In [1]:
# Parameters
data_name = "aNonTfh;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_26-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_26-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:45:26,284 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeactivated non-Tfh (CD4+CD44+CXCR5-PD1-CD25-) WT
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep11069478577011.885855573249113935860.205183330360.15172650350.3108
    Modelling Metadata
    MetricValue
    auPRC0.6142
    Calibrated Recall at 50% FDR0.208
    Number of Positive Examples in Test Data93110
    Number of Negative Examples in Test Data7977741
    Imbalance Ratio in Test Data0.0115
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #21
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5920 SequenceContrib ScoresHyp_Contrib Scores
Erg, Ets1, Fli1, Etv4, Elk1, Etv2, Gabpa, Elk4, Etv5, Elk3,

Etv6, Spi1, Etv3, XP_911724.4, Fev, Etv1, Elf2, Elf1, Elf4, Spib, Ehf,

Elf5, Elf3, Spdef, Spic, Irf8, Irf4, Stat3, Stat4, Zscan10, Stat6
metacluster_1/pattern_1 # seqlets: 5566 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 3494 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Klf4, Klf8,

Klf12, Klf1, Egr1, Zbtb17, Egr2, E2f1, Sp5, Klf5, Zfp281, Zfx, Zfp740,

Egr3, Zbtb1
metacluster_1/pattern_3 # seqlets: 1507 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Stat1, Prdm1, Irf7, Stat2, Irf3, Irf9, Batf3
metacluster_1/pattern_4 # seqlets: 1234 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_5 # seqlets: 1210 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_6 # seqlets: 990 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_7 # seqlets: 761 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Usf2, Crem, Atf2, Jdp2, Atf7, Atf1, Creb5, Atf3, Fosl2,

Jun, Fosl1, Nfil3
metacluster_1/pattern_8 # seqlets: 679 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42, Rfx1, Wt1
metacluster_1/pattern_9 # seqlets: 673 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_10 # seqlets: 620 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_11 # seqlets: 594 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfe3, Tfeb, Arntl, Tfec, Mitf, Bhlhe40, Srebf1, Arnt, Clock,

Mlx, Npas2, Srebf2, Creb3l2, Tcfl5, Mycn, Max, Myc, Bhlhe41, Hlf, Rarg,

Dbp, Xbp1
metacluster_1/pattern_12 # seqlets: 388 SequenceContrib ScoresHyp_Contrib Scores
Fosb, Junb, Fos, Jund, Batf, Bach2, Nfe2, Nfe2l2, Bach1, Mafa,

Mafk
metacluster_1/pattern_13 # seqlets: 332 SequenceContrib ScoresHyp_Contrib Scores
Nfkb1, Rela, Relb, Nfkb2, Rel
metacluster_1/pattern_14 # seqlets: 327 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_15 # seqlets: 184 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 174 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_17 # seqlets: 148 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_18 # seqlets: 143 SequenceContrib ScoresHyp_Contrib Scores
Tcf7l2, Lef1, Tcf3, Tcf7l1, Tcf7
metacluster_1/pattern_19 # seqlets: 120 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_20 # seqlets: 61 SequenceContrib ScoresHyp_Contrib Scores
Gata3, Gata1, Gata2, Gata4
Click here for Motifs by TF-MoDISco: #151
TF NamePattern(s)
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000792175
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000809924
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000792175
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000869335
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00097939
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_06.0443000000000004e-05
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00104773
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000900447
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00019674400000000003
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000900447
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000792175
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.052601999999999996
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00081319
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00081319
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000839949
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000938395
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00587191
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00342977
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00361981
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00519478
metacluster_1/pattern_30.00111381
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00841542
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0242027
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0213935
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.015313499999999999
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05539259999999999
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0242027
metacluster_1/pattern_32.81801e-06
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.026798900000000004
metacluster_1/pattern_30.040849
Stat3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0508471
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0508471
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05184400000000001
Stat6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05184400000000001
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_14.93665e-16
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_11.54488e-07
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00150026
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_24.14162e-06
metacluster_1/pattern_82.1038e-05
metacluster_1/pattern_190.00344966
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.0702e-05
metacluster_1/pattern_80.00104997
metacluster_1/pattern_190.0100867
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.97085e-05
metacluster_1/pattern_80.057765
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00043538400000000003
metacluster_1/pattern_80.000636621
metacluster_1/pattern_190.017106599999999996
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00043538400000000003
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000667889
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000710158
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0129386
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000949373
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.012822499999999999
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0466907
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0343834
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00613507
metacluster_1/pattern_80.0103677
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.036896899999999996
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.013030400000000001
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0209419
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0209419
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0239952
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.034801
metacluster_1/pattern_40.043216199999999996
metacluster_1/pattern_80.0103677
metacluster_1/pattern_190.017106599999999996
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.035835900000000004
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0466907
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.055245100000000005
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_33.3011199999999994e-16
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000923545
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.9764000000000003e-05
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_37.95663e-05
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000115365
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000461035
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00062195
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00210778
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0101719
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_47.14913e-06
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_56.11788e-13
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_51.711e-09
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_51.4459799999999998e-08
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_54.515e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_54.515e-06
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.000365844
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.010081399999999999
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00157796
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00402269
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_60.036359800000000005
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00140417
metacluster_1/pattern_110.0253731
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000315049
metacluster_1/pattern_110.00631051
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_70.013834299999999999
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00122105
metacluster_1/pattern_110.0488168
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0016640000000000001
metacluster_1/pattern_110.05797080000000001
metacluster_1/pattern_126.94988e-05
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000679433
metacluster_1/pattern_110.028618400000000002
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0156969
metacluster_1/pattern_110.0213227
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00206115
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00770719
metacluster_1/pattern_123.04501e-06
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0163039
metacluster_1/pattern_128.34597e-05
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0249885
metacluster_1/pattern_120.0331514
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0325309
metacluster_1/pattern_120.046943900000000004
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.043317699999999994
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_83.03938e-06
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_85.47164e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0103677
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026092
metacluster_1/pattern_145.07226e-08
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0376409
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_99.85074e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_99.85074e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_98.62329e-14
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.012068299999999999
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000611476
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00019024099999999998
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00750382
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000612716
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000379239
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_110.013743100000000001
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.023851400000000002
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0488168
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_110.010904700000000002
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00634181
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00415995
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00634181
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0226979
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0107639
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0119043
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_110.017221200000000002
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0213227
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0242378
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0342621
Rarg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0342621
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_110.050628
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0590319
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_121.00694e-06
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.024166999999999998
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_121.57882e-06
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0044115000000000005
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00760641
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00214692
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00442948
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00461042
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00524975
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_120.038400800000000006
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_120.047356199999999994
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_137.3535e-05
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000266747
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000266747
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000266747
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_130.017763
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.018855
metacluster_1/pattern_150.000375361
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_143.8717300000000005e-08
metacluster_1/pattern_152.77836e-07
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_149.92073e-05
metacluster_1/pattern_150.0101374
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0103073
metacluster_1/pattern_150.00624543
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.012444799999999999
metacluster_1/pattern_150.00399451
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.17354e-05
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_180.049058
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00012270100000000002
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0017858000000000001
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0158412
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_198.351230000000001e-06
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_200.031261000000000004
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_200.0152119
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_200.0152119
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_200.0375227
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #80
TF NameModiscoHomer
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000612716
Pattern NameHomerSignificance
motif17.motif0.00485266
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00750382
Pattern NameHomerSignificance
motif17.motif0.020060400000000003
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00587191
Pattern NameHomerSignificance
motif2.motif0.0300466
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.012068299999999999
Pattern NameHomerSignificance
motif17.motif0.024828
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_85.47164e-06
Pattern NameHomerSignificance
motif16.motif3.3363500000000004e-07
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000809924
Pattern NameHomerSignificance
motif2.motif1.1687999999999999e-05
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000900447
Pattern NameHomerSignificance
motif2.motif0.00021961900000000003
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0213935
Pattern NameHomerSignificance
motif2.motif0.0482175
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000949373
Pattern NameHomerSignificance
motif3.motif0.00185463
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00019674400000000003
Pattern NameHomerSignificance
motif2.motif3.97755e-07
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.023851400000000002
Pattern NameHomerSignificance
motif17.motif0.04191690000000001
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00043538400000000003
Pattern NameHomerSignificance
motif3.motif0.000391171
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00043538400000000003
metacluster_1/pattern_80.000636621
metacluster_1/pattern_190.017106599999999996
Pattern NameHomerSignificance
motif3.motif0.00961274
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.034801
metacluster_1/pattern_40.043216199999999996
metacluster_1/pattern_80.0103677
metacluster_1/pattern_190.017106599999999996
Pattern NameHomerSignificance
motif3.motif0.023461799999999998
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_51.4459799999999998e-08
Pattern NameHomerSignificance
motif9.motif0.000159149
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_54.515e-06
Pattern NameHomerSignificance
motif9.motif0.00849387
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0466907
Pattern NameHomerSignificance
motif3.motif0.0592615
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0103677
Pattern NameHomerSignificance
motif16.motif0.00128259
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_06.0443000000000004e-05
Pattern NameHomerSignificance
motif2.motif0.000798795
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_51.711e-09
Pattern NameHomerSignificance
motif9.motif0.000159149
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0156969
metacluster_1/pattern_110.0213227
Pattern NameHomerSignificance
motif17.motif0.0260503
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_14.93665e-16
Pattern NameHomerSignificance
motif1.motif0.00050998
motif10.motif0.0173901
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_99.85074e-21
Pattern NameHomerSignificance
motif5.motif5.458049999999999e-06
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00361981
Pattern NameHomerSignificance
motif2.motif0.0039343
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.015313499999999999
Pattern NameHomerSignificance
motif2.motif0.011665700000000001
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000869335
Pattern NameHomerSignificance
motif2.motif0.00262532
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000938395
Pattern NameHomerSignificance
motif2.motif5.16364e-07
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_11.54488e-07
Pattern NameHomerSignificance
motif1.motif0.000999071
motif10.motif0.0173901
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00104773
Pattern NameHomerSignificance
motif2.motif0.00349393
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_56.11788e-13
Pattern NameHomerSignificance
motif9.motif8.77902e-06
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_110.013743100000000001
Pattern NameHomerSignificance
motif17.motif0.00793707
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0242378
Pattern NameHomerSignificance
motif17.motif0.015547
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000679433
metacluster_1/pattern_110.028618400000000002
Pattern NameHomerSignificance
motif17.motif0.0193968
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00081319
Pattern NameHomerSignificance
motif2.motif7.91426e-05
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0119043
Pattern NameHomerSignificance
motif17.motif0.0558342
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000792175
Pattern NameHomerSignificance
motif2.motif0.00366927
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_47.14913e-06
Pattern NameHomerSignificance
motif13.motif6.3637699999999996e-06
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00019024099999999998
Pattern NameHomerSignificance
motif17.motif0.0006889610000000001
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00613507
metacluster_1/pattern_80.0103677
Pattern NameHomerSignificance
motif3.motif0.0567235
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0242027
Pattern NameHomerSignificance
motif2.motif0.0554383
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0129386
Pattern NameHomerSignificance
motif3.motif0.000806862
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00081319
Pattern NameHomerSignificance
motif2.motif0.00010675
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000611476
Pattern NameHomerSignificance
motif17.motif0.00452897
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0226979
Pattern NameHomerSignificance
motif17.motif0.0562826
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00342977
Pattern NameHomerSignificance
motif2.motif0.0131256
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00122105
metacluster_1/pattern_110.0488168
Pattern NameHomerSignificance
motif17.motif0.0274176
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00097939
Pattern NameHomerSignificance
motif2.motif0.000166025
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0343834
Pattern NameHomerSignificance
motif3.motif0.0310612
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.012822499999999999
Pattern NameHomerSignificance
motif3.motif0.0241411
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_24.14162e-06
metacluster_1/pattern_82.1038e-05
metacluster_1/pattern_190.00344966
Pattern NameHomerSignificance
motif3.motif0.00012102
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0107639
Pattern NameHomerSignificance
motif17.motif0.0101194
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00140417
metacluster_1/pattern_110.0253731
Pattern NameHomerSignificance
motif17.motif0.0278634
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_99.85074e-21
Pattern NameHomerSignificance
motif5.motif2.5137599999999997e-06
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000792175
Pattern NameHomerSignificance
motif2.motif3.49114e-06
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.97085e-05
metacluster_1/pattern_80.057765
Pattern NameHomerSignificance
motif3.motif0.00019989099999999997
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0488168
Pattern NameHomerSignificance
motif17.motif0.0481705
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000792175
Pattern NameHomerSignificance
motif2.motif2.64887e-05
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0209419
Pattern NameHomerSignificance
motif3.motif0.0310612
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000900447
Pattern NameHomerSignificance
motif2.motif3.49114e-06
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00415995
Pattern NameHomerSignificance
motif17.motif0.00507246
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000379239
Pattern NameHomerSignificance
motif17.motif0.00225261
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0342621
Pattern NameHomerSignificance
motif17.motif0.0593328
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00841542
Pattern NameHomerSignificance
motif2.motif0.00561101
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000710158
Pattern NameHomerSignificance
motif3.motif0.000806862
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_83.03938e-06
Pattern NameHomerSignificance
motif16.motif0.00042156800000000004
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00634181
Pattern NameHomerSignificance
motif17.motif0.00481242
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00150026
Pattern NameHomerSignificance
motif3.motif0.033823
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00634181
Pattern NameHomerSignificance
motif17.motif0.018650999999999997
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_198.351230000000001e-06
Pattern NameHomerSignificance
motif15.motif0.000488899
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.0702e-05
metacluster_1/pattern_80.00104997
metacluster_1/pattern_190.0100867
Pattern NameHomerSignificance
motif3.motif0.000273948
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_98.62329e-14
Pattern NameHomerSignificance
motif5.motif5.39434e-05
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_54.515e-06
Pattern NameHomerSignificance
motif9.motif0.00285157
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000315049
metacluster_1/pattern_110.00631051
Pattern NameHomerSignificance
motif17.motif0.0363415
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.013030400000000001
Pattern NameHomerSignificance
motif3.motif0.047065499999999996
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000667889
Pattern NameHomerSignificance
motif3.motif0.000487449
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000839949
Pattern NameHomerSignificance
motif2.motif0.00349393
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_70.013834299999999999
Pattern NameHomerSignificance
motif17.motif0.039651900000000004
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05539259999999999
Pattern NameHomerSignificance
motif2.motif0.0430406
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_110.010904700000000002
Pattern NameHomerSignificance
motif17.motif0.024828
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_110.017221200000000002
Pattern NameHomerSignificance
motif17.motif0.0433901
Unique TF-MoDISco TFs: #71
TF NameModiscoHomer
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0103073
metacluster_1/pattern_150.00624543
Absent
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00012270100000000002
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0590319
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00206115
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.018855
metacluster_1/pattern_150.000375361
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00770719
metacluster_1/pattern_123.04501e-06
Absent
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0508471
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0213227
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.010081399999999999
Absent
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00519478
metacluster_1/pattern_30.00111381
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_130.017763
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_121.00694e-06
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0101719
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0209419
Absent
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0017858000000000001
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0163039
metacluster_1/pattern_128.34597e-05
Absent
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_60.036359800000000005
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026092
metacluster_1/pattern_145.07226e-08
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.9764000000000003e-05
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_33.3011199999999994e-16
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0376409
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00524975
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00461042
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0242027
metacluster_1/pattern_32.81801e-06
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_120.038400800000000006
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0325309
metacluster_1/pattern_120.046943900000000004
Absent
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.052601999999999996
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0044115000000000005
Absent
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_137.3535e-05
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0249885
metacluster_1/pattern_120.0331514
Absent
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_200.031261000000000004
Absent
Rarg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0342621
Absent
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.17354e-05
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000115365
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_120.047356199999999994
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.000365844
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0466907
Absent
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000266747
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.043317699999999994
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.035835900000000004
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0239952
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00210778
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00157796
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0016640000000000001
metacluster_1/pattern_110.05797080000000001
metacluster_1/pattern_126.94988e-05
Absent
Stat6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05184400000000001
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_37.95663e-05
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05184400000000001
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000461035
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.026798900000000004
metacluster_1/pattern_30.040849
Absent
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_180.049058
Absent
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_200.0375227
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_200.0152119
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_143.8717300000000005e-08
metacluster_1/pattern_152.77836e-07
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00062195
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_110.050628
Absent
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0158412
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.024166999999999998
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00760641
Absent
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_200.0152119
Absent
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000266747
Absent
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.055245100000000005
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.036896899999999996
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00442948
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00214692
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00402269
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.012444799999999999
metacluster_1/pattern_150.00399451
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000923545
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_149.92073e-05
metacluster_1/pattern_150.0101374
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_121.57882e-06
Absent
Stat3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0508471
Absent
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000266747
Absent
Unique Homer TFs: #2
TF NameModiscoHomer
Irf6Absent
Pattern NameHomerSignificance
motif2.motif0.0482175
E2f7Absent
Pattern NameHomerSignificance
motif3.motif0.05601849999999999