In [1]:
# Parameters
data_name = "restingB;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_73-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_73-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:56:50,799 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typerestingB
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1451293111713.02535448049944149930.081147425840.0871172184150.3162
    Modelling Metadata
    MetricValue
    auPRC0.7228
    Calibrated Recall at 50% FDR0.16
    Number of Positive Examples in Test Data39260
    Number of Negative Examples in Test Data8031591
    Imbalance Ratio in Test Data0.0049
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #18
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 4737 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 3920 SequenceContrib ScoresHyp_Contrib Scores
Ets1, Etv6, Spi1, Etv2, Erg, Spib, Gabpa, Elk1, Fli1, Etv4,

Etv3, XP_911724.4, Elk4, Spic, Elk3, Etv5, Elf1, Etv1, Elf4, Irf4, Irf8,

Elf2, Ehf, Elf3, Elf5, Spdef, Fev, Prdm1, Irf2, Irf1, Irf3
metacluster_1/pattern_2 # seqlets: 3775 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Klf4, Klf1,

Klf8, Klf12, Egr1, Zbtb17, Egr2, E2f1, Sp5, Klf5, Zfp281, Zfx, Zfp740
metacluster_1/pattern_3 # seqlets: 2048 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_4 # seqlets: 1699 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1530 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Jdp2, Atf2, Atf7, Creb5, Atf1, Crem, Jun, Atf3, Gmeb2,

Fosl2, Junb
metacluster_1/pattern_6 # seqlets: 1217 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Rfx1, Zfp42
metacluster_1/pattern_7 # seqlets: 1076 SequenceContrib ScoresHyp_Contrib Scores
Stat2, Irf7, Stat1, Zscan10, Irf9
metacluster_1/pattern_8 # seqlets: 998 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_9 # seqlets: 782 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Usf2, Tfec, Arntl, Tfeb, Mitf, Bhlhe40, Srebf1, Tfe3, Clock,

Mlx, Arnt, Npas2, Srebf2, Tcfl5, Creb3l2, Bhlhe41, Xbp1, Hlf, Mlxip, Dbp,

Max, Arnt2
metacluster_1/pattern_10 # seqlets: 458 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_1/pattern_11 # seqlets: 334 SequenceContrib ScoresHyp_Contrib Scores
Wt1, Maz, Klf15, Sall4, Mxi1, Tfap2c
metacluster_1/pattern_12 # seqlets: 241 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_13 # seqlets: 140 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_14 # seqlets: 125 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_15 # seqlets: 109 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_16 # seqlets: 107 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2c, Mef2a
metacluster_1/pattern_17 # seqlets: 41 SequenceContrib ScoresHyp_Contrib Scores
Nfib, Nfia, Zfp322a, Nfic
Click here for Motifs by TF-MoDISco: #132
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_02.4583e-13
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_04.519419999999999e-08
metacluster_1/pattern_110.055947500000000004
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_13.81685e-05
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0007779989999999999
metacluster_1/pattern_70.0548303
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000729038
metacluster_1/pattern_70.0012075
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_13.81685e-05
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_13.82528e-05
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_13.81685e-05
metacluster_1/pattern_72.95968e-08
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0037626999999999995
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00021448900000000003
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00040407
metacluster_1/pattern_110.05001919999999999
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019330200000000001
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_15.3788999999999996e-05
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_18.16204e-05
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000137048
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0006106169999999999
metacluster_1/pattern_70.018606400000000002
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019330200000000001
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000109175
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00012223100000000002
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000236309
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019330200000000001
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00021223900000000003
metacluster_1/pattern_70.0286895
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00021223900000000003
metacluster_1/pattern_78.50796e-15
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0126131
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00110966
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00393792
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.017058900000000002
metacluster_1/pattern_70.022825400000000003
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0049218000000000005
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00467782
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00691944
metacluster_1/pattern_70.00932996
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00768817
metacluster_1/pattern_70.022825400000000003
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013165799999999998
metacluster_1/pattern_79.28323e-06
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.014472399999999998
metacluster_1/pattern_70.0006076380000000001
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00160998
metacluster_1/pattern_110.012136599999999999
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_23.50889e-06
metacluster_1/pattern_30.0288801
metacluster_1/pattern_60.000235913
metacluster_1/pattern_111.1452900000000001e-10
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_27.964069999999998e-06
metacluster_1/pattern_60.00771159
metacluster_1/pattern_112.60324e-08
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.71368e-05
metacluster_1/pattern_112.93567e-07
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000537819
metacluster_1/pattern_60.00771159
metacluster_1/pattern_110.00282741
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0005097480000000001
metacluster_1/pattern_110.00907386
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000537819
metacluster_1/pattern_112.0756799999999998e-05
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0007614610000000001
metacluster_1/pattern_110.0007551389999999999
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0178123
metacluster_1/pattern_110.000452472
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0178123
metacluster_1/pattern_110.0255448
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00132864
metacluster_1/pattern_110.000801092
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0165226
metacluster_1/pattern_110.00040052400000000003
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0574145
metacluster_1/pattern_110.00661846
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00709576
metacluster_1/pattern_110.000572312
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0574145
metacluster_1/pattern_60.05381609999999999
metacluster_1/pattern_110.0267967
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0131434
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0205423
metacluster_1/pattern_118.16315e-06
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0251145
metacluster_1/pattern_110.00018481700000000002
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0272614
metacluster_1/pattern_110.00265236
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0316149
metacluster_1/pattern_30.037155
metacluster_1/pattern_60.00771159
metacluster_1/pattern_110.0153803
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0574145
metacluster_1/pattern_110.00300457
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.5933400000000002e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_44.96156e-15
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_43.5931300000000005e-12
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_44.32823e-11
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_44.82279e-07
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_42.40522e-06
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00334506
metacluster_1/pattern_90.0589352
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00434427
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00836844
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00385736
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00225013
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.008317299999999998
metacluster_1/pattern_90.00921443
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_50.035407
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_50.034642
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0179171
Gmeb2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0447726
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.047954699999999996
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0563428
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.06308e-06
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.06308e-06
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00924289
metacluster_1/pattern_132.2254499999999999e-13
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0116559
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00550988
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00705912
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00774309
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0087715
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_70.018453599999999997
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_81.11357e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_81.7728800000000003e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_81.72572e-13
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00267454
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00298834
metacluster_1/pattern_110.0244574
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00234363
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00447304
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00105766
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00162358
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00661124
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00312431
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00279199
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_90.038486400000000004
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_90.020212900000000002
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_90.032874900000000006
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00330304
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00364646
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00643235
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.019199200000000003
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0123833
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.038486400000000004
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0478517
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_90.049834300000000005
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_90.049834300000000005
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_90.049834300000000005
Arnt2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05534209999999999
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00505854
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00017942299999999998
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00034144199999999996
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000677525
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_110.018993299999999998
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.043629699999999993
Tfap2c
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0475745
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_124.63358e-05
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0012322000000000001
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_131.51686e-07
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000117671
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00104355
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00167854
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_152.35792e-07
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_155.528830000000001e-06
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_156.0168900000000006e-05
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_156.0168900000000006e-05
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0129531
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_161.38689e-10
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_165.0756400000000005e-09
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00039632400000000004
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00010180299999999999
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00022191799999999999
Zfp322a
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0242884
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0406728
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #71
TF NameModiscoHomer
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_81.72572e-13
Pattern NameHomerSignificance
motif5.motif3.3405699999999994e-06
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00393792
Pattern NameHomerSignificance
motif3.motif0.0342222
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_27.964069999999998e-06
metacluster_1/pattern_60.00771159
metacluster_1/pattern_112.60324e-08
Pattern NameHomerSignificance
motif2.motif0.00044251800000000003
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013165799999999998
metacluster_1/pattern_79.28323e-06
Pattern NameHomerSignificance
motif12.motif0.00874111
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00691944
metacluster_1/pattern_70.00932996
Pattern NameHomerSignificance
motif12.motif0.0114133
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0037626999999999995
Pattern NameHomerSignificance
motif3.motif0.00365171
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00021448900000000003
Pattern NameHomerSignificance
motif3.motif0.0006942469999999999
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_15.3788999999999996e-05
Pattern NameHomerSignificance
motif3.motif4.6639e-05
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_18.16204e-05
Pattern NameHomerSignificance
motif3.motif5.24e-05
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0178123
metacluster_1/pattern_110.000452472
Pattern NameHomerSignificance
motif2.motif0.00088293
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0178123
metacluster_1/pattern_110.0255448
Pattern NameHomerSignificance
motif2.motif0.0587454
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000537819
metacluster_1/pattern_60.00771159
metacluster_1/pattern_110.00282741
Pattern NameHomerSignificance
motif2.motif0.00684435
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00132864
metacluster_1/pattern_110.000801092
Pattern NameHomerSignificance
motif2.motif0.00150401
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0316149
metacluster_1/pattern_30.037155
metacluster_1/pattern_60.00771159
metacluster_1/pattern_110.0153803
Pattern NameHomerSignificance
motif2.motif0.0154451
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_13.81685e-05
Pattern NameHomerSignificance
motif3.motif0.000699721
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00836844
Pattern NameHomerSignificance
motif15.motif0.051125300000000005
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0574145
metacluster_1/pattern_110.00661846
Pattern NameHomerSignificance
motif2.motif0.025806799999999998
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_44.96156e-15
Pattern NameHomerSignificance
motif4.motif0.0567326
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0087715
Pattern NameHomerSignificance
motif12.motif0.019677700000000003
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.71368e-05
metacluster_1/pattern_112.93567e-07
Pattern NameHomerSignificance
motif2.motif0.00044251800000000003
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.017058900000000002
metacluster_1/pattern_70.022825400000000003
Pattern NameHomerSignificance
motif3.motif0.00239664
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00550988
Pattern NameHomerSignificance
motif12.motif0.00874111
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00040407
metacluster_1/pattern_110.05001919999999999
Pattern NameHomerSignificance
motif3.motif0.000392486
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_81.11357e-21
Pattern NameHomerSignificance
motif5.motif3.07612e-08
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_50.034642
Pattern NameHomerSignificance
motif15.motif0.014058700000000002
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000537819
metacluster_1/pattern_112.0756799999999998e-05
Pattern NameHomerSignificance
motif2.motif0.001394
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000729038
metacluster_1/pattern_70.0012075
Pattern NameHomerSignificance
motif3.motif0.0568245
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00385736
Pattern NameHomerSignificance
motif15.motif0.0572586
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.5933400000000002e-07
Pattern NameHomerSignificance
motif6.motif1.5414600000000001e-06
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00021223900000000003
metacluster_1/pattern_78.50796e-15
Pattern NameHomerSignificance
motif12.motif3.06436e-09
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019330200000000001
Pattern NameHomerSignificance
motif3.motif0.000335687
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_44.32823e-11
Pattern NameHomerSignificance
motif4.motif0.0536765
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00768817
metacluster_1/pattern_70.022825400000000003
Pattern NameHomerSignificance
motif12.motif0.05516569999999999
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_70.018453599999999997
Pattern NameHomerSignificance
motif12.motif0.045275
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_13.82528e-05
Pattern NameHomerSignificance
motif3.motif0.000351391
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0179171
Pattern NameHomerSignificance
motif15.motif0.0585102
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0574145
metacluster_1/pattern_60.05381609999999999
metacluster_1/pattern_110.0267967
Pattern NameHomerSignificance
motif2.motif0.0587454
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0165226
metacluster_1/pattern_110.00040052400000000003
Pattern NameHomerSignificance
motif2.motif0.025806799999999998
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00110966
Pattern NameHomerSignificance
motif3.motif0.0187602
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.008317299999999998
metacluster_1/pattern_90.00921443
Pattern NameHomerSignificance
motif15.motif0.05139
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00021223900000000003
metacluster_1/pattern_70.0286895
Pattern NameHomerSignificance
motif12.motif4.43825e-08
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_02.4583e-13
Pattern NameHomerSignificance
motif1.motif1.99303e-05
motif8.motif0.040582599999999996
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_23.50889e-06
metacluster_1/pattern_30.0288801
metacluster_1/pattern_60.000235913
metacluster_1/pattern_111.1452900000000001e-10
Pattern NameHomerSignificance
motif2.motif0.000412021
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000236309
Pattern NameHomerSignificance
motif3.motif5.87317e-05
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_13.81685e-05
Pattern NameHomerSignificance
motif3.motif0.00268081
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_13.81685e-05
metacluster_1/pattern_72.95968e-08
Pattern NameHomerSignificance
motif3.motif0.050224300000000006
motif12.motif1.13951e-05
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0563428
Pattern NameHomerSignificance
motif15.motif0.0587057
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000137048
Pattern NameHomerSignificance
motif3.motif1.5240899999999998e-05
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_124.63358e-05
Pattern NameHomerSignificance
motif13.motif8.33577e-06
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.014472399999999998
metacluster_1/pattern_70.0006076380000000001
Pattern NameHomerSignificance
motif12.motif0.0424552
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0049218000000000005
Pattern NameHomerSignificance
motif3.motif0.00908761
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0007614610000000001
metacluster_1/pattern_110.0007551389999999999
Pattern NameHomerSignificance
motif2.motif0.000873975
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00467782
Pattern NameHomerSignificance
motif3.motif0.00308315
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_81.7728800000000003e-21
Pattern NameHomerSignificance
motif5.motif5.1314199999999996e-08
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0005097480000000001
metacluster_1/pattern_110.00907386
Pattern NameHomerSignificance
motif2.motif0.00044251800000000003
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0006106169999999999
metacluster_1/pattern_70.018606400000000002
Pattern NameHomerSignificance
motif3.motif0.00952661
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00774309
Pattern NameHomerSignificance
motif12.motif0.014672799999999998
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_04.519419999999999e-08
metacluster_1/pattern_110.055947500000000004
Pattern NameHomerSignificance
motif1.motif0.00020255700000000002
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0007779989999999999
metacluster_1/pattern_70.0548303
Pattern NameHomerSignificance
motif3.motif0.012488299999999999
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00434427
Pattern NameHomerSignificance
motif15.motif0.00976934
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0251145
metacluster_1/pattern_110.00018481700000000002
Pattern NameHomerSignificance
motif2.motif0.0389916
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019330200000000001
Pattern NameHomerSignificance
motif3.motif0.0032624000000000004
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000109175
Pattern NameHomerSignificance
motif3.motif4.1421499999999996e-05
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00012223100000000002
Pattern NameHomerSignificance
motif3.motif0.00043637900000000003
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.047954699999999996
Pattern NameHomerSignificance
motif15.motif0.0201543
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0126131
Pattern NameHomerSignificance
motif3.motif0.00737728
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_50.035407
Pattern NameHomerSignificance
motif15.motif0.0391629
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00160998
metacluster_1/pattern_110.012136599999999999
Pattern NameHomerSignificance
motif2.motif0.025806799999999998
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019330200000000001
Pattern NameHomerSignificance
motif3.motif0.000982675
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00705912
Pattern NameHomerSignificance
motif12.motif0.0124507
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00334506
metacluster_1/pattern_90.0589352
Pattern NameHomerSignificance
motif15.motif0.05139
Unique TF-MoDISco TFs: #61
TF NameModiscoHomer
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00364646
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0205423
metacluster_1/pattern_118.16315e-06
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00505854
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.019199200000000003
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_131.51686e-07
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00034144199999999996
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0131434
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000117671
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0123833
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_165.0756400000000005e-09
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00298834
metacluster_1/pattern_110.0244574
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_110.018993299999999998
Absent
Tfap2c
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0475745
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0129531
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00924289
metacluster_1/pattern_132.2254499999999999e-13
Absent
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_155.528830000000001e-06
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00162358
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00105766
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_161.38689e-10
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00312431
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00017942299999999998
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0012322000000000001
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00167854
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00661124
Absent
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.06308e-06
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_90.020212900000000002
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_90.049834300000000005
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.038486400000000004
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00267454
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_90.049834300000000005
Absent
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_44.82279e-07
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00330304
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.043629699999999993
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00234363
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0574145
metacluster_1/pattern_110.00300457
Absent
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_43.5931300000000005e-12
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_90.049834300000000005
Absent
Arnt2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05534209999999999
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00039632400000000004
Absent
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_156.0168900000000006e-05
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0272614
metacluster_1/pattern_110.00265236
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0116559
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_90.032874900000000006
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0406728
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00447304
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00010180299999999999
Absent
Zfp322a
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0242884
Absent
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_152.35792e-07
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00709576
metacluster_1/pattern_110.000572312
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00104355
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000677525
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.06308e-06
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00225013
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0478517
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_90.038486400000000004
Absent
Gmeb2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0447726
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00643235
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00022191799999999999
Absent
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_42.40522e-06
Absent
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_156.0168900000000006e-05
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00279199
Absent
Unique Homer TFs: #12
TF NameModiscoHomer
CebpdAbsent
Pattern NameHomerSignificance
motif15.motif0.0587057
Atf4Absent
Pattern NameHomerSignificance
motif15.motif0.0587057
CebpbAbsent
Pattern NameHomerSignificance
motif15.motif0.0587057
JundAbsent
Pattern NameHomerSignificance
motif15.motif0.0437385
CebpaAbsent
Pattern NameHomerSignificance
motif15.motif0.0587057
Fosl1Absent
Pattern NameHomerSignificance
motif15.motif0.014333700000000001
Irf6Absent
Pattern NameHomerSignificance
motif3.motif0.0582323
Zbtb1Absent
Pattern NameHomerSignificance
motif2.motif0.0587454
Runx2Absent
Pattern NameHomerSignificance
motif17.motif0.030088999999999998
CebpgAbsent
Pattern NameHomerSignificance
motif15.motif0.0587057
CebpeAbsent
Pattern NameHomerSignificance
motif15.motif0.0587057
Ddit3Absent
Pattern NameHomerSignificance
motif15.motif0.0587057