In [1]:
# Parameters
data_name = "testis;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_60-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_60-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:53:24,268 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typetestis
    Cell GroupOther Tissues
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep148630305676.21865448727427512810.050540374740.0741182076070.3343
    Modelling Metadata
    MetricValue
    auPRC0.7878
    Calibrated Recall at 50% FDR0.126
    Number of Positive Examples in Test Data36968
    Number of Negative Examples in Test Data8033883
    Imbalance Ratio in Test Data0.0046
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #21
Pattern NameTF Name(s)Modisco
metacluster_0/pattern_0 # seqlets: 1761 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf6, Klf4, Klf7, Egr1,

Klf1, Klf8, Klf12, Zbtb17, E2f1, Egr2, Zfx, Zfp281, Sp5, Klf5, Zfp740
metacluster_0/pattern_1 # seqlets: 1718 SequenceContrib ScoresHyp_Contrib Scores
Fli1, Gabpa, Elk4, Elk1, Ets1, Erg, Elf1, Fev, Etv5, Elk3,

Etv2, Etv4, Etv1, Etv6, Ehf, Elf2, Etv3, XP_911724.4, Elf5, Elf4, Elf3,

Spi1, Spdef
metacluster_0/pattern_2 # seqlets: 1403 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_0/pattern_3 # seqlets: 1358 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Jdp2, Creb5, Atf1, Atf7, Atf2, Crem, Jun, Atf3, Xbp1,

Fosl1, Mafb, Nfil3, Gmeb2, Fosl2, Jund, Tef, Gmeb1
metacluster_0/pattern_4 # seqlets: 1343 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_0/pattern_5 # seqlets: 1155 SequenceContrib ScoresHyp_Contrib Scores
Rfx1, Usf2, Mxi1, Ctcfl, Ctcf, Klf15, Wt1
metacluster_0/pattern_6 # seqlets: 820 SequenceContrib ScoresHyp_Contrib Scores
Zbtb14, Tfap2b
metacluster_0/pattern_7 # seqlets: 817 SequenceContrib ScoresHyp_Contrib Scores
Maz, Egr3, Nr1h4
metacluster_0/pattern_8 # seqlets: 803 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42
metacluster_0/pattern_9 # seqlets: 571 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_0/pattern_10 # seqlets: 540 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_11 # seqlets: 484 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_0/pattern_12 # seqlets: 440 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_0/pattern_13 # seqlets: 409 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_14 # seqlets: 287 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfeb, Tfe3, Arntl, Tfec, Mitf, Bhlhe40, Clock, Srebf1, Arnt,

Mlx, Npas2, Srebf2, Tcfl5, Mycn, Creb3l2, Max, Myc, Bhlhe41, Hlf, Rxrg
metacluster_0/pattern_15 # seqlets: 290 SequenceContrib ScoresHyp_Contrib Scores
Dbp, Rxrb
metacluster_0/pattern_16 # seqlets: 197 SequenceContrib ScoresHyp_Contrib Scores
Mybl2, Mybl1, Klf9, Irf6, E2f3, E2f6
metacluster_0/pattern_17 # seqlets: 174 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_18 # seqlets: 86 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_19 # seqlets: 43 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_20 # seqlets: 36 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #121
TF NamePattern(s)
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00242041
metacluster_0/pattern_70.00922237
metacluster_0/pattern_140.053264599999999995
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_02.19798e-06
metacluster_0/pattern_54.5904e-06
metacluster_0/pattern_67.95086e-05
metacluster_0/pattern_73.80524e-11
metacluster_0/pattern_80.0310108
metacluster_0/pattern_110.00557598
metacluster_0/pattern_144.4578e-05
metacluster_0/pattern_161.24768e-05
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_01.0341600000000001e-05
metacluster_0/pattern_54.5405e-05
metacluster_0/pattern_60.00042464900000000003
metacluster_0/pattern_76.7694e-10
metacluster_0/pattern_80.022816299999999998
metacluster_0/pattern_110.00557598
metacluster_0/pattern_140.00041059
metacluster_0/pattern_169.85125e-05
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_02.9825799999999998e-05
metacluster_0/pattern_50.0008585060000000001
metacluster_0/pattern_60.0116458
metacluster_0/pattern_79.37892e-09
metacluster_0/pattern_140.00531886
metacluster_0/pattern_160.013706999999999999
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0008380169999999999
metacluster_0/pattern_52.1735199999999998e-05
metacluster_0/pattern_60.00042464900000000003
metacluster_0/pattern_70.000731289
metacluster_0/pattern_110.0247607
metacluster_0/pattern_140.000300893
metacluster_0/pattern_162.095e-05
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000423285
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0008428410000000001
metacluster_0/pattern_50.014026400000000001
metacluster_0/pattern_74.47115e-06
metacluster_0/pattern_160.0437486
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0200768
metacluster_0/pattern_70.00091201
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00117489
metacluster_0/pattern_70.000268464
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00278035
metacluster_0/pattern_50.0342205
metacluster_0/pattern_70.00356753
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_50.033891199999999996
metacluster_0/pattern_70.0191726
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00172139
metacluster_0/pattern_70.00057782
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0200768
metacluster_0/pattern_70.000523494
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00386044
metacluster_0/pattern_50.00339711
metacluster_0/pattern_60.029433099999999997
metacluster_0/pattern_70.000268464
metacluster_0/pattern_140.0382013
metacluster_0/pattern_160.00223051
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00805408
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.046299900000000005
metacluster_0/pattern_70.0119973
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_50.00344136
metacluster_0/pattern_60.00218333
metacluster_0/pattern_70.000731289
metacluster_0/pattern_110.00474658
metacluster_0/pattern_140.026680400000000003
metacluster_0/pattern_160.000904643
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_70.05466569999999999
metacluster_0/pattern_160.0564073
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_71.69189e-05
metacluster_0/pattern_160.00751272
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_70.000268464
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_00.041231800000000006
metacluster_0/pattern_130.019630599999999998
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00461996
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00277298
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00277298
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00236129
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00435886
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00461996
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000100735
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00039246800000000004
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00102271
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00183162
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00236129
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00785202
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00356799
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.038316300000000005
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0076932
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.030483499999999997
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00580859
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00618909
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0482124
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0234271
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.028663799999999996
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0483836
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_10.030483499999999997
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_25.75802e-15
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_28.91871e-12
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_28.91871e-12
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_23.82391e-07
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_24.686309999999999e-06
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000813455
metacluster_0/pattern_140.0382013
metacluster_0/pattern_150.05842869999999999
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00651026
metacluster_0/pattern_140.04231819999999999
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000923905
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00360924
metacluster_0/pattern_140.053951599999999995
metacluster_0/pattern_150.0232129
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00301037
metacluster_0/pattern_140.021502700000000003
metacluster_0/pattern_150.031749599999999996
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00998638
metacluster_0/pattern_140.0342869
metacluster_0/pattern_150.049726
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_30.015377100000000001
metacluster_0/pattern_150.0510491
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0488065
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0325144
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0325144
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.033948400000000004
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Gmeb2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0456075
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0488065
Gmeb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.056139499999999995
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_46.039009999999999e-06
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.00468754
metacluster_0/pattern_60.0354883
metacluster_0/pattern_70.03468
metacluster_0/pattern_80.0547828
metacluster_0/pattern_92.5254699999999997e-08
metacluster_0/pattern_140.010878200000000001
metacluster_0/pattern_160.027570599999999997
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.012318
metacluster_0/pattern_60.00218333
metacluster_0/pattern_70.0005354719999999999
metacluster_0/pattern_110.00557598
metacluster_0/pattern_140.0121125
metacluster_0/pattern_160.0191604
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.014026400000000001
metacluster_0/pattern_60.016277899999999998
metacluster_0/pattern_70.0053488
metacluster_0/pattern_80.0498281
metacluster_0/pattern_140.0047717
metacluster_0/pattern_160.0334594
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_50.014026400000000001
metacluster_0/pattern_60.014566399999999998
metacluster_0/pattern_70.0191726
metacluster_0/pattern_106.16616e-12
metacluster_0/pattern_140.04231819999999999
metacluster_0/pattern_160.0498788
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_50.033891199999999996
metacluster_0/pattern_60.030380900000000002
metacluster_0/pattern_70.0216229
metacluster_0/pattern_101.4921799999999998e-07
metacluster_0/pattern_160.0564073
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0427255
metacluster_0/pattern_70.000268464
metacluster_0/pattern_160.00239282
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0460777
metacluster_0/pattern_76.511140000000001e-05
metacluster_0/pattern_140.0382013
metacluster_0/pattern_160.00022232
Zbtb14
Pattern NameModiscoSignificance
metacluster_0/pattern_60.030380900000000002
Tfap2b
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0490168
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000268464
metacluster_0/pattern_140.053951599999999995
metacluster_0/pattern_160.000742798
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.011826799999999998
Nr1h4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0119973
metacluster_0/pattern_140.024172700000000002
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_82.39041e-06
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_87.96087e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_80.022816299999999998
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00304375
metacluster_0/pattern_130.019630599999999998
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_97.470210000000001e-08
metacluster_0/pattern_130.0400804
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_90.000282188
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00232166
metacluster_0/pattern_130.019630599999999998
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00156261
metacluster_0/pattern_130.000577106
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000843899
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_121.51138e-22
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_128.468599999999999e-20
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_121.02297e-12
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.037256300000000006
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0007156269999999999
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00200581
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_140.008718700000000001
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00211126
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00106014
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0180534
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0255891
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.010878200000000001
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_140.041755099999999996
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0121125
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00347749
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00748804
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00961078
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0178365
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0382013
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0270385
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0382013
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0385144
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0392671
Rxrg
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0538275
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0574869
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0574869
Mybl2
Pattern NameModiscoSignificance
metacluster_0/pattern_160.000742798
Mybl1
Pattern NameModiscoSignificance
metacluster_0/pattern_160.0109554
Klf9
Pattern NameModiscoSignificance
metacluster_0/pattern_160.013706999999999999
Irf6
Pattern NameModiscoSignificance
metacluster_0/pattern_160.0334594
E2f3
Pattern NameModiscoSignificance
metacluster_0/pattern_160.0444462
E2f6
Pattern NameModiscoSignificance
metacluster_0/pattern_160.047057
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #71
TF NameModiscoHomer
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_02.9825799999999998e-05
metacluster_0/pattern_50.0008585060000000001
metacluster_0/pattern_60.0116458
metacluster_0/pattern_79.37892e-09
metacluster_0/pattern_140.00531886
metacluster_0/pattern_160.013706999999999999
Pattern NameHomerSignificance
motif1.motif0.00015296
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_01.0341600000000001e-05
metacluster_0/pattern_54.5405e-05
metacluster_0/pattern_60.00042464900000000003
metacluster_0/pattern_76.7694e-10
metacluster_0/pattern_80.022816299999999998
metacluster_0/pattern_110.00557598
metacluster_0/pattern_140.00041059
metacluster_0/pattern_169.85125e-05
Pattern NameHomerSignificance
motif1.motif0.000155095
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00277298
Pattern NameHomerSignificance
motif3.motif0.000992822
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00435886
Pattern NameHomerSignificance
motif3.motif0.00225873
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.046299900000000005
metacluster_0/pattern_70.0119973
Pattern NameHomerSignificance
motif1.motif0.0308367
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0200768
metacluster_0/pattern_70.00091201
Pattern NameHomerSignificance
motif1.motif0.0228017
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00278035
metacluster_0/pattern_50.0342205
metacluster_0/pattern_70.00356753
Pattern NameHomerSignificance
motif1.motif0.0118484
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000100735
Pattern NameHomerSignificance
motif3.motif0.00106079
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00102271
Pattern NameHomerSignificance
motif3.motif0.000487586
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00172139
metacluster_0/pattern_70.00057782
Pattern NameHomerSignificance
motif1.motif0.000303205
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00651026
metacluster_0/pattern_140.04231819999999999
Pattern NameHomerSignificance
motif5.motif0.036303800000000004
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0008428410000000001
metacluster_0/pattern_50.014026400000000001
metacluster_0/pattern_74.47115e-06
metacluster_0/pattern_160.0437486
Pattern NameHomerSignificance
motif1.motif0.0008697889999999999
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_50.033891199999999996
metacluster_0/pattern_70.0191726
Pattern NameHomerSignificance
motif1.motif0.015149600000000001
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00461996
Pattern NameHomerSignificance
motif3.motif0.00185978
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0076932
Pattern NameHomerSignificance
motif3.motif0.0462152
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_30.015377100000000001
metacluster_0/pattern_150.0510491
Pattern NameHomerSignificance
motif5.motif0.021784599999999998
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_140.008718700000000001
Pattern NameHomerSignificance
motif5.motif0.0449509
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000923905
Pattern NameHomerSignificance
motif5.motif0.017525299999999997
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00998638
metacluster_0/pattern_140.0342869
metacluster_0/pattern_150.049726
Pattern NameHomerSignificance
motif5.motif0.036303800000000004
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000813455
metacluster_0/pattern_140.0382013
metacluster_0/pattern_150.05842869999999999
Pattern NameHomerSignificance
motif5.motif0.021784599999999998
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00117489
metacluster_0/pattern_70.000268464
Pattern NameHomerSignificance
motif1.motif0.000155095
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.030483499999999997
Pattern NameHomerSignificance
motif3.motif0.0449963
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_121.02297e-12
Pattern NameHomerSignificance
motif4.motif3.41954e-05
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00961078
Pattern NameHomerSignificance
motif8.motif0.0252135
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00461996
Pattern NameHomerSignificance
motif3.motif0.0019099
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_28.91871e-12
Pattern NameHomerSignificance
motif2.motif4.5757099999999996e-08
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00039246800000000004
Pattern NameHomerSignificance
motif3.motif0.00254355
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0482124
Pattern NameHomerSignificance
motif3.motif0.053600199999999994
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_23.82391e-07
Pattern NameHomerSignificance
motif2.motif5.68523e-05
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00301037
metacluster_0/pattern_140.021502700000000003
metacluster_0/pattern_150.031749599999999996
Pattern NameHomerSignificance
motif5.motif0.036303800000000004
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00200581
Pattern NameHomerSignificance
motif5.motif0.0447578
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_24.686309999999999e-06
Pattern NameHomerSignificance
motif2.motif0.00023648400000000002
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00785202
Pattern NameHomerSignificance
motif3.motif0.0111279
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00618909
Pattern NameHomerSignificance
motif3.motif0.00254355
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.028663799999999996
Pattern NameHomerSignificance
motif3.motif0.05492090000000001
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00242041
metacluster_0/pattern_70.00922237
metacluster_0/pattern_140.053264599999999995
Pattern NameHomerSignificance
motif1.motif0.0162483
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00304375
metacluster_0/pattern_130.019630599999999998
Pattern NameHomerSignificance
motif9.motif0.0249243
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000423285
Pattern NameHomerSignificance
motif1.motif0.000303205
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00580859
Pattern NameHomerSignificance
motif3.motif0.00261074
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_87.96087e-06
Pattern NameHomerSignificance
motif15.motif0.016778599999999998
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_128.468599999999999e-20
Pattern NameHomerSignificance
motif4.motif9.19496e-07
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_97.470210000000001e-08
metacluster_0/pattern_130.0400804
Pattern NameHomerSignificance
motif9.motif0.0584289
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0008380169999999999
metacluster_0/pattern_52.1735199999999998e-05
metacluster_0/pattern_60.00042464900000000003
metacluster_0/pattern_70.000731289
metacluster_0/pattern_110.0247607
metacluster_0/pattern_140.000300893
metacluster_0/pattern_162.095e-05
Pattern NameHomerSignificance
motif1.motif0.0056093
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00277298
Pattern NameHomerSignificance
motif3.motif0.0015566
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0180534
Pattern NameHomerSignificance
motif5.motif0.0519111
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.038316300000000005
Pattern NameHomerSignificance
motif3.motif0.025970299999999998
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0325144
Pattern NameHomerSignificance
motif5.motif0.033003199999999996
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00360924
metacluster_0/pattern_140.053951599999999995
metacluster_0/pattern_150.0232129
Pattern NameHomerSignificance
motif5.motif0.036303800000000004
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_70.000268464
Pattern NameHomerSignificance
motif1.motif0.00906286
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_02.19798e-06
metacluster_0/pattern_54.5904e-06
metacluster_0/pattern_67.95086e-05
metacluster_0/pattern_73.80524e-11
metacluster_0/pattern_80.0310108
metacluster_0/pattern_110.00557598
metacluster_0/pattern_144.4578e-05
metacluster_0/pattern_161.24768e-05
Pattern NameHomerSignificance
motif1.motif0.00015296
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00805408
Pattern NameHomerSignificance
motif1.motif0.0438529
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0483836
Pattern NameHomerSignificance
motif3.motif0.0111279
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000843899
Pattern NameHomerSignificance
motif10.motif0.000284423
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_10.030483499999999997
Pattern NameHomerSignificance
motif3.motif0.016884
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0255891
Pattern NameHomerSignificance
motif5.motif0.0428099
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00156261
metacluster_0/pattern_130.000577106
Pattern NameHomerSignificance
motif9.motif0.0110671
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_28.91871e-12
Pattern NameHomerSignificance
motif2.motif3.23852e-07
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00236129
Pattern NameHomerSignificance
motif3.motif0.00086262
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0234271
Pattern NameHomerSignificance
motif3.motif0.0028565
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0007156269999999999
Pattern NameHomerSignificance
motif5.motif0.036303800000000004
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_46.039009999999999e-06
Pattern NameHomerSignificance
motif6.motif7.314400000000001e-06
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_90.000282188
Pattern NameHomerSignificance
motif9.motif0.00011564299999999999
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_121.51138e-22
Pattern NameHomerSignificance
motif4.motif9.19496e-07
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.00468754
metacluster_0/pattern_60.0354883
metacluster_0/pattern_70.03468
metacluster_0/pattern_80.0547828
metacluster_0/pattern_92.5254699999999997e-08
metacluster_0/pattern_140.010878200000000001
metacluster_0/pattern_160.027570599999999997
Pattern NameHomerSignificance
motif9.motif1.0791600000000001e-07
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00183162
Pattern NameHomerSignificance
motif3.motif0.000992822
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00356799
Pattern NameHomerSignificance
motif3.motif0.00115739
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_25.75802e-15
Pattern NameHomerSignificance
motif2.motif8.48518e-09
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0200768
metacluster_0/pattern_70.000523494
Pattern NameHomerSignificance
motif1.motif0.00601437
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00232166
metacluster_0/pattern_130.019630599999999998
Pattern NameHomerSignificance
motif9.motif0.00939154
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00236129
Pattern NameHomerSignificance
motif3.motif0.013025700000000001
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0574869
Pattern NameHomerSignificance
motif5.motif0.0449509
Unique TF-MoDISco TFs: #50
TF NameModiscoHomer
Gmeb2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0382013
Absent
Mybl2
Pattern NameModiscoSignificance
metacluster_0/pattern_160.000742798
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0460777
metacluster_0/pattern_76.511140000000001e-05
metacluster_0/pattern_140.0382013
metacluster_0/pattern_160.00022232
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0385144
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_50.012318
metacluster_0/pattern_60.00218333
metacluster_0/pattern_70.0005354719999999999
metacluster_0/pattern_110.00557598
metacluster_0/pattern_140.0121125
metacluster_0/pattern_160.0191604
Absent
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_50.014026400000000001
metacluster_0/pattern_60.014566399999999998
metacluster_0/pattern_70.0191726
metacluster_0/pattern_106.16616e-12
metacluster_0/pattern_140.04231819999999999
metacluster_0/pattern_160.0498788
Absent
Zbtb14
Pattern NameModiscoSignificance
metacluster_0/pattern_60.030380900000000002
Absent
Tfap2b
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0490168
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00748804
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0574869
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0178365
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_50.0427255
metacluster_0/pattern_70.000268464
metacluster_0/pattern_160.00239282
Absent
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0382013
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_50.00344136
metacluster_0/pattern_60.00218333
metacluster_0/pattern_70.000731289
metacluster_0/pattern_110.00474658
metacluster_0/pattern_140.026680400000000003
metacluster_0/pattern_160.000904643
Absent
Mybl1
Pattern NameModiscoSignificance
metacluster_0/pattern_160.0109554
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_00.041231800000000006
metacluster_0/pattern_130.019630599999999998
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_82.39041e-06
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.037256300000000006
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_71.69189e-05
metacluster_0/pattern_160.00751272
Absent
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0456075
Absent
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0488065
Absent
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0488065
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.033948400000000004
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_140.010878200000000001
Absent
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_50.033891199999999996
metacluster_0/pattern_60.030380900000000002
metacluster_0/pattern_70.0216229
metacluster_0/pattern_101.4921799999999998e-07
metacluster_0/pattern_160.0564073
Absent
Nr1h4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0119973
metacluster_0/pattern_140.024172700000000002
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0410351
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0325144
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0392671
Absent
E2f6
Pattern NameModiscoSignificance
metacluster_0/pattern_160.047057
Absent
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000268464
metacluster_0/pattern_140.053951599999999995
metacluster_0/pattern_160.000742798
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.011826799999999998
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0121125
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00211126
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0206752
metacluster_0/pattern_70.05466569999999999
metacluster_0/pattern_160.0564073
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_80.022816299999999998
Absent
Irf6
Pattern NameModiscoSignificance
metacluster_0/pattern_160.0334594
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00347749
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_140.041755099999999996
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00106014
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_50.014026400000000001
metacluster_0/pattern_60.016277899999999998
metacluster_0/pattern_70.0053488
metacluster_0/pattern_80.0498281
metacluster_0/pattern_140.0047717
metacluster_0/pattern_160.0334594
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00386044
metacluster_0/pattern_50.00339711
metacluster_0/pattern_60.029433099999999997
metacluster_0/pattern_70.000268464
metacluster_0/pattern_140.0382013
metacluster_0/pattern_160.00223051
Absent
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0270385
Absent
Gmeb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.056139499999999995
Absent
Klf9
Pattern NameModiscoSignificance
metacluster_0/pattern_160.013706999999999999
Absent
Rxrg
Pattern NameModiscoSignificance
metacluster_0/pattern_140.0538275
Absent
E2f3
Pattern NameModiscoSignificance
metacluster_0/pattern_160.0444462
Absent
Unique Homer TFs: #5
TF NameModiscoHomer
SpicAbsent
Pattern NameHomerSignificance
motif3.motif0.0526008
Hes7Absent
Pattern NameHomerSignificance
motif8.motif0.0252135
Zbtb1Absent
Pattern NameHomerSignificance
motif1.motif0.0308367
Hes1Absent
Pattern NameHomerSignificance
motif8.motif0.036037599999999996
E2f7Absent
Pattern NameHomerSignificance
motif1.motif0.0438529