# Parameters
data_name = "NIH3T3_FBROBLST;D;GEO"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_201-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_201-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 19:27:14,532 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	fibroblast/NIH-3T3
Cell Group	Cancer or Immortalized cells
Experiment Name	DHS
Experiment Group	GEO

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	178711	131097	9.0924	137641571	29367723	0.2134	13994334	0.1017	57006956	0.4142

Modelling Metadata

Metric	Value
auPRC	0.5795
Calibrated Recall at 50% FDR	0.237
Number of Positive Examples in Test Data	121403
Number of Negative Examples in Test Data	7949448
Imbalance Ratio in Test Data	0.015
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #22

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 6063 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 3747 SequenceContrib ScoresHyp_Contrib Scores	Fosl2, Fosl1, Fos, Batf, Jund, Jun, Atf3, Fosb, Junb, Jdp2, Bach2, Nfe2l2, Nfe2, Mafa, Mafk, Bach1, Mafb, Mafg, Maff, Maf
metacluster_1/pattern_2 # seqlets: 2778 SequenceContrib ScoresHyp_Contrib Scores	Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf7, Klf4, Klf6, Klf1, Klf8, Klf12, Egr1, Egr2, Zbtb17, Klf5, E2f1, Sp5, Zfp281, Egr3, Zfx, Zfp740, Sall4
metacluster_1/pattern_3 # seqlets: 2332 SequenceContrib ScoresHyp_Contrib Scores	Nfib, Nfia, Nfic
metacluster_1/pattern_4 # seqlets: 1312 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1127 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_6 # seqlets: 1107 SequenceContrib ScoresHyp_Contrib Scores	Atf7, Atf2, Creb1, Creb5, Crem, Atf1, Nfil3, Tef, Tfe3, Creb3l2, Hlf
metacluster_1/pattern_7 # seqlets: 1013 SequenceContrib ScoresHyp_Contrib Scores	Cebpb, Cebpa, Cebpd, Cebpg, Cebpe, Dbp, Atf4, Ddit3
metacluster_1/pattern_8 # seqlets: 943 SequenceContrib ScoresHyp_Contrib Scores	Gabpa, Fli1, Ets1, Elf1, Elk4, Erg, Elk1, Etv4, Etv1, Elk3, Etv2, Etv6, Etv5, Etv3, XP_911724.4, Fev, Ehf, Elf4, Elf5, Elf2, Spdef, Elf3, Spi1, Spib
metacluster_1/pattern_9 # seqlets: 854 SequenceContrib ScoresHyp_Contrib Scores	Twist1, Bhlha15, Tcf21, Lhx3, Lhx1, Lhx5, Msc, Olig2, Neurog1, Lmx1b, Bhlhe22
metacluster_1/pattern_10 # seqlets: 745 SequenceContrib ScoresHyp_Contrib Scores	Tead4, Tead1, Tead2
metacluster_1/pattern_11 # seqlets: 596 SequenceContrib ScoresHyp_Contrib Scores	Usf1, Usf2, Tfec, Tfeb, Mitf, Arntl, Srebf1, Bhlhe40, Mlx, Clock, Arnt, Npas2, Srebf2, Tcfl5, Bhlhe41, Xbp1, Mycn, Max, Mlxip, Arnt2
metacluster_1/pattern_12 # seqlets: 594 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Wt1, Zfp42, Maz, Mxi1
metacluster_1/pattern_13 # seqlets: 517 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_14 # seqlets: 332 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Cbfb, Runx3
metacluster_1/pattern_15 # seqlets: 295 SequenceContrib ScoresHyp_Contrib Scores	Mef2d, Mef2a, Mef2c
metacluster_1/pattern_16 # seqlets: 277 SequenceContrib ScoresHyp_Contrib Scores	Irf1, Irf2, Irf7, Irf8, Prdm1, Stat1, Irf9, Irf4, Batf3, Stat2, Irf3
metacluster_1/pattern_17 # seqlets: 259 SequenceContrib ScoresHyp_Contrib Scores	Rfx3, Rfx1, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_18 # seqlets: 196 SequenceContrib ScoresHyp_Contrib Scores	Rest
metacluster_1/pattern_19 # seqlets: 193 SequenceContrib ScoresHyp_Contrib Scores	Six2, Six1, Six4
metacluster_1/pattern_20 # seqlets: 118 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_21 # seqlets: 103 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33

Click here for Motifs by TF-MoDISco: #169

TF Name	Pattern(s)
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 9.044379999999999e-15
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 4.963e-07
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_1 1.2782700000000001e-06 metacluster_1/pattern_6 0.00492911
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0114339 metacluster_1/pattern_6 0.0085685
Fos	Pattern Name Modisco Significance metacluster_1/pattern_1 1.2782700000000001e-06
Batf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0143132
Jund	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00864106
Jun	Pattern Name Modisco Significance metacluster_1/pattern_1 4.02811e-05 metacluster_1/pattern_6 0.0411945
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000105105 metacluster_1/pattern_6 0.00560208
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00012341200000000002
Junb	Pattern Name Modisco Significance metacluster_1/pattern_1 0.030450900000000003
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000224545 metacluster_1/pattern_6 0.000146699
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0007532
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00206537
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00206537
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00206537
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00302712
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00209068
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00555069 metacluster_1/pattern_6 0.00390298
Mafg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00605384
Maff	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00801881
Maf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00966191
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00113504
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 5.083780000000001e-06 metacluster_1/pattern_12 5.0532e-05
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 7.81138e-06 metacluster_1/pattern_12 0.000297378
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 7.81138e-06 metacluster_1/pattern_12 0.0257303
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000362605 metacluster_1/pattern_12 5.0532e-05
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000362605
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000362605
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00621602
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000385378
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0255824
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00056034
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0140916
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.027239299999999998
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.027239299999999998 metacluster_1/pattern_12 0.0371213
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00593862 metacluster_1/pattern_12 0.00892399
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.010173200000000002
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.012310799999999998
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0140916
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.018141499999999998
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_2 0.031292900000000005
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0348251 metacluster_1/pattern_12 0.00195036 metacluster_1/pattern_21 0.0415374
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0413896
Sall4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0449566
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_3 6.350409999999999e-06
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_3 0.000268785
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0030294000000000002
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_4 1.9406900000000002e-14
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_4 1.99607e-11
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_4 5.50498e-11
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_4 5.56317e-07
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_4 3.10103e-06
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_5 8.16204e-09
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_6 4.6358999999999994e-05
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000186519
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0012387000000000001 metacluster_1/pattern_11 0.0594946
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_6 1.8692799999999998e-05
Crem	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00274275
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0168047 metacluster_1/pattern_11 0.0176754
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0109403 metacluster_1/pattern_7 0.0409806
Tef	Pattern Name Modisco Significance metacluster_1/pattern_6 0.021059400000000002 metacluster_1/pattern_7 0.0192787
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0411945 metacluster_1/pattern_11 0.00125508
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0454996 metacluster_1/pattern_11 0.0427149
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0506478 metacluster_1/pattern_7 0.038244 metacluster_1/pattern_11 0.03967380000000001
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00169024
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00179007
Cebpd	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00228823
Cebpg	Pattern Name Modisco Significance metacluster_1/pattern_7 0.007327199999999999
Cebpe	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00349334
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0242154 metacluster_1/pattern_11 0.03967380000000001
Atf4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00888805
Ddit3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00721746
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00052997
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000187818
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000169668
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_8 1.0646900000000001e-05
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000138059
Erg	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000169668
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_8 7.29494e-05
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00545369
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000138059
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000138059
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000356337
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0230484
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000466757
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0004969519999999999
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0005784680000000001
Fev	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000623491
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00483758
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00118387
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0154066
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0551822
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0324298
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0177981
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.029684
Spib	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0551822 metacluster_1/pattern_16 0.00498478
Twist1	Pattern Name Modisco Significance metacluster_1/pattern_9 1.7452300000000002e-23
Bhlha15	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898
Tcf21	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898
Lhx3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898
Lhx1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898
Lhx5	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898
Msc	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898
Olig2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0470778
Neurog1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0401779
Lmx1b	Pattern Name Modisco Significance metacluster_1/pattern_9 0.05548240000000001
Bhlhe22	Pattern Name Modisco Significance metacluster_1/pattern_9 0.05548240000000001
Tead4	Pattern Name Modisco Significance metacluster_1/pattern_10 0.04523219999999999
Tead1	Pattern Name Modisco Significance metacluster_1/pattern_10 0.013194599999999999
Tead2	Pattern Name Modisco Significance metacluster_1/pattern_10 0.0313702
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00295398
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000949153
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00111429
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0009118
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000851898
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00579344
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00218962
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0121457
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_11 0.014529599999999998
Clock	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0589148
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_11 0.03967380000000001
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00201018
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00503428
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00539874
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_11 0.019075400000000003
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0350354
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0514217
Max	Pattern Name Modisco Significance metacluster_1/pattern_11 0.044927499999999995
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_11 0.044927499999999995
Arnt2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0594946
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_12 7.60279e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_12 1.02333e-05
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.012942799999999999
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_12 0.012942799999999999
Maz	Pattern Name Modisco Significance metacluster_1/pattern_12 0.020522400000000003
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.042381999999999996
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_13 2.6195100000000004e-21
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_13 3.42912e-20
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_13 7.9838e-14
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00291677
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.036200699999999995
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_14 0.000993315
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_14 0.010808499999999999
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_15 1.2229600000000001e-14
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_15 0.000186578
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_15 5.732090000000001e-10
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_16 7.91091e-09
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00203461
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000158288
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000158288
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00050263
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000700325
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00149474
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_16 0.036451599999999994
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00203461
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00498478
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00940006
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00209161
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_17 2.73146e-09
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_17 2.65535e-08
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000154865
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00124424
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00171589
Rest	Pattern Name Modisco Significance metacluster_1/pattern_18 1.1984200000000001e-20
Six2	Pattern Name Modisco Significance metacluster_1/pattern_19 3.3898299999999997e-09
Six1	Pattern Name Modisco Significance metacluster_1/pattern_19 2.12279e-08
Six4	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00033983
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_21 2.02439e-05

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #101

TF Name	Modisco	Homer
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0012387000000000001 metacluster_1/pattern_11 0.0594946	Pattern Name Homer Significance motif10.motif 0.0155629
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.012310799999999998	Pattern Name Homer Significance motif3.motif 0.00133876
Atf4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00888805	Pattern Name Homer Significance motif5.motif 0.028654400000000003
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_2 0.031292900000000005	Pattern Name Homer Significance motif3.motif 0.036318
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0242154 metacluster_1/pattern_11 0.03967380000000001	Pattern Name Homer Significance motif5.motif 0.0129018
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0168047 metacluster_1/pattern_11 0.0176754	Pattern Name Homer Significance motif10.motif 0.000242697
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0411945 metacluster_1/pattern_11 0.00125508	Pattern Name Homer Significance motif10.motif 0.0155629
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000224545 metacluster_1/pattern_6 0.000146699	Pattern Name Homer Significance motif2.motif 0.000235779 motif10.motif 0.0151834
Rest	Pattern Name Modisco Significance metacluster_1/pattern_18 1.1984200000000001e-20	Pattern Name Homer Significance motif20.motif 0.000540597
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0004969519999999999	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000362605 metacluster_1/pattern_12 5.0532e-05	Pattern Name Homer Significance motif3.motif 0.000848452
Maff	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00801881	Pattern Name Homer Significance motif2.motif 0.012787
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 7.81138e-06 metacluster_1/pattern_12 0.000297378	Pattern Name Homer Significance motif3.motif 0.000776004
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00621602	Pattern Name Homer Significance motif3.motif 0.00624415
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.027239299999999998	Pattern Name Homer Significance motif3.motif 0.00188214
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000138059	Pattern Name Homer Significance motif14.motif 0.0365855
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00206537	Pattern Name Homer Significance motif2.motif 0.012513600000000001
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0506478 metacluster_1/pattern_7 0.038244 metacluster_1/pattern_11 0.03967380000000001	Pattern Name Homer Significance motif5.motif 0.0139295
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00179007	Pattern Name Homer Significance motif5.motif 0.00331158
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0324298	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 4.963e-07	Pattern Name Homer Significance motif1.motif 0.00113279
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00012341200000000002	Pattern Name Homer Significance motif2.motif 0.00015926799999999998
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_4 5.56317e-07	Pattern Name Homer Significance motif9.motif 0.000364585
Maf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00966191	Pattern Name Homer Significance motif2.motif 0.0240363
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00545369	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000169668	Pattern Name Homer Significance motif14.motif 0.029081799999999998
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00295398	Pattern Name Homer Significance motif10.motif 0.00650049
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_13 3.42912e-20	Pattern Name Homer Significance motif4.motif 5.09206e-08
Erg	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000169668	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00118387	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_14 0.010808499999999999	Pattern Name Homer Significance motif16.motif 0.00115406
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00056034	Pattern Name Homer Significance motif3.motif 1.4222899999999999e-05
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0140916	Pattern Name Homer Significance motif3.motif 0.0434289
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.027239299999999998 metacluster_1/pattern_12 0.0371213	Pattern Name Homer Significance motif3.motif 0.0114038
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000138059	Pattern Name Homer Significance motif14.motif 0.0217899
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 7.81138e-06 metacluster_1/pattern_12 0.0257303	Pattern Name Homer Significance motif3.motif 5.93376e-05
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00291677	Pattern Name Homer Significance motif16.motif 0.00115406
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000187818	Pattern Name Homer Significance motif14.motif 0.019549599999999997
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0005784680000000001	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Batf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0143132	Pattern Name Homer Significance motif2.motif 2.34245e-05
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.036200699999999995	Pattern Name Homer Significance motif16.motif 0.0280217
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_13 7.9838e-14	Pattern Name Homer Significance motif4.motif 1.00527e-05
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_1 1.2782700000000001e-06 metacluster_1/pattern_6 0.00492911	Pattern Name Homer Significance motif2.motif 3.3228700000000004e-07 motif10.motif 0.054643399999999995
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000949153	Pattern Name Homer Significance motif10.motif 0.00650049
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0454996 metacluster_1/pattern_11 0.0427149	Pattern Name Homer Significance motif10.motif 0.05677240000000001
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000466757	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_5 8.16204e-09	Pattern Name Homer Significance motif6.motif 0.00028680400000000004
Fos	Pattern Name Modisco Significance metacluster_1/pattern_1 1.2782700000000001e-06	Pattern Name Homer Significance motif2.motif 3.30311e-07
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00052997	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_12 7.60279e-06	Pattern Name Homer Significance motif17.motif 0.006427199999999999
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_4 3.10103e-06	Pattern Name Homer Significance motif9.motif 0.00041878
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_12 1.02333e-05	Pattern Name Homer Significance motif17.motif 0.0304691
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000356337	Pattern Name Homer Significance motif14.motif 0.0380654
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0255824	Pattern Name Homer Significance motif3.motif 0.028548700000000003
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_6 4.6358999999999994e-05	Pattern Name Homer Significance motif10.motif 0.010281
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_13 2.6195100000000004e-21	Pattern Name Homer Significance motif4.motif 7.83409e-08
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0007532	Pattern Name Homer Significance motif2.motif 0.00338794
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0114339 metacluster_1/pattern_6 0.0085685	Pattern Name Homer Significance motif2.motif 0.0177601
Mafg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00605384	Pattern Name Homer Significance motif2.motif 0.0110146
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00111429	Pattern Name Homer Significance motif10.motif 0.025939799999999996
Junb	Pattern Name Modisco Significance metacluster_1/pattern_1 0.030450900000000003	Pattern Name Homer Significance motif2.motif 0.0328004
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000362605	Pattern Name Homer Significance motif3.motif 0.000302528
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000362605	Pattern Name Homer Significance motif3.motif 6.811310000000001e-06
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0121457	Pattern Name Homer Significance motif10.motif 0.0385265
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000158288	Pattern Name Homer Significance motif14.motif 0.0328978
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00555069 metacluster_1/pattern_6 0.00390298	Pattern Name Homer Significance motif2.motif 0.0177601 motif10.motif 0.044243
Cebpe	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00349334	Pattern Name Homer Significance motif5.motif 0.000555206
Jund	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00864106	Pattern Name Homer Significance motif2.motif 0.0110146
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_4 1.99607e-11	Pattern Name Homer Significance motif9.motif 5.1154400000000004e-06
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000385378	Pattern Name Homer Significance motif3.motif 0.000776004
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_8 7.29494e-05	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_8 1.0646900000000001e-05	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000851898	Pattern Name Homer Significance motif10.motif 0.0387653
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_4 1.9406900000000002e-14	Pattern Name Homer Significance motif9.motif 3.1472100000000003e-07
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00218962	Pattern Name Homer Significance motif10.motif 0.05677240000000001
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 5.083780000000001e-06 metacluster_1/pattern_12 5.0532e-05	Pattern Name Homer Significance motif3.motif 0.00113343
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.000186519	Pattern Name Homer Significance motif10.motif 0.022038400000000003
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000105105 metacluster_1/pattern_6 0.00560208	Pattern Name Homer Significance motif2.motif 0.000173152 motif10.motif 0.020583599999999997
Cebpg	Pattern Name Modisco Significance metacluster_1/pattern_7 0.007327199999999999	Pattern Name Homer Significance motif5.motif 0.0009311710000000001
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00206537	Pattern Name Homer Significance motif2.motif 0.0065069
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0551822	Pattern Name Homer Significance motif14.motif 0.020632400000000002
Tef	Pattern Name Modisco Significance metacluster_1/pattern_6 0.021059400000000002 metacluster_1/pattern_7 0.0192787	Pattern Name Homer Significance motif5.motif 0.00136578
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0109403 metacluster_1/pattern_7 0.0409806	Pattern Name Homer Significance motif5.motif 0.00448351
Crem	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00274275	Pattern Name Homer Significance motif10.motif 0.0005806359999999999
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00113504	Pattern Name Homer Significance motif3.motif 0.000745397
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 9.044379999999999e-15	Pattern Name Homer Significance motif1.motif 0.0005327719999999999
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_6 1.8692799999999998e-05	Pattern Name Homer Significance motif10.motif 0.0118487
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_4 5.50498e-11	Pattern Name Homer Significance motif9.motif 9.826049999999998e-07
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000138059	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_21 2.02439e-05	Pattern Name Homer Significance motif12.motif 0.00135938
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00206537	Pattern Name Homer Significance motif2.motif 0.011146
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.010173200000000002	Pattern Name Homer Significance motif3.motif 0.00296304
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00302712	Pattern Name Homer Significance motif2.motif 0.00566478
Jun	Pattern Name Modisco Significance metacluster_1/pattern_1 4.02811e-05 metacluster_1/pattern_6 0.0411945	Pattern Name Homer Significance motif2.motif 2.34245e-05 motif5.motif 0.05862769999999999
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0140916	Pattern Name Homer Significance motif3.motif 0.00584325
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00209068	Pattern Name Homer Significance motif2.motif 0.00911012
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_14 0.000993315	Pattern Name Homer Significance motif16.motif 0.00695739
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0230484	Pattern Name Homer Significance motif14.motif 0.019549599999999997
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00169024	Pattern Name Homer Significance motif5.motif 0.00218127
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00593862 metacluster_1/pattern_12 0.00892399	Pattern Name Homer Significance motif3.motif 0.01253
Cebpd	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00228823	Pattern Name Homer Significance motif5.motif 0.00429896

Unique TF-MoDISco TFs: #68

TF Name	Modisco	Homer
Sall4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0449566	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00503428	Absent
Arnt2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0594946	Absent
Maz	Pattern Name Modisco Significance metacluster_1/pattern_12 0.020522400000000003	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.012942799999999999	Absent
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_15 0.000186578	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_17 2.65535e-08	Absent
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00050263	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0009118	Absent
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00579344	Absent
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00498478	Absent
Twist1	Pattern Name Modisco Significance metacluster_1/pattern_9 1.7452300000000002e-23	Absent
Bhlha15	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898	Absent
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_16 7.91091e-09	Absent
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_15 1.2229600000000001e-14	Absent
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00483758	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00124424	Absent
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0177981	Absent
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.018141499999999998	Absent
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0154066	Absent
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_11 0.03967380000000001	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0589148	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0348251 metacluster_1/pattern_12 0.00195036 metacluster_1/pattern_21 0.0415374	Absent
Lmx1b	Pattern Name Modisco Significance metacluster_1/pattern_9 0.05548240000000001	Absent
Ddit3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00721746	Absent
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000158288	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_11 0.019075400000000003	Absent
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00149474	Absent
Tead1	Pattern Name Modisco Significance metacluster_1/pattern_10 0.013194599999999999	Absent
Max	Pattern Name Modisco Significance metacluster_1/pattern_11 0.044927499999999995	Absent
Msc	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898	Absent
Bhlhe22	Pattern Name Modisco Significance metacluster_1/pattern_9 0.05548240000000001	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_3 0.000268785	Absent
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00203461	Absent
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_12 0.012942799999999999	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00209161	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_17 2.73146e-09	Absent
Six1	Pattern Name Modisco Significance metacluster_1/pattern_19 2.12279e-08	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00539874	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00171589	Absent
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0350354	Absent
Six4	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00033983	Absent
Tead4	Pattern Name Modisco Significance metacluster_1/pattern_10 0.04523219999999999	Absent
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0413896	Absent
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_3 6.350409999999999e-06	Absent
Fev	Pattern Name Modisco Significance metacluster_1/pattern_8 0.000623491	Absent
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.042381999999999996	Absent
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_15 5.732090000000001e-10	Absent
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0030294000000000002	Absent
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00203461	Absent
Tcf21	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898	Absent
Tead2	Pattern Name Modisco Significance metacluster_1/pattern_10 0.0313702	Absent
Six2	Pattern Name Modisco Significance metacluster_1/pattern_19 3.3898299999999997e-09	Absent
Lhx5	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898	Absent
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00940006	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000154865	Absent
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_11 0.044927499999999995	Absent
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_16 0.036451599999999994	Absent
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0514217	Absent
Spib	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0551822 metacluster_1/pattern_16 0.00498478	Absent
Lhx1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898	Absent
Neurog1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0401779	Absent
Olig2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0470778	Absent
Lhx3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0332898	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00201018	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_11 0.014529599999999998	Absent
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.029684	Absent
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000700325	Absent

Unique Homer TFs: #8

TF Name	Modisco	Homer
Klf15	Absent	Pattern Name Homer Significance motif3.motif 0.0168827
E2f6	Absent	Pattern Name Homer Significance motif3.motif 0.0237179
Spic	Absent	Pattern Name Homer Significance motif14.motif 0.058806399999999995
E2f7	Absent	Pattern Name Homer Significance motif3.motif 0.00759782
Zbtb1	Absent	Pattern Name Homer Significance motif3.motif 0.00584325
Gmeb2	Absent	Pattern Name Homer Significance motif5.motif 0.0546268
Rxrb	Absent	Pattern Name Homer Significance motif10.motif 0.0298526
Mypop	Absent	Pattern Name Homer Significance motif5.motif 0.043872