In [1]:
# Parameters
data_name = "aB_CD40+IL4;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_17-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_17-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:44:21,508 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeaB aCD40+IL4
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1625734314510.67358229649369883130.084968722360.0835262529200.3191
    Modelling Metadata
    MetricValue
    auPRC0.7064
    Calibrated Recall at 50% FDR0.157
    Number of Positive Examples in Test Data43501
    Number of Negative Examples in Test Data8027350
    Imbalance Ratio in Test Data0.0054
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #19
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5226 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4689 SequenceContrib ScoresHyp_Contrib Scores
Etv6, Gabpa, Elk1, Ets1, Fli1, Erg, Spi1, Spib, Etv3, Elk3,

XP_911724.4, Etv2, Elk4, Spic, Elf1, Etv5, Etv4, Elf4, Etv1, Irf4, Irf8,

Elf2, Ehf, Elf3, Elf5, Fev, Spdef, Prdm1, Irf2, Irf3, Irf1
metacluster_1/pattern_2 # seqlets: 3848 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp3, Klf3, Sp1, Sp4, Egr1, Klf4, Zbtb17, Klf5, E2f4,

Sp5, Klf7, Klf6, Zfp281, Klf8, Wt1, Klf12, Egr2, Maz, Klf1, E2f1,

Klf15, Srebf2, Egr3, Zfp740
metacluster_1/pattern_3 # seqlets: 2160 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_4 # seqlets: 1793 SequenceContrib ScoresHyp_Contrib Scores
Nrf1, Zfx
metacluster_1/pattern_5 # seqlets: 1330 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf1, Atf7, Jdp2, Atf2, Crem, Creb5, Usf2, Atf3, Jun,

Rxrb
metacluster_1/pattern_6 # seqlets: 1259 SequenceContrib ScoresHyp_Contrib Scores
Stat2, Irf7, Stat1, Irf9, Zscan10
metacluster_1/pattern_7 # seqlets: 1169 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Rfx1, Zfp42, Mxi1
metacluster_1/pattern_8 # seqlets: 977 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_9 # seqlets: 606 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfe3, Tfeb, Arntl, Tfec, Mitf, Bhlhe40, Srebf1, Clock, Arnt,

Mlx, Npas2, Tcfl5, Creb3l2, Max, Bhlhe41, Mycn, Myc, Hlf, Dbp, Xbp1,

Mlxip
metacluster_1/pattern_10 # seqlets: 392 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_1/pattern_11 # seqlets: 276 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6, Sox2, Pou5f1
metacluster_1/pattern_12 # seqlets: 248 SequenceContrib ScoresHyp_Contrib Scores
Nfkb1, Rela, Nfkb2, Relb, Rel
metacluster_1/pattern_13 # seqlets: 194 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_14 # seqlets: 184 SequenceContrib ScoresHyp_Contrib Scores
Junb, Fosb, Fosl2, Jund, Batf, Fos, Fosl1, Mafa, Bach2, Pknox1,

Bach1
metacluster_1/pattern_15 # seqlets: 116 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 103 SequenceContrib ScoresHyp_Contrib Scores
Mef2a, Mef2c, Mef2d
metacluster_1/pattern_17 # seqlets: 42 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_18 # seqlets: 39 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #139
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_02.40311e-12
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_02.65273e-08
metacluster_1/pattern_20.034350099999999995
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00152309
metacluster_1/pattern_150.0351819
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0027385
metacluster_1/pattern_50.00499642
metacluster_1/pattern_150.017577000000000002
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000169817
metacluster_1/pattern_50.0531563
metacluster_1/pattern_150.029612799999999998
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_13.82697e-05
metacluster_1/pattern_150.017577000000000002
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000478434
metacluster_1/pattern_150.0351819
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_14.15897e-05
metacluster_1/pattern_150.0158527
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000516936
metacluster_1/pattern_60.00427006
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_14.10144e-05
metacluster_1/pattern_68.428610000000001e-07
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_14.10144e-05
metacluster_1/pattern_150.0443469
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00015768
metacluster_1/pattern_150.0549332
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_15.13781e-05
metacluster_1/pattern_150.0418341
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_15.299649999999999e-05
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00015488
metacluster_1/pattern_150.0277399
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00037304300000000004
metacluster_1/pattern_60.0393174
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_17.78666e-05
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_17.78666e-05
metacluster_1/pattern_150.00773197
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00015768
metacluster_1/pattern_150.0158527
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000155458
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019638200000000002
metacluster_1/pattern_150.00480729
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000169817
metacluster_1/pattern_60.0188447
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000179863
metacluster_1/pattern_64.04119e-14
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016572999999999997
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000827701
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0027651999999999998
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0177565
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00268429
metacluster_1/pattern_50.051651800000000005
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00379377
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00758888
metacluster_1/pattern_60.004961999999999999
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00811118
metacluster_1/pattern_60.0180981
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0140589
metacluster_1/pattern_60.00057016
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015434999999999999
metacluster_1/pattern_61.57279e-05
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_28.311339999999999e-10
metacluster_1/pattern_72.7028200000000003e-05
metacluster_1/pattern_130.000587539
metacluster_1/pattern_154.9605200000000004e-05
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_25.53702e-09
metacluster_1/pattern_70.000709804
metacluster_1/pattern_130.00202388
metacluster_1/pattern_150.00390248
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_28.69774e-08
metacluster_1/pattern_70.0420093
metacluster_1/pattern_150.00480729
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000318355
metacluster_1/pattern_70.000123582
metacluster_1/pattern_130.00336215
metacluster_1/pattern_150.00516235
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00130524
metacluster_1/pattern_150.0277399
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.026023900000000003
metacluster_1/pattern_150.013227500000000001
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00082122
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000176537
metacluster_1/pattern_70.00760607
metacluster_1/pattern_150.00970802
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000239909
metacluster_1/pattern_150.0196158
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000318355
metacluster_1/pattern_150.00135789
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00040935699999999995
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000601858
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008136589999999999
metacluster_1/pattern_150.013881600000000001
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00164751
metacluster_1/pattern_150.0326632
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00110078
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00110078
metacluster_1/pattern_70.022253
metacluster_1/pattern_150.026034699999999997
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00111542
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0515842
metacluster_1/pattern_70.05140309999999999
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00345725
metacluster_1/pattern_70.0515692
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0201389
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0185009
metacluster_1/pattern_150.034556699999999996
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0185009
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0515842
metacluster_1/pattern_90.00358743
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0519865
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0519865
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_31.4381799999999998e-10
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_34.13687e-06
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_34.13687e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_34.13687e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000109299
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.41226e-07
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_40.054735900000000004
metacluster_1/pattern_70.00409169
metacluster_1/pattern_130.0506105
metacluster_1/pattern_150.0158527
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0107038
metacluster_1/pattern_90.045431099999999995
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0130609
metacluster_1/pattern_90.015100899999999999
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00132944
metacluster_1/pattern_90.0253937
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00493017
metacluster_1/pattern_90.0582133
metacluster_1/pattern_140.00216332
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00230626
metacluster_1/pattern_90.0378904
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_50.051651800000000005
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00265497
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0039742
metacluster_1/pattern_90.00543378
metacluster_1/pattern_130.014044599999999999
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0196472
metacluster_1/pattern_140.000343418
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_50.022364
metacluster_1/pattern_140.000343418
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_50.05610980000000001
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0039759
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0039759
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00855548
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.010145200000000002
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_60.013276900000000001
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_72.09604e-06
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_72.09604e-06
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00720721
metacluster_1/pattern_112.03103e-12
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00722428
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0528193
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_82.88915e-22
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_82.88915e-22
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_89.870369999999999e-14
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00634466
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00226344
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000547858
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00628383
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00236434
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00121823
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00765618
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0276245
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_90.025062400000000002
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0323623
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0112072
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00368695
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00785184
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.023372
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0128236
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_90.015100899999999999
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0163887
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0269789
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.023615599999999997
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0378904
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.048994199999999995
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05213480000000001
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00610619
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000862647
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.025907
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_117.87594e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000428331
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00189436
Sox2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0524281
Pou5f1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.053213300000000005
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_121.25949e-05
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000203584
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000203584
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000636936
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_120.010528000000000001
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_132.01862e-05
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000343418
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000394692
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000641143
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0339865
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00062785
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00120672
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00128835
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0285203
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0339865
Pknox1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0355495
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.056443499999999994
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_169.63438e-05
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_166.53543e-09
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_167.40745e-09
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #65
TF NameModiscoHomer
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000516936
metacluster_1/pattern_60.00427006
Pattern NameHomerSignificance
motif3.motif0.029303899999999997
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_31.4381799999999998e-10
Pattern NameHomerSignificance
motif4.motif2.97058e-09
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_34.13687e-06
Pattern NameHomerSignificance
motif4.motif9.274250000000001e-07
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00111542
Pattern NameHomerSignificance
motif2.motif0.0230871
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019638200000000002
metacluster_1/pattern_150.00480729
Pattern NameHomerSignificance
motif3.motif7.04633e-05
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0177565
Pattern NameHomerSignificance
motif3.motif0.00169266
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_15.13781e-05
metacluster_1/pattern_150.0418341
Pattern NameHomerSignificance
motif3.motif1.80878e-05
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_25.53702e-09
metacluster_1/pattern_70.000709804
metacluster_1/pattern_130.00202388
metacluster_1/pattern_150.00390248
Pattern NameHomerSignificance
motif2.motif0.000244093
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00152309
metacluster_1/pattern_150.0351819
Pattern NameHomerSignificance
motif3.motif0.00339942
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00015488
metacluster_1/pattern_150.0277399
Pattern NameHomerSignificance
motif3.motif0.00034561199999999997
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00758888
metacluster_1/pattern_60.004961999999999999
Pattern NameHomerSignificance
motif14.motif0.00953308
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_14.15897e-05
metacluster_1/pattern_150.0158527
Pattern NameHomerSignificance
motif3.motif0.0005593169999999999
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_15.299649999999999e-05
Pattern NameHomerSignificance
motif3.motif0.00177163
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000478434
metacluster_1/pattern_150.0351819
Pattern NameHomerSignificance
motif3.motif0.00108481
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_28.69774e-08
metacluster_1/pattern_70.0420093
metacluster_1/pattern_150.00480729
Pattern NameHomerSignificance
motif2.motif0.000447295
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_14.10144e-05
metacluster_1/pattern_68.428610000000001e-07
Pattern NameHomerSignificance
motif3.motif0.0178433
motif14.motif0.014954499999999999
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016572999999999997
Pattern NameHomerSignificance
motif3.motif0.0188468
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_34.13687e-06
Pattern NameHomerSignificance
motif4.motif5.1664499999999995e-06
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00110078
Pattern NameHomerSignificance
motif2.motif0.0009319780000000001
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000169817
metacluster_1/pattern_60.0188447
Pattern NameHomerSignificance
motif3.motif0.040966
motif14.motif0.014954499999999999
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000179863
metacluster_1/pattern_64.04119e-14
Pattern NameHomerSignificance
motif3.motif0.0400785
motif14.motif0.000791987
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_28.311339999999999e-10
metacluster_1/pattern_72.7028200000000003e-05
metacluster_1/pattern_130.000587539
metacluster_1/pattern_154.9605200000000004e-05
Pattern NameHomerSignificance
motif2.motif0.000244093
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0201389
Pattern NameHomerSignificance
motif2.motif0.0230871
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_132.01862e-05
Pattern NameHomerSignificance
motif10.motif0.000292917
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0027385
metacluster_1/pattern_50.00499642
metacluster_1/pattern_150.017577000000000002
Pattern NameHomerSignificance
motif3.motif0.00433741
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_72.09604e-06
Pattern NameHomerSignificance
motif12.motif0.0546038
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_17.78666e-05
metacluster_1/pattern_150.00773197
Pattern NameHomerSignificance
motif3.motif8.82115e-07
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_02.65273e-08
metacluster_1/pattern_20.034350099999999995
Pattern NameHomerSignificance
motif1.motif0.000119484
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_72.09604e-06
Pattern NameHomerSignificance
motif12.motif0.0546038
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00268429
metacluster_1/pattern_50.051651800000000005
Pattern NameHomerSignificance
motif3.motif0.00877863
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008136589999999999
metacluster_1/pattern_150.013881600000000001
Pattern NameHomerSignificance
motif2.motif0.00523165
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_82.88915e-22
Pattern NameHomerSignificance
motif5.motif7.1554e-07
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00811118
metacluster_1/pattern_60.0180981
Pattern NameHomerSignificance
motif14.motif0.000791987
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00015768
metacluster_1/pattern_150.0549332
Pattern NameHomerSignificance
motif3.motif0.000349275
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000155458
Pattern NameHomerSignificance
motif3.motif8.88335e-05
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000318355
metacluster_1/pattern_150.00135789
Pattern NameHomerSignificance
motif2.motif0.00101501
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.41226e-07
Pattern NameHomerSignificance
motif6.motif1.7425000000000002e-07
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00082122
Pattern NameHomerSignificance
motif2.motif0.0463626
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00379377
Pattern NameHomerSignificance
motif3.motif0.00742117
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_34.13687e-06
Pattern NameHomerSignificance
motif4.motif5.19159e-07
Pou5f1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.053213300000000005
Pattern NameHomerSignificance
motif20.motif0.0313994
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000601858
Pattern NameHomerSignificance
motif2.motif0.000447295
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00130524
metacluster_1/pattern_150.0277399
Pattern NameHomerSignificance
motif2.motif0.0230871
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0039759
Pattern NameHomerSignificance
motif14.motif0.014954499999999999
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_40.054735900000000004
metacluster_1/pattern_70.00409169
metacluster_1/pattern_130.0506105
metacluster_1/pattern_150.0158527
Pattern NameHomerSignificance
motif2.motif0.0355079
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000176537
metacluster_1/pattern_70.00760607
metacluster_1/pattern_150.00970802
Pattern NameHomerSignificance
motif2.motif0.048258300000000004
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015434999999999999
metacluster_1/pattern_61.57279e-05
Pattern NameHomerSignificance
motif14.motif0.00106295
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.026023900000000003
metacluster_1/pattern_150.013227500000000001
Pattern NameHomerSignificance
motif2.motif0.0158673
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_17.78666e-05
Pattern NameHomerSignificance
motif3.motif0.0008496360000000001
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0515842
metacluster_1/pattern_70.05140309999999999
Pattern NameHomerSignificance
motif2.motif0.042462099999999996
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_13.82697e-05
metacluster_1/pattern_150.017577000000000002
Pattern NameHomerSignificance
motif3.motif0.000888278
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000169817
metacluster_1/pattern_50.0531563
metacluster_1/pattern_150.029612799999999998
Pattern NameHomerSignificance
motif3.motif0.000350648
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00037304300000000004
metacluster_1/pattern_60.0393174
Pattern NameHomerSignificance
motif3.motif0.00322562
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0185009
metacluster_1/pattern_150.034556699999999996
Pattern NameHomerSignificance
motif2.motif0.05619640000000001
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_89.870369999999999e-14
Pattern NameHomerSignificance
motif5.motif6.13152e-05
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00015768
metacluster_1/pattern_150.0158527
Pattern NameHomerSignificance
motif3.motif0.00205174
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000239909
metacluster_1/pattern_150.0196158
Pattern NameHomerSignificance
motif2.motif0.0161822
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_02.40311e-12
Pattern NameHomerSignificance
motif1.motif9.26843e-07
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000318355
metacluster_1/pattern_70.000123582
metacluster_1/pattern_130.00336215
metacluster_1/pattern_150.00516235
Pattern NameHomerSignificance
motif2.motif0.00935395
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000827701
Pattern NameHomerSignificance
motif3.motif0.0181107
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_14.10144e-05
metacluster_1/pattern_150.0443469
Pattern NameHomerSignificance
motif3.motif1.34451e-05
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000109299
Pattern NameHomerSignificance
motif4.motif0.000107267
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_82.88915e-22
Pattern NameHomerSignificance
motif5.motif7.37528e-07
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0027651999999999998
Pattern NameHomerSignificance
motif3.motif0.032913300000000006
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00610619
Pattern NameHomerSignificance
motif20.motif0.016439099999999998
Unique TF-MoDISco TFs: #74
TF NameModiscoHomer
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00132944
metacluster_1/pattern_90.0253937
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.023372
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0128236
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.056443499999999994
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0269789
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00265497
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00765618
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000394692
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0039742
metacluster_1/pattern_90.00543378
metacluster_1/pattern_130.014044599999999999
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0519865
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00164751
metacluster_1/pattern_150.0326632
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0107038
metacluster_1/pattern_90.045431099999999995
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.048994199999999995
Absent
Sox2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0524281
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0112072
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0276245
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0130609
metacluster_1/pattern_90.015100899999999999
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0285203
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.023615599999999997
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00720721
metacluster_1/pattern_112.03103e-12
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_117.87594e-05
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000641143
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00110078
metacluster_1/pattern_70.022253
metacluster_1/pattern_150.026034699999999997
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0515842
metacluster_1/pattern_90.00358743
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00345725
metacluster_1/pattern_70.0515692
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_166.53543e-09
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0339865
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.025907
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00785184
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0196472
metacluster_1/pattern_140.000343418
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00121823
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00230626
metacluster_1/pattern_90.0378904
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_60.013276900000000001
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00368695
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00062785
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00236434
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_90.015100899999999999
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00226344
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_169.63438e-05
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0185009
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0039759
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00628383
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.010145200000000002
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00189436
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0528193
Absent
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_121.25949e-05
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0519865
Absent
Pknox1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0355495
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00128835
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0339865
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00120672
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00493017
metacluster_1/pattern_90.0582133
metacluster_1/pattern_140.00216332
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000428331
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0140589
metacluster_1/pattern_60.00057016
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0163887
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_50.022364
metacluster_1/pattern_140.000343418
Absent
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000203584
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_90.025062400000000002
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00855548
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00634466
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00040935699999999995
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0378904
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0323623
Absent
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000636936
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_50.051651800000000005
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_120.010528000000000001
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05213480000000001
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000343418
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_50.05610980000000001
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000862647
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00722428
Absent
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000203584
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000547858
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_167.40745e-09
Absent
Unique Homer TFs: #5
TF NameModiscoHomer
Zbtb1Absent
Pattern NameHomerSignificance
motif2.motif0.048258300000000004
Zic3Absent
Pattern NameHomerSignificance
motif1.motif0.049511599999999996
Snai1Absent
Pattern NameHomerSignificance
motif1.motif0.0359168
NanogAbsent
Pattern NameHomerSignificance
motif20.motif0.0313994
Zic2Absent
Pattern NameHomerSignificance
motif1.motif0.0431789