In [1]:
# Parameters
data_name = "aB_LPS+IL4_24h;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_88-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_88-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:59:46,561 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeAct B cell 24h
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep11578301245876.9236154544859NANANANANANA
    Modelling Metadata
    MetricValue
    auPRC0.606
    Calibrated Recall at 50% FDR0.215
    Number of Positive Examples in Test Data67883
    Number of Negative Examples in Test Data8002968
    Imbalance Ratio in Test Data0.0084
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #21
Pattern NameTF Name(s)Modisco
metacluster_0/pattern_0 # seqlets: 4182 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp4, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Klf4, Klf8,

Klf1, Egr1, Klf12, Zbtb17, Egr2, E2f1, Klf5, Sp5, Zfp281, Zfx, Zfp740,

Egr3
metacluster_0/pattern_1 # seqlets: 4034 SequenceContrib ScoresHyp_Contrib Scores
Gabpa, Etv6, Ets1, Erg, Fli1, Elk1, Spi1, Etv3, Elk4, Spib,

Elk3, Etv4, XP_911724.4, Etv2, Etv5, Etv1, Spic, Elf4, Irf8, Irf4, Elf1,

Elf2, Ehf, Elf5, Elf3, Fev, Spdef, Irf2, Prdm1, Irf3, Irf1
metacluster_0/pattern_2 # seqlets: 2189 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_0/pattern_3 # seqlets: 1538 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_0/pattern_4 # seqlets: 1366 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Pbx3, Foxi1
metacluster_0/pattern_5 # seqlets: 1007 SequenceContrib ScoresHyp_Contrib Scores
Irf7, Irf9, Stat2, Stat1, Irf5, Irf6
metacluster_0/pattern_6 # seqlets: 1002 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Jdp2, Atf2, Atf7, Creb5, Atf1, Crem, Atf3, Mafb, Jun,

Fosl2, Fosl1, Nfil3, Tef, Rxrb
metacluster_0/pattern_7 # seqlets: 927 SequenceContrib ScoresHyp_Contrib Scores
Wt1, Rfx1, Maz, Klf15
metacluster_0/pattern_8 # seqlets: 842 SequenceContrib ScoresHyp_Contrib Scores
Zscan10
metacluster_0/pattern_9 # seqlets: 693 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42, Usf2, Mxi1
metacluster_0/pattern_10 # seqlets: 647 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfeb, Tfe3, Tfec, Arntl, Mitf, Srebf1, Bhlhe40, Clock, Arnt,

Mlx, Npas2, Srebf2, Creb3l2, Mycn, Tcfl5, Max, Myc, Hlf, Bhlhe41, Dbp,

Xbp1, Mlxip
metacluster_0/pattern_11 # seqlets: 645 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_0/pattern_12 # seqlets: 521 SequenceContrib ScoresHyp_Contrib Scores
Batf, Nfe2, Nfe2l2, Jund, Bach2, Fos, Fosb, Bach1, Junb, Mafk,

Mafa, Mafg, Maff, Maf
metacluster_0/pattern_13 # seqlets: 459 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_0/pattern_14 # seqlets: 364 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2, Pou5f1, Pou2f1, Nanog
metacluster_0/pattern_15 # seqlets: 302 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_0/pattern_16 # seqlets: 287 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_0/pattern_17 # seqlets: 234 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb
metacluster_0/pattern_18 # seqlets: 158 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_19 # seqlets: 87 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2a, Mef2c
metacluster_0/pattern_20 # seqlets: 75 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #154
TF NamePattern(s)
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_02.33918e-06
metacluster_0/pattern_30.047708
metacluster_0/pattern_72.4984699999999998e-05
metacluster_0/pattern_95.917919999999999e-06
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00141811
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_07.59418e-06
metacluster_0/pattern_70.000393952
metacluster_0/pattern_98.79149e-05
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_01.61344e-05
metacluster_0/pattern_70.015499
metacluster_0/pattern_90.0175014
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000432885
metacluster_0/pattern_74.9590600000000006e-05
metacluster_0/pattern_93.61646e-05
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000432885
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00071938
metacluster_0/pattern_70.026848400000000005
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00077981
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.012609299999999999
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00108711
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0467714
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0442566
metacluster_0/pattern_70.026848400000000005
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0171137
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00391853
metacluster_0/pattern_70.00848044
metacluster_0/pattern_90.00754022
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.041511900000000004
metacluster_0/pattern_70.0225899
metacluster_0/pattern_90.0411455
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0103587
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.016900099999999998
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0195822
metacluster_0/pattern_70.0458952
metacluster_0/pattern_90.0441205
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_00.019901
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0230767
metacluster_0/pattern_30.047708
metacluster_0/pattern_70.00114501
metacluster_0/pattern_90.00445796
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0442566
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0467714
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00190498
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00102373
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_14.98633e-05
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_15.07158e-05
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00017790700000000002
metacluster_0/pattern_70.0575229
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000160171
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000378454
metacluster_0/pattern_80.00225679
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_17.21609e-05
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_17.21609e-05
Spib
Pattern NameModiscoSignificance
metacluster_0/pattern_17.21609e-05
metacluster_0/pattern_50.019092599999999998
metacluster_0/pattern_83.87384e-08
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00025849200000000003
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000142286
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_19.10706e-05
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00013995200000000002
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000160171
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000187408
Spic
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00033374800000000003
metacluster_0/pattern_80.0143251
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000285565
Irf8
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000470306
metacluster_0/pattern_50.000215085
metacluster_0/pattern_84.27295e-10
Irf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000470306
metacluster_0/pattern_50.00101973
metacluster_0/pattern_84.494180000000001e-09
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00047960900000000004
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000751722
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00171344
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00226131
metacluster_0/pattern_80.0151821
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00304478
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00176234
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_10.056470299999999994
Irf2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.03546969999999999
metacluster_0/pattern_50.00121065
metacluster_0/pattern_80.00106228
Prdm1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.037631
metacluster_0/pattern_50.000581383
metacluster_0/pattern_80.0180229
Irf3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.056470299999999994
metacluster_0/pattern_50.0370205
metacluster_0/pattern_80.00106228
Irf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.056470299999999994
metacluster_0/pattern_53.47641e-08
metacluster_0/pattern_80.00143452
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_22.94746e-11
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_25.4337e-09
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_36.08274e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_41.2413499999999998e-13
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_42.25736e-10
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_44.51032e-09
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_43.26145e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_46.579349999999999e-06
Irf7
Pattern NameModiscoSignificance
metacluster_0/pattern_57.441669999999999e-06
metacluster_0/pattern_80.010657
Irf9
Pattern NameModiscoSignificance
metacluster_0/pattern_50.000255684
Stat2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.000514189
metacluster_0/pattern_80.034005
Stat1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.00121065
Irf5
Pattern NameModiscoSignificance
metacluster_0/pattern_50.00780578
Irf6
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0396359
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00118801
metacluster_0/pattern_100.0554049
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00118801
metacluster_0/pattern_100.0541187
metacluster_0/pattern_123.27737e-05
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00363363
metacluster_0/pattern_100.0542691
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00139511
metacluster_0/pattern_100.0197546
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00104067
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0111005
metacluster_0/pattern_100.018880200000000003
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_60.012820400000000001
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_60.03558119999999999
metacluster_0/pattern_120.00228995
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_60.011472
metacluster_0/pattern_120.0360266
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_60.058944500000000004
metacluster_0/pattern_120.019272499999999998
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0232021
metacluster_0/pattern_120.004529
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.025069499999999998
metacluster_0/pattern_120.011428
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_60.042075
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0538548
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0538548
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00848044
metacluster_0/pattern_90.0129245
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00848044
metacluster_0/pattern_90.00556396
metacluster_0/pattern_157.76775e-12
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_70.023165099999999997
metacluster_0/pattern_90.0175014
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_70.026848400000000005
Zscan10
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0213992
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_95.07182e-06
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_95.07182e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0102995
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.036459899999999996
metacluster_0/pattern_100.00209615
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0368902
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00414699
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000670311
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00209615
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00193336
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00369649
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0010724999999999999
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0380787
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0118411
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_100.03712530000000001
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0380787
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0118411
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00305049
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00400905
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0190253
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0554049
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0100524
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0541187
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0173672
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0197546
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0203912
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0330519
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0380787
Mlxip
Pattern NameModiscoSignificance
metacluster_0/pattern_100.051255600000000005
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_114.36894e-22
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_113.3068100000000003e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_118.69653e-12
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00219763
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_120.000363847
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00111152
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00219763
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00139447
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00175424
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00190739
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00190739
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_120.023171599999999997
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_120.018264700000000002
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_120.018204599999999998
Mafg
Pattern NameModiscoSignificance
metacluster_0/pattern_120.041411699999999996
Maff
Pattern NameModiscoSignificance
metacluster_0/pattern_120.0432555
Maf
Pattern NameModiscoSignificance
metacluster_0/pattern_120.0432555
Nfkb2
Pattern NameModiscoSignificance
metacluster_0/pattern_133.96681e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_0/pattern_133.96681e-05
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000391954
Relb
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0007710519999999999
Rel
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0170565
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.035832199999999995
Pou5f1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0576222
Pou2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0576222
Nanog
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0576222
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_150.000299138
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0214982
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_152.02819e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_150.000371945
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_150.000673086
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00184542
Runx1
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00232278
Runx2
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00612792
Runx3
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00435057
Cbfb
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00472558
Mef2d
Pattern NameModiscoSignificance
metacluster_0/pattern_198.37235e-08
Mef2a
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000328371
Mef2c
Pattern NameModiscoSignificance
metacluster_0/pattern_192.42707e-06
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #75
TF NameModiscoHomer
Irf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000470306
metacluster_0/pattern_50.00101973
metacluster_0/pattern_84.494180000000001e-09
Pattern NameHomerSignificance
motif1.motif0.0424402
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00108711
Pattern NameHomerSignificance
motif3.motif0.00234399
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0010724999999999999
Pattern NameHomerSignificance
motif5.motif0.04944930000000001
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0442566
metacluster_0/pattern_70.026848400000000005
Pattern NameHomerSignificance
motif3.motif0.0158255
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_14.98633e-05
Pattern NameHomerSignificance
motif1.motif0.00229023
Spic
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00033374800000000003
metacluster_0/pattern_80.0143251
Pattern NameHomerSignificance
motif1.motif0.00767735
Nfkb2
Pattern NameModiscoSignificance
metacluster_0/pattern_133.96681e-05
Pattern NameHomerSignificance
motif21.motif0.011800299999999998
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_07.59418e-06
metacluster_0/pattern_70.000393952
metacluster_0/pattern_98.79149e-05
Pattern NameHomerSignificance
motif3.motif0.00234399
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.016900099999999998
Pattern NameHomerSignificance
motif3.motif0.0299909
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0380787
Pattern NameHomerSignificance
motif5.motif0.051325499999999996
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0118411
Pattern NameHomerSignificance
motif5.motif0.054542499999999994
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00171344
Pattern NameHomerSignificance
motif1.motif0.027799200000000003
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000391954
Pattern NameHomerSignificance
motif21.motif0.026940499999999996
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_46.579349999999999e-06
Pattern NameHomerSignificance
motif6.motif0.00981565
Spib
Pattern NameModiscoSignificance
metacluster_0/pattern_17.21609e-05
metacluster_0/pattern_50.019092599999999998
metacluster_0/pattern_83.87384e-08
Pattern NameHomerSignificance
motif1.motif0.027471100000000002
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000160171
Pattern NameHomerSignificance
motif1.motif0.00011358
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_95.07182e-06
Pattern NameHomerSignificance
motif15.motif0.000298863
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00304478
Pattern NameHomerSignificance
motif1.motif0.00533622
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.012609299999999999
Pattern NameHomerSignificance
motif3.motif0.00135505
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_118.69653e-12
Pattern NameHomerSignificance
motif4.motif2.6096100000000002e-05
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0118411
Pattern NameHomerSignificance
motif5.motif0.050171600000000004
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_43.26145e-06
Pattern NameHomerSignificance
motif6.motif0.00277046
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00190498
Pattern NameHomerSignificance
motif1.motif0.010030200000000001
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00226131
metacluster_0/pattern_80.0151821
Pattern NameHomerSignificance
motif1.motif0.00444107
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0380787
Pattern NameHomerSignificance
motif5.motif0.059249800000000005
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0102995
Pattern NameHomerSignificance
motif15.motif7.48391e-05
Relb
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0007710519999999999
Pattern NameHomerSignificance
motif21.motif0.013338599999999999
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00071938
metacluster_0/pattern_70.026848400000000005
Pattern NameHomerSignificance
motif3.motif0.007224800000000001
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00141811
Pattern NameHomerSignificance
motif3.motif0.000838817
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0203912
Pattern NameHomerSignificance
motif5.motif0.04944930000000001
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_25.4337e-09
Pattern NameHomerSignificance
motif2.motif2.2904e-07
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_01.61344e-05
metacluster_0/pattern_70.015499
metacluster_0/pattern_90.0175014
Pattern NameHomerSignificance
motif3.motif0.000393415
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_02.33918e-06
metacluster_0/pattern_30.047708
metacluster_0/pattern_72.4984699999999998e-05
metacluster_0/pattern_95.917919999999999e-06
Pattern NameHomerSignificance
motif3.motif0.00135505
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_113.3068100000000003e-21
Pattern NameHomerSignificance
motif4.motif1.65007e-08
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00102373
Pattern NameHomerSignificance
motif1.motif0.010030200000000001
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00013995200000000002
Pattern NameHomerSignificance
motif1.motif0.00846711
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_42.25736e-10
Pattern NameHomerSignificance
motif6.motif1.09523e-05
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000187408
Pattern NameHomerSignificance
motif1.motif0.000185907
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00414699
Pattern NameHomerSignificance
motif5.motif0.041320499999999996
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_15.07158e-05
Pattern NameHomerSignificance
motif1.motif0.00143752
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00047960900000000004
Pattern NameHomerSignificance
motif1.motif0.00127643
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_100.03712530000000001
Pattern NameHomerSignificance
motif5.motif0.04944930000000001
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000142286
Pattern NameHomerSignificance
motif1.motif0.00533622
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00017790700000000002
metacluster_0/pattern_70.0575229
Pattern NameHomerSignificance
motif1.motif0.00533622
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00369649
Pattern NameHomerSignificance
motif5.motif0.050171600000000004
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_41.2413499999999998e-13
Pattern NameHomerSignificance
motif6.motif1.07234e-05
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00025849200000000003
Pattern NameHomerSignificance
motif1.motif0.000383229
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_10.056470299999999994
Pattern NameHomerSignificance
motif1.motif0.0234305
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00193336
Pattern NameHomerSignificance
motif5.motif0.050171600000000004
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00305049
Pattern NameHomerSignificance
motif5.motif0.050171600000000004
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0467714
Pattern NameHomerSignificance
motif3.motif0.0299909
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000432885
metacluster_0/pattern_74.9590600000000006e-05
metacluster_0/pattern_93.61646e-05
Pattern NameHomerSignificance
motif3.motif0.012399700000000001
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.036459899999999996
metacluster_0/pattern_100.00209615
Pattern NameHomerSignificance
motif5.motif0.051325499999999996
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_114.36894e-22
Pattern NameHomerSignificance
motif4.motif1.65007e-08
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000432885
Pattern NameHomerSignificance
motif3.motif0.0293467
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00176234
Pattern NameHomerSignificance
motif1.motif0.0380517
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000670311
Pattern NameHomerSignificance
motif5.motif0.041320499999999996
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_22.94746e-11
Pattern NameHomerSignificance
motif2.motif3.97122e-06
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00118801
metacluster_0/pattern_100.0554049
Pattern NameHomerSignificance
motif5.motif0.041320499999999996
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00184542
Pattern NameHomerSignificance
motif11.motif0.000960955
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00209615
Pattern NameHomerSignificance
motif5.motif0.04944930000000001
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_19.10706e-05
Pattern NameHomerSignificance
motif1.motif0.000134068
Irf5
Pattern NameModiscoSignificance
metacluster_0/pattern_50.00780578
Pattern NameHomerSignificance
motif1.motif0.0436905
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00077981
Pattern NameHomerSignificance
motif3.motif0.00234399
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000751722
Pattern NameHomerSignificance
motif1.motif0.039393199999999996
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0171137
Pattern NameHomerSignificance
motif3.motif0.00516431
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_36.08274e-07
Pattern NameHomerSignificance
motif10.motif0.0014662000000000002
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_44.51032e-09
Pattern NameHomerSignificance
motif6.motif1.07234e-05
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000378454
metacluster_0/pattern_80.00225679
Pattern NameHomerSignificance
motif1.motif0.04951219999999999
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_17.21609e-05
Pattern NameHomerSignificance
motif1.motif0.000133385
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000160171
Pattern NameHomerSignificance
motif1.motif0.000682175
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_95.07182e-06
Pattern NameHomerSignificance
motif15.motif0.00320896
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_17.21609e-05
Pattern NameHomerSignificance
motif1.motif0.00127643
Nfkb1
Pattern NameModiscoSignificance
metacluster_0/pattern_133.96681e-05
Pattern NameHomerSignificance
motif21.motif0.011800299999999998
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000285565
Pattern NameHomerSignificance
motif1.motif0.00013345
Unique TF-MoDISco TFs: #79
TF NameModiscoHomer
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00139511
metacluster_0/pattern_100.0197546
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0467714
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00104067
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_70.026848400000000005
Absent
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_120.023171599999999997
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0442566
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.041511900000000004
metacluster_0/pattern_70.0225899
metacluster_0/pattern_90.0411455
Absent
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00219763
Absent
Maf
Pattern NameModiscoSignificance
metacluster_0/pattern_120.0432555
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0100524
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00848044
metacluster_0/pattern_90.00556396
metacluster_0/pattern_157.76775e-12
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0554049
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00111152
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00391853
metacluster_0/pattern_70.00848044
metacluster_0/pattern_90.00754022
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0214982
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_0/pattern_190.000328371
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0197546
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000470306
metacluster_0/pattern_50.000215085
metacluster_0/pattern_84.27295e-10
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_150.000371945
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00400905
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0190253
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.000514189
metacluster_0/pattern_80.034005
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_60.042075
Absent
Maff
Pattern NameModiscoSignificance
metacluster_0/pattern_120.0432555
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_120.018264700000000002
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0538548
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_0/pattern_120.041411699999999996
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00435057
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_60.03558119999999999
metacluster_0/pattern_120.00228995
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.037631
metacluster_0/pattern_50.000581383
metacluster_0/pattern_80.0180229
Absent
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0541187
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_00.019901
Absent
Rel
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0170565
Absent
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_60.058944500000000004
metacluster_0/pattern_120.019272499999999998
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00472558
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0232021
metacluster_0/pattern_120.004529
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_120.018204599999999998
Absent
Nanog
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0576222
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00190739
Absent
Pou5f1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0576222
Absent
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0538548
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_60.011472
metacluster_0/pattern_120.0360266
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0368902
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_0/pattern_57.441669999999999e-06
metacluster_0/pattern_80.010657
Absent
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00175424
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.035832199999999995
Absent
Pou2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0576222
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_150.000673086
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_120.000363847
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00232278
Absent
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_70.023165099999999997
metacluster_0/pattern_90.0175014
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0380787
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.03546969999999999
metacluster_0/pattern_50.00121065
metacluster_0/pattern_80.00106228
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00848044
metacluster_0/pattern_90.0129245
Absent
Irf6
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0396359
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0230767
metacluster_0/pattern_30.047708
metacluster_0/pattern_70.00114501
metacluster_0/pattern_90.00445796
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00190739
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_152.02819e-05
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0195822
metacluster_0/pattern_70.0458952
metacluster_0/pattern_90.0441205
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.025069499999999998
metacluster_0/pattern_120.011428
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00118801
metacluster_0/pattern_100.0541187
metacluster_0/pattern_123.27737e-05
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_0/pattern_100.051255600000000005
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_0/pattern_192.42707e-06
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0330519
Absent
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0173672
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0111005
metacluster_0/pattern_100.018880200000000003
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00139447
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.00121065
Absent
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_120.00219763
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_0/pattern_198.37235e-08
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.00363363
metacluster_0/pattern_100.0542691
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_0/pattern_170.00612792
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_0/pattern_50.000255684
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_150.000299138
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.056470299999999994
metacluster_0/pattern_50.0370205
metacluster_0/pattern_80.00106228
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_0/pattern_80.0213992
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0103587
Absent
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_60.012820400000000001
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.056470299999999994
metacluster_0/pattern_53.47641e-08
metacluster_0/pattern_80.00143452
Absent
Unique Homer TFs: #4
TF NameModiscoHomer
Zic3Absent
Pattern NameHomerSignificance
motif2.motif0.029616800000000002
Hic1Absent
Pattern NameHomerSignificance
motif21.motif0.044312199999999996
Epas1Absent
Pattern NameHomerSignificance
motif5.motif0.059249800000000005
Zic2Absent
Pattern NameHomerSignificance
motif2.motif0.029616800000000002