In [1]:
# Parameters
data_name = "aB;CD180;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_74-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_74-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:56:56,082 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeaBCD180
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1532213495113.03335518094448848330.088650144830.0909175065090.3174
    Modelling Metadata
    MetricValue
    auPRC0.6846
    Calibrated Recall at 50% FDR0.176
    Number of Positive Examples in Test Data44504
    Number of Negative Examples in Test Data8026347
    Imbalance Ratio in Test Data0.0055
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #20
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5858 SequenceContrib ScoresHyp_Contrib Scores
Spi1, Spib, Etv6, Ets1, Etv2, Etv4, Irf8, Irf4, Spic, Erg,

Fli1, Elk1, Gabpa, Etv3, XP_911724.4, Elf1, Elf4, Elk4, Ehf, Elf3, Elk3,

Elf2, Etv1, Etv5, Elf5, Fev, Irf3, Prdm1, Irf2, Spdef, Irf1
metacluster_1/pattern_1 # seqlets: 4561 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp3, Klf3, Sp1, Sp4, Zfx, Klf6, Klf1, Zbtb17, Egr1,

Wt1, Klf5, Klf15, Klf4, Klf7, Usf2, Zfp281, E2f4, Klf8, Klf12, Sp5,

Maz, Egr2, Mxi1, Ctcfl, Tfap2c, Nr1h4, Egr3, E2f1, Nhlh1, Rfx1, Sall4
metacluster_1/pattern_2 # seqlets: 3611 SequenceContrib ScoresHyp_Contrib Scores
Ctcf
metacluster_1/pattern_3 # seqlets: 1687 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Pbx3, Foxi1
metacluster_1/pattern_4 # seqlets: 1581 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_5 # seqlets: 1104 SequenceContrib ScoresHyp_Contrib Scores
Irf7, Stat2, Stat1, Irf9, Irf5, Irf6
metacluster_1/pattern_6 # seqlets: 1095 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Zfp42
metacluster_1/pattern_7 # seqlets: 760 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_8 # seqlets: 729 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf2, Atf7, Jdp2, Atf1, Crem, Creb5, Atf3, Usf1, Fosl2,

Hlf, Jun, Nfil3
metacluster_1/pattern_9 # seqlets: 489 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_10 # seqlets: 462 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2, Pou2f1, Pou5f1, Nanog
metacluster_1/pattern_11 # seqlets: 441 SequenceContrib ScoresHyp_Contrib Scores
Tfec, Tfeb, Mitf, Arntl, Srebf1, Tfe3, Bhlhe40, Mlx, Clock, Arnt,

Npas2, Srebf2, Tcfl5, Creb3l2, Bhlhe41, Dbp, Xbp1, Mlxip
metacluster_1/pattern_12 # seqlets: 377 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6, Sox2
metacluster_1/pattern_13 # seqlets: 349 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_14 # seqlets: 275 SequenceContrib ScoresHyp_Contrib Scores
Jund, Fos, Fosl1, Junb, Fosb, Batf, Bach2, Bach1, Nfe2, Nfe2l2,

Mafa
metacluster_1/pattern_15 # seqlets: 192 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 159 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2c, Mef2a
metacluster_1/pattern_17 # seqlets: 121 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_18 # seqlets: 92 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_19 # seqlets: 42 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib, Zfp322a
Click here for Motifs by TF-MoDISco: #151
TF NamePattern(s)
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000313337
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_02.0565e-05
metacluster_1/pattern_50.0043754
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000999498
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00023626400000000003
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_09.2045e-05
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000812731
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_09.31667e-05
metacluster_1/pattern_51.19648e-05
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_09.99925e-05
metacluster_1/pattern_50.00151798
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00033658099999999997
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000259922
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00182933
metacluster_1/pattern_10.018456599999999997
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000689055
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00828806
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000259922
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000259922
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000313337
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000376916
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00068904
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00151502
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00369784
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000689055
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.012806999999999999
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000999498
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00073609
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0110781
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00587304
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00591067
metacluster_1/pattern_50.04703
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00591367
metacluster_1/pattern_50.000489214
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00715218
metacluster_1/pattern_50.00321344
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00828806
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0114152
metacluster_1/pattern_53.8420900000000005e-07
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_17.48337e-17
metacluster_1/pattern_65.42272e-05
metacluster_1/pattern_170.00514551
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_19.00958e-12
metacluster_1/pattern_60.00052419
metacluster_1/pattern_170.00901676
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_11.0598699999999998e-09
metacluster_1/pattern_60.0362043
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0006364540000000001
metacluster_1/pattern_60.000226658
metacluster_1/pattern_170.0101177
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00147326
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00143491
metacluster_1/pattern_40.0300019
metacluster_1/pattern_60.00186447
metacluster_1/pattern_80.0100222
metacluster_1/pattern_170.00814194
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_11.8858700000000003e-06
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.026960900000000003
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00011157
metacluster_1/pattern_60.00717166
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0552155
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000345647
metacluster_1/pattern_60.0275969
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000571727
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000827618
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00143491
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00119132
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0012143
metacluster_1/pattern_60.056228499999999994
metacluster_1/pattern_81.402e-05
metacluster_1/pattern_110.00265696
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0020755
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00147326
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00166096
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00166096
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0025434999999999998
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00392689
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.052879300000000004
metacluster_1/pattern_60.0467235
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0113073
metacluster_1/pattern_60.0450285
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016503900000000002
metacluster_1/pattern_22.9005999999999997e-09
Tfap2c
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0213495
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0264125
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.038423900000000004
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0404779
Nhlh1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0409208
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.042192400000000005
metacluster_1/pattern_60.006327
metacluster_1/pattern_121.94925e-10
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0487091
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_24.01189e-12
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_38.31518e-15
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_37.98997e-11
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_31.15093e-09
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_32.4914700000000002e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_39.82599e-06
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_42.92643e-07
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00016773599999999998
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000489214
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000826319
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00111071
Irf5
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0112648
Irf6
Pattern NameModiscoSignificance
metacluster_1/pattern_50.04703
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_62.5033000000000002e-06
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_62.5033000000000002e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00717166
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_72.26307e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_73.4632699999999996e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_77.32785e-14
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00340987
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00391037
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00144641
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00153828
metacluster_1/pattern_140.00040809099999999997
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0243243
metacluster_1/pattern_110.0154535
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.017071
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0014835999999999998
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0403429
metacluster_1/pattern_147.50481e-05
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00841071
metacluster_1/pattern_110.00356277
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.020256299999999998
metacluster_1/pattern_140.000106108
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.03759559999999999
metacluster_1/pattern_110.0388385
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0436778
metacluster_1/pattern_140.0447264
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.057335199999999996
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_94.53349e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00018047400000000002
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000993982
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00128093
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0314835
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00207843
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0132981
Pou5f1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.047344300000000006
metacluster_1/pattern_120.059377099999999995
Nanog
Pattern NameModiscoSignificance
metacluster_1/pattern_100.05535369999999999
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00232069
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00105251
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00175726
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00489792
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00218662
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00246947
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00650207
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0207453
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0402049
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0346977
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00232069
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00312015
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00431453
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.050497900000000005
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_110.015091899999999998
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0373019
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0424205
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_110.047719199999999996
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000544795
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.018603799999999997
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_127.22053e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000310882
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0009571289999999999
Sox2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.059377099999999995
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00120259
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_134.54314e-05
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00037276400000000004
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00038144300000000003
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0403636
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0057748
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_141.2848800000000001e-05
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.047151599999999995
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.035517
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_144.16853e-05
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0290969
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00479571
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00865345
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.010271899999999999
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0123448
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.05626799999999999
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_169.83272e-09
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_166.10687e-08
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000147419
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_171.3198e-05
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_191.06506e-05
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_190.00207327
Zfp322a
Pattern NameModiscoSignificance
metacluster_1/pattern_190.0241087
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #78
TF NameModiscoHomer
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00369784
Pattern NameHomerSignificance
motif3.motif0.035432
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0132981
Pattern NameHomerSignificance
motif14.motif0.013282200000000001
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.052879300000000004
metacluster_1/pattern_60.0467235
Pattern NameHomerSignificance
motif1.motif0.0493223
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000313337
Pattern NameHomerSignificance
motif3.motif0.03242009999999999
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0114152
metacluster_1/pattern_53.8420900000000005e-07
Pattern NameHomerSignificance
motif6.motif0.000591499
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00018047400000000002
Pattern NameHomerSignificance
motif16.motif8.19549e-05
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000689055
Pattern NameHomerSignificance
motif3.motif0.000861068
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00147326
Pattern NameHomerSignificance
motif1.motif0.0249102
motif15.motif0.042546600000000004
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000259922
Pattern NameHomerSignificance
motif3.motif0.000243999
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00111071
Pattern NameHomerSignificance
motif6.motif0.00223433
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00166096
Pattern NameHomerSignificance
motif1.motif0.00149268
motif15.motif0.042546600000000004
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00591367
metacluster_1/pattern_50.000489214
Pattern NameHomerSignificance
motif6.motif0.00602282
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_62.5033000000000002e-06
Pattern NameHomerSignificance
motif13.motif0.00724627
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_37.98997e-11
Pattern NameHomerSignificance
motif4.motif2.4430299999999997e-08
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_62.5033000000000002e-06
Pattern NameHomerSignificance
motif13.motif2.9374e-05
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_09.2045e-05
Pattern NameHomerSignificance
motif3.motif0.00286131
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000259922
Pattern NameHomerSignificance
motif3.motif0.000129629
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0110781
Pattern NameHomerSignificance
motif3.motif0.00442487
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0552155
Pattern NameHomerSignificance
motif1.motif0.0199832
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00166096
Pattern NameHomerSignificance
motif1.motif0.0228049
motif15.motif0.0414079
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00151502
Pattern NameHomerSignificance
motif3.motif0.029619799999999998
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000313337
Pattern NameHomerSignificance
motif3.motif0.000861068
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_31.15093e-09
Pattern NameHomerSignificance
motif4.motif1.47107e-08
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_77.32785e-14
Pattern NameHomerSignificance
motif5.motif0.00010922
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_171.3198e-05
Pattern NameHomerSignificance
motif12.motif0.00033897800000000003
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00128093
Pattern NameHomerSignificance
motif16.motif0.00047268900000000004
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00715218
metacluster_1/pattern_50.00321344
Pattern NameHomerSignificance
motif6.motif0.00661721
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00591067
metacluster_1/pattern_50.04703
Pattern NameHomerSignificance
motif6.motif0.059662
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016503900000000002
metacluster_1/pattern_22.9005999999999997e-09
Pattern NameHomerSignificance
motif2.motif0.000631019
motif10.motif0.00755486
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000993982
Pattern NameHomerSignificance
motif16.motif0.000558578
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00023626400000000003
Pattern NameHomerSignificance
motif3.motif0.00014231200000000002
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0314835
Pattern NameHomerSignificance
motif16.motif0.033355800000000005
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00119132
Pattern NameHomerSignificance
motif1.motif0.000832328
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_09.31667e-05
metacluster_1/pattern_51.19648e-05
Pattern NameHomerSignificance
motif6.motif2.35479e-05
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_19.00958e-12
metacluster_1/pattern_60.00052419
metacluster_1/pattern_170.00901676
Pattern NameHomerSignificance
motif1.motif2.997e-05
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_39.82599e-06
Pattern NameHomerSignificance
motif4.motif9.86528e-07
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_11.8858700000000003e-06
Pattern NameHomerSignificance
motif1.motif0.000647122
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_24.01189e-12
Pattern NameHomerSignificance
motif2.motif0.00033964300000000004
motif10.motif0.0052853
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_11.0598699999999998e-09
metacluster_1/pattern_60.0362043
Pattern NameHomerSignificance
motif1.motif5.0986400000000004e-05
Irf6
Pattern NameModiscoSignificance
metacluster_1/pattern_50.04703
Pattern NameHomerSignificance
motif3.motif0.0485718
Irf5
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0112648
Pattern NameHomerSignificance
motif6.motif0.0241323
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_38.31518e-15
Pattern NameHomerSignificance
motif4.motif1.31641e-10
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_134.54314e-05
Pattern NameHomerSignificance
motif11.motif0.044437199999999996
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00016773599999999998
Pattern NameHomerSignificance
motif6.motif0.0374524
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00011157
metacluster_1/pattern_60.00717166
Pattern NameHomerSignificance
motif1.motif0.0285558
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_72.26307e-21
Pattern NameHomerSignificance
motif5.motif1.53047e-05
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0006364540000000001
metacluster_1/pattern_60.000226658
metacluster_1/pattern_170.0101177
Pattern NameHomerSignificance
motif1.motif0.00877971
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.012806999999999999
Pattern NameHomerSignificance
motif3.motif0.00379484
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_32.4914700000000002e-06
Pattern NameHomerSignificance
motif4.motif2.3272800000000002e-05
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00068904
Pattern NameHomerSignificance
motif3.motif4.3987200000000005e-05
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000999498
Pattern NameHomerSignificance
motif3.motif4.3987200000000005e-05
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000489214
Pattern NameHomerSignificance
motif6.motif0.00990708
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.026960900000000003
Pattern NameHomerSignificance
motif1.motif0.0512989
motif15.motif0.0408554
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00828806
Pattern NameHomerSignificance
motif3.motif0.00306192
motif6.motif0.059662
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00182933
metacluster_1/pattern_10.018456599999999997
Pattern NameHomerSignificance
motif3.motif0.000585094
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00587304
Pattern NameHomerSignificance
motif3.motif0.00442487
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_17.48337e-17
metacluster_1/pattern_65.42272e-05
metacluster_1/pattern_170.00514551
Pattern NameHomerSignificance
motif1.motif1.3331e-05
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000689055
Pattern NameHomerSignificance
motif3.motif0.000503021
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000812731
Pattern NameHomerSignificance
motif3.motif0.00195947
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00717166
Pattern NameHomerSignificance
motif13.motif0.00724627
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000999498
Pattern NameHomerSignificance
motif3.motif0.00569813
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_94.53349e-05
Pattern NameHomerSignificance
motif16.motif0.000218152
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000376916
Pattern NameHomerSignificance
motif3.motif0.00116622
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_09.99925e-05
metacluster_1/pattern_50.00151798
Pattern NameHomerSignificance
motif6.motif0.00301818
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000827618
Pattern NameHomerSignificance
motif1.motif0.053354099999999995
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00143491
metacluster_1/pattern_40.0300019
metacluster_1/pattern_60.00186447
metacluster_1/pattern_80.0100222
metacluster_1/pattern_170.00814194
Pattern NameHomerSignificance
motif1.motif0.0285558
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00143491
Pattern NameHomerSignificance
motif1.motif0.000731506
motif15.motif0.050230199999999996
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00828806
Pattern NameHomerSignificance
motif3.motif0.0422293
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_73.4632699999999996e-21
Pattern NameHomerSignificance
motif5.motif1.0638599999999998e-05
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00073609
Pattern NameHomerSignificance
motif3.motif0.00010349899999999999
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_42.92643e-07
Pattern NameHomerSignificance
motif7.motif0.00134307
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000571727
Pattern NameHomerSignificance
motif1.motif0.0228049
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00147326
Pattern NameHomerSignificance
motif1.motif0.0013591
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000259922
Pattern NameHomerSignificance
motif3.motif0.000198622
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_02.0565e-05
metacluster_1/pattern_50.0043754
Pattern NameHomerSignificance
motif3.motif0.035432
motif6.motif0.000698462
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000826319
Pattern NameHomerSignificance
motif6.motif0.037967400000000005
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00033658099999999997
Pattern NameHomerSignificance
motif3.motif0.0139345
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00207843
Pattern NameHomerSignificance
motif14.motif0.013282200000000001
Unique TF-MoDISco TFs: #73
TF NameModiscoHomer
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.050497900000000005
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0403429
metacluster_1/pattern_147.50481e-05
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0123448
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00841071
metacluster_1/pattern_110.00356277
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00038144300000000003
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00144641
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0014835999999999998
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0207453
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0012143
metacluster_1/pattern_60.056228499999999994
metacluster_1/pattern_81.402e-05
metacluster_1/pattern_110.00265696
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00105251
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00175726
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00120259
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_191.06506e-05
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00392689
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00340987
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.057335199999999996
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00431453
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0009571289999999999
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_166.10687e-08
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00232069
Absent
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0403636
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.010271899999999999
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.05626799999999999
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0057748
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.035517
Absent
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0264125
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00218662
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.020256299999999998
metacluster_1/pattern_140.000106108
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0290969
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.047151599999999995
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00232069
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_141.2848800000000001e-05
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.042192400000000005
metacluster_1/pattern_60.006327
metacluster_1/pattern_121.94925e-10
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_190.00207327
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00037276400000000004
Absent
Sox2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.059377099999999995
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00246947
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_144.16853e-05
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0025434999999999998
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0487091
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_110.047719199999999996
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.018603799999999997
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00865345
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00489792
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00153828
metacluster_1/pattern_140.00040809099999999997
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0243243
metacluster_1/pattern_110.0154535
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000544795
Absent
Zfp322a
Pattern NameModiscoSignificance
metacluster_1/pattern_190.0241087
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_110.015091899999999998
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_169.83272e-09
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0020755
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.03759559999999999
metacluster_1/pattern_110.0388385
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0424205
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0373019
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0346977
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00650207
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.038423900000000004
Absent
Tfap2c
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0213495
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0404779
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_127.22053e-05
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00391037
Absent
Nanog
Pattern NameModiscoSignificance
metacluster_1/pattern_100.05535369999999999
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00312015
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00479571
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0436778
metacluster_1/pattern_140.0447264
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000310882
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000345647
metacluster_1/pattern_60.0275969
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.017071
Absent
Pou5f1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.047344300000000006
metacluster_1/pattern_120.059377099999999995
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000147419
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0402049
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0113073
metacluster_1/pattern_60.0450285
Absent
Nhlh1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0409208
Absent
Unique Homer TFs: #0
TF NameModiscoHomer