In [1]:
# Parameters
data_name = "gamma_delta_TCR_M-S-;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_79-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_79-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:58:29,916 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typegamma delta TCR M/S -/-
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep170127474417.97376033389147942380.079549459560.082198879280.3297
    Modelling Metadata
    MetricValue
    auPRC0.6387
    Calibrated Recall at 50% FDR0.208
    Number of Positive Examples in Test Data49086
    Number of Negative Examples in Test Data8021765
    Imbalance Ratio in Test Data0.0061
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #19
Pattern NameTF Name(s)Modisco
metacluster_0/pattern_0 # seqlets: 4268 SequenceContrib ScoresHyp_Contrib Scores
Ets1, Erg, Fli1, Gabpa, Elk4, Elk1, Etv4, Etv2, Spi1, Etv5,

Elk3, Fev, Etv6, Elf2, Etv3, Etv1, XP_911724.4, Spib, Elf1, Ehf, Elf4,

Irf8, Elf5, Spic, Irf4, Elf3, Spdef, Zscan10
metacluster_0/pattern_1 # seqlets: 3625 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp4, Sp3, Klf3, Sp1, E2f4, Klf7, Klf4, Klf6, Klf8,

Klf12, Klf1, Egr1, Zbtb17, Egr2, E2f1, Klf5, Sp5, Zfp281, Zfx, Zfp740,

Egr3, Zbtb1, Sall4
metacluster_0/pattern_2 # seqlets: 1887 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_0/pattern_3 # seqlets: 1658 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Creb5, Jdp2, Atf7, Atf2, Atf1, Crem, Jun, Nfil3, Tef,

Mafb, Fosl1, Dbp, Atf3, Cebpb, Gmeb2, Hlf, Jund, Rxrb, Junb, Fosl2,

Cebpa, Gmeb1, Cebpd, Esr2, Cebpg
metacluster_0/pattern_4 # seqlets: 1543 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_0/pattern_5 # seqlets: 1415 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_0/pattern_6 # seqlets: 1390 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Irf7, Stat2, Prdm1, Irf9, Stat1, Irf5, Irf3, Irf6
metacluster_0/pattern_7 # seqlets: 1251 SequenceContrib ScoresHyp_Contrib Scores
Bach2, Fos, Nfe2l2, Fosb, Nfe2, Bach1, Batf, Mafa, Mafk
metacluster_0/pattern_8 # seqlets: 778 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_0/pattern_9 # seqlets: 756 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42, Rfx1, Mxi1, Wt1, Maz
metacluster_0/pattern_10 # seqlets: 645 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_0/pattern_11 # seqlets: 588 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Usf2, Tfeb, Tfec, Arntl, Mitf, Tfe3, Srebf1, Bhlhe40, Clock,

Mlx, Arnt, Npas2, Creb3l2, Srebf2, Tcfl5, Bhlhe41, Xbp1, Mycn, Max, Mlxip,

Hes1, Myc
metacluster_0/pattern_12 # seqlets: 470 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_13 # seqlets: 355 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6, Sox2, Pou5f1
metacluster_0/pattern_14 # seqlets: 260 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_0/pattern_15 # seqlets: 238 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_0/pattern_16 # seqlets: 208 SequenceContrib ScoresHyp_Contrib Scores
Nfkb1, Rela, Nfkb2, Relb, Rel
metacluster_0/pattern_17 # seqlets: 105 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_18 # seqlets: 71 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2c, Mef2a
Click here for Motifs by TF-MoDISco: #160
TF NamePattern(s)
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000916338
metacluster_0/pattern_170.05201569999999999
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0468068
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0565416
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0382588
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00107615
metacluster_0/pattern_170.0548784
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00103993
metacluster_0/pattern_170.032981
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0253238
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00010999700000000001
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0158558
metacluster_0/pattern_170.040179900000000005
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000310998
metacluster_0/pattern_170.00676012
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0147158
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000596853
metacluster_0/pattern_170.0337252
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00084836
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00714236
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00105959
metacluster_0/pattern_170.00821139
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00104303
Spib
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00107615
metacluster_0/pattern_60.00724626
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00172621
metacluster_0/pattern_170.04871930000000001
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00541035
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.004652600000000001
Irf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00629116
metacluster_0/pattern_66.0758900000000005e-05
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0182421
Spic
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0249481
Irf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00639634
metacluster_0/pattern_60.00111373
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0182421
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0189817
Zscan10
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0310666
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_14.31068e-06
metacluster_0/pattern_94.19985e-05
metacluster_0/pattern_170.00011463700000000001
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000991057
metacluster_0/pattern_90.0596035
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_18.55259e-06
metacluster_0/pattern_90.000904192
metacluster_0/pattern_170.00104257
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_11.3676300000000002e-05
metacluster_0/pattern_90.033249400000000005
metacluster_0/pattern_170.0120199
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000336682
metacluster_0/pattern_90.000468135
metacluster_0/pattern_170.00145441
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000414524
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000444524
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00995941
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00056231
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000768398
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0128984
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034110699999999994
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034110699999999994
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00526682
metacluster_0/pattern_90.012525
metacluster_0/pattern_170.0117851
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034018900000000005
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0110713
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.013818899999999999
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0168006
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0200102
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034110699999999994
metacluster_0/pattern_90.00209099
metacluster_0/pattern_150.00123172
metacluster_0/pattern_170.00296566
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_10.040279199999999994
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.041355300000000005
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0474621
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.05434119999999999
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_28.152039999999999e-07
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_22.62263e-05
metacluster_0/pattern_170.041569699999999994
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000180806
metacluster_0/pattern_110.0563374
metacluster_0/pattern_170.0337252
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_36.395109999999999e-05
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0006598060000000001
metacluster_0/pattern_70.000741296
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00013413700000000002
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000605951
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0322798
metacluster_0/pattern_110.0140817
metacluster_0/pattern_170.0337252
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0017234000000000001
metacluster_0/pattern_170.0549444
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0147642
metacluster_0/pattern_70.0450202
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00519285
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00746944
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0108089
metacluster_0/pattern_70.053335400000000005
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.015649299999999998
metacluster_0/pattern_70.0189621
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0223383
metacluster_0/pattern_110.0563374
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0338079
metacluster_0/pattern_70.000118207
Cebpb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0286144
Gmeb2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0232438
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_30.027474900000000003
metacluster_0/pattern_110.0588693
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_30.029168200000000002
metacluster_0/pattern_70.00228568
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.029168299999999998
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0322798
metacluster_0/pattern_70.0191181
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0338079
metacluster_0/pattern_70.0025122
Cebpa
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0338079
Gmeb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0429698
Cebpd
Pattern NameModiscoSignificance
metacluster_0/pattern_30.047366399999999996
Esr2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.05215790000000001
Cebpg
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0541345
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_41.129e-08
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_52.96621e-14
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_57.085189999999999e-13
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_55.04034e-11
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_54.77562e-07
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_52.88905e-06
Irf1
Pattern NameModiscoSignificance
metacluster_0/pattern_61.37282e-07
Irf2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000788773
Irf7
Pattern NameModiscoSignificance
metacluster_0/pattern_63.14269e-05
Stat2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000519342
Prdm1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000575079
Irf9
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000575079
Stat1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000788773
Irf5
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0110309
Irf3
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0519711
Irf6
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0436972
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_72.39363e-05
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_72.39363e-05
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000118207
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_78.53717e-05
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000118207
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000483955
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.015404399999999999
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_70.028227999999999996
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_70.057579099999999994
Runx1
Pattern NameModiscoSignificance
metacluster_0/pattern_89.941700000000001e-05
Runx2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00649926
Runx3
Pattern NameModiscoSignificance
metacluster_0/pattern_80.000633025
Cbfb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00237301
Gfi1b
Pattern NameModiscoSignificance
metacluster_0/pattern_80.041699599999999996
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_93.4705199999999998e-06
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_96.39697e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_90.011060500000000001
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0207134
metacluster_0/pattern_134.81577e-08
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0356149
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0356149
metacluster_0/pattern_170.0337252
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0401274
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_101.34854e-21
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_101.34854e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_102.30533e-13
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00147762
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00160418
metacluster_0/pattern_170.015193
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000931505
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00103738
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00698313
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000928195
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00138835
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00420093
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_110.013118799999999998
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0329567
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0140817
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0563374
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00185705
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0419394
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00468277
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00899297
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_110.019412400000000003
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0308709
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0545135
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_110.05964149999999999
Mlxip
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0545135
Hes1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0561446
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0563374
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00019345099999999997
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00148531
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_138.96129e-06
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000211836
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000431762
Sox2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0597121
Pou5f1
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0273158
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00660397
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_158.13371e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_0/pattern_160.000245065
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00047432800000000004
Nfkb2
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00047432800000000004
Relb
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00339861
Rel
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00470931
Mef2d
Pattern NameModiscoSignificance
metacluster_0/pattern_181.00665e-05
Mef2c
Pattern NameModiscoSignificance
metacluster_0/pattern_182.5727199999999997e-05
Mef2a
Pattern NameModiscoSignificance
metacluster_0/pattern_180.00204261
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #73
TF NameModiscoHomer
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00107615
metacluster_0/pattern_170.0548784
Pattern NameHomerSignificance
motif2.motif6.76845e-07
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0108089
metacluster_0/pattern_70.053335400000000005
Pattern NameHomerSignificance
motif11.motif0.0515992
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000118207
Pattern NameHomerSignificance
motif11.motif0.05634580000000001
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000118207
Pattern NameHomerSignificance
motif11.motif0.0578654
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_30.029168200000000002
metacluster_0/pattern_70.00228568
Pattern NameHomerSignificance
motif11.motif0.0476754
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0147158
Pattern NameHomerSignificance
motif2.motif3.8275900000000004e-05
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0338079
metacluster_0/pattern_70.000118207
Pattern NameHomerSignificance
motif11.motif0.0007611339999999999
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034110699999999994
Pattern NameHomerSignificance
motif1.motif0.025645499999999998
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0182421
Pattern NameHomerSignificance
motif2.motif0.0202675
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_41.129e-08
Pattern NameHomerSignificance
motif9.motif0.00158126
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00105959
metacluster_0/pattern_170.00821139
Pattern NameHomerSignificance
motif2.motif3.4188899999999997e-07
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_90.011060500000000001
Pattern NameHomerSignificance
motif15.motif0.0107875
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00010999700000000001
Pattern NameHomerSignificance
motif2.motif0.00130725
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_70.057579099999999994
Pattern NameHomerSignificance
motif11.motif0.05634580000000001
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000414524
Pattern NameHomerSignificance
motif1.motif0.00554987
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0565416
Pattern NameHomerSignificance
motif2.motif1.62302e-05
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00526682
metacluster_0/pattern_90.012525
metacluster_0/pattern_170.0117851
Pattern NameHomerSignificance
motif1.motif0.0158859
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_102.30533e-13
Pattern NameHomerSignificance
motif3.motif0.000994302
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_11.3676300000000002e-05
metacluster_0/pattern_90.033249400000000005
metacluster_0/pattern_170.0120199
Pattern NameHomerSignificance
motif1.motif3.27684e-05
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_101.34854e-21
Pattern NameHomerSignificance
motif3.motif0.000994302
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0474621
Pattern NameHomerSignificance
motif1.motif0.0389242
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.013818899999999999
Pattern NameHomerSignificance
motif1.motif0.00850841
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_101.34854e-21
Pattern NameHomerSignificance
motif3.motif0.000994302
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034110699999999994
Pattern NameHomerSignificance
motif1.motif0.013677600000000002
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_18.55259e-06
metacluster_0/pattern_90.000904192
metacluster_0/pattern_170.00104257
Pattern NameHomerSignificance
motif1.motif9.30505e-06
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00172621
metacluster_0/pattern_170.04871930000000001
Pattern NameHomerSignificance
motif2.motif0.00311125
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00104303
Pattern NameHomerSignificance
motif2.motif8.895559999999999e-05
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_72.39363e-05
Pattern NameHomerSignificance
motif11.motif0.0130345
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000768398
Pattern NameHomerSignificance
motif1.motif0.000447326
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000310998
metacluster_0/pattern_170.00676012
Pattern NameHomerSignificance
motif2.motif5.59549e-08
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0468068
Pattern NameHomerSignificance
motif2.motif1.04094e-06
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_55.04034e-11
Pattern NameHomerSignificance
motif4.motif3.5648699999999995e-06
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.015649299999999998
metacluster_0/pattern_70.0189621
Pattern NameHomerSignificance
motif11.motif3.54949e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_22.62263e-05
metacluster_0/pattern_170.041569699999999994
Pattern NameHomerSignificance
motif8.motif0.000274368
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00056231
Pattern NameHomerSignificance
motif1.motif0.00176435
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0189817
Pattern NameHomerSignificance
motif2.motif0.0405728
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.004652600000000001
Pattern NameHomerSignificance
motif2.motif0.00130018
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0338079
metacluster_0/pattern_70.0025122
Pattern NameHomerSignificance
motif11.motif0.000249674
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_93.4705199999999998e-06
Pattern NameHomerSignificance
motif15.motif0.000202056
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
Pattern NameHomerSignificance
motif2.motif3.8275900000000004e-05
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0182421
Pattern NameHomerSignificance
motif2.motif0.022936500000000002
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0128984
Pattern NameHomerSignificance
motif1.motif0.0153279
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_28.152039999999999e-07
Pattern NameHomerSignificance
motif8.motif3.72052e-05
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.015404399999999999
Pattern NameHomerSignificance
motif11.motif0.00509849
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0006598060000000001
metacluster_0/pattern_70.000741296
Pattern NameHomerSignificance
motif11.motif0.0360362
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0147642
metacluster_0/pattern_70.0450202
Pattern NameHomerSignificance
motif11.motif0.00010316399999999999
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_57.085189999999999e-13
Pattern NameHomerSignificance
motif4.motif5.193859999999999e-06
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0382588
Pattern NameHomerSignificance
motif2.motif0.00130725
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_54.77562e-07
Pattern NameHomerSignificance
motif4.motif0.00111083
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_72.39363e-05
Pattern NameHomerSignificance
motif11.motif0.00010697799999999999
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.00995941
Pattern NameHomerSignificance
motif1.motif0.0413421
Spic
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0249481
Pattern NameHomerSignificance
motif2.motif0.00448674
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_70.028227999999999996
Pattern NameHomerSignificance
motif11.motif0.0244541
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000916338
metacluster_0/pattern_170.05201569999999999
Pattern NameHomerSignificance
motif2.motif3.98007e-06
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0158558
metacluster_0/pattern_170.040179900000000005
Pattern NameHomerSignificance
motif2.motif0.038118599999999996
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0322798
metacluster_0/pattern_70.0191181
Pattern NameHomerSignificance
motif11.motif0.00240397
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00541035
Pattern NameHomerSignificance
motif2.motif0.00224741
Irf6
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0436972
Pattern NameHomerSignificance
motif2.motif0.0358153
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_14.31068e-06
metacluster_0/pattern_94.19985e-05
metacluster_0/pattern_170.00011463700000000001
Pattern NameHomerSignificance
motif1.motif9.30505e-06
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000596853
metacluster_0/pattern_170.0337252
Pattern NameHomerSignificance
motif2.motif0.00224741
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00103993
metacluster_0/pattern_170.032981
Pattern NameHomerSignificance
motif2.motif1.77955e-05
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_96.39697e-06
Pattern NameHomerSignificance
motif15.motif3.01994e-07
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_78.53717e-05
Pattern NameHomerSignificance
motif11.motif0.00240397
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000444524
Pattern NameHomerSignificance
motif1.motif0.000196949
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00084836
Pattern NameHomerSignificance
motif2.motif0.00441475
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000483955
Pattern NameHomerSignificance
motif11.motif0.032035400000000006
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_52.96621e-14
Pattern NameHomerSignificance
motif4.motif1.9603100000000002e-07
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000998049
metacluster_0/pattern_170.0253238
Pattern NameHomerSignificance
motif2.motif0.00197597
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_52.88905e-06
Pattern NameHomerSignificance
motif4.motif0.000266812
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000991057
metacluster_0/pattern_90.0596035
Pattern NameHomerSignificance
motif1.motif0.023512
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.000336682
metacluster_0/pattern_90.000468135
metacluster_0/pattern_170.00145441
Pattern NameHomerSignificance
motif1.motif0.013677600000000002
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0110713
Pattern NameHomerSignificance
motif1.motif0.0242275
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00714236
Pattern NameHomerSignificance
motif2.motif0.0211137
Unique TF-MoDISco TFs: #87
TF NameModiscoHomer
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00047432800000000004
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034018900000000005
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000605951
Absent
Rel
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00470931
Absent
Cebpb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0286144
Absent
Spib
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00107615
metacluster_0/pattern_60.00724626
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00138835
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000575079
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0419394
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_138.96129e-06
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0563374
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000575079
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0310666
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000211836
Absent
Esr2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.05215790000000001
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0519711
Absent
Gmeb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0429698
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0140817
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00420093
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_0/pattern_89.941700000000001e-05
Absent
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0017234000000000001
metacluster_0/pattern_170.0549444
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00649926
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00639634
metacluster_0/pattern_60.00111373
Absent
Pou5f1
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0273158
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00237301
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0356149
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000788773
Absent
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0401274
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000931505
Absent
Irf5
Pattern NameModiscoSignificance
metacluster_0/pattern_60.0110309
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0223383
metacluster_0/pattern_110.0563374
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_0/pattern_181.00665e-05
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_110.013118799999999998
Absent
Gfi1b
Pattern NameModiscoSignificance
metacluster_0/pattern_80.041699599999999996
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00148531
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00185705
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000431762
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0168006
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_110.000928195
Absent
Nfkb1
Pattern NameModiscoSignificance
metacluster_0/pattern_160.000245065
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_0/pattern_180.00204261
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00468277
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00660397
Absent
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00746944
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00013413700000000002
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0545135
Absent
Cebpg
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0541345
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0308709
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00519285
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_30.029168299999999998
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00629116
metacluster_0/pattern_66.0758900000000005e-05
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00160418
metacluster_0/pattern_170.015193
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0322798
metacluster_0/pattern_110.0140817
metacluster_0/pattern_170.0337252
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_36.395109999999999e-05
Absent
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0329567
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00019345099999999997
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0356149
metacluster_0/pattern_170.0337252
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_158.13371e-05
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_10.040279199999999994
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_0/pattern_61.37282e-07
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_10.0200102
Absent
Relb
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00339861
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00103738
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00147762
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0207134
metacluster_0/pattern_134.81577e-08
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00698313
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_10.034110699999999994
metacluster_0/pattern_90.00209099
metacluster_0/pattern_150.00123172
metacluster_0/pattern_170.00296566
Absent
Nfkb2
Pattern NameModiscoSignificance
metacluster_0/pattern_160.00047432800000000004
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_0/pattern_63.14269e-05
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000519342
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_10.05434119999999999
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_30.027474900000000003
metacluster_0/pattern_110.0588693
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.000180806
metacluster_0/pattern_110.0563374
metacluster_0/pattern_170.0337252
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_0/pattern_182.5727199999999997e-05
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0545135
Absent
Cebpd
Pattern NameModiscoSignificance
metacluster_0/pattern_30.047366399999999996
Absent
Sox2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0597121
Absent
Hes1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0561446
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_10.041355300000000005
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_110.019412400000000003
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_0/pattern_60.000788773
Absent
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0563374
Absent
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_110.05964149999999999
Absent
Cebpa
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0338079
Absent
Gmeb2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0232438
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_0/pattern_80.000633025
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00899297
Absent
Unique Homer TFs: #7
TF NameModiscoHomer
Zic2Absent
Pattern NameHomerSignificance
motif8.motif0.0351767
MafgAbsent
Pattern NameHomerSignificance
motif11.motif0.0460639
Klf15Absent
Pattern NameHomerSignificance
motif1.motif0.0413421
Zic3Absent
Pattern NameHomerSignificance
motif8.motif0.044691800000000004
Snai1Absent
Pattern NameHomerSignificance
motif8.motif0.00892111
E2f6Absent
Pattern NameHomerSignificance
motif1.motif0.0413318
MaffAbsent
Pattern NameHomerSignificance
motif11.motif0.05600599999999999