In [1]:
# Parameters
data_name = "matureB;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_8-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_8-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:41:46,060 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typemature B cells
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1976147662710.53855073228081815830.161361345910.121160993880.3175
    Modelling Metadata
    MetricValue
    auPRC0.5881
    Calibrated Recall at 50% FDR0.232
    Number of Positive Examples in Test Data83836
    Number of Negative Examples in Test Data7987015
    Imbalance Ratio in Test Data0.0104
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #24
Pattern NameTF Name(s)Modisco
metacluster_0/pattern_0 # seqlets: 6925 SequenceContrib ScoresHyp_Contrib Scores
Spib, Spi1, Irf8, Irf4, Etv2, Ets1, Spic, Etv6, Erg, Etv4,

Etv3, Fli1, Gabpa, Elk1, XP_911724.4, Ehf, Elf1, Elf3, Elf4, Elk4, Elk3,

Elf2, Etv1, Etv5, Elf5, Prdm1, Irf3, Irf2, Fev, Irf1, Spdef
metacluster_0/pattern_1 # seqlets: 4961 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_0/pattern_2 # seqlets: 3479 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Klf3, Sp3, Sp1, E2f4, Klf7, Klf4, Klf6, Klf12,

Klf8, Klf1, Egr1, Egr2, Zbtb17, E2f1, Klf5, Zfp281, Sp5, Zfp740, Egr3,

Zfx, Zbtb1, Sall4
metacluster_0/pattern_3 # seqlets: 2237 SequenceContrib ScoresHyp_Contrib Scores
Irf7, Stat2, Stat1, Zscan10, Irf9
metacluster_0/pattern_4 # seqlets: 1682 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_0/pattern_5 # seqlets: 1123 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Pbx3, Foxi1
metacluster_0/pattern_6 # seqlets: 763 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_0/pattern_7 # seqlets: 661 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfec, Usf2, Arntl, Mitf, Tfeb, Bhlhe40, Srebf1, Tfe3, Clock,

Mlx, Arnt, Npas2, Srebf2, Tcfl5, Creb3l2, Atf1, Bhlhe41, Xbp1, Hlf, Dbp,

Arnt2
metacluster_0/pattern_8 # seqlets: 642 SequenceContrib ScoresHyp_Contrib Scores
Atf7, Atf2, Creb1, Creb5, Jdp2, Crem, Rxrb, Mafb, Nfil3, Jun
metacluster_0/pattern_9 # seqlets: 554 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42, Rfx1
metacluster_0/pattern_10 # seqlets: 511 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_0/pattern_11 # seqlets: 389 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Cbfb, Runx3
metacluster_0/pattern_12 # seqlets: 381 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_13 # seqlets: 323 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx6, Rfx7
metacluster_0/pattern_14 # seqlets: 318 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_0/pattern_15 # seqlets: 262 SequenceContrib ScoresHyp_Contrib Scores
Fosl2, Fosl1, Gmeb2, Atf3, Cebpb, Gmeb1, Tef
metacluster_0/pattern_16 # seqlets: 206 SequenceContrib ScoresHyp_Contrib Scores
Mbd2
metacluster_0/pattern_17 # seqlets: 201 SequenceContrib ScoresHyp_Contrib Scores
Ets2
metacluster_0/pattern_18 # seqlets: 178 SequenceContrib ScoresHyp_Contrib Scores
Stat4
metacluster_0/pattern_19 # seqlets: 149 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_0/pattern_20 # seqlets: 147 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2a, Mef2c
metacluster_0/pattern_21 # seqlets: 119 SequenceContrib ScoresHyp_Contrib Scores
Fos, Jund, Batf, Fosb, Junb, Bach2, Bach1, Mafa, Nfe2l2, Nfe2,

Mafk, Mafg, Maff
metacluster_0/pattern_22 # seqlets: 70 SequenceContrib ScoresHyp_Contrib Scores
Nfib, Nfia, Nfic
metacluster_0/pattern_23 # seqlets: 35 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #152
TF NamePattern(s)
Spib
Pattern NameModiscoSignificance
metacluster_0/pattern_09.29973e-06
metacluster_0/pattern_36.68465e-07
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000447468
metacluster_0/pattern_30.00502309
metacluster_0/pattern_170.0221986
Irf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000124081
metacluster_0/pattern_36.187010000000001e-13
Irf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000125742
metacluster_0/pattern_30.0233422
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000160774
metacluster_0/pattern_170.00683244
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000521027
metacluster_0/pattern_120.0236759
metacluster_0/pattern_160.010769299999999999
metacluster_0/pattern_170.00296708
Spic
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0004939909999999999
metacluster_0/pattern_30.030735200000000004
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00197064
metacluster_0/pattern_160.0572419
metacluster_0/pattern_170.0449196
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005829
metacluster_0/pattern_160.00889932
metacluster_0/pattern_170.0221986
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00184471
metacluster_0/pattern_160.0200627
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005829
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0032741999999999997
metacluster_0/pattern_160.00514857
metacluster_0/pattern_170.015050899999999999
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_00.014679300000000001
metacluster_0/pattern_160.0572816
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00163713
metacluster_0/pattern_120.0260072
metacluster_0/pattern_160.00260059
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005829
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00330157
metacluster_0/pattern_170.0324085
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0006839680000000001
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00867678
metacluster_0/pattern_170.016038399999999998
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0008596560000000001
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0013090999999999999
metacluster_0/pattern_160.010769299999999999
metacluster_0/pattern_170.0449196
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00184471
metacluster_0/pattern_160.021920699999999998
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.017221
metacluster_0/pattern_160.0367766
metacluster_0/pattern_170.0221986
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00197064
metacluster_0/pattern_160.024347099999999997
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00197064
metacluster_0/pattern_160.00889932
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.014636700000000002
metacluster_0/pattern_170.015050899999999999
Prdm1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00508827
metacluster_0/pattern_30.00348489
Irf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00637653
metacluster_0/pattern_30.00116355
Irf2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00702415
metacluster_0/pattern_30.00993192
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0083053
metacluster_0/pattern_160.00800973
Irf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0111124
metacluster_0/pattern_32.9544400000000003e-06
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_00.015364500000000001
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_13.9349e-14
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_13.25977e-08
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000955801
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_22.7226599999999995e-06
metacluster_0/pattern_90.000118987
metacluster_0/pattern_160.000247795
metacluster_0/pattern_190.0424348
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_28.16799e-06
metacluster_0/pattern_160.024347099999999997
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_21.00958e-05
metacluster_0/pattern_90.00181554
metacluster_0/pattern_160.00162093
metacluster_0/pattern_190.030674700000000003
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00029477700000000003
metacluster_0/pattern_90.0014455
metacluster_0/pattern_160.00260059
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00029477700000000003
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000325771
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00587054
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000367837
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00817465
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000450882
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.023933799999999998
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.027038099999999995
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0211827
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00740265
metacluster_0/pattern_90.0246827
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.010630200000000001
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_20.011204
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0224922
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0224922
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_20.027038099999999995
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0311499
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0341264
metacluster_0/pattern_90.00220138
metacluster_0/pattern_150.0351389
metacluster_0/pattern_160.00436031
metacluster_0/pattern_190.014237999999999999
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0368643
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.04999
Irf7
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00274194
Stat2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00348489
Stat1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00348489
Zscan10
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0079541
Irf9
Pattern NameModiscoSignificance
metacluster_0/pattern_30.012198700000000002
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_47.46074e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_53.51919e-12
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_52.39873e-10
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_57.1371499999999995e-09
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_55.24415e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_55.24415e-06
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_67.4478e-22
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_61.1054899999999999e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_61.17248e-13
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00359334
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
metacluster_0/pattern_80.038542900000000005
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00410191
metacluster_0/pattern_150.00254021
metacluster_0/pattern_160.00889932
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00603957
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00255331
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00136409
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00594623
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00263084
metacluster_0/pattern_80.059687300000000006
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0353573
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0312505
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_70.035011900000000006
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_70.006567699999999999
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.018815900000000003
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00963982
metacluster_0/pattern_80.030019599999999997
metacluster_0/pattern_150.049443
metacluster_0/pattern_160.014237399999999999
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0102451
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.045194099999999994
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.045194099999999994
metacluster_0/pattern_150.049443
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0469801
metacluster_0/pattern_80.0501351
Arnt2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0481427
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00112154
metacluster_0/pattern_150.032206599999999995
metacluster_0/pattern_160.03159120000000001
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00126622
metacluster_0/pattern_150.030481400000000002
metacluster_0/pattern_160.0572419
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00264472
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_160.024347099999999997
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_80.000469858
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00747266
metacluster_0/pattern_150.0407713
metacluster_0/pattern_160.03159120000000001
metacluster_0/pattern_210.000680356
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00729863
metacluster_0/pattern_150.0464723
metacluster_0/pattern_160.0408507
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.026449
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.027927800000000003
metacluster_0/pattern_210.0291459
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_80.038542900000000005
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_80.047205800000000006
metacluster_0/pattern_150.0452155
metacluster_0/pattern_160.051232799999999995
metacluster_0/pattern_212.7926e-05
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_93.87537e-06
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_99.29523e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_90.012911099999999998
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0160879
metacluster_0/pattern_137.80417e-10
metacluster_0/pattern_150.0452715
metacluster_0/pattern_160.059659199999999996
metacluster_0/pattern_180.0358754
Nfkb2
Pattern NameModiscoSignificance
metacluster_0/pattern_101.73304e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000321497
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00147969
metacluster_0/pattern_170.0373165
Relb
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00116898
Rel
Pattern NameModiscoSignificance
metacluster_0/pattern_100.051944000000000004
Runx1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0036626999999999996
Runx2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00121772
Cbfb
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00282441
Runx3
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00282441
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00486795
metacluster_0/pattern_180.030340199999999998
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_136.62517e-09
metacluster_0/pattern_180.057387099999999996
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000359712
metacluster_0/pattern_180.021447499999999998
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00151987
metacluster_0/pattern_180.000995824
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00291264
metacluster_0/pattern_180.0144637
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00786214
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_211.81717e-05
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_210.0122421
Gmeb2
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_210.000350394
Cebpb
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0484898
Gmeb1
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0484898
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_150.053736900000000004
Mbd2
Pattern NameModiscoSignificance
metacluster_0/pattern_160.042367
Ets2
Pattern NameModiscoSignificance
metacluster_0/pattern_170.0429038
Stat4
Pattern NameModiscoSignificance
metacluster_0/pattern_180.0437953
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_191.8074800000000002e-05
Mef2d
Pattern NameModiscoSignificance
metacluster_0/pattern_201.05805e-08
Mef2a
Pattern NameModiscoSignificance
metacluster_0/pattern_200.00031820599999999997
Mef2c
Pattern NameModiscoSignificance
metacluster_0/pattern_201.0821199999999999e-07
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_218.09898e-06
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0153828
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0236192
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_210.000314678
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_210.038567500000000005
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_210.00308731
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_210.00864847
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_210.00983476
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0122421
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_210.011208599999999999
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0151061
Mafg
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0318
Maff
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0442885
Nfib
Pattern NameModiscoSignificance
metacluster_0/pattern_220.00072447
Nfia
Pattern NameModiscoSignificance
metacluster_0/pattern_220.00335649
Nfic
Pattern NameModiscoSignificance
metacluster_0/pattern_220.0155066
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #67
TF NameModiscoHomer
Spic
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0004939909999999999
metacluster_0/pattern_30.030735200000000004
Pattern NameHomerSignificance
motif2.motif0.00043013
Irf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000125742
metacluster_0/pattern_30.0233422
Pattern NameHomerSignificance
motif2.motif0.000277313
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00029477700000000003
Pattern NameHomerSignificance
motif3.motif0.000588669
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000955801
Pattern NameHomerSignificance
motif3.motif0.00586277
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00197064
metacluster_0/pattern_160.00889932
Pattern NameHomerSignificance
motif2.motif0.000663865
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00587054
Pattern NameHomerSignificance
motif3.motif0.0295215
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_00.015364500000000001
Pattern NameHomerSignificance
motif2.motif0.0110522
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000447468
metacluster_0/pattern_30.00502309
metacluster_0/pattern_170.0221986
Pattern NameHomerSignificance
motif2.motif0.00044969199999999996
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.014636700000000002
metacluster_0/pattern_170.015050899999999999
Pattern NameHomerSignificance
motif2.motif0.035863400000000004
Prdm1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00508827
metacluster_0/pattern_30.00348489
Pattern NameHomerSignificance
motif2.motif0.00520936
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00029477700000000003
metacluster_0/pattern_90.0014455
metacluster_0/pattern_160.00260059
Pattern NameHomerSignificance
motif3.motif0.00261776
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0013090999999999999
metacluster_0/pattern_160.010769299999999999
metacluster_0/pattern_170.0449196
Pattern NameHomerSignificance
motif2.motif0.000493315
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00740265
metacluster_0/pattern_90.0246827
Pattern NameHomerSignificance
motif3.motif0.0054779
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00817465
Pattern NameHomerSignificance
motif3.motif0.016067500000000002
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.027038099999999995
Pattern NameHomerSignificance
motif3.motif0.0435664
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00197064
metacluster_0/pattern_160.0572419
metacluster_0/pattern_170.0449196
Pattern NameHomerSignificance
motif2.motif0.00789777
Irf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000124081
metacluster_0/pattern_36.187010000000001e-13
Pattern NameHomerSignificance
motif2.motif0.000278833
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000450882
Pattern NameHomerSignificance
motif3.motif0.00050527
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0224922
Pattern NameHomerSignificance
motif3.motif0.0437914
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_00.014679300000000001
metacluster_0/pattern_160.0572816
Pattern NameHomerSignificance
motif2.motif0.00444919
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_22.7226599999999995e-06
metacluster_0/pattern_90.000118987
metacluster_0/pattern_160.000247795
metacluster_0/pattern_190.0424348
Pattern NameHomerSignificance
motif3.motif0.00019880900000000001
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00264472
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_160.024347099999999997
Pattern NameHomerSignificance
motif7.motif0.0414719
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_90.012911099999999998
Pattern NameHomerSignificance
motif12.motif0.041113699999999996
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_53.51919e-12
Pattern NameHomerSignificance
motif9.motif0.00555875
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00184471
metacluster_0/pattern_160.0200627
Pattern NameHomerSignificance
motif2.motif0.00183315
Irf9
Pattern NameModiscoSignificance
metacluster_0/pattern_30.012198700000000002
Pattern NameHomerSignificance
motif2.motif0.03773169999999999
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0006839680000000001
Pattern NameHomerSignificance
motif2.motif0.00027499400000000003
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_61.1054899999999999e-21
Pattern NameHomerSignificance
motif4.motif5.71611e-08
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005829
metacluster_0/pattern_160.00889932
metacluster_0/pattern_170.0221986
Pattern NameHomerSignificance
motif2.motif0.000335103
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0008596560000000001
Pattern NameHomerSignificance
motif2.motif0.000470197
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00330157
metacluster_0/pattern_170.0324085
Pattern NameHomerSignificance
motif2.motif0.00179358
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00184471
metacluster_0/pattern_160.021920699999999998
Pattern NameHomerSignificance
motif2.motif0.000626671
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0032741999999999997
metacluster_0/pattern_160.00514857
metacluster_0/pattern_170.015050899999999999
Pattern NameHomerSignificance
motif2.motif0.00108116
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_20.011204
Pattern NameHomerSignificance
motif3.motif0.00795341
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0224922
Pattern NameHomerSignificance
motif3.motif0.0267613
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_28.16799e-06
metacluster_0/pattern_160.024347099999999997
Pattern NameHomerSignificance
motif3.motif0.00019880900000000001
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000325771
Pattern NameHomerSignificance
motif3.motif0.00029920099999999997
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000521027
metacluster_0/pattern_120.0236759
metacluster_0/pattern_160.010769299999999999
metacluster_0/pattern_170.00296708
Pattern NameHomerSignificance
motif2.motif0.000301118
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0083053
metacluster_0/pattern_160.00800973
Pattern NameHomerSignificance
motif2.motif0.0057961
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_67.4478e-22
Pattern NameHomerSignificance
motif4.motif3.23109e-08
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_57.1371499999999995e-09
Pattern NameHomerSignificance
motif9.motif0.00563201
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00163713
metacluster_0/pattern_120.0260072
metacluster_0/pattern_160.00260059
Pattern NameHomerSignificance
motif2.motif0.00043013
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.017221
metacluster_0/pattern_160.0367766
metacluster_0/pattern_170.0221986
Pattern NameHomerSignificance
motif2.motif0.000663865
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_99.29523e-06
Pattern NameHomerSignificance
motif12.motif0.00623998
Irf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00637653
metacluster_0/pattern_30.00116355
Pattern NameHomerSignificance
motif2.motif0.0111139
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_52.39873e-10
Pattern NameHomerSignificance
motif9.motif0.00648131
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0211827
Pattern NameHomerSignificance
motif3.motif0.0526793
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_47.46074e-07
Pattern NameHomerSignificance
motif10.motif2.6803800000000002e-05
Irf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0111124
metacluster_0/pattern_32.9544400000000003e-06
Pattern NameHomerSignificance
motif2.motif0.00940342
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_21.00958e-05
metacluster_0/pattern_90.00181554
metacluster_0/pattern_160.00162093
metacluster_0/pattern_190.030674700000000003
Pattern NameHomerSignificance
motif3.motif0.00019880900000000001
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00867678
metacluster_0/pattern_170.016038399999999998
Pattern NameHomerSignificance
motif2.motif0.00687705
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005829
Pattern NameHomerSignificance
motif2.motif0.00039672199999999996
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.023933799999999998
Pattern NameHomerSignificance
motif3.motif0.039089
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_55.24415e-06
Pattern NameHomerSignificance
motif9.motif0.0385199
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0368643
Pattern NameHomerSignificance
motif3.motif0.013322799999999997
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_55.24415e-06
Pattern NameHomerSignificance
motif9.motif0.0594175
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_93.87537e-06
Pattern NameHomerSignificance
motif12.motif0.000515321
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00197064
metacluster_0/pattern_160.024347099999999997
Pattern NameHomerSignificance
motif2.motif0.0006945860000000001
Spib
Pattern NameModiscoSignificance
metacluster_0/pattern_09.29973e-06
metacluster_0/pattern_36.68465e-07
Pattern NameHomerSignificance
motif2.motif0.00010724
Irf2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00702415
metacluster_0/pattern_30.00993192
Pattern NameHomerSignificance
motif2.motif0.00520936
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_13.25977e-08
Pattern NameHomerSignificance
motif1.motif0.000821805
motif8.motif0.00472827
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000160774
metacluster_0/pattern_170.00683244
Pattern NameHomerSignificance
motif2.motif0.00043013
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_20.000367837
Pattern NameHomerSignificance
motif3.motif0.00125043
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005829
Pattern NameHomerSignificance
motif2.motif0.00043013
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_13.9349e-14
Pattern NameHomerSignificance
motif1.motif0.000418476
motif8.motif0.0038510999999999997
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.010630200000000001
Pattern NameHomerSignificance
motif3.motif0.00418418
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_61.17248e-13
Pattern NameHomerSignificance
motif4.motif1.10967e-05
Unique TF-MoDISco TFs: #85
TF NameModiscoHomer
Fos
Pattern NameModiscoSignificance
metacluster_0/pattern_218.09898e-06
Absent
Jund
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0153828
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00603957
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.045194099999999994
metacluster_0/pattern_150.049443
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0311499
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_70.006567699999999999
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
Absent
Rel
Pattern NameModiscoSignificance
metacluster_0/pattern_100.051944000000000004
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00963982
metacluster_0/pattern_80.030019599999999997
metacluster_0/pattern_150.049443
metacluster_0/pattern_160.014237399999999999
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00282441
Absent
Maff
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0442885
Absent
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_80.047205800000000006
metacluster_0/pattern_150.0452155
metacluster_0/pattern_160.051232799999999995
metacluster_0/pattern_212.7926e-05
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00274194
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_136.62517e-09
metacluster_0/pattern_180.057387099999999996
Absent
Nfkb2
Pattern NameModiscoSignificance
metacluster_0/pattern_101.73304e-05
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.018815900000000003
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.026449
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_0/pattern_210.00983476
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_0/pattern_220.00335649
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_0/pattern_140.00786214
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00348489
Absent
Mbd2
Pattern NameModiscoSignificance
metacluster_0/pattern_160.042367
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_210.000350394
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00359334
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0122421
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_0/pattern_210.011208599999999999
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_0/pattern_110.0036626999999999996
Absent
Tef
Pattern NameModiscoSignificance
metacluster_0/pattern_150.053736900000000004
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
metacluster_0/pattern_80.038542900000000005
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_20.027038099999999995
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.04999
Absent
Stat4
Pattern NameModiscoSignificance
metacluster_0/pattern_180.0437953
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_210.0122421
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_130.000359712
metacluster_0/pattern_180.021447499999999998
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0102451
Absent
Junb
Pattern NameModiscoSignificance
metacluster_0/pattern_210.038567500000000005
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0079541
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00136409
Absent
Batf
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0236192
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00255331
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0151061
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_0/pattern_210.00864847
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00126622
metacluster_0/pattern_150.030481400000000002
metacluster_0/pattern_160.0572419
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00747266
metacluster_0/pattern_150.0407713
metacluster_0/pattern_160.03159120000000001
metacluster_0/pattern_210.000680356
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00151987
metacluster_0/pattern_180.000995824
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00282441
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0160879
metacluster_0/pattern_137.80417e-10
metacluster_0/pattern_150.0452715
metacluster_0/pattern_160.059659199999999996
metacluster_0/pattern_180.0358754
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00486795
metacluster_0/pattern_180.030340199999999998
Absent
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00147969
metacluster_0/pattern_170.0373165
Absent
Gmeb1
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0484898
Absent
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0353573
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
metacluster_0/pattern_211.81717e-05
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_0/pattern_200.00031820599999999997
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_0/pattern_210.00308731
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_0/pattern_170.0429038
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_191.8074800000000002e-05
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00594623
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.00348489
Absent
Cebpb
Pattern NameModiscoSignificance
metacluster_0/pattern_150.0484898
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00263084
metacluster_0/pattern_80.059687300000000006
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00410191
metacluster_0/pattern_150.00254021
metacluster_0/pattern_160.00889932
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.045194099999999994
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0031548
Absent
Arnt2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0481427
Absent
Nfkb1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000321497
Absent
Relb
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00116898
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_0/pattern_80.027927800000000003
metacluster_0/pattern_210.0291459
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0312505
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_0/pattern_201.0821199999999999e-07
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0469801
metacluster_0/pattern_80.0501351
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_0/pattern_80.038542900000000005
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00291264
metacluster_0/pattern_180.0144637
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00112154
metacluster_0/pattern_150.032206599999999995
metacluster_0/pattern_160.03159120000000001
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_0/pattern_220.0155066
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0341264
metacluster_0/pattern_90.00220138
metacluster_0/pattern_150.0351389
metacluster_0/pattern_160.00436031
metacluster_0/pattern_190.014237999999999999
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_0/pattern_210.0318
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_0/pattern_201.05805e-08
Absent
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00729863
metacluster_0/pattern_150.0464723
metacluster_0/pattern_160.0408507
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_80.000469858
Absent
Gmeb2
Pattern NameModiscoSignificance
metacluster_0/pattern_150.027485700000000002
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_0/pattern_220.00072447
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_0/pattern_210.000314678
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_70.035011900000000006
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_0/pattern_110.00121772
Absent
Unique Homer TFs: #3
TF NameModiscoHomer
E2f6Absent
Pattern NameHomerSignificance
motif3.motif0.039089
Klf15Absent
Pattern NameHomerSignificance
motif3.motif0.011498999999999999
E2f7Absent
Pattern NameHomerSignificance
motif3.motif0.013322799999999997