In [1]:
# Parameters
data_name = "aB_LPS;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_13-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_13-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:41:46,047 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeaB LPS
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1559593608913.67354634102445656950.098646697320.1008148931390.3215
    Modelling Metadata
    MetricValue
    auPRC0.6772
    Calibrated Recall at 50% FDR0.168
    Number of Positive Examples in Test Data45734
    Number of Negative Examples in Test Data8025117
    Imbalance Ratio in Test Data0.0057
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #19
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5161 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 5014 SequenceContrib ScoresHyp_Contrib Scores
Spib, Spi1, Irf8, Irf4, Ets1, Etv6, Erg, Gabpa, Elk1, Etv2,

Spic, Elf1, Etv3, Ehf, Elf3, Fli1, XP_911724.4, Etv4, Elf4, Elk4, Elk3,

Elf2, Etv5, Etv1, Prdm1, Irf3, Elf5, Irf2, Irf1, Fev, Spdef
metacluster_1/pattern_2 # seqlets: 3685 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp3, Sp4, Sp1, Klf3, Klf4, E2f4, Klf6, Egr1, Klf7,

Sp5, Zbtb17, Klf8, Klf5, Klf12, Egr2, Wt1, Klf1, Zfp281, Maz, E2f1,

Klf15, Egr3, Srebf2, Zfp740
metacluster_1/pattern_3 # seqlets: 1960 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_4 # seqlets: 1878 SequenceContrib ScoresHyp_Contrib Scores
Nrf1, Zfx
metacluster_1/pattern_5 # seqlets: 1366 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Zfp42, Rfx1, Mxi1
metacluster_1/pattern_6 # seqlets: 1036 SequenceContrib ScoresHyp_Contrib Scores
Stat2, Irf7, Zscan10, Stat1, Irf9
metacluster_1/pattern_7 # seqlets: 973 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_8 # seqlets: 797 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Usf2, Atf2, Jdp2, Atf7, Atf1, Crem, Creb5, Atf3, Fosl2,

Usf1, Jun, Hlf, Fosl1, Nfil3, Rxrb, Tef
metacluster_1/pattern_9 # seqlets: 480 SequenceContrib ScoresHyp_Contrib Scores
Tfe3, Tfeb, Arntl, Tfec, Mitf, Clock, Bhlhe40, Srebf1, Arnt, Mlx,

Npas2, Tcfl5, Bhlhe41, Creb3l2, Mycn, Max, Rxrg, Myc
metacluster_1/pattern_10 # seqlets: 422 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_1/pattern_11 # seqlets: 349 SequenceContrib ScoresHyp_Contrib Scores
Fos, Jund, Batf, Fosb, Junb, Bach2, Nfe2, Nfe2l2, Bach1, Mafk,

Mafa, Mafb, Mafg, Maff, Maf
metacluster_1/pattern_12 # seqlets: 221 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_13 # seqlets: 190 SequenceContrib ScoresHyp_Contrib Scores
Nfkb1, Rela, Relb, Nfkb2, Rel
metacluster_1/pattern_14 # seqlets: 161 SequenceContrib ScoresHyp_Contrib Scores
Rfx2, Rfx3, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_15 # seqlets: 107 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 101 SequenceContrib ScoresHyp_Contrib Scores
Ebf1, Prdm16
metacluster_1/pattern_17 # seqlets: 79 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2a, Mef2c
metacluster_1/pattern_18 # seqlets: 72 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #145
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_04.52188e-13
metacluster_1/pattern_140.019318400000000003
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_07.36031e-08
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_18.581619999999999e-07
metacluster_1/pattern_64.6927100000000005e-07
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00029711799999999997
metacluster_1/pattern_60.0043186000000000006
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_15.12594e-05
metacluster_1/pattern_62.42169e-13
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_15.86255e-05
metacluster_1/pattern_60.0257478
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000287689
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00202921
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00029711799999999997
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00206096
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000289767
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019558099999999998
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000303585
metacluster_1/pattern_60.0269061
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000289767
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000289767
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00211231
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00546408
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0014976
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000373089
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00109868
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000452635
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000676143
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000873813
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00503099
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0009373119999999999
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00118397
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00129449
metacluster_1/pattern_60.0106874
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00206099
metacluster_1/pattern_60.00335088
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00510603
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00266291
metacluster_1/pattern_60.0277231
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00463559
metacluster_1/pattern_64.08184e-05
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00947563
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.011977400000000001
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_24.74506e-08
metacluster_1/pattern_50.0579114
metacluster_1/pattern_80.00670178
metacluster_1/pattern_90.0249495
metacluster_1/pattern_140.00010439200000000001
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.7843800000000003e-07
metacluster_1/pattern_50.0564028
metacluster_1/pattern_140.00115363
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0011937999999999999
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000347592
metacluster_1/pattern_80.0234554
metacluster_1/pattern_140.00036118900000000004
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_25.16084e-07
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0009016810000000001
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000347592
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000595334
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0127809
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000698033
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008950680000000001
metacluster_1/pattern_140.0444123
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008950680000000001
metacluster_1/pattern_140.0372437
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00108118
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00112944
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00112944
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0348614
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00237952
metacluster_1/pattern_140.02615
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0176273
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00510968
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0101992
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.021005700000000002
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0274089
metacluster_1/pattern_140.0584347
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.038108300000000005
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.050438199999999996
metacluster_1/pattern_90.00433468
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.050438199999999996
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_33.29772e-10
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_35.26455e-06
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_35.26455e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_35.26455e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_39.57188e-05
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_42.3915199999999997e-07
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0496577
metacluster_1/pattern_80.0110316
metacluster_1/pattern_90.0230801
metacluster_1/pattern_140.00169359
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.8070400000000002e-06
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.8070400000000002e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0263144
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0579114
metacluster_1/pattern_80.018947400000000003
metacluster_1/pattern_147.10015e-10
metacluster_1/pattern_150.009836399999999999
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0599947
metacluster_1/pattern_90.00376182
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.006857899999999999
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00827274
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00879301
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.016779
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0191863
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_72.64438e-23
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_76.2699e-22
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_74.47152e-14
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00173594
metacluster_1/pattern_90.033969
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_88.216040000000001e-05
metacluster_1/pattern_90.0132664
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00100785
metacluster_1/pattern_90.023859599999999998
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000336156
metacluster_1/pattern_90.0575856
metacluster_1/pattern_117.61672e-05
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00032057900000000004
metacluster_1/pattern_90.0147732
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.014066200000000001
metacluster_1/pattern_90.0302808
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00548929
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00102718
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00303227
metacluster_1/pattern_112.79975e-05
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00722354
metacluster_1/pattern_115.773480000000001e-06
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.017734299999999998
metacluster_1/pattern_90.0147732
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0205123
metacluster_1/pattern_110.052644500000000004
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0224365
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0232333
metacluster_1/pattern_110.037157199999999994
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026734699999999997
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0330006
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_80.047769099999999995
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0032341
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000591916
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_90.010312200000000002
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00368969
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00161281
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0006178630000000001
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00874067
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0570211
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0426028
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0163645
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00368969
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0113485
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0174873
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0244475
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_90.033969
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0402931
Rxrg
Pattern NameModiscoSignificance
metacluster_1/pattern_90.041020999999999995
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0575856
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.006988600000000001
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_114.88925e-06
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00852195
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00669665
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_111.7368499999999998e-05
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0462094
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_117.61672e-05
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000175938
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00018904099999999998
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00025983
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00432366
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00809606
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0114259
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.011947200000000002
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0158607
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.018482
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_124.5438e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_139.32012e-05
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00017994200000000002
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00017994200000000002
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00017994200000000002
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00128815
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_141.5087799999999998e-09
metacluster_1/pattern_150.017316400000000003
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00355378
metacluster_1/pattern_150.00151811
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00036118900000000004
metacluster_1/pattern_150.017316400000000003
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00226825
metacluster_1/pattern_150.00746146
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00554573
metacluster_1/pattern_150.00151811
Ebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00968029
Prdm16
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0183117
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_174.2770399999999995e-09
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000307572
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_172.64104e-08
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #63
TF NameModiscoHomer
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00109868
Pattern NameHomerSignificance
motif3.motif0.00199287
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_35.26455e-06
Pattern NameHomerSignificance
motif4.motif0.00148169
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00112944
Pattern NameHomerSignificance
motif2.motif0.00907928
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000289767
Pattern NameHomerSignificance
motif3.motif0.00056847
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0127809
Pattern NameHomerSignificance
motif2.motif0.0100604
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_24.74506e-08
metacluster_1/pattern_50.0579114
metacluster_1/pattern_80.00670178
metacluster_1/pattern_90.0249495
metacluster_1/pattern_140.00010439200000000001
Pattern NameHomerSignificance
motif2.motif7.66404e-05
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_124.5438e-05
Pattern NameHomerSignificance
motif9.motif0.00106941
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_04.52188e-13
metacluster_1/pattern_140.019318400000000003
Pattern NameHomerSignificance
motif1.motif1.23463e-06
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_139.32012e-05
Pattern NameHomerSignificance
motif15.motif0.021300799999999998
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00202921
Pattern NameHomerSignificance
motif3.motif0.00457979
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000676143
Pattern NameHomerSignificance
motif3.motif0.000365574
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0009016810000000001
Pattern NameHomerSignificance
motif2.motif0.0318201
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0009373119999999999
Pattern NameHomerSignificance
motif3.motif1.5838699999999998e-05
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00510603
Pattern NameHomerSignificance
motif3.motif0.00137435
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.011977400000000001
Pattern NameHomerSignificance
motif3.motif0.011654000000000001
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00017994200000000002
Pattern NameHomerSignificance
motif14.motif0.029232099999999997
motif15.motif0.0263385
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_07.36031e-08
Pattern NameHomerSignificance
motif1.motif0.000150441
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00019558099999999998
Pattern NameHomerSignificance
motif3.motif0.0029376
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00206096
Pattern NameHomerSignificance
motif3.motif0.0050605
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00108118
Pattern NameHomerSignificance
motif2.motif0.000424515
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00947563
Pattern NameHomerSignificance
motif3.motif0.0132854
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_39.57188e-05
Pattern NameHomerSignificance
motif4.motif0.000415985
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00112944
Pattern NameHomerSignificance
motif2.motif0.00687749
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000347592
metacluster_1/pattern_80.0234554
metacluster_1/pattern_140.00036118900000000004
Pattern NameHomerSignificance
motif2.motif0.00808557
motif14.motif0.0296094
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000873813
Pattern NameHomerSignificance
motif3.motif0.000478935
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00237952
metacluster_1/pattern_140.02615
Pattern NameHomerSignificance
motif14.motif0.029232099999999997
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000347592
Pattern NameHomerSignificance
motif2.motif0.00061806
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000595334
Pattern NameHomerSignificance
motif2.motif0.0007423880000000001
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_15.12594e-05
metacluster_1/pattern_62.42169e-13
Pattern NameHomerSignificance
motif3.motif0.032167799999999996
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.7843800000000003e-07
metacluster_1/pattern_50.0564028
metacluster_1/pattern_140.00115363
Pattern NameHomerSignificance
motif2.motif9.77634e-05
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.021005700000000002
Pattern NameHomerSignificance
motif2.motif0.05904349999999999
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00510968
Pattern NameHomerSignificance
motif14.motif0.0456068
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00503099
Pattern NameHomerSignificance
motif3.motif0.0144172
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_35.26455e-06
Pattern NameHomerSignificance
motif4.motif2.80642e-06
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00017994200000000002
Pattern NameHomerSignificance
motif15.motif0.021300799999999998
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000287689
Pattern NameHomerSignificance
motif3.motif0.000672729
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0011937999999999999
Pattern NameHomerSignificance
motif2.motif0.024109000000000002
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000373089
Pattern NameHomerSignificance
motif3.motif4.81125e-05
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00211231
Pattern NameHomerSignificance
motif3.motif0.0144172
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00017994200000000002
Pattern NameHomerSignificance
motif15.motif0.0496454
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_74.47152e-14
Pattern NameHomerSignificance
motif5.motif5.2806e-05
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_76.2699e-22
Pattern NameHomerSignificance
motif5.motif4.41944e-07
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_18.581619999999999e-07
metacluster_1/pattern_64.6927100000000005e-07
Pattern NameHomerSignificance
motif3.motif0.0132854
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00118397
Pattern NameHomerSignificance
motif3.motif7.49369e-05
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00029711799999999997
Pattern NameHomerSignificance
motif3.motif0.00059431
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0014976
Pattern NameHomerSignificance
motif3.motif0.00111217
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_72.64438e-23
Pattern NameHomerSignificance
motif5.motif4.41944e-07
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000289767
Pattern NameHomerSignificance
motif3.motif0.000478935
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0348614
Pattern NameHomerSignificance
motif2.motif0.044981
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000698033
Pattern NameHomerSignificance
motif2.motif0.00016804099999999999
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0176273
Pattern NameHomerSignificance
motif2.motif0.0212485
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000303585
metacluster_1/pattern_60.0269061
Pattern NameHomerSignificance
motif3.motif0.00348613
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00173594
metacluster_1/pattern_90.033969
Pattern NameHomerSignificance
motif7.motif0.00404498
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_33.29772e-10
Pattern NameHomerSignificance
motif4.motif1.08247e-07
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00029711799999999997
metacluster_1/pattern_60.0043186000000000006
Pattern NameHomerSignificance
motif3.motif0.026806
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000289767
Pattern NameHomerSignificance
motif3.motif4.60931e-05
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000452635
Pattern NameHomerSignificance
motif3.motif9.40234e-05
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_15.86255e-05
metacluster_1/pattern_60.0257478
Pattern NameHomerSignificance
motif3.motif0.0286072
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_35.26455e-06
Pattern NameHomerSignificance
motif4.motif5.60247e-06
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008950680000000001
metacluster_1/pattern_140.0444123
Pattern NameHomerSignificance
motif14.motif0.029232099999999997
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_25.16084e-07
Pattern NameHomerSignificance
motif2.motif7.66404e-05
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_42.3915199999999997e-07
Pattern NameHomerSignificance
motif6.motif0.00143264
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00546408
Pattern NameHomerSignificance
motif3.motif0.0267191
Unique TF-MoDISco TFs: #82
TF NameModiscoHomer
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00368969
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_111.7368499999999998e-05
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0570211
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0575856
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00809606
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00303227
metacluster_1/pattern_112.79975e-05
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0113485
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_88.216040000000001e-05
metacluster_1/pattern_90.0132664
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00032057900000000004
metacluster_1/pattern_90.0147732
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0426028
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00266291
metacluster_1/pattern_60.0277231
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0174873
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.014066200000000001
metacluster_1/pattern_90.0302808
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0402931
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0274089
metacluster_1/pattern_140.0584347
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_141.5087799999999998e-09
metacluster_1/pattern_150.017316400000000003
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000591916
Absent
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.8070400000000002e-06
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00100785
metacluster_1/pattern_90.023859599999999998
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00128815
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00548929
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.011947200000000002
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00874067
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000175938
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00102718
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00129449
metacluster_1/pattern_60.0106874
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_117.61672e-05
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_174.2770399999999995e-09
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0006178630000000001
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00018904099999999998
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_90.033969
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0224365
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_80.047769099999999995
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0163645
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0008950680000000001
metacluster_1/pattern_140.0372437
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_90.010312200000000002
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0330006
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.006857899999999999
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00226825
metacluster_1/pattern_150.00746146
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00852195
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0032341
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00368969
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0244475
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00669665
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000307572
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.016779
Absent
Ebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00968029
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.050438199999999996
metacluster_1/pattern_90.00433468
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0462094
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026734699999999997
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0205123
metacluster_1/pattern_110.052644500000000004
Absent
Prdm16
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0183117
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00722354
metacluster_1/pattern_115.773480000000001e-06
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.050438199999999996
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0101992
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00827274
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0232333
metacluster_1/pattern_110.037157199999999994
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0158607
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0263144
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0599947
metacluster_1/pattern_90.00376182
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00879301
Absent
Rxrg
Pattern NameModiscoSignificance
metacluster_1/pattern_90.041020999999999995
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0496577
metacluster_1/pattern_80.0110316
metacluster_1/pattern_90.0230801
metacluster_1/pattern_140.00169359
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0114259
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.018482
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0579114
metacluster_1/pattern_80.018947400000000003
metacluster_1/pattern_147.10015e-10
metacluster_1/pattern_150.009836399999999999
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.017734299999999998
metacluster_1/pattern_90.0147732
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.8070400000000002e-06
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_114.88925e-06
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00161281
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00432366
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.038108300000000005
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00355378
metacluster_1/pattern_150.00151811
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00463559
metacluster_1/pattern_64.08184e-05
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.006988600000000001
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_172.64104e-08
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00206099
metacluster_1/pattern_60.00335088
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0191863
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00554573
metacluster_1/pattern_150.00151811
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00036118900000000004
metacluster_1/pattern_150.017316400000000003
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00025983
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000336156
metacluster_1/pattern_90.0575856
metacluster_1/pattern_117.61672e-05
Absent
Unique Homer TFs: #6
TF NameModiscoHomer
Irf5Absent
Pattern NameHomerSignificance
motif3.motif0.0598497
Zic2Absent
Pattern NameHomerSignificance
motif1.motif0.054056799999999995
Snai1Absent
Pattern NameHomerSignificance
motif1.motif0.054056799999999995
Sall4Absent
Pattern NameHomerSignificance
motif14.motif0.0296094
Zbtb1Absent
Pattern NameHomerSignificance
motif2.motif0.0353518
Zic3Absent
Pattern NameHomerSignificance
motif1.motif0.054056799999999995