In [1]:
# Parameters
data_name = "CLP;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_94-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_94-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 19:01:14,150 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeCLP
    Cell GroupOther Immune Cells
    Experiment NameATAC
    Experiment GroupGEO
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep11389128969912.2998119702408519980.07139653140.080839860630.3335
    rep21389128969911.82141682005932494400.193424282970.144568566710.4081
    rep31389128969912.25711552209829274010.188822907150.147763298060.4083
    Modelling Metadata
    MetricValue
    auPRC0.5653
    Calibrated Recall at 50% FDR0.258
    Number of Positive Examples in Test Data101808
    Number of Negative Examples in Test Data7969043
    Imbalance Ratio in Test Data0.0126
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #23
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 7521 SequenceContrib ScoresHyp_Contrib Scores
Spi1, Spib, Etv2, Irf8, Irf4, Elf3, Ets1, Ehf, Erg, Spic,

Etv4, Etv6, Prdm1, Elf1, Gabpa, Elk1, Etv3, Elk4, Fli1, Irf3, Elf5,

XP_911724.4, Elf4, Elf2, Irf2, Irf1, Elk3, Etv1, Etv5, Ets2, Fev
metacluster_1/pattern_1 # seqlets: 6861 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 1994 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Egr1, Klf4,

Klf1, Klf8, Klf12, Zbtb17, Egr2, Sp5, E2f1, Zfp281, Klf5, Zfx, Wt1
metacluster_1/pattern_3 # seqlets: 1587 SequenceContrib ScoresHyp_Contrib Scores
Stat2, Stat1, Irf7, Zscan10, Irf9
metacluster_1/pattern_4 # seqlets: 1311 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Cbfb, Runx3
metacluster_1/pattern_5 # seqlets: 1025 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_6 # seqlets: 824 SequenceContrib ScoresHyp_Contrib Scores
Mbd2, E2f3, Spdef
metacluster_1/pattern_7 # seqlets: 768 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_8 # seqlets: 640 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_9 # seqlets: 614 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_10 # seqlets: 589 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_11 # seqlets: 581 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_12 # seqlets: 494 SequenceContrib ScoresHyp_Contrib Scores
Hes7, Hes1
metacluster_1/pattern_13 # seqlets: 468 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2a, Mef2c
metacluster_1/pattern_14 # seqlets: 354 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Usf2, Tfeb, Arntl, Tfec, Mitf, Tfe3, Bhlhe40, Srebf1, Clock,

Arnt, Mlx, Npas2, Creb3l2, Srebf2, Tcfl5, Atf1, Bhlhe41, Xbp1, Max, Mlxip,

Mycn
metacluster_1/pattern_15 # seqlets: 351 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf2, Atf7, Jdp2, Crem, Creb5, Atf3, Rfx1, Fosl2, Jun,

Hlf
metacluster_1/pattern_16 # seqlets: 336 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx6, Rfx7
metacluster_1/pattern_17 # seqlets: 226 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib, Nfic
metacluster_1/pattern_18 # seqlets: 132 SequenceContrib ScoresHyp_Contrib Scores
Bach2, Nfe2l2, Nfe2, Fosl1, Jund, Bach1, Fos, Fosb, Junb, Batf,

Mafk, Mafa, Mafg, Mafb, Maf, Maff
metacluster_1/pattern_19 # seqlets: 112 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42
metacluster_1/pattern_20 # seqlets: 74 SequenceContrib ScoresHyp_Contrib Scores
Rest
metacluster_1/pattern_21 # seqlets: 68 SequenceContrib ScoresHyp_Contrib Scores
Hoxc9, Hoxa9, Meis1, Cdx4, Evx1, Pdx1, Pbx2, Hoxb4, Hoxa2
metacluster_1/pattern_22 # seqlets: 32 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
Click here for Motifs by TF-MoDISco: #151
TF NamePattern(s)
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00210537
metacluster_1/pattern_30.00674503
metacluster_1/pattern_60.031061599999999998
metacluster_1/pattern_70.00279849
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_03.1219200000000003e-06
metacluster_1/pattern_39.585079999999999e-08
metacluster_1/pattern_70.00279849
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_09.083120000000001e-05
metacluster_1/pattern_60.00172444
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000153971
metacluster_1/pattern_33.1806e-14
metacluster_1/pattern_70.00432682
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000153971
metacluster_1/pattern_30.0462466
metacluster_1/pattern_70.00432682
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.030191200000000005
metacluster_1/pattern_60.0597097
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.00069926
metacluster_1/pattern_80.052712800000000004
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0196599
metacluster_1/pattern_60.028140699999999998
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.000607166
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00363121
metacluster_1/pattern_30.0471527
metacluster_1/pattern_70.00761956
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.016607499999999997
metacluster_1/pattern_60.00983797
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.0366049
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00224498
metacluster_1/pattern_30.00290886
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00287734
metacluster_1/pattern_60.000118076
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.023455700000000003
metacluster_1/pattern_60.00115359
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0055662
metacluster_1/pattern_60.000255003
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.00318249
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00801821
metacluster_1/pattern_60.00043131
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00964729
metacluster_1/pattern_60.000651417
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_30.000162575
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0182565
metacluster_1/pattern_30.0209277
metacluster_1/pattern_60.059355
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.00311712
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00579551
metacluster_1/pattern_60.011778700000000001
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.008904299999999999
metacluster_1/pattern_60.051546400000000006
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00681513
metacluster_1/pattern_30.014002700000000002
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.010656299999999999
metacluster_1/pattern_36.626649999999999e-07
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.016607499999999997
metacluster_1/pattern_60.000460819
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.016607499999999997
metacluster_1/pattern_60.000187602
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0187638
metacluster_1/pattern_60.0005840859999999999
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0216852
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.043581800000000004
metacluster_1/pattern_60.00035375300000000005
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_14.78476e-15
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_13.64522e-07
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00342884
metacluster_1/pattern_120.011722
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_28.33852e-06
metacluster_1/pattern_120.000946404
metacluster_1/pattern_150.00414558
metacluster_1/pattern_190.000354231
metacluster_1/pattern_220.0511851
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_22.55296e-05
metacluster_1/pattern_120.000946404
metacluster_1/pattern_150.038776099999999994
metacluster_1/pattern_190.004573399999999999
metacluster_1/pattern_220.0511851
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_23.80297e-05
metacluster_1/pattern_120.0007506460000000001
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00163899
metacluster_1/pattern_120.00478327
metacluster_1/pattern_150.0182293
metacluster_1/pattern_190.00309673
metacluster_1/pattern_220.0136607
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000525239
metacluster_1/pattern_120.00887543
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00107421
metacluster_1/pattern_120.004705300000000001
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00208715
metacluster_1/pattern_120.0007506460000000001
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00342884
metacluster_1/pattern_120.0380311
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0368269
metacluster_1/pattern_120.00790129
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0426599
metacluster_1/pattern_120.00495613
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00329066
metacluster_1/pattern_120.000946404
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.03723
metacluster_1/pattern_120.000946404
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00918967
metacluster_1/pattern_190.0268889
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0140451
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0176613
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.019296900000000002
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0396774
metacluster_1/pattern_120.0129123
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0426599
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0426599
metacluster_1/pattern_150.00649517
metacluster_1/pattern_190.00447051
metacluster_1/pattern_220.02159
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.056617999999999995
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00133906
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00160767
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00290886
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00805431
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_30.014002700000000002
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000942215
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.024542599999999998
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_48.04385e-05
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00229089
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_58.692330000000001e-14
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_55.423830000000001e-10
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_56.022539999999999e-09
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_54.95592e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_59.58048e-06
Mbd2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0242795
E2f3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.031061599999999998
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0327754
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_92.56808e-22
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_93.86448e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_91.1991199999999998e-13
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_113.1647100000000002e-06
Hes7
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0327543
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0352298
metacluster_1/pattern_140.0420793
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_136.27449e-10
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000290142
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_131.3721e-07
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00202327
metacluster_1/pattern_150.013491899999999998
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00299263
metacluster_1/pattern_152.92052e-05
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0010048
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00584444
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00171136
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00120417
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0019189
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0144929
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00512135
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0566539
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0557284
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0161785
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00120417
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0356116
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00516003
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00584444
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.014440600000000001
metacluster_1/pattern_150.0182293
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0202953
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0386678
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0475869
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_140.050416300000000004
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_140.057956799999999996
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00259004
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_150.001871
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_150.000680461
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0015718
metacluster_1/pattern_180.00137427
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_150.01763
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00197312
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0107326
metacluster_1/pattern_180.000101314
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0158729
metacluster_1/pattern_165.5917199999999995e-08
metacluster_1/pattern_190.018516499999999998
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_150.019715200000000002
metacluster_1/pattern_189.052e-05
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0519851
metacluster_1/pattern_182.0375e-05
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_150.054488699999999994
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00381459
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_168.625160000000002e-08
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000176408
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000588855
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00137149
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000131292
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000458206
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0120766
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.0375e-05
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.0375e-05
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.0375e-05
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_183.67476e-05
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0197725
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_183.67476e-05
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_183.67476e-05
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_180.000142239
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_180.000180302
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00894123
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00215382
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00426067
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00576895
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00644033
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00693319
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00734969
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_199.550110000000001e-06
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_191.14883e-05
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_190.0157371
Rest
Pattern NameModiscoSignificance
metacluster_1/pattern_201.80535e-15
Hoxc9
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00227133
Hoxa9
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00227133
Meis1
Pattern NameModiscoSignificance
metacluster_1/pattern_210.0009801039999999999
Cdx4
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00232817
Evx1
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00232817
Pdx1
Pattern NameModiscoSignificance
metacluster_1/pattern_210.0161588
Pbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_210.024125999999999998
Hoxb4
Pattern NameModiscoSignificance
metacluster_1/pattern_210.056897
Hoxa2
Pattern NameModiscoSignificance
metacluster_1/pattern_210.056897
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_223.29335e-05
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #64
TF NameModiscoHomer
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00329066
metacluster_1/pattern_120.000946404
Pattern NameHomerSignificance
motif4.motif0.00141083
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000153971
metacluster_1/pattern_33.1806e-14
metacluster_1/pattern_70.00432682
Pattern NameHomerSignificance
motif2.motif2.15879e-05
motif6.motif0.00405752
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.00318249
Pattern NameHomerSignificance
motif2.motif0.015540700000000001
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00801821
metacluster_1/pattern_60.00043131
Pattern NameHomerSignificance
motif2.motif0.025799700000000002
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_93.86448e-21
Pattern NameHomerSignificance
motif5.motif2.7428699999999997e-07
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0368269
metacluster_1/pattern_120.00790129
Pattern NameHomerSignificance
motif4.motif0.000544771
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_09.083120000000001e-05
metacluster_1/pattern_60.00172444
Pattern NameHomerSignificance
motif2.motif0.00276432
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.016607499999999997
metacluster_1/pattern_60.00983797
Pattern NameHomerSignificance
motif2.motif0.035094099999999996
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_22.55296e-05
metacluster_1/pattern_120.000946404
metacluster_1/pattern_150.038776099999999994
metacluster_1/pattern_190.004573399999999999
metacluster_1/pattern_220.0511851
Pattern NameHomerSignificance
motif4.motif6.564019999999999e-06
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000153971
metacluster_1/pattern_30.0462466
metacluster_1/pattern_70.00432682
Pattern NameHomerSignificance
motif2.motif2.2925500000000003e-05
motif6.motif0.00492197
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_23.80297e-05
metacluster_1/pattern_120.0007506460000000001
Pattern NameHomerSignificance
motif4.motif2.1791300000000003e-05
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0182565
metacluster_1/pattern_30.0209277
metacluster_1/pattern_60.059355
Pattern NameHomerSignificance
motif2.motif0.0367191
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_03.1219200000000003e-06
metacluster_1/pattern_39.585079999999999e-08
metacluster_1/pattern_70.00279849
Pattern NameHomerSignificance
motif2.motif2.0214599999999998e-08
motif6.motif0.00405752
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00210537
metacluster_1/pattern_30.00674503
metacluster_1/pattern_60.031061599999999998
metacluster_1/pattern_70.00279849
Pattern NameHomerSignificance
motif2.motif0.0009004789999999999
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.010656299999999999
metacluster_1/pattern_36.626649999999999e-07
Pattern NameHomerSignificance
motif2.motif0.015489500000000002
motif6.motif0.0336609
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.00311712
Pattern NameHomerSignificance
motif2.motif0.017678
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00229089
Pattern NameHomerSignificance
motif3.motif0.00516567
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.016607499999999997
metacluster_1/pattern_60.000187602
Pattern NameHomerSignificance
motif2.motif0.0367191
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_54.95592e-06
Pattern NameHomerSignificance
motif7.motif2.0649699999999996e-05
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.019296900000000002
Pattern NameHomerSignificance
motif4.motif0.0182283
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_30.000162575
Pattern NameHomerSignificance
motif2.motif0.00675037
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000525239
metacluster_1/pattern_120.00887543
Pattern NameHomerSignificance
motif4.motif0.000948877
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00107421
metacluster_1/pattern_120.004705300000000001
Pattern NameHomerSignificance
motif4.motif0.000253192
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_191.14883e-05
Pattern NameHomerSignificance
motif16.motif0.0185429
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.0366049
Pattern NameHomerSignificance
motif2.motif0.015540700000000001
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.03723
metacluster_1/pattern_120.000946404
Pattern NameHomerSignificance
motif4.motif0.0157554
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0426599
Pattern NameHomerSignificance
motif4.motif0.0182283
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00918967
metacluster_1/pattern_190.0268889
Pattern NameHomerSignificance
motif4.motif0.0160786
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_91.1991199999999998e-13
Pattern NameHomerSignificance
motif5.motif1.4480799999999999e-05
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00208715
metacluster_1/pattern_120.0007506460000000001
Pattern NameHomerSignificance
motif4.motif0.000652505
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_59.58048e-06
Pattern NameHomerSignificance
motif7.motif0.000129639
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.000607166
Pattern NameHomerSignificance
motif2.motif0.015489500000000002
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.030191200000000005
metacluster_1/pattern_60.0597097
Pattern NameHomerSignificance
motif2.motif0.0523681
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0055662
metacluster_1/pattern_60.000255003
Pattern NameHomerSignificance
motif2.motif0.0211978
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0187638
metacluster_1/pattern_60.0005840859999999999
Pattern NameHomerSignificance
motif2.motif0.0386337
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00363121
metacluster_1/pattern_30.0471527
metacluster_1/pattern_70.00761956
Pattern NameHomerSignificance
motif2.motif0.00309803
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000942215
Pattern NameHomerSignificance
motif3.motif0.0322753
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00681513
metacluster_1/pattern_30.014002700000000002
Pattern NameHomerSignificance
motif2.motif0.010933400000000001
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00224498
metacluster_1/pattern_30.00290886
Pattern NameHomerSignificance
motif2.motif0.00675037
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0426599
metacluster_1/pattern_150.00649517
metacluster_1/pattern_190.00447051
metacluster_1/pattern_220.02159
Pattern NameHomerSignificance
motif4.motif0.043313
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_92.56808e-22
Pattern NameHomerSignificance
motif5.motif1.29954e-07
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.043581800000000004
metacluster_1/pattern_60.00035375300000000005
Pattern NameHomerSignificance
motif2.motif0.0571434
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0196599
metacluster_1/pattern_60.028140699999999998
Pattern NameHomerSignificance
motif2.motif0.0362684
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_14.78476e-15
Pattern NameHomerSignificance
motif1.motif7.79979e-05
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00287734
metacluster_1/pattern_60.000118076
Pattern NameHomerSignificance
motif2.motif0.010933400000000001
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.023455700000000003
metacluster_1/pattern_60.00115359
Pattern NameHomerSignificance
motif2.motif0.0482897
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_13.64522e-07
Pattern NameHomerSignificance
motif1.motif0.000718641
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_55.423830000000001e-10
Pattern NameHomerSignificance
motif7.motif5.60606e-06
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0426599
metacluster_1/pattern_120.00495613
Pattern NameHomerSignificance
motif4.motif0.051342
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00398068
metacluster_1/pattern_60.00069926
metacluster_1/pattern_80.052712800000000004
Pattern NameHomerSignificance
motif2.motif0.0141535
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_28.33852e-06
metacluster_1/pattern_120.000946404
metacluster_1/pattern_150.00414558
metacluster_1/pattern_190.000354231
metacluster_1/pattern_220.0511851
Pattern NameHomerSignificance
motif4.motif2.38692e-06
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.024542599999999998
Pattern NameHomerSignificance
motif3.motif0.00431526
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_223.29335e-05
Pattern NameHomerSignificance
motif14.motif0.000475715
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00342884
metacluster_1/pattern_120.0380311
Pattern NameHomerSignificance
motif4.motif0.031451099999999996
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_56.022539999999999e-09
Pattern NameHomerSignificance
motif7.motif2.9762799999999996e-06
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.016607499999999997
metacluster_1/pattern_60.000460819
Pattern NameHomerSignificance
motif2.motif0.029322900000000006
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00342884
metacluster_1/pattern_120.011722
Pattern NameHomerSignificance
motif4.motif0.029133
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00964729
metacluster_1/pattern_60.000651417
Pattern NameHomerSignificance
motif2.motif0.043434600000000004
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00163899
metacluster_1/pattern_120.00478327
metacluster_1/pattern_150.0182293
metacluster_1/pattern_190.00309673
metacluster_1/pattern_220.0136607
Pattern NameHomerSignificance
motif4.motif0.00857576
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.008904299999999999
metacluster_1/pattern_60.051546400000000006
Pattern NameHomerSignificance
motif2.motif0.0211978
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_48.04385e-05
Pattern NameHomerSignificance
motif3.motif0.00431526
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_113.1647100000000002e-06
Pattern NameHomerSignificance
motif9.motif1.85519e-06
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_58.692330000000001e-14
Pattern NameHomerSignificance
motif7.motif4.3931100000000004e-08
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00579551
metacluster_1/pattern_60.011778700000000001
Pattern NameHomerSignificance
motif2.motif0.0156251
Unique TF-MoDISco TFs: #87
TF NameModiscoHomer
Cdx4
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00232817
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_150.019715200000000002
metacluster_1/pattern_189.052e-05
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0010048
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0396774
metacluster_1/pattern_120.0129123
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0176613
Absent
Hes7
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0327543
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00584444
Absent
Hes1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0352298
metacluster_1/pattern_140.0420793
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_150.001871
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0216852
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_180.000180302
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_183.67476e-05
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.0375e-05
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000176408
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0158729
metacluster_1/pattern_165.5917199999999995e-08
metacluster_1/pattern_190.018516499999999998
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00202327
metacluster_1/pattern_150.013491899999999998
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0475869
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000458206
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_168.625160000000002e-08
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0019189
Absent
Pdx1
Pattern NameModiscoSignificance
metacluster_1/pattern_210.0161588
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_199.550110000000001e-06
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0120766
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00516003
Absent
E2f3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.031061599999999998
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00576895
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0161785
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_150.054488699999999994
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_150.01763
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.056617999999999995
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00512135
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000588855
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0566539
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_190.0157371
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00381459
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.014440600000000001
metacluster_1/pattern_150.0182293
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_150.000680461
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0140451
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000131292
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0202953
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00171136
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0356116
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_180.000142239
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00197312
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00133906
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0015718
metacluster_1/pattern_180.00137427
Absent
Hoxc9
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00227133
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00259004
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00584444
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00160767
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0557284
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00894123
Absent
Hoxb4
Pattern NameModiscoSignificance
metacluster_1/pattern_210.056897
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0107326
metacluster_1/pattern_180.000101314
Absent
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0327754
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000290142
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0386678
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_136.27449e-10
Absent
Hoxa2
Pattern NameModiscoSignificance
metacluster_1/pattern_210.056897
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0519851
metacluster_1/pattern_182.0375e-05
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.0375e-05
Absent
Evx1
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00232817
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00137149
Absent
Pbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_210.024125999999999998
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00299263
metacluster_1/pattern_152.92052e-05
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0197725
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_140.050416300000000004
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_131.3721e-07
Absent
Mbd2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0242795
Absent
Rest
Pattern NameModiscoSignificance
metacluster_1/pattern_201.80535e-15
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_30.014002700000000002
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00215382
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00644033
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00693319
Absent
Hoxa9
Pattern NameModiscoSignificance
metacluster_1/pattern_210.00227133
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0144929
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00426067
Absent
Meis1
Pattern NameModiscoSignificance
metacluster_1/pattern_210.0009801039999999999
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00290886
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00805431
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_183.67476e-05
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00734969
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00120417
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_140.057956799999999996
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00120417
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_182.0375e-05
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_183.67476e-05
Absent
Unique Homer TFs: #4
TF NameModiscoHomer
Klf15Absent
Pattern NameHomerSignificance
motif4.motif0.0316187
Zbtb1Absent
Pattern NameHomerSignificance
motif4.motif0.043313
E2f7Absent
Pattern NameHomerSignificance
motif4.motif0.0182283
E2f6Absent
Pattern NameHomerSignificance
motif4.motif0.043313