In [1]:
# Parameters
data_name = "DP3b;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_48-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_48-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:50:41,867 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeDN3b
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1135393997539.203256525046101949660.180465348290.1156199684450.3534
    Modelling Metadata
    MetricValue
    auPRC0.582
    Calibrated Recall at 50% FDR0.247
    Number of Positive Examples in Test Data105288
    Number of Negative Examples in Test Data7965563
    Imbalance Ratio in Test Data0.013
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #18
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5084 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4061 SequenceContrib ScoresHyp_Contrib Scores
Ets1, Erg, Elk1, Etv2, Etv4, Gabpa, Elk4, Fli1, Elf2, Spi1,

Etv6, Elk3, Ehf, Etv5, Spib, Fev, Elf1, Elf3, Etv1, Etv3, XP_911724.4,

Elf4, Ets2, Irf8, Irf4, Stat4, Elf5, Spic
metacluster_1/pattern_2 # seqlets: 3263 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp3, Klf3, Sp4, Sp1, Klf6, Zfx, Klf15, Wt1, Klf1,

Egr1, Maz, Sp5, E2f4, Zfp281, Klf5, Zbtb17, Klf4, Klf7, Klf8, Klf12,

Usf2, Egr2, Tfap2c, E2f1, Nr1h4, Ptf1a, Srebf2
metacluster_1/pattern_3 # seqlets: 1705 SequenceContrib ScoresHyp_Contrib Scores
Tcf3, Snai2, Myf6, Tcf4, Ascl2, Ascl1, Tcf12, Tcf7l1, Myog, Myod1,

Mnt, Nhlh2, Snai1, Pknox2, Hes5, Myf5, Tal1, Meis2, Meis3, Bhlha15, Nhlh1,

Hey2, Figla
metacluster_1/pattern_4 # seqlets: 1545 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_5 # seqlets: 1495 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_6 # seqlets: 1160 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Foxi1, Nfyc, Nfya, Pbx3
metacluster_1/pattern_7 # seqlets: 958 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Stat1, Irf7, Prdm1, Irf3, Stat2, Irf9, Batf3
metacluster_1/pattern_8 # seqlets: 728 SequenceContrib ScoresHyp_Contrib Scores
Tcf7l2, Lef1, Tcf7
metacluster_1/pattern_9 # seqlets: 609 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_10 # seqlets: 591 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_11 # seqlets: 567 SequenceContrib ScoresHyp_Contrib Scores
Hes7, Hes1
metacluster_1/pattern_12 # seqlets: 496 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfe3, Tfeb, Arntl, Tfec, Mitf, Srebf1, Bhlhe40, Clock, Arnt,

Mlx, Npas2, Creb3l2, Tcfl5, Mycn, Max, Bhlhe41, Atf1, Myc, Creb1, Atf7,

Hlf, Atf2, Jdp2, Xbp1, Dbp
metacluster_1/pattern_13 # seqlets: 481 SequenceContrib ScoresHyp_Contrib Scores
Creb5, Crem, Atf3, Mafb, Fosl2, Nfil3, Fosl1, Rxrb, Tef, Jun
metacluster_1/pattern_14 # seqlets: 322 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx1, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_15 # seqlets: 75 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib, Nfic
metacluster_1/pattern_16 # seqlets: 64 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_1/pattern_17 # seqlets: 37 SequenceContrib ScoresHyp_Contrib Scores
Rest
Click here for Motifs by TF-MoDISco: #156
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_03.5321599999999998e-15
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_01.6984300000000002e-07
metacluster_1/pattern_20.0334749
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00460709
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00538905
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_16.02649e-05
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00618203
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0292279
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00150557
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00376291
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00538465
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.027097900000000005
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00199589
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00238427
metacluster_1/pattern_70.000793946
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0026249000000000003
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00274455
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0588376
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00560403
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00541096
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00541096
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0198924
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0201952
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0202269
metacluster_1/pattern_75.79153e-07
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0236425
metacluster_1/pattern_70.0177266
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0236425
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0292279
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0474764
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_27.76322e-16
metacluster_1/pattern_110.00111729
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.36031e-11
metacluster_1/pattern_110.00111729
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_23.32086e-09
metacluster_1/pattern_110.00111729
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00181208
metacluster_1/pattern_110.00969551
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00037341800000000004
metacluster_1/pattern_110.00544475
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_21.27558e-06
metacluster_1/pattern_110.00552529
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00311226
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_23.78833e-05
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_24.5932299999999994e-05
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0545442
metacluster_1/pattern_110.00705968
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00522253
metacluster_1/pattern_110.034899
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_29.84279e-05
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00014897899999999998
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00023757400000000003
metacluster_1/pattern_110.00811986
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000406897
metacluster_1/pattern_110.0117632
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00031786900000000003
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00040177699999999997
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00181208
metacluster_1/pattern_110.00870276
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00130487
metacluster_1/pattern_110.00111729
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00256444
metacluster_1/pattern_110.00111729
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00275033
metacluster_1/pattern_110.00145126
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00522253
metacluster_1/pattern_120.00483844
metacluster_1/pattern_130.054269000000000005
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00577678
Tfap2c
Pattern NameModiscoSignificance
metacluster_1/pattern_20.012787799999999998
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0230542
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0264022
Ptf1a
Pattern NameModiscoSignificance
metacluster_1/pattern_20.05613390000000001
metacluster_1/pattern_30.034707800000000004
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0584581
metacluster_1/pattern_120.00406913
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00365116
metacluster_1/pattern_80.000255218
Snai2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0008074530000000001
Myf6
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0170666
Tcf4
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00342266
Ascl2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00430314
Ascl1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.010946
Tcf12
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0172262
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0108498
metacluster_1/pattern_80.000142318
Myog
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0485564
Myod1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.013581799999999998
Mnt
Pattern NameModiscoSignificance
metacluster_1/pattern_30.016134700000000002
Nhlh2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0170666
Snai1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0170666
Pknox2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029129900000000004
Hes5
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029129900000000004
Myf5
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029129900000000004
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029555099999999997
Meis2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0337202
Meis3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0337202
Bhlha15
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0337202
Nhlh1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.034707800000000004
Hey2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.041562
Figla
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0521827
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00283144
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.023250999999999997
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00155753
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_40.002522
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0524587
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.06088e-09
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_61.7968000000000002e-10
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.6711800000000004e-06
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_63.6711800000000004e-06
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_65.03474e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.000109329
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_72.3498e-15
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0014314
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_75.56236e-06
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_73.86165e-05
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_73.86165e-05
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000156618
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000409749
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00298629
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.010110899999999999
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00621544
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_83.81298e-07
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00827321
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_108.401469999999999e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_102.7581299999999997e-20
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_108.11808e-14
Hes7
Pattern NameModiscoSignificance
metacluster_1/pattern_110.031281
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0336632
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00764738
metacluster_1/pattern_130.023316
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00185733
metacluster_1/pattern_130.03157
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000551344
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00588852
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00185733
metacluster_1/pattern_130.057020600000000005
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0010911
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.026796299999999995
metacluster_1/pattern_130.03157
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0114222
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0297029
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0457275
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0138658
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00266436
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0201697
metacluster_1/pattern_130.029016900000000005
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00928325
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0110242
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0138773
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0203212
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0203212
metacluster_1/pattern_130.0349701
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0217022
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.044083
metacluster_1/pattern_130.00276107
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0268731
metacluster_1/pattern_130.00036275099999999997
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0312873
metacluster_1/pattern_130.0250894
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.039521
metacluster_1/pattern_130.000851192
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.056124
metacluster_1/pattern_130.000763636
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0439444
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_120.056124
metacluster_1/pattern_130.027562
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000403269
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00771041
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0214558
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00641657
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.015142099999999999
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0250972
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0270756
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.027562
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_130.032253
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_130.032253
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00162291
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_143.49476e-11
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_144.77914e-08
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00015209
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00147337
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0006409230000000001
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_153.02846e-06
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_153.02846e-06
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00317992
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00663835
Rest
Pattern NameModiscoSignificance
metacluster_1/pattern_171.3421099999999999e-13
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #67
TF NameModiscoHomer
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00014897899999999998
Pattern NameHomerSignificance
motif3.motif0.0408507
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00199589
Pattern NameHomerSignificance
motif2.motif3.0190500000000002e-05
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_63.6711800000000004e-06
Pattern NameHomerSignificance
motif8.motif2.92662e-06
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_23.78833e-05
Pattern NameHomerSignificance
motif3.motif0.00431723
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0588376
Pattern NameHomerSignificance
motif2.motif0.0180286
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00256444
metacluster_1/pattern_110.00111729
Pattern NameHomerSignificance
motif3.motif0.000674627
Snai1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0170666
Pattern NameHomerSignificance
motif1.motif0.0530831
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.06088e-09
Pattern NameHomerSignificance
motif11.motif2.26525e-05
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_27.76322e-16
metacluster_1/pattern_110.00111729
Pattern NameHomerSignificance
motif3.motif0.000114377
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_65.03474e-06
Pattern NameHomerSignificance
motif8.motif2.4281e-06
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00538465
Pattern NameHomerSignificance
motif2.motif0.000454275
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_102.7581299999999997e-20
Pattern NameHomerSignificance
motif5.motif1.50652e-05
Myog
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0485564
Pattern NameHomerSignificance
motif7.motif0.0585529
Myf6
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0170666
Pattern NameHomerSignificance
motif7.motif0.0265288
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.6711800000000004e-06
Pattern NameHomerSignificance
motif8.motif0.00123968
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00181208
metacluster_1/pattern_110.00969551
Pattern NameHomerSignificance
motif3.motif0.00798451
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0230542
Pattern NameHomerSignificance
motif3.motif0.00560742
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0292279
Pattern NameHomerSignificance
motif2.motif0.00368158
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00037341800000000004
metacluster_1/pattern_110.00544475
Pattern NameHomerSignificance
motif3.motif0.0027416
Mnt
Pattern NameModiscoSignificance
metacluster_1/pattern_30.016134700000000002
Pattern NameHomerSignificance
motif7.motif0.0585529
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.000109329
Pattern NameHomerSignificance
motif8.motif0.0005696319999999999
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0026249000000000003
Pattern NameHomerSignificance
motif2.motif0.000513582
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00460709
Pattern NameHomerSignificance
motif2.motif0.000454275
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_23.32086e-09
metacluster_1/pattern_110.00111729
Pattern NameHomerSignificance
motif3.motif0.000296424
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_16.02649e-05
Pattern NameHomerSignificance
motif2.motif5.8001e-05
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00577678
Pattern NameHomerSignificance
motif3.motif0.026122500000000003
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00130487
metacluster_1/pattern_110.00111729
Pattern NameHomerSignificance
motif3.motif0.000296424
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00560403
Pattern NameHomerSignificance
motif2.motif0.000454275
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_21.27558e-06
metacluster_1/pattern_110.00552529
Pattern NameHomerSignificance
motif3.motif0.000891893
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00522253
metacluster_1/pattern_110.034899
Pattern NameHomerSignificance
motif3.motif0.0486077
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Pattern NameHomerSignificance
motif2.motif0.000454275
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Pattern NameHomerSignificance
motif2.motif0.000454275
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_03.5321599999999998e-15
Pattern NameHomerSignificance
motif1.motif2.93967e-06
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00538905
Pattern NameHomerSignificance
motif2.motif0.000454275
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Pattern NameHomerSignificance
motif2.motif0.000513582
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.023250999999999997
Pattern NameHomerSignificance
motif4.motif0.0418237
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000406897
metacluster_1/pattern_110.0117632
Pattern NameHomerSignificance
motif3.motif0.0534714
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_108.401469999999999e-21
Pattern NameHomerSignificance
motif5.motif2.58111e-05
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00238427
metacluster_1/pattern_70.000793946
Pattern NameHomerSignificance
motif2.motif0.00653515
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.36031e-11
metacluster_1/pattern_110.00111729
Pattern NameHomerSignificance
motif3.motif3.51376e-05
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0474764
Pattern NameHomerSignificance
motif2.motif0.0435964
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00181208
metacluster_1/pattern_110.00870276
Pattern NameHomerSignificance
motif3.motif0.0249105
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00365116
metacluster_1/pattern_80.000255218
Pattern NameHomerSignificance
motif7.motif0.0585529
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_61.7968000000000002e-10
Pattern NameHomerSignificance
motif8.motif1.49045e-08
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00023757400000000003
metacluster_1/pattern_110.00811986
Pattern NameHomerSignificance
motif3.motif0.000885308
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00541096
Pattern NameHomerSignificance
motif2.motif0.000487135
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00376291
Pattern NameHomerSignificance
motif2.motif0.000757383
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0202269
metacluster_1/pattern_75.79153e-07
Pattern NameHomerSignificance
motif2.motif0.0261444
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.027097900000000005
Pattern NameHomerSignificance
motif2.motif0.00578779
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0236425
metacluster_1/pattern_70.0177266
Pattern NameHomerSignificance
motif2.motif0.032785699999999994
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0198924
Pattern NameHomerSignificance
motif2.motif0.0020413000000000002
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00040177699999999997
Pattern NameHomerSignificance
motif3.motif0.0027416
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00031786900000000003
Pattern NameHomerSignificance
motif3.motif0.00874348
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_108.11808e-14
Pattern NameHomerSignificance
motif5.motif0.000153442
Tcf4
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00342266
Pattern NameHomerSignificance
motif7.motif0.0585529
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0292279
Pattern NameHomerSignificance
motif2.motif0.0175225
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00274455
Pattern NameHomerSignificance
motif2.motif0.0020413000000000002
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00621544
Pattern NameHomerSignificance
motif10.motif0.0173933
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0108498
metacluster_1/pattern_80.000142318
Pattern NameHomerSignificance
motif7.motif0.0265288
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0545442
metacluster_1/pattern_110.00705968
Pattern NameHomerSignificance
motif3.motif0.041016000000000004
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_01.6984300000000002e-07
metacluster_1/pattern_20.0334749
Pattern NameHomerSignificance
motif1.motif0.000170433
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00618203
Pattern NameHomerSignificance
motif2.motif0.000454275
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00150557
Pattern NameHomerSignificance
motif2.motif0.0424899
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00275033
metacluster_1/pattern_110.00145126
Pattern NameHomerSignificance
motif3.motif0.026402099999999994
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00541096
Pattern NameHomerSignificance
motif2.motif0.000454275
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00521417
Pattern NameHomerSignificance
motif2.motif0.000454275
Tcf12
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0172262
Pattern NameHomerSignificance
motif7.motif0.0585529
Unique TF-MoDISco TFs: #89
TF NameModiscoHomer
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0336632
Absent
Myod1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.013581799999999998
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0114222
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_72.3498e-15
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0201952
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0010911
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0138658
Absent
Nhlh2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0170666
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.056124
metacluster_1/pattern_130.000763636
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0203212
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.027562
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_40.002522
Absent
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0264022
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0457275
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.044083
metacluster_1/pattern_130.00276107
Absent
Hes7
Pattern NameModiscoSignificance
metacluster_1/pattern_110.031281
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_73.86165e-05
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.015142099999999999
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_73.86165e-05
Absent
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0524587
Absent
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029555099999999997
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00764738
metacluster_1/pattern_130.023316
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0439444
Absent
Meis2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0337202
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.026796299999999995
metacluster_1/pattern_130.03157
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00771041
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_144.77914e-08
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00266436
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_120.056124
metacluster_1/pattern_130.027562
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.010110899999999999
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00185733
metacluster_1/pattern_130.057020600000000005
Absent
Figla
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0521827
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_153.02846e-06
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00147337
Absent
Ptf1a
Pattern NameModiscoSignificance
metacluster_1/pattern_20.05613390000000001
metacluster_1/pattern_30.034707800000000004
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.039521
metacluster_1/pattern_130.000851192
Absent
Tfap2c
Pattern NameModiscoSignificance
metacluster_1/pattern_20.012787799999999998
Absent
Ascl1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.010946
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0250972
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00185733
metacluster_1/pattern_130.03157
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00663835
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00641657
Absent
Rest
Pattern NameModiscoSignificance
metacluster_1/pattern_171.3421099999999999e-13
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_130.032253
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00317992
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00162291
Absent
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_83.81298e-07
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_24.5932299999999994e-05
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000156618
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00522253
metacluster_1/pattern_120.00483844
metacluster_1/pattern_130.054269000000000005
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0270756
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000409749
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00015209
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_75.56236e-06
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0217022
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00298629
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0214558
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0203212
metacluster_1/pattern_130.0349701
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00155753
Absent
Meis3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0337202
Absent
Ascl2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00430314
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0014314
Absent
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00827321
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0584581
metacluster_1/pattern_120.00406913
Absent
Bhlha15
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0337202
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0268731
metacluster_1/pattern_130.00036275099999999997
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00311226
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0297029
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000403269
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00928325
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0201697
metacluster_1/pattern_130.029016900000000005
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_153.02846e-06
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00588852
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_130.032253
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0138773
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00283144
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000551344
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0110242
Absent
Hes5
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029129900000000004
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0006409230000000001
Absent
Pknox2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029129900000000004
Absent
Hey2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.041562
Absent
Nhlh1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.034707800000000004
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0312873
metacluster_1/pattern_130.0250894
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_29.84279e-05
Absent
Myf5
Pattern NameModiscoSignificance
metacluster_1/pattern_30.029129900000000004
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_143.49476e-11
Absent
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0236425
Absent
Snai2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0008074530000000001
Absent
Unique Homer TFs: #7
TF NameModiscoHomer
SpdefAbsent
Pattern NameHomerSignificance
motif2.motif0.00966366
Zic3Absent
Pattern NameHomerSignificance
motif1.motif0.055311900000000004
Zbtb1Absent
Pattern NameHomerSignificance
motif3.motif0.026122500000000003
Zic2Absent
Pattern NameHomerSignificance
motif1.motif0.0530831
E2f6Absent
Pattern NameHomerSignificance
motif3.motif0.05183189999999999
Zbtb33Absent
Pattern NameHomerSignificance
motif12.motif0.0031165
E2f7Absent
Pattern NameHomerSignificance
motif3.motif0.013942500000000002