motif0.0501777
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000269153
Pattern NameHomerSignificance
motif2.motif0.00026509
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000269153
Pattern NameHomerSignificance
motif2.motif0.000756521
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_165.89601e-20
metacluster_0/pattern_243.4988799999999996e-07
Pattern NameHomerSignificance
motif7.motif0.0007286080000000001
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_17.80109e-05
metacluster_0/pattern_50.00378977
metacluster_0/pattern_70.05379249999999999
Pattern NameHomerSignificance
motif2.motif0.000187325
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.013055100000000002
Pattern NameHomerSignificance
motif9.motif0.0128737
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.032570299999999996
Pattern NameHomerSignificance
motif2.motif0.00870789
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00198708
Pattern NameHomerSignificance
motif2.motif0.014806399999999999
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00680541
Pattern NameHomerSignificance
motif9.motif0.012829399999999998
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0220433
metacluster_0/pattern_70.0177425
metacluster_0/pattern_80.00339472
Pattern NameHomerSignificance
motif9.motif0.019254
Pou5f1
Pattern NameModiscoSignificance
metacluster_0/pattern_34.12462e-05
metacluster_0/pattern_90.00171742
Pattern NameHomerSignificance
motif6.motif2.53827e-06
motif13.motif0.0585804
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00681878
Pattern NameHomerSignificance
motif9.motif0.0268288
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_21.96274e-13
Pattern NameHomerSignificance
motif3.motif1.41316e-07
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0441725
Pattern NameHomerSignificance
motif9.motif0.0171939
Esrrg
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0006088269999999999
Pattern NameHomerSignificance
motif14.motif0.00044510400000000004
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00198708
Pattern NameHomerSignificance
motif2.motif0.00405421
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_10.029666700000000004
Pattern NameHomerSignificance
motif2.motif0.00356772
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00194482
Pattern NameHomerSignificance
motif9.motif0.00481025
Rarg
Pattern NameModiscoSignificance
metacluster_0/pattern_102.6613099999999997e-06
Pattern NameHomerSignificance
motif9.motif0.043118300000000005
motif14.motif0.00485338
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0538286
metacluster_0/pattern_100.0127539
Pattern NameHomerSignificance
motif9.motif0.045085900000000005
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_80.012857200000000001
Pattern NameHomerSignificance
motif9.motif0.027751099999999997
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_27.016110000000001e-06
Pattern NameHomerSignificance
motif3.motif0.000326997
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_80.010658200000000001
Pattern NameHomerSignificance
motif9.motif0.0171939
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0008622689999999999
Pattern NameHomerSignificance
motif9.motif0.00329133
Rxra
Pattern NameModiscoSignificance
metacluster_0/pattern_100.014266399999999999
Pattern NameHomerSignificance
motif14.motif0.00899205
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0116934
metacluster_0/pattern_50.0396621
Pattern NameHomerSignificance
motif2.motif0.00820859
Rest
Pattern NameModiscoSignificance
metacluster_0/pattern_204.45929e-15
Pattern NameHomerSignificance
motif19.motif0.000584255
motif25.motif0.0218546
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0234803
Pattern NameHomerSignificance
motif9.motif0.010065600000000001
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0122027
Pattern NameHomerSignificance
motif2.motif0.0433027
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_11.8816099999999998e-05
metacluster_0/pattern_53.1455e-05
metacluster_0/pattern_70.000273486
metacluster_0/pattern_150.000757357
Pattern NameHomerSignificance
motif2.motif0.000509064
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.030271499999999996
Pattern NameHomerSignificance
motif9.motif0.055827199999999993
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00163841
Pattern NameHomerSignificance
motif9.motif0.027751099999999997
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000695283
Pattern NameHomerSignificance
motif2.motif0.037880800000000006
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0435149
Pattern NameHomerSignificance
motif9.motif0.0459953
Nr4a2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0350154
Pattern NameHomerSignificance
motif14.motif0.024712599999999998
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000219237
Pattern NameHomerSignificance
motif2.motif0.000208038
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000215446
metacluster_0/pattern_50.00123211
metacluster_0/pattern_70.00166268
metacluster_0/pattern_150.00614799
Pattern NameHomerSignificance
motif2.motif0.0226965
Nr5a1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000149005
Pattern NameHomerSignificance
motif14.motif0.00485338
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_166.01784e-15
metacluster_0/pattern_247.11669e-07
Pattern NameHomerSignificance
motif7.motif0.00104858
Nr2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0440455
Pattern NameHomerSignificance
motif14.motif0.04648719999999999
Esrrb
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0008080110000000001
Pattern NameHomerSignificance
motif14.motif0.04648719999999999
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.031227800000000003
Pattern NameHomerSignificance
motif9.motif0.0530457
Esrra
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00323272
Pattern NameHomerSignificance
motif14.motif0.0283921
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000379071
Pattern NameHomerSignificance
motif2.motif0.00111978
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00139936
Pattern NameHomerSignificance
motif9.motif0.0268288
Unique TF-MoDISco TFs: #104
TF NameModiscoHomer
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00339462
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.015542199999999999
metacluster_0/pattern_70.0330761
metacluster_0/pattern_150.046047000000000005
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_10.023033900000000003
Absent
Sox12
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0055819
Absent
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0416069
Absent
Maff
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000336753
Absent
Sox30
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00048619300000000005
Absent
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0215496
Absent
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Absent
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_151.92472e-06
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00796132
Absent
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000999571
Absent
Sox5
Pattern NameModiscoSignificance
metacluster_0/pattern_90.044869099999999995
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00010189799999999999
Absent
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.015653999999999998
Absent
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Absent
Pparg
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0350154
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00124029
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_192.02305e-05
Absent
Sox7
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0185319
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_153.71923e-06
Absent
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00413213
Absent
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00855475
Absent
Lef1
Pattern NameModiscoSignificance
metacluster_0/pattern_97.47914e-05
Absent
Zic2
Pattern NameModiscoSignificance
metacluster_0/pattern_134.17321e-06
Absent
Sox14
Pattern NameModiscoSignificance
metacluster_0/pattern_90.014733600000000001
Absent
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00325931
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00896681
Absent
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00424501
Absent
Six1
Pattern NameModiscoSignificance
metacluster_0/pattern_212.95108e-05
Absent
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00880636
Absent
Sox18
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0237088
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_192.53938e-05
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000320133
Absent
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00325931
Absent
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00709016
Absent
Nr1h3
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0296502
Absent
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00934384
Absent
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_80.047908
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_190.0006037880000000001
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00905325
metacluster_0/pattern_50.0288611
Absent
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
metacluster_0/pattern_50.0119262
Absent
Stat3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.05575069999999999
Absent
Nkx2-9
Pattern NameModiscoSignificance
metacluster_0/pattern_100.048329500000000004
Absent
Nr2c2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0154725
Absent
Sox21
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0148077
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00297286
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0491224
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0182037
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_140.019728
Absent
Tead2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00407969
Absent
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.015373300000000001
Absent
Stat6
Pattern NameModiscoSignificance
metacluster_0/pattern_40.05998150000000001
Absent
Maf
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000851938
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_190.0049858
Absent
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00679439
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_192.79125e-05
Absent
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Absent
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0111561
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_0/pattern_80.048726
Absent
Sox3
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0350765
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0119262
metacluster_0/pattern_70.00124725
metacluster_0/pattern_150.0121156
metacluster_0/pattern_180.0159074
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_140.016622900000000003
Absent
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00406407
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_150.00525724
Absent
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00348323
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_197.26214e-07
Absent
Ppara
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0197017
Absent
Sox6
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0119045
Absent
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00257505
Absent
Zic3
Pattern NameModiscoSignificance
metacluster_0/pattern_133.82304e-05
Absent
Six4
Pattern NameModiscoSignificance
metacluster_0/pattern_212.95108e-05
Absent
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_190.046863699999999994
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000215446
metacluster_0/pattern_50.0104384
Absent
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00251163
Absent
Hnf4a
Pattern NameModiscoSignificance
metacluster_0/pattern_100.048276
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00360568
Absent
Sox11
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0175708
Absent
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00325931
Absent
Sox8
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0237088
Absent
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00434608
Absent
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_47.271569999999999e-09
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00297286
Absent
Tcfcp2l1
Pattern NameModiscoSignificance
metacluster_0/pattern_175.81039e-06
Absent
Tead4
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000541885
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.022381
Absent
Sry
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00655831
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_80.045879199999999995
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_190.00473039
Absent
Pou2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0574842
Absent
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0035544000000000005
Absent
Tead1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00726116
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_148.475540000000001e-05
Absent
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_40.00413213
Absent
Nr2f6
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0123557
Absent
Sox4
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0237088
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000320133
Absent
Mbd2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0119262
Absent
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0462879
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_180.000267151
Absent
Sox17
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00799584
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_144.76922e-07
Absent
Six2
Pattern NameModiscoSignificance
metacluster_0/pattern_213.25571e-06
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.050006699999999994
metacluster_0/pattern_70.05379249999999999
metacluster_0/pattern_148.76083e-07
metacluster_0/pattern_150.00583981
Absent
Unique Homer TFs: #1
TF NameModiscoHomer
Sox13Absent
Pattern NameHomerSignificance
motif13.motif0.058126800000000006