In [1]:
# Parameters
data_name = "Tfh;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_24-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_24-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:45:16,620 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeTfh (CD4+CD44+CXCR5+PD1+CD25-) WT
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1954467180911.54724853797088725930.182970633880.1456159614080.329
    Modelling Metadata
    MetricValue
    auPRC0.6169
    Calibrated Recall at 50% FDR0.201
    Number of Positive Examples in Test Data85301
    Number of Negative Examples in Test Data7985550
    Imbalance Ratio in Test Data0.0106
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #20
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 6244 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4461 SequenceContrib ScoresHyp_Contrib Scores
Ets1, Erg, Elk1, Gabpa, Fli1, Elk4, Etv2, Etv4, Etv5, Elk3,

Elf2, Spi1, Etv6, Elf1, Ehf, Spib, Fev, Etv1, Etv3, XP_911724.4, Elf3,

Elf4, Elf5, Irf8, Irf4, Ets2, Stat4, Spdef, Spic
metacluster_1/pattern_2 # seqlets: 4282 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Klf4, Egr1,

Klf8, Klf12, Klf1, Zbtb17, Egr2, E2f1, Sp5, Zfp281, Klf5, Zfx, Zfp740,

Egr3
metacluster_1/pattern_3 # seqlets: 1502 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_4 # seqlets: 1384 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1022 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Jdp2, Atf2, Atf7, Creb5, Atf3, Crem, Atf1, Mafb, Fosl2,

Fosl1, Nfil3, Jun, Tef, Hlf, Dbp, Creb3l2
metacluster_1/pattern_6 # seqlets: 844 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Prdm1, Irf7, Stat1, Irf3, Irf9, Batf3, Stat2
metacluster_1/pattern_7 # seqlets: 814 SequenceContrib ScoresHyp_Contrib Scores
Rfx1, Rfx2, Rfx3, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_8 # seqlets: 759 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_1/pattern_9 # seqlets: 660 SequenceContrib ScoresHyp_Contrib Scores
Hes1, Hes7
metacluster_1/pattern_10 # seqlets: 645 SequenceContrib ScoresHyp_Contrib Scores
Jund, Batf, Fos, Fosb, Junb, Bach2, Nfe2, Mafa, Bach1, Nfe2l2,

Mafk, Mafg, Maf, Maff
metacluster_1/pattern_11 # seqlets: 638 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Zfp42
metacluster_1/pattern_12 # seqlets: 560 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Usf2, Tfe3, Tfeb, Arntl, Tfec, Mitf, Clock, Bhlhe40, Arnt,

Srebf1, Mlx, Npas2, Srebf2, Tcfl5, Mycn, Max, Myc, Bhlhe41, Xbp1
metacluster_1/pattern_13 # seqlets: 518 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Cbfb, Runx3
metacluster_1/pattern_14 # seqlets: 395 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_15 # seqlets: 227 SequenceContrib ScoresHyp_Contrib Scores
Nfatc1
metacluster_1/pattern_16 # seqlets: 167 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2, Pou2f1
metacluster_1/pattern_17 # seqlets: 88 SequenceContrib ScoresHyp_Contrib Scores
Maz, Wt1, Klf15
metacluster_1/pattern_18 # seqlets: 83 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_19 # seqlets: 54 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib
Click here for Motifs by TF-MoDISco: #151
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_02.44409e-16
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_08.18313e-08
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00200728
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_170.0324485
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_170.0541832
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00266671
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_18.46907e-05
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_170.0282214
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0007490110000000001
metacluster_1/pattern_170.026193
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00200728
metacluster_1/pattern_170.0541832
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0135403
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.054662199999999994
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0017937
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00111098
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0158527
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_60.0055985
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00200728
metacluster_1/pattern_170.029920699999999998
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0021972
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0021972
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0289007
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00853147
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0379889
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0184028
metacluster_1/pattern_62.6482800000000003e-05
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021941400000000003
metacluster_1/pattern_60.047264099999999996
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0289007
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0289007
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0299308
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.030363400000000002
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00284814
metacluster_1/pattern_90.00835497
metacluster_1/pattern_170.039811900000000004
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_27.76425e-06
metacluster_1/pattern_30.052223
metacluster_1/pattern_90.00104247
metacluster_1/pattern_110.00021621799999999998
metacluster_1/pattern_173.3299499999999995e-05
metacluster_1/pattern_180.00377777
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_27.76425e-06
metacluster_1/pattern_90.00114709
metacluster_1/pattern_110.00255211
metacluster_1/pattern_170.000638398
metacluster_1/pattern_180.00753187
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_23.6430700000000003e-05
metacluster_1/pattern_90.00104247
metacluster_1/pattern_170.00447151
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00122435
metacluster_1/pattern_90.0049817
metacluster_1/pattern_110.000568409
metacluster_1/pattern_170.00227121
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008098
metacluster_1/pattern_90.00904012
metacluster_1/pattern_170.000638398
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00122435
metacluster_1/pattern_90.00825571
metacluster_1/pattern_170.0123445
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00122435
metacluster_1/pattern_90.00104247
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0203713
metacluster_1/pattern_90.00904012
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.043682099999999995
metacluster_1/pattern_90.0289086
metacluster_1/pattern_170.027294299999999997
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00185165
metacluster_1/pattern_90.00114709
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025359
metacluster_1/pattern_90.00144874
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0247943
metacluster_1/pattern_90.00784686
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00426022
metacluster_1/pattern_110.0157893
metacluster_1/pattern_170.00545706
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0414046
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0158489
metacluster_1/pattern_170.027294299999999997
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0162386
metacluster_1/pattern_170.00166312
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025359
metacluster_1/pattern_90.00921384
metacluster_1/pattern_170.0446385
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0247943
metacluster_1/pattern_170.0286481
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025359
metacluster_1/pattern_30.0314946
metacluster_1/pattern_110.00389249
metacluster_1/pattern_170.026193
metacluster_1/pattern_180.00377777
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.042894699999999994
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.042894699999999994
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_37.764289999999999e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_43.43819e-14
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_44.2758100000000005e-13
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_41.43939e-11
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.19389e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_43.3706300000000004e-06
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00116907
metacluster_1/pattern_120.0285983
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00012230299999999998
metacluster_1/pattern_101.9553e-06
metacluster_1/pattern_120.021475599999999997
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00020470200000000002
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_57.94916e-05
metacluster_1/pattern_120.0521972
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_55.67591e-05
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00530069
metacluster_1/pattern_100.0007590539999999999
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00139815
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0162153
metacluster_1/pattern_120.027780400000000004
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00336826
metacluster_1/pattern_100.027179000000000002
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00445871
metacluster_1/pattern_100.000176684
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00618172
metacluster_1/pattern_100.00585491
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00828448
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0362388
metacluster_1/pattern_100.046643800000000006
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0162153
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0324902
metacluster_1/pattern_120.021475599999999997
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_50.050301599999999995
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.050301599999999995
metacluster_1/pattern_120.028758699999999998
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_62.17087e-15
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0017457999999999998
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_68.572440000000001e-05
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00016342
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00016979700000000001
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0017457999999999998
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0017457999999999998
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00205562
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00321668
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_73.48932e-07
metacluster_1/pattern_110.0352666
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_75.380640000000001e-08
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0128226
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_74.904e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00567274
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_70.012552200000000001
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_86.46319e-22
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_89.34908e-22
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_81.2995e-13
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0430006
Hes7
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0430006
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00230321
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0166988
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_105.33262e-05
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00032177299999999997
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00998859
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00642711
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00893317
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00912087
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00957012
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.010628299999999999
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_100.013455799999999999
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_100.027179000000000002
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.030817700000000003
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0407906
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_113.3599599999999998e-06
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_114.41481e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0157893
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0180655
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00837649
metacluster_1/pattern_170.0390304
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0010714000000000001
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000300494
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00756314
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00110355
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000736985
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0185138
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.014296000000000001
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0485109
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0356346
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00908027
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00255052
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00700271
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0144048
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0180655
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.021475599999999997
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.028758699999999998
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0270057
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.053748500000000005
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00545241
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00326714
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00353378
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00545241
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_142.69747e-06
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_148.100119999999999e-05
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000564808
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000530716
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0279224
Nfatc1
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0219297
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00455992
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.021396000000000002
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00166312
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00227121
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0137565
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_181.59597e-06
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_190.00553457
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_190.021386900000000004
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #76
TF NameModiscoHomer
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0135403
Pattern NameHomerSignificance
motif3.motif0.0334586
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00200728
metacluster_1/pattern_170.0541832
Pattern NameHomerSignificance
motif3.motif0.000376095
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0158489
metacluster_1/pattern_170.027294299999999997
Pattern NameHomerSignificance
motif2.motif0.00456272
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_89.34908e-22
Pattern NameHomerSignificance
motif5.motif1.0224700000000002e-06
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00530069
metacluster_1/pattern_100.0007590539999999999
Pattern NameHomerSignificance
motif6.motif0.047319099999999996
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000530716
Pattern NameHomerSignificance
motif18.motif0.0145077
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_57.94916e-05
metacluster_1/pattern_120.0521972
Pattern NameHomerSignificance
motif6.motif0.0105059
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0017457999999999998
Pattern NameHomerSignificance
motif20.motif0.0232606
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_02.44409e-16
Pattern NameHomerSignificance
motif1.motif0.000473677
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0247943
metacluster_1/pattern_170.0286481
Pattern NameHomerSignificance
motif2.motif0.00588086
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00266671
Pattern NameHomerSignificance
motif3.motif0.00034050300000000003
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_62.17087e-15
Pattern NameHomerSignificance
motif20.motif0.0241909
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0203713
metacluster_1/pattern_90.00904012
Pattern NameHomerSignificance
motif2.motif0.014273
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_18.46907e-05
Pattern NameHomerSignificance
motif3.motif0.00209395
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
Pattern NameHomerSignificance
motif3.motif0.00869049
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_68.572440000000001e-05
Pattern NameHomerSignificance
motif20.motif0.022565900000000003
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
Pattern NameHomerSignificance
motif3.motif0.00159988
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00116907
metacluster_1/pattern_120.0285983
Pattern NameHomerSignificance
motif6.motif0.047319099999999996
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00445871
metacluster_1/pattern_100.000176684
Pattern NameHomerSignificance
motif6.motif0.0412636
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.043682099999999995
metacluster_1/pattern_90.0289086
metacluster_1/pattern_170.027294299999999997
Pattern NameHomerSignificance
motif2.motif0.00588086
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00122435
metacluster_1/pattern_90.00825571
metacluster_1/pattern_170.0123445
Pattern NameHomerSignificance
motif2.motif0.00207336
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_27.76425e-06
metacluster_1/pattern_30.052223
metacluster_1/pattern_90.00104247
metacluster_1/pattern_110.00021621799999999998
metacluster_1/pattern_173.3299499999999995e-05
metacluster_1/pattern_180.00377777
Pattern NameHomerSignificance
motif2.motif0.00226368
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00012230299999999998
metacluster_1/pattern_101.9553e-06
metacluster_1/pattern_120.021475599999999997
Pattern NameHomerSignificance
motif6.motif0.0412636
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_60.0055985
Pattern NameHomerSignificance
motif20.motif0.0232606
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.19389e-06
Pattern NameHomerSignificance
motif7.motif8.83573e-06
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_37.764289999999999e-07
Pattern NameHomerSignificance
motif10.motif3.64576e-07
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_41.43939e-11
Pattern NameHomerSignificance
motif7.motif1.26964e-06
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0137565
Pattern NameHomerSignificance
motif2.motif0.00588086
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00122435
metacluster_1/pattern_90.0049817
metacluster_1/pattern_110.000568409
metacluster_1/pattern_170.00227121
Pattern NameHomerSignificance
motif2.motif0.00843207
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0289007
Pattern NameHomerSignificance
motif3.motif0.0350235
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_113.3599599999999998e-06
Pattern NameHomerSignificance
motif13.motif0.015128200000000001
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0414046
Pattern NameHomerSignificance
motif2.motif0.0457586
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_08.18313e-08
Pattern NameHomerSignificance
motif1.motif0.0008640119999999999
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.030363400000000002
Pattern NameHomerSignificance
motif3.motif0.0164261
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00016342
Pattern NameHomerSignificance
motif20.motif0.0490115
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00426022
metacluster_1/pattern_110.0157893
metacluster_1/pattern_170.00545706
Pattern NameHomerSignificance
motif2.motif0.0107851
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000564808
Pattern NameHomerSignificance
motif18.motif0.0145077
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_23.6430700000000003e-05
metacluster_1/pattern_90.00104247
metacluster_1/pattern_170.00447151
Pattern NameHomerSignificance
motif2.motif0.00032108099999999997
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0247943
metacluster_1/pattern_90.00784686
Pattern NameHomerSignificance
motif2.motif0.046199300000000006
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00200728
metacluster_1/pattern_170.029920699999999998
Pattern NameHomerSignificance
motif3.motif0.000110163
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008098
metacluster_1/pattern_90.00904012
metacluster_1/pattern_170.000638398
Pattern NameHomerSignificance
motif2.motif0.00110777
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_43.43819e-14
Pattern NameHomerSignificance
motif7.motif4.88037e-10
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00139815
Pattern NameHomerSignificance
motif6.motif0.014537600000000001
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0184028
metacluster_1/pattern_62.6482800000000003e-05
Pattern NameHomerSignificance
motif20.motif0.0232606
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00284814
metacluster_1/pattern_90.00835497
metacluster_1/pattern_170.039811900000000004
Pattern NameHomerSignificance
motif2.motif0.00638864
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025359
metacluster_1/pattern_90.00144874
Pattern NameHomerSignificance
motif2.motif0.016310599999999998
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.054662199999999994
Pattern NameHomerSignificance
motif3.motif0.0164261
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00020470200000000002
Pattern NameHomerSignificance
motif6.motif0.0156763
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00336826
metacluster_1/pattern_100.027179000000000002
Pattern NameHomerSignificance
motif6.motif0.0348645
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0007490110000000001
metacluster_1/pattern_170.026193
Pattern NameHomerSignificance
motif3.motif5.18381e-06
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0017937
Pattern NameHomerSignificance
motif3.motif0.00869135
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_81.2995e-13
Pattern NameHomerSignificance
motif5.motif2.26498e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_148.100119999999999e-05
Pattern NameHomerSignificance
motif18.motif0.00975195
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_43.3706300000000004e-06
Pattern NameHomerSignificance
motif7.motif0.000100354
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0158527
Pattern NameHomerSignificance
motif3.motif0.014687100000000002
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_114.41481e-06
Pattern NameHomerSignificance
motif13.motif0.001515
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_170.0282214
Pattern NameHomerSignificance
motif3.motif0.00389574
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_27.76425e-06
metacluster_1/pattern_90.00114709
metacluster_1/pattern_110.00255211
metacluster_1/pattern_170.000638398
metacluster_1/pattern_180.00753187
Pattern NameHomerSignificance
motif2.motif0.00208449
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00122435
metacluster_1/pattern_90.00104247
Pattern NameHomerSignificance
motif2.motif6.75808e-05
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_170.0541832
Pattern NameHomerSignificance
motif3.motif0.00167258
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00853147
Pattern NameHomerSignificance
motif3.motif6.0121099999999996e-05
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0299308
Pattern NameHomerSignificance
motif3.motif0.00280736
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_55.67591e-05
Pattern NameHomerSignificance
motif6.motif0.00540424
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_86.46319e-22
Pattern NameHomerSignificance
motif5.motif6.26329e-07
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00185165
metacluster_1/pattern_90.00114709
Pattern NameHomerSignificance
motif2.motif8.00764e-05
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
metacluster_1/pattern_170.0324485
Pattern NameHomerSignificance
motif3.motif0.00457163
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0021972
Pattern NameHomerSignificance
motif3.motif1.26214e-05
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0162153
metacluster_1/pattern_120.027780400000000004
Pattern NameHomerSignificance
motif6.motif0.0412636
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0162386
metacluster_1/pattern_170.00166312
Pattern NameHomerSignificance
motif2.motif0.0145091
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00111098
Pattern NameHomerSignificance
motif3.motif0.000492466
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00200728
Pattern NameHomerSignificance
motif3.motif0.000412241
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00196967
Pattern NameHomerSignificance
motif3.motif0.00066345
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0021972
Pattern NameHomerSignificance
motif3.motif9.635639999999999e-06
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_142.69747e-06
Pattern NameHomerSignificance
motif18.motif0.00975195
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0379889
Pattern NameHomerSignificance
motif3.motif0.00135627
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_44.2758100000000005e-13
Pattern NameHomerSignificance
motif7.motif2.07736e-06
Unique TF-MoDISco TFs: #75
TF NameModiscoHomer
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00908027
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000300494
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00255052
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_50.050301599999999995
Absent
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0430006
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0166988
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00642711
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00230321
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.021475599999999997
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00205562
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00032177299999999997
Absent
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0289007
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0270057
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00912087
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0279224
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.042894699999999994
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_105.33262e-05
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0017457999999999998
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0356346
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0010714000000000001
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0362388
metacluster_1/pattern_100.046643800000000006
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00326714
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.050301599999999995
metacluster_1/pattern_120.028758699999999998
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.053748500000000005
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.010628299999999999
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00567274
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00110355
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.014296000000000001
Absent
Nfatc1
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0219297
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00227121
Absent
Hes7
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0430006
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_190.021386900000000004
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0180655
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0180655
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00837649
metacluster_1/pattern_170.0390304
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0162153
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00321668
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_73.48932e-07
metacluster_1/pattern_110.0352666
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00545241
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0144048
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0324902
metacluster_1/pattern_120.021475599999999997
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00957012
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.021941400000000003
metacluster_1/pattern_60.047264099999999996
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00545241
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00455992
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00166312
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000736985
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0128226
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00353378
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00756314
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_181.59597e-06
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00700271
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0017457999999999998
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_190.00553457
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.030817700000000003
Absent
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.021396000000000002
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0289007
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.042894699999999994
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00828448
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_74.904e-05
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0485109
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00016979700000000001
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0157893
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00893317
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_75.380640000000001e-08
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0185138
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_100.027179000000000002
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00998859
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_70.012552200000000001
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025359
metacluster_1/pattern_30.0314946
metacluster_1/pattern_110.00389249
metacluster_1/pattern_170.026193
metacluster_1/pattern_180.00377777
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00618172
metacluster_1/pattern_100.00585491
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.028758699999999998
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025359
metacluster_1/pattern_90.00921384
metacluster_1/pattern_170.0446385
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_100.013455799999999999
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0407906
Absent
Unique Homer TFs: #3
TF NameModiscoHomer
E2f6Absent
Pattern NameHomerSignificance
motif2.motif0.043524400000000005
Zbtb1Absent
Pattern NameHomerSignificance
motif2.motif0.051669900000000005
E2f7Absent
Pattern NameHomerSignificance
motif2.motif0.0100191