In [1]:
# Parameters
data_name = "CH12;med14;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_92-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_92-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 19:01:00,233 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typech12 med14 mt
    Cell GroupCancer or Immortalized cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1110526851596.3964195773338NANANANANANA
    Modelling Metadata
    MetricValue
    auPRC0.6213
    Calibrated Recall at 50% FDR0.217
    Number of Positive Examples in Test Data39445
    Number of Negative Examples in Test Data8031406
    Imbalance Ratio in Test Data0.0049
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #18
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5854 SequenceContrib ScoresHyp_Contrib Scores
Spib, Spi1, Irf8, Irf4, Etv6, Ets1, Erg, Gabpa, Spic, Elk1,

Etv2, Ehf, Etv3, Elf4, Elf1, Fli1, Elf3, Elf2, Etv4, XP_911724.4, Elk4,

Elk3, Etv1, Etv5, Prdm1, Irf3, Elf5, Irf2, Irf1, Spdef, Fev
metacluster_1/pattern_1 # seqlets: 3461 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp3, Klf3, Sp1, Sp4, Egr1, Klf4, Zbtb17, Klf5, E2f4,

Sp5, Klf7, Zfp281, Klf6, Klf8, Wt1, Klf12, Maz, Egr2, Klf1, E2f1,

Klf15, Ctcfl, Srebf2, Zfp740
metacluster_1/pattern_2 # seqlets: 2621 SequenceContrib ScoresHyp_Contrib Scores
Ctcf
metacluster_1/pattern_3 # seqlets: 1644 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_4 # seqlets: 1562 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1292 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Rela, Nfkb1, Relb, Rel
metacluster_1/pattern_6 # seqlets: 1099 SequenceContrib ScoresHyp_Contrib Scores
Irf7, Stat2, Stat1, Irf9, Batf3, Irf5
metacluster_1/pattern_7 # seqlets: 982 SequenceContrib ScoresHyp_Contrib Scores
Ebf1, Prdm16
metacluster_1/pattern_8 # seqlets: 958 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfx, Zfp42, Rfx1
metacluster_1/pattern_9 # seqlets: 914 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_10 # seqlets: 772 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf2, Atf7, Usf2, Atf1, Crem, Jdp2, Creb5, Atf3, Fosl2,

Jun, Fosl1, Rxrb, Nfil3, Creb3l2, Tfec
metacluster_1/pattern_11 # seqlets: 684 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_1/pattern_12 # seqlets: 619 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfeb, Arntl, Mitf, Srebf1, Tfe3, Bhlhe40, Clock, Mlx, Arnt,

Npas2, Tcfl5, Bhlhe41, Xbp1, Hlf, Dbp, Hes1
metacluster_1/pattern_13 # seqlets: 520 SequenceContrib ScoresHyp_Contrib Scores
E2f7, Bcl6, Sall4
metacluster_1/pattern_14 # seqlets: 437 SequenceContrib ScoresHyp_Contrib Scores
Batf, Fosb, Jund, Junb, Fos, Bach2, Nfe2, Nfe2l2, Bach1, Mafk,

Mafb, Mafa, Mafg, Maff, Maf
metacluster_1/pattern_15 # seqlets: 363 SequenceContrib ScoresHyp_Contrib Scores
Mef2a, Mef2d, Mef2c
metacluster_1/pattern_16 # seqlets: 291 SequenceContrib ScoresHyp_Contrib Scores
Rfx2, Rfx3, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_17 # seqlets: 242 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
Click here for Motifs by TF-MoDISco: #145
TF NamePattern(s)
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_01.4985499999999998e-06
metacluster_1/pattern_67.47772e-05
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00028184
metacluster_1/pattern_60.0335766
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_03.35677e-05
metacluster_1/pattern_61.73275e-07
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_03.92321e-05
metacluster_1/pattern_60.00280829
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00208283
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00029281099999999997
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000385311
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00379386
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00028184
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00034481199999999995
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00029281099999999997
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00208283
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00034481199999999995
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00034481199999999995
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00036162
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00244253
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00458455
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726463
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00138253
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000448308
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00124349
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00109085
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00145227
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00124349
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00140989
metacluster_1/pattern_60.00341795
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00145418
metacluster_1/pattern_60.024406900000000002
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00742475
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00234303
metacluster_1/pattern_60.00373727
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00371213
metacluster_1/pattern_61.73275e-07
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0108871
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0127447
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_15.623200000000001e-10
metacluster_1/pattern_85.76845e-05
metacluster_1/pattern_138.19429e-06
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_16.47795e-09
metacluster_1/pattern_80.000239061
metacluster_1/pattern_133.932380000000001e-06
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_19.41831e-08
metacluster_1/pattern_80.0265361
metacluster_1/pattern_130.000395091
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000302787
metacluster_1/pattern_87.01542e-05
metacluster_1/pattern_130.022856900000000003
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00126197
metacluster_1/pattern_130.0423524
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0249565
metacluster_1/pattern_130.00107983
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000848547
metacluster_1/pattern_130.00212346
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000204677
metacluster_1/pattern_80.00934548
metacluster_1/pattern_131.19875e-08
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000302787
metacluster_1/pattern_130.00166615
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00038088699999999995
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000531396
metacluster_1/pattern_134.08027e-05
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000634531
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00156682
metacluster_1/pattern_130.0041741999999999994
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00097015
metacluster_1/pattern_130.0041741999999999994
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00106011
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00106011
metacluster_1/pattern_80.0265361
metacluster_1/pattern_134.08027e-05
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00118458
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00424401
metacluster_1/pattern_80.0265361
metacluster_1/pattern_131.20553e-06
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00444277
metacluster_1/pattern_80.0467184
metacluster_1/pattern_130.0083182
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021090900000000003
metacluster_1/pattern_130.0165505
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021090900000000003
metacluster_1/pattern_130.027978899999999998
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021090900000000003
metacluster_1/pattern_131.3319e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0316603
metacluster_1/pattern_22.77872e-08
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.047717
metacluster_1/pattern_120.0041278999999999995
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0571711
metacluster_1/pattern_130.0148643
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_23.48984e-11
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.64221e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_46.66253e-12
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_43.80609e-11
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_45.45035e-11
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_46.48484e-07
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_43.66486e-06
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_55.670940000000001e-10
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00014414200000000002
metacluster_1/pattern_130.0009903730000000001
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.9686000000000003e-06
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_53.31886e-06
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0221775
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.000863635
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00170804
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00231603
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00280829
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00899793
Irf5
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0159832
Ebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000232146
Prdm16
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00638628
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_84.070159999999999e-06
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_85.816180000000001e-06
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0023710999999999997
metacluster_1/pattern_100.0345825
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_80.010779500000000001
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0265361
metacluster_1/pattern_161.37582e-10
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_92.8601999999999994e-23
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_96.69944e-23
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_97.31107e-13
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00290802
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000974535
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000406855
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000154001
metacluster_1/pattern_120.00304618
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0217115
metacluster_1/pattern_120.0138435
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0151733
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000753187
metacluster_1/pattern_141.1256500000000001e-05
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000974535
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00499469
metacluster_1/pattern_140.000539446
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.016981200000000002
metacluster_1/pattern_140.00123035
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0345825
metacluster_1/pattern_140.0253057
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.035245099999999994
metacluster_1/pattern_140.037288199999999994
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.038458400000000004
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0547845
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0547845
metacluster_1/pattern_120.0509119
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_100.056323000000000005
metacluster_1/pattern_120.00244741
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00729603
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00344463
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00116314
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00496533
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00146836
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00304618
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00263423
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00998351
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.024339
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0236083
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0399651
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00177726
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00571925
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0160093
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0399651
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.05158719999999999
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0557159
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0570861
E2f7
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0320335
Bcl6
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0320335
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0560816
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00386062
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00037167099999999996
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00306481
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0130168
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000771658
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00412634
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00561876
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00746671
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00724497
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_140.019876400000000002
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0318571
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0256219
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_140.037025999999999996
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_140.047649199999999996
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0575552
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_150.000118275
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_157.254069999999999e-10
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_157.381770000000001e-09
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_167.00563e-09
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00160181
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_167.75422e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00067774
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00160348
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_172.13096e-05
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #81
TF NameModiscoHomer
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.9686000000000003e-06
Pattern NameHomerSignificance
motif10.motif0.00234323
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00034481199999999995
Pattern NameHomerSignificance
motif1.motif0.000672095
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00496533
Pattern NameHomerSignificance
motif5.motif0.0341287
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_80.010779500000000001
Pattern NameHomerSignificance
motif11.motif0.00858732
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00014414200000000002
metacluster_1/pattern_130.0009903730000000001
Pattern NameHomerSignificance
motif10.motif0.00567904
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0316603
metacluster_1/pattern_22.77872e-08
Pattern NameHomerSignificance
motif8.motif0.000615096
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00028184
Pattern NameHomerSignificance
motif1.motif0.00565604
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00116314
Pattern NameHomerSignificance
motif5.motif0.0111797
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00029281099999999997
Pattern NameHomerSignificance
motif1.motif0.00106914
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00742475
Pattern NameHomerSignificance
motif1.motif0.00119089
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00097015
metacluster_1/pattern_130.0041741999999999994
Pattern NameHomerSignificance
motif2.motif0.00234315
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0221775
Pattern NameHomerSignificance
motif10.motif0.013957299999999997
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.024339
Pattern NameHomerSignificance
motif5.motif0.0182055
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000634531
Pattern NameHomerSignificance
motif2.motif0.000696145
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_97.31107e-13
Pattern NameHomerSignificance
motif4.motif4.78052e-06
Irf5
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0159832
Pattern NameHomerSignificance
motif1.motif0.0464997
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_19.41831e-08
metacluster_1/pattern_80.0265361
metacluster_1/pattern_130.000395091
Pattern NameHomerSignificance
motif2.motif0.000696145
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00036162
Pattern NameHomerSignificance
motif1.motif0.00038041
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00208283
Pattern NameHomerSignificance
motif1.motif0.0116241
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_46.48484e-07
Pattern NameHomerSignificance
motif3.motif1.22075e-05
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0399651
Pattern NameHomerSignificance
motif5.motif0.0207828
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000154001
metacluster_1/pattern_120.00304618
Pattern NameHomerSignificance
motif5.motif0.0182055
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_43.80609e-11
Pattern NameHomerSignificance
motif3.motif7.403069999999999e-07
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0127447
Pattern NameHomerSignificance
motif1.motif0.0100941
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00028184
metacluster_1/pattern_60.0335766
Pattern NameHomerSignificance
motif1.motif0.027923000000000003
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0249565
metacluster_1/pattern_130.00107983
Pattern NameHomerSignificance
motif2.motif0.028457099999999996
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_43.66486e-06
Pattern NameHomerSignificance
motif3.motif4.20679e-05
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00146836
Pattern NameHomerSignificance
motif5.motif0.050264300000000005
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00499469
metacluster_1/pattern_140.000539446
Pattern NameHomerSignificance
motif5.motif0.0481261
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_23.48984e-11
Pattern NameHomerSignificance
motif8.motif0.00039568800000000005
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00344463
Pattern NameHomerSignificance
motif5.motif0.0111797
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00106011
Pattern NameHomerSignificance
motif2.motif0.0011252
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00263423
Pattern NameHomerSignificance
motif5.motif0.0182055
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00177726
Pattern NameHomerSignificance
motif5.motif0.0182055
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000848547
metacluster_1/pattern_130.00212346
Pattern NameHomerSignificance
motif2.motif0.000696145
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00126197
metacluster_1/pattern_130.0423524
Pattern NameHomerSignificance
motif2.motif0.028457099999999996
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000302787
metacluster_1/pattern_87.01542e-05
metacluster_1/pattern_130.022856900000000003
Pattern NameHomerSignificance
motif2.motif0.0073593
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00998351
Pattern NameHomerSignificance
motif5.motif0.0195262
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00208283
Pattern NameHomerSignificance
motif1.motif0.0177755
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_53.31886e-06
Pattern NameHomerSignificance
motif10.motif0.00328182
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_96.69944e-23
Pattern NameHomerSignificance
motif4.motif6.17151e-08
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0160093
Pattern NameHomerSignificance
motif5.motif0.0182055
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_84.070159999999999e-06
Pattern NameHomerSignificance
motif11.motif0.000261186
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00458455
Pattern NameHomerSignificance
motif1.motif0.029227
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_01.4985499999999998e-06
metacluster_1/pattern_67.47772e-05
Pattern NameHomerSignificance
motif1.motif0.029996699999999998
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000448308
Pattern NameHomerSignificance
motif1.motif7.52237e-05
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00034481199999999995
Pattern NameHomerSignificance
motif1.motif5.43317e-05
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0236083
Pattern NameHomerSignificance
motif5.motif0.0341287
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00290802
Pattern NameHomerSignificance
motif5.motif0.0402636
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_172.13096e-05
Pattern NameHomerSignificance
motif15.motif3.01449e-07
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00379386
Pattern NameHomerSignificance
motif1.motif0.00565604
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_45.45035e-11
Pattern NameHomerSignificance
motif3.motif4.0683700000000003e-07
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0399651
Pattern NameHomerSignificance
motif5.motif0.0398769
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000302787
metacluster_1/pattern_130.00166615
Pattern NameHomerSignificance
motif2.motif0.028457099999999996
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0217115
metacluster_1/pattern_120.0138435
Pattern NameHomerSignificance
motif5.motif0.037829
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726463
Pattern NameHomerSignificance
motif1.motif0.0117146
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00145227
Pattern NameHomerSignificance
motif1.motif0.000143625
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00118458
Pattern NameHomerSignificance
motif2.motif0.021580000000000002
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0023710999999999997
metacluster_1/pattern_100.0345825
Pattern NameHomerSignificance
motif2.motif0.028457099999999996
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000753187
metacluster_1/pattern_141.1256500000000001e-05
Pattern NameHomerSignificance
motif5.motif0.043881800000000006
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00138253
Pattern NameHomerSignificance
motif1.motif0.0040088
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000385311
Pattern NameHomerSignificance
motif1.motif0.00106914
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00729603
Pattern NameHomerSignificance
motif6.motif0.00483249
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00304618
Pattern NameHomerSignificance
motif5.motif0.058812699999999996
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_85.816180000000001e-06
Pattern NameHomerSignificance
motif11.motif6.2863e-06
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00244253
Pattern NameHomerSignificance
motif1.motif0.00150245
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00029281099999999997
Pattern NameHomerSignificance
motif1.motif0.0040088
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_92.8601999999999994e-23
Pattern NameHomerSignificance
motif4.motif8.694150000000001e-08
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0108871
Pattern NameHomerSignificance
motif1.motif0.00675202
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00034481199999999995
Pattern NameHomerSignificance
motif1.motif0.000139484
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_15.623200000000001e-10
metacluster_1/pattern_85.76845e-05
metacluster_1/pattern_138.19429e-06
Pattern NameHomerSignificance
motif2.motif0.000696145
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.64221e-07
Pattern NameHomerSignificance
motif7.motif1.24108e-06
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00124349
Pattern NameHomerSignificance
motif1.motif0.00038041
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00038088699999999995
Pattern NameHomerSignificance
motif2.motif0.000696145
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_100.056323000000000005
metacluster_1/pattern_120.00244741
Pattern NameHomerSignificance
motif5.motif0.0182055
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_55.670940000000001e-10
Pattern NameHomerSignificance
motif10.motif0.00575366
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00109085
Pattern NameHomerSignificance
motif1.motif0.000602849
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_16.47795e-09
metacluster_1/pattern_80.000239061
metacluster_1/pattern_133.932380000000001e-06
Pattern NameHomerSignificance
motif2.motif0.000971202
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00124349
Pattern NameHomerSignificance
motif1.motif5.92184e-05
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_46.66253e-12
Pattern NameHomerSignificance
motif3.motif1.64372e-09
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021090900000000003
metacluster_1/pattern_130.0165505
Pattern NameHomerSignificance
motif2.motif0.0505056
Unique TF-MoDISco TFs: #64
TF NameModiscoHomer
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00037167099999999996
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00234303
metacluster_1/pattern_60.00373727
Absent
Ebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000232146
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00170804
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00561876
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_140.019876400000000002
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0560816
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00160181
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0151733
Absent
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0570861
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00280829
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000531396
metacluster_1/pattern_134.08027e-05
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000974535
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00899793
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00724497
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0265361
metacluster_1/pattern_161.37582e-10
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0571711
metacluster_1/pattern_130.0148643
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0345825
metacluster_1/pattern_140.0253057
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000974535
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0557159
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_03.35677e-05
metacluster_1/pattern_61.73275e-07
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_157.381770000000001e-09
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00386062
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021090900000000003
metacluster_1/pattern_130.027978899999999998
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.047717
metacluster_1/pattern_120.0041278999999999995
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00231603
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0575552
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00145418
metacluster_1/pattern_60.024406900000000002
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.035245099999999994
metacluster_1/pattern_140.037288199999999994
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000204677
metacluster_1/pattern_80.00934548
metacluster_1/pattern_131.19875e-08
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0318571
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00306481
Absent
E2f7
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0320335
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00571925
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_140.047649199999999996
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00067774
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0130168
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000406855
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00160348
Absent
Bcl6
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0320335
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.038458400000000004
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_157.254069999999999e-10
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000771658
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00140989
metacluster_1/pattern_60.00341795
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0547845
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0547845
metacluster_1/pattern_120.0509119
Absent
Prdm16
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00638628
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_03.92321e-05
metacluster_1/pattern_60.00280829
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00156682
metacluster_1/pattern_130.0041741999999999994
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.016981200000000002
metacluster_1/pattern_140.00123035
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_167.75422e-05
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00746671
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021090900000000003
metacluster_1/pattern_131.3319e-05
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.000863635
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00106011
metacluster_1/pattern_80.0265361
metacluster_1/pattern_134.08027e-05
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00444277
metacluster_1/pattern_80.0467184
metacluster_1/pattern_130.0083182
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.05158719999999999
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00412634
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_167.00563e-09
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00424401
metacluster_1/pattern_80.0265361
metacluster_1/pattern_131.20553e-06
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0256219
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_140.037025999999999996
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00371213
metacluster_1/pattern_61.73275e-07
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_150.000118275
Absent
Unique Homer TFs: #4
TF NameModiscoHomer
Pou5f1Absent
Pattern NameHomerSignificance
motif6.motif0.015379599999999998
NanogAbsent
Pattern NameHomerSignificance
motif6.motif0.015379599999999998
Epas1Absent
Pattern NameHomerSignificance
motif5.motif0.0245439
Zbtb1Absent
Pattern NameHomerSignificance
motif2.motif0.0505056