# Parameters
data_name = "gamma_delta_TCR_MCR;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_78-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_78-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:58:23,562 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	gamma delta TCR Marco
Cell Group	T cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	117583	83548	11.7284	48958645	10651964	0.2177	8073859	0.165	17383340	0.3552

Modelling Metadata

Metric	Value
auPRC	0.6226
Calibrated Recall at 50% FDR	0.195
Number of Positive Examples in Test Data	99508
Number of Negative Examples in Test Data	7971343
Imbalance Ratio in Test Data	0.0123
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #22

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 6326 SequenceContrib ScoresHyp_Contrib Scores	Spib, Spi1, Irf8, Irf4, Etv2, Ets1, Spic, Etv4, Erg, Etv6, Ehf, Elf3, Fli1, Etv3, Gabpa, Elk1, XP_911724.4, Elf1, Elf4, Elk4, Elf2, Elk3, Prdm1, Irf3, Etv1, Etv5, Elf5, Irf2, Irf1, Fev, Spdef
metacluster_1/pattern_1 # seqlets: 5673 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 2863 SequenceContrib ScoresHyp_Contrib Scores	Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Klf4, Klf1, Klf8, Klf12, Egr1, Zbtb17, Egr2, E2f1, Klf5, Zfp281, Sp5, Zfx, Zfp740, Zbtb1
metacluster_1/pattern_3 # seqlets: 1898 SequenceContrib ScoresHyp_Contrib Scores	Stat2, Stat1, Irf7, Irf9, Zscan10, Irf5
metacluster_1/pattern_4 # seqlets: 1174 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_5 # seqlets: 981 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_6 # seqlets: 949 SequenceContrib ScoresHyp_Contrib Scores	Creb1, Creb5, Atf7, Jdp2, Atf2, Atf1, Crem, Jun, Nfil3, Mafb, Tef, Rxrb, Dbp, Atf3, Fosl1, Hlf, Gmeb2, Cebpb
metacluster_1/pattern_7 # seqlets: 812 SequenceContrib ScoresHyp_Contrib Scores	Fosl2, Fos, Jund, Fosb, Junb, Batf, Bach2, Nfe2, Nfe2l2, Bach1, Mafa, Mafk
metacluster_1/pattern_8 # seqlets: 780 SequenceContrib ScoresHyp_Contrib Scores	Usf1, Usf2, Tfec, Tfeb, Arntl, Mitf, Srebf1, Tfe3, Bhlhe40, Clock, Mlx, Arnt, Npas2, Srebf2, Creb3l2, Tcfl5, Bhlhe41, Xbp1, Mlxip, Max, Mycn
metacluster_1/pattern_9 # seqlets: 611 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_10 # seqlets: 581 SequenceContrib ScoresHyp_Contrib Scores	Nfkb2, Relb, Rela, Nfkb1, Rel
metacluster_1/pattern_11 # seqlets: 561 SequenceContrib ScoresHyp_Contrib Scores	Pou2f2
metacluster_1/pattern_12 # seqlets: 521 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Runx3, Cbfb
metacluster_1/pattern_13 # seqlets: 490 SequenceContrib ScoresHyp_Contrib Scores	Rfx1, Rfx2, Rfx3, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_14 # seqlets: 462 SequenceContrib ScoresHyp_Contrib Scores	Mef2a, Mef2d, Mef2c
metacluster_1/pattern_15 # seqlets: 423 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfp42, Wt1, Maz
metacluster_1/pattern_16 # seqlets: 362 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_17 # seqlets: 342 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_18 # seqlets: 174 SequenceContrib ScoresHyp_Contrib Scores	Ets2
metacluster_1/pattern_19 # seqlets: 102 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33
metacluster_1/pattern_20 # seqlets: 84 SequenceContrib ScoresHyp_Contrib Scores	Nfia, Nfib, Nfic
metacluster_1/pattern_21 # seqlets: 50 SequenceContrib ScoresHyp_Contrib Scores

Click here for Motifs by TF-MoDISco: #150

TF Name	Pattern(s)
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 9.08305e-06 metacluster_1/pattern_3 2.46224e-07 metacluster_1/pattern_16 0.00250343
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00126161 metacluster_1/pattern_3 0.00539696 metacluster_1/pattern_16 0.053769399999999995 metacluster_1/pattern_18 0.051934
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000158701 metacluster_1/pattern_3 2.14873e-13 metacluster_1/pattern_16 0.00272014
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00017209400000000002 metacluster_1/pattern_3 0.00831008 metacluster_1/pattern_16 0.00250343
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000180935 metacluster_1/pattern_18 0.0149906
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00157019 metacluster_1/pattern_17 0.049650099999999996 metacluster_1/pattern_18 0.00769588
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177552 metacluster_1/pattern_16 0.0127444
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0055528
Erg	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00163863 metacluster_1/pattern_18 0.033368300000000004
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177518 metacluster_1/pattern_18 0.033368300000000004
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00696855 metacluster_1/pattern_18 0.054356299999999996
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0141644 metacluster_1/pattern_18 0.033368300000000004
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00955277 metacluster_1/pattern_18 0.0234636
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00163863
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_0 0.035590199999999995
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00452947
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177518
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177552 metacluster_1/pattern_16 0.055544500000000004
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00182892
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00470721 metacluster_1/pattern_18 0.0495696
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0135311 metacluster_1/pattern_18 0.0234636
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00452947
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00450814 metacluster_1/pattern_3 0.00545729 metacluster_1/pattern_16 0.053769399999999995
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00464632 metacluster_1/pattern_3 0.0575931
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00567946
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00518837
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0114154 metacluster_1/pattern_3 0.028300099999999998 metacluster_1/pattern_18 0.033368300000000004
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00734031 metacluster_1/pattern_3 0.0086895
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00969216 metacluster_1/pattern_3 1.42888e-06
Fev	Pattern Name Modisco Significance metacluster_1/pattern_0 0.017372 metacluster_1/pattern_18 0.059463999999999996
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_0 0.028719099999999997
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 6.393640000000001e-16
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 6.42298e-08
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.001401
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.5116999999999999e-06 metacluster_1/pattern_15 4.06519e-05 metacluster_1/pattern_19 0.00438438
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.08016e-05 metacluster_1/pattern_15 0.000297363
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.2028599999999999e-05 metacluster_1/pattern_15 0.024909200000000003
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000359961 metacluster_1/pattern_15 0.000297363
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00035315300000000004
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000546747
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0007187560000000001
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.016128200000000002
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.053586
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00134349
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0157846
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.006732899999999999 metacluster_1/pattern_15 0.014142400000000001
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0120214
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0247704
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0247704
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0247704
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0353746 metacluster_1/pattern_4 0.036204 metacluster_1/pattern_15 0.00158391 metacluster_1/pattern_19 0.0136021
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0007995639999999999
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0009326289999999999
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00138911
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00539696
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0148665
Irf5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0508089
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_4 3.91123e-07
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_5 1.61959e-13
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_5 1.62405e-12
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_5 3.7584e-11
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_5 7.897790000000001e-07
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_5 4.1705300000000005e-06
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000539847
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_6 1.93317e-05
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000295727
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00154925 metacluster_1/pattern_7 2.42886e-05
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000539847
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.049321300000000005 metacluster_1/pattern_8 0.0116694
Crem	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00156291
Jun	Pattern Name Modisco Significance metacluster_1/pattern_6 0.033177099999999994 metacluster_1/pattern_7 0.027451299999999998
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00972242
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0138101 metacluster_1/pattern_7 0.055788599999999994
Tef	Pattern Name Modisco Significance metacluster_1/pattern_6 0.017749099999999997
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.026239699999999998
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0390439 metacluster_1/pattern_8 0.0456242
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0596959 metacluster_1/pattern_7 7.352230000000001e-06
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0387516 metacluster_1/pattern_7 0.0324821
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0452124 metacluster_1/pattern_8 0.0456242
Gmeb2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.055774199999999996
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.055774199999999996
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_7 6.20177e-06
Fos	Pattern Name Modisco Significance metacluster_1/pattern_7 4.44653e-06
Jund	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00304517
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_7 4.44653e-06
Junb	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0164165
Batf	Pattern Name Modisco Significance metacluster_1/pattern_7 0.015037299999999998
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00389444
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.011713
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.012682200000000001
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.015037299999999998
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0174795
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0376151
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00263259
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00267303
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00230658
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00110425
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00498527
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00143593
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00263259
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00232016
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00742737
Clock	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0345843
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0206764
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_8 0.038991399999999996
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0025015999999999997
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00364114
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.050451300000000004
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00536647
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0156641
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.043600599999999996
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_8 0.052986
Max	Pattern Name Modisco Significance metacluster_1/pattern_8 0.055923900000000006
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_8 0.057380099999999996
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_9 1.09656e-20
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_9 1.4385e-20
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_9 6.577280000000001e-14
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_10 3.71748e-08
Relb	Pattern Name Modisco Significance metacluster_1/pattern_10 3.21736e-06
Rela	Pattern Name Modisco Significance metacluster_1/pattern_10 7.388409999999999e-05
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_10 1.1853900000000002e-05
Rel	Pattern Name Modisco Significance metacluster_1/pattern_10 0.035961099999999996
Pou2f2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00652377
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00273493
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_12 0.012804300000000001
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00717786
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00900193
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_13 3.17814e-09 metacluster_1/pattern_15 0.024693299999999998
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_13 2.24662e-07
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0159224
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_13 6.0595200000000006e-05
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00708303
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0106024
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00011794899999999999
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_14 2.0650300000000003e-09
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_14 2.0650300000000003e-09
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_15 4.92245e-06 metacluster_1/pattern_18 0.059463999999999996
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_15 1.3744000000000001e-05
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0182067
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.025687900000000003
Maz	Pattern Name Modisco Significance metacluster_1/pattern_15 0.045782199999999995
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_18 0.058164999999999994
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_19 9.66765e-05
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_20 0.000222263
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_20 0.00143222
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_20 0.054945600000000004

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #99

TF Name	Modisco	Homer
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_7 6.20177e-06	Pattern Name Homer Significance motif4.motif 0.0473944 motif19.motif 0.0131554
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00017209400000000002 metacluster_1/pattern_3 0.00831008 metacluster_1/pattern_16 0.00250343	Pattern Name Homer Significance motif2.motif 8.85394e-05
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0120214	Pattern Name Homer Significance motif3.motif 0.0067393
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.043600599999999996	Pattern Name Homer Significance motif4.motif 0.0352301
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.2028599999999999e-05 metacluster_1/pattern_15 0.024909200000000003	Pattern Name Homer Significance motif3.motif 0.00037448099999999997
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631	Pattern Name Homer Significance motif3.motif 0.047835199999999994
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000180935 metacluster_1/pattern_18 0.0149906	Pattern Name Homer Significance motif2.motif 8.85394e-05
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.053586	Pattern Name Homer Significance motif3.motif 0.047835199999999994
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000295727	Pattern Name Homer Significance motif4.motif 0.053740699999999995
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000539847	Pattern Name Homer Significance motif4.motif 0.0352301
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_15 4.92245e-06 metacluster_1/pattern_18 0.059463999999999996	Pattern Name Homer Significance motif13.motif 0.00139011
Batf	Pattern Name Modisco Significance metacluster_1/pattern_7 0.015037299999999998	Pattern Name Homer Significance motif19.motif 0.0131554
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00955277 metacluster_1/pattern_18 0.0234636	Pattern Name Homer Significance motif2.motif 0.000727963
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.016128200000000002	Pattern Name Homer Significance motif3.motif 0.0223966
Fos	Pattern Name Modisco Significance metacluster_1/pattern_7 4.44653e-06	Pattern Name Homer Significance motif19.motif 0.00895332
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 9.08305e-06 metacluster_1/pattern_3 2.46224e-07 metacluster_1/pattern_16 0.00250343	Pattern Name Homer Significance motif2.motif 1.33623e-05
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631	Pattern Name Homer Significance motif3.motif 0.0429541
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0387516 metacluster_1/pattern_7 0.0324821	Pattern Name Homer Significance motif19.motif 0.0248641
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_5 1.61959e-13	Pattern Name Homer Significance motif10.motif 1.5262e-06
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 6.42298e-08	Pattern Name Homer Significance motif1.motif 0.00269314
Erg	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00163863 metacluster_1/pattern_18 0.033368300000000004	Pattern Name Homer Significance motif2.motif 0.000316952
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177552 metacluster_1/pattern_16 0.0127444	Pattern Name Homer Significance motif2.motif 0.000457063
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000158701 metacluster_1/pattern_3 2.14873e-13 metacluster_1/pattern_16 0.00272014	Pattern Name Homer Significance motif2.motif 8.663840000000001e-05
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0135311 metacluster_1/pattern_18 0.0234636	Pattern Name Homer Significance motif2.motif 0.0127679
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_5 1.62405e-12	Pattern Name Homer Significance motif10.motif 6.05346e-05
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0182067	Pattern Name Homer Significance motif13.motif 0.034224300000000006
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0148665	Pattern Name Homer Significance motif2.motif 0.0567446
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00450814 metacluster_1/pattern_3 0.00545729 metacluster_1/pattern_16 0.053769399999999995	Pattern Name Homer Significance motif2.motif 0.006736799999999999
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00134349	Pattern Name Homer Significance motif3.motif 0.000636809
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0247704	Pattern Name Homer Significance motif3.motif 0.0090058
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.08016e-05 metacluster_1/pattern_15 0.000297363	Pattern Name Homer Significance motif3.motif 8.51022e-05
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_9 1.09656e-20	Pattern Name Homer Significance motif6.motif 1.05815e-05
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.5116999999999999e-06 metacluster_1/pattern_15 4.06519e-05 metacluster_1/pattern_19 0.00438438	Pattern Name Homer Significance motif3.motif 0.000107137
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0114154 metacluster_1/pattern_3 0.028300099999999998 metacluster_1/pattern_18 0.033368300000000004	Pattern Name Homer Significance motif2.motif 0.0141852
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_15 1.3744000000000001e-05	Pattern Name Homer Significance motif13.motif 0.00132813
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00126161 metacluster_1/pattern_3 0.00539696 metacluster_1/pattern_16 0.053769399999999995 metacluster_1/pattern_18 0.051934	Pattern Name Homer Significance motif2.motif 0.000361838
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.001401	Pattern Name Homer Significance motif3.motif 0.00757259
Jund	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00304517	Pattern Name Homer Significance motif19.motif 0.0123439
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00734031 metacluster_1/pattern_3 0.0086895	Pattern Name Homer Significance motif2.motif 0.00986232
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_19 9.66765e-05	Pattern Name Homer Significance motif15.motif 0.00500228
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00470721 metacluster_1/pattern_18 0.0495696	Pattern Name Homer Significance motif2.motif 0.000632216
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00567946	Pattern Name Homer Significance motif2.motif 0.0008441939999999999
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00232016	Pattern Name Homer Significance motif4.motif 0.050858
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_9 1.4385e-20	Pattern Name Homer Significance motif6.motif 1.05815e-05
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00452947	Pattern Name Homer Significance motif2.motif 0.00067428
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177518 metacluster_1/pattern_18 0.033368300000000004	Pattern Name Homer Significance motif2.motif 0.00159339
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00143593	Pattern Name Homer Significance motif4.motif 0.05897380000000001
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_0 0.028719099999999997	Pattern Name Homer Significance motif2.motif 0.0181868
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631	Pattern Name Homer Significance motif3.motif 0.018781700000000002
Junb	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0164165	Pattern Name Homer Significance motif19.motif 0.0276968
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.012682200000000001	Pattern Name Homer Significance motif19.motif 0.0248641
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_5 3.7584e-11	Pattern Name Homer Significance motif10.motif 4.1177700000000004e-05
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0247704	Pattern Name Homer Significance motif3.motif 0.0491372
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00163863	Pattern Name Homer Significance motif2.motif 0.000378598
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0007187560000000001	Pattern Name Homer Significance motif3.motif 0.00037448099999999997
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0157846	Pattern Name Homer Significance motif3.motif 0.0408668
Fev	Pattern Name Modisco Significance metacluster_1/pattern_0 0.017372 metacluster_1/pattern_18 0.059463999999999996	Pattern Name Homer Significance motif2.motif 0.00323928
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00464632 metacluster_1/pattern_3 0.0575931	Pattern Name Homer Significance motif2.motif 0.00649301
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00110425	Pattern Name Homer Significance motif4.motif 0.05737949999999999
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0596959 metacluster_1/pattern_7 7.352230000000001e-06	Pattern Name Homer Significance motif4.motif 0.0446977 motif19.motif 0.010836
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00157019 metacluster_1/pattern_17 0.049650099999999996 metacluster_1/pattern_18 0.00769588	Pattern Name Homer Significance motif2.motif 0.000279433
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_7 4.44653e-06	Pattern Name Homer Significance motif19.motif 0.0106301
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.015037299999999998	Pattern Name Homer Significance motif19.motif 0.00455178
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_0 0.035590199999999995	Pattern Name Homer Significance motif2.motif 0.0065089
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_10 1.1853900000000002e-05	Pattern Name Homer Significance motif12.motif 0.0008853089999999999
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177518	Pattern Name Homer Significance motif2.motif 0.000492625
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_10 3.71748e-08	Pattern Name Homer Significance motif12.motif 0.00044341199999999996
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00969216 metacluster_1/pattern_3 1.42888e-06	Pattern Name Homer Significance motif2.motif 0.012326
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0247704	Pattern Name Homer Significance motif3.motif 0.0391266
Crem	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00156291	Pattern Name Homer Significance motif4.motif 0.0352301
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00035315300000000004	Pattern Name Homer Significance motif3.motif 0.00066999
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00182892	Pattern Name Homer Significance motif2.motif 0.000779535
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 6.393640000000001e-16	Pattern Name Homer Significance motif1.motif 0.00018837700000000002
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_4 3.91123e-07	Pattern Name Homer Significance motif11.motif 0.000124709
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00267303	Pattern Name Homer Significance motif4.motif 0.050858
Jun	Pattern Name Modisco Significance metacluster_1/pattern_6 0.033177099999999994 metacluster_1/pattern_7 0.027451299999999998	Pattern Name Homer Significance motif19.motif 0.0248641
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000539847	Pattern Name Homer Significance motif4.motif 0.0352301
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00518837	Pattern Name Homer Significance motif2.motif 0.000910408
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00696855 metacluster_1/pattern_18 0.054356299999999996	Pattern Name Homer Significance motif2.motif 0.00360916
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.049321300000000005 metacluster_1/pattern_8 0.0116694	Pattern Name Homer Significance motif4.motif 0.0352301
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.006732899999999999 metacluster_1/pattern_15 0.014142400000000001	Pattern Name Homer Significance motif3.motif 0.00293445
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00263259	Pattern Name Homer Significance motif4.motif 0.0352301
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00177552 metacluster_1/pattern_16 0.055544500000000004	Pattern Name Homer Significance motif2.motif 0.000457063
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_6 1.93317e-05	Pattern Name Homer Significance motif4.motif 0.0352301
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000359961 metacluster_1/pattern_15 0.000297363	Pattern Name Homer Significance motif3.motif 0.00301797
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_5 4.1705300000000005e-06	Pattern Name Homer Significance motif10.motif 0.0013880999999999998
Rela	Pattern Name Modisco Significance metacluster_1/pattern_10 7.388409999999999e-05	Pattern Name Homer Significance motif12.motif 0.00216753
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_9 6.577280000000001e-14	Pattern Name Homer Significance motif6.motif 5.93067e-05
Relb	Pattern Name Modisco Significance metacluster_1/pattern_10 3.21736e-06	Pattern Name Homer Significance motif12.motif 0.0013792
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00154925 metacluster_1/pattern_7 2.42886e-05	Pattern Name Homer Significance motif4.motif 0.0514769 motif19.motif 0.00949763
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00498527	Pattern Name Homer Significance motif4.motif 0.05737949999999999
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.050451300000000004	Pattern Name Homer Significance motif4.motif 0.052503999999999995
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000546747	Pattern Name Homer Significance motif3.motif 0.00182208
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00389444	Pattern Name Homer Significance motif19.motif 0.0141781
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_5 7.897790000000001e-07	Pattern Name Homer Significance motif10.motif 0.0029828000000000003
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00452947	Pattern Name Homer Significance motif2.motif 0.000888494
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0141644 metacluster_1/pattern_18 0.033368300000000004	Pattern Name Homer Significance motif2.motif 0.00774333
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.011713	Pattern Name Homer Significance motif19.motif 0.0248641
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0055528	Pattern Name Homer Significance motif2.motif 0.000727963

Unique TF-MoDISco TFs: #51

TF Name	Modisco	Homer
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00011794899999999999	Absent
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_18 0.058164999999999994	Absent
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0452124 metacluster_1/pattern_8 0.0456242	Absent
Maz	Pattern Name Modisco Significance metacluster_1/pattern_15 0.045782199999999995	Absent
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_20 0.00143222	Absent
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_8 0.038991399999999996	Absent
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.055774199999999996	Absent
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00539696	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0159224	Absent
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00972242	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_13 3.17814e-09 metacluster_1/pattern_15 0.024693299999999998	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0353746 metacluster_1/pattern_4 0.036204 metacluster_1/pattern_15 0.00158391 metacluster_1/pattern_19 0.0136021	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00708303	Absent
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00138911	Absent
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_8 0.057380099999999996	Absent
Gmeb2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.055774199999999996	Absent
Rel	Pattern Name Modisco Significance metacluster_1/pattern_10 0.035961099999999996	Absent
Irf5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0508089	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00536647	Absent
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_12 0.012804300000000001	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00263259	Absent
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0174795	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0025015999999999997	Absent
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0007995639999999999	Absent
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00717786	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0106024	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.025687900000000003	Absent
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.026239699999999998	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_13 2.24662e-07	Absent
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0009326289999999999	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_13 6.0595200000000006e-05	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_20 0.000222263	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0156641	Absent
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00900193	Absent
Max	Pattern Name Modisco Significance metacluster_1/pattern_8 0.055923900000000006	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0206764	Absent
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0138101 metacluster_1/pattern_7 0.055788599999999994	Absent
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_8 0.052986	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00742737	Absent
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_14 2.0650300000000003e-09	Absent
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_20 0.054945600000000004	Absent
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_14 2.0650300000000003e-09	Absent
Tef	Pattern Name Modisco Significance metacluster_1/pattern_6 0.017749099999999997	Absent
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0495631	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00364114	Absent
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0390439 metacluster_1/pattern_8 0.0456242	Absent
Pou2f2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00652377	Absent
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0376151	Absent
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00273493	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0345843	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00230658	Absent

Unique Homer TFs: #5

TF Name	Modisco	Homer
Rarb	Absent	Pattern Name Homer Significance motif4.motif 0.052448400000000006
E2f7	Absent	Pattern Name Homer Significance motif3.motif 0.010631
Klf15	Absent	Pattern Name Homer Significance motif3.motif 0.00652761
Hinfp	Absent	Pattern Name Homer Significance motif16.motif 0.00139199
E2f6	Absent	Pattern Name Homer Significance motif3.motif 0.0253386