In [1]:
# Parameters
data_name = "Th2_nippo;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_87-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_87-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:59:43,503 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeTh2 (Nippo infected)
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep112757810150610.223158219367139431860.239690042190.1547200744950.3449
    Modelling Metadata
    MetricValue
    auPRC0.5825
    Calibrated Recall at 50% FDR0.211
    Number of Positive Examples in Test Data112098
    Number of Negative Examples in Test Data7958753
    Imbalance Ratio in Test Data0.0139
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #19
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 4736 SequenceContrib ScoresHyp_Contrib Scores
Ets1, Erg, Fli1, Elk1, Gabpa, Elk4, Etv2, Etv5, Etv4, Elf1,

Elf2, Elk3, Spi1, Fev, Etv6, Ehf, Etv1, Etv3, XP_911724.4, Spib, Elf3,

Elf4, Elf5, Spdef, Irf8, Irf4, Spic, Ets2, Stat4
metacluster_1/pattern_1 # seqlets: 3561 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp4, Sp3, Sp1, Klf3, E2f4, Klf7, Klf6, Klf4, Klf8,

Klf12, Klf1, Egr1, Zbtb17, Egr2, E2f1, Klf5, Sp5, Zfp281, Zfx, Wt1,

Egr3
metacluster_1/pattern_2 # seqlets: 2802 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_3 # seqlets: 1625 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf1, Jdp2, Creb5, Atf7, Crem, Atf2, Tfe3, Tfec, Srebf1,

Usf1, Tfeb, Mlx, Mitf, Xbp1, Rxrb, Arntl, Srebf2, Bhlhe40, Usf2, Clock,

Atf3, Creb3l2, Tef, Nfil3, Jun, Mafb, Fosl2, Dbp, Npas2, Hlf
metacluster_1/pattern_4 # seqlets: 1240 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1094 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_6 # seqlets: 1019 SequenceContrib ScoresHyp_Contrib Scores
Mxi1, Rfx1
metacluster_1/pattern_7 # seqlets: 1008 SequenceContrib ScoresHyp_Contrib Scores
Bach2, Jund, Fos, Nfe2, Fosl1, Nfe2l2, Fosb, Junb, Bach1, Batf,

Mafk, Mafa
metacluster_1/pattern_8 # seqlets: 906 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42, Maz, Klf15
metacluster_1/pattern_9 # seqlets: 735 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Irf7, Prdm1, Irf9, Stat2, Stat1, Irf3
metacluster_1/pattern_10 # seqlets: 711 SequenceContrib ScoresHyp_Contrib Scores
Gata4, Gata1, Gata2, Gata3, Tal1, Mecom, Gata6, Gata5
metacluster_1/pattern_11 # seqlets: 463 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_1/pattern_12 # seqlets: 462 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb
metacluster_1/pattern_13 # seqlets: 378 SequenceContrib ScoresHyp_Contrib Scores
Nfkb1, Rela, Nfkb2, Relb, Rel
metacluster_1/pattern_14 # seqlets: 299 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_15 # seqlets: 153 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_16 # seqlets: 110 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_17 # seqlets: 60 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2
metacluster_1/pattern_18 # seqlets: 35 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #144
TF NamePattern(s)
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00124343
metacluster_1/pattern_180.0378504
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.05204299999999999
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0378504
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0013274
metacluster_1/pattern_180.0378504
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_02.8139499999999997e-05
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000315656
metacluster_1/pattern_180.0378504
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0378504
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000478521
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0130322
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0418981
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0436149
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0010107999999999998
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0571044
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00938066
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
metacluster_1/pattern_180.0378504
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0013274
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00187816
metacluster_1/pattern_90.0198685
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.035031900000000005
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00811911
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.035031900000000005
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.023099599999999998
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.024741700000000002
metacluster_1/pattern_91.6659e-05
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.026300999999999998
metacluster_1/pattern_90.0138035
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.057677
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0284055
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0375035
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_11.5632299999999997e-06
metacluster_1/pattern_64.14971e-05
metacluster_1/pattern_81.9729e-05
metacluster_1/pattern_180.00392063
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00202721
metacluster_1/pattern_60.0173002
metacluster_1/pattern_80.05580740000000001
metacluster_1/pattern_180.0491637
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_15.71346e-06
metacluster_1/pattern_60.00045373900000000004
metacluster_1/pattern_80.000244585
metacluster_1/pattern_180.0378504
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00080701
metacluster_1/pattern_60.00143375
metacluster_1/pattern_83.05862e-05
metacluster_1/pattern_180.0253475
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_12.32802e-05
metacluster_1/pattern_60.00272075
metacluster_1/pattern_80.0175802
metacluster_1/pattern_180.05204299999999999
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000716505
metacluster_1/pattern_180.00595288
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000818665
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000818665
metacluster_1/pattern_60.0109214
metacluster_1/pattern_180.05204299999999999
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016767400000000002
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0013359
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.018541299999999997
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.05858680000000001
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.053775300000000005
metacluster_1/pattern_60.016149700000000003
metacluster_1/pattern_80.046853399999999996
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00352633
metacluster_1/pattern_60.018822099999999998
metacluster_1/pattern_80.00725497
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0538779
metacluster_1/pattern_60.059814400000000004
metacluster_1/pattern_80.024449400000000003
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0101975
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.018541299999999997
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.018541299999999997
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0285118
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0285118
metacluster_1/pattern_60.018822099999999998
metacluster_1/pattern_80.05580740000000001
metacluster_1/pattern_140.05838430000000001
metacluster_1/pattern_180.0378504
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.053775300000000005
metacluster_1/pattern_60.00998193
metacluster_1/pattern_80.014956299999999999
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.05858680000000001
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_24.06236e-14
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_23.7719400000000004e-08
metacluster_1/pattern_60.0584072
metacluster_1/pattern_80.05580740000000001
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00330252
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.015353700000000001
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0104571
metacluster_1/pattern_70.000216127
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00330252
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00455743
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0104571
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00528069
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.022521799999999998
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_30.024184599999999997
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0336329
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0144244
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0167899
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_30.011390899999999999
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_30.015353700000000001
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.013715600000000001
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.01372
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0336329
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.014515799999999999
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_30.030610599999999998
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.030176400000000003
metacluster_1/pattern_60.03490530000000001
metacluster_1/pattern_80.018741999999999998
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0167899
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0341841
metacluster_1/pattern_77.718840000000001e-05
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0190722
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_30.019778099999999996
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.022521799999999998
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_30.026026499999999998
metacluster_1/pattern_70.0393797
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.030176400000000003
metacluster_1/pattern_70.0324723
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.04333680000000001
metacluster_1/pattern_70.000966967
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0463375
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0494955
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0524485
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_42.07886e-09
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_44.96499e-06
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_47.02285e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_49.228760000000001e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000111998
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_55.4412400000000006e-08
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0172158
metacluster_1/pattern_80.014956299999999999
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.059814400000000004
metacluster_1/pattern_80.0007922319999999999
metacluster_1/pattern_152.26886e-10
metacluster_1/pattern_160.00942773
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_77.187600000000001e-07
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0012747
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_74.3331900000000004e-06
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_72.36907e-05
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.014037200000000001
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_74.5803900000000004e-05
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_74.5803900000000004e-05
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0152153
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000216127
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0105692
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0324723
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0194218
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_81.9729e-05
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_86.48309e-05
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0175802
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026888299999999997
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_80.05580740000000001
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_95.69357e-11
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000535839
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_98.95223e-05
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00010538399999999999
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000535839
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00126609
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00145708
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0138035
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00514087
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00556311
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00044055900000000004
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0450086
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00081818
Mecom
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0076961
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0246488
Gata5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0372356
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_114.4958800000000003e-20
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_116.99826e-20
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_115.7918e-12
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00258867
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00979585
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00620637
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00685294
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_138.50007e-07
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_133.68803e-05
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_136.93127e-06
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_138.330780000000001e-05
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00517457
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_141.62149e-06
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00827085
metacluster_1/pattern_160.049850099999999994
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_158.214939999999999e-08
metacluster_1/pattern_160.0476039
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0005649730000000001
metacluster_1/pattern_160.00902036
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00528189
metacluster_1/pattern_160.00942773
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0122456
metacluster_1/pattern_160.00154296
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000153084
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #82
TF NameModiscoHomer
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0010107999999999998
Pattern NameHomerSignificance
motif2.motif0.000439214
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
Pattern NameHomerSignificance
motif2.motif0.00033502900000000003
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000216127
Pattern NameHomerSignificance
motif7.motif0.0384345
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00811911
Pattern NameHomerSignificance
motif2.motif0.00335257
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_136.93127e-06
Pattern NameHomerSignificance
motif17.motif0.0005070130000000001
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0104571
metacluster_1/pattern_70.000216127
Pattern NameHomerSignificance
motif7.motif0.00254877
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.05858680000000001
Pattern NameHomerSignificance
motif3.motif0.00181269
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0013274
Pattern NameHomerSignificance
motif2.motif0.00056187
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0152153
Pattern NameHomerSignificance
motif7.motif0.0241303
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_49.228760000000001e-06
Pattern NameHomerSignificance
motif13.motif0.00699722
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_15.71346e-06
metacluster_1/pattern_60.00045373900000000004
metacluster_1/pattern_80.000244585
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif3.motif0.000135063
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0538779
metacluster_1/pattern_60.059814400000000004
metacluster_1/pattern_80.024449400000000003
Pattern NameHomerSignificance
motif3.motif0.038847
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0194218
Pattern NameHomerSignificance
motif7.motif0.027315499999999996
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif2.motif0.00108132
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0436149
Pattern NameHomerSignificance
motif2.motif0.05437859999999999
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif2.motif0.000439214
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_24.06236e-14
Pattern NameHomerSignificance
motif1.motif0.0005521090000000001
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00352633
metacluster_1/pattern_60.018822099999999998
metacluster_1/pattern_80.00725497
Pattern NameHomerSignificance
motif3.motif0.00269155
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.035031900000000005
Pattern NameHomerSignificance
motif2.motif0.0164375
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0013359
Pattern NameHomerSignificance
motif3.motif0.0008763880000000001
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.04333680000000001
metacluster_1/pattern_70.000966967
Pattern NameHomerSignificance
motif7.motif0.00220476
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00202721
metacluster_1/pattern_60.0173002
metacluster_1/pattern_80.05580740000000001
metacluster_1/pattern_180.0491637
Pattern NameHomerSignificance
motif3.motif0.00797644
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0012747
Pattern NameHomerSignificance
motif7.motif0.00802981
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_11.5632299999999997e-06
metacluster_1/pattern_64.14971e-05
metacluster_1/pattern_81.9729e-05
metacluster_1/pattern_180.00392063
Pattern NameHomerSignificance
motif3.motif0.000135063
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif2.motif0.00041227300000000006
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000111998
Pattern NameHomerSignificance
motif13.motif0.00699722
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_47.02285e-06
Pattern NameHomerSignificance
motif13.motif0.00267339
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000818665
Pattern NameHomerSignificance
motif3.motif0.00034545800000000004
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_80.05580740000000001
Pattern NameHomerSignificance
motif3.motif0.00444589
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000478521
Pattern NameHomerSignificance
motif2.motif0.000542106
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_115.7918e-12
Pattern NameHomerSignificance
motif5.motif7.96747e-05
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_114.4958800000000003e-20
Pattern NameHomerSignificance
motif5.motif1.09808e-06
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_138.50007e-07
Pattern NameHomerSignificance
motif17.motif7.06943e-05
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000315656
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif2.motif7.28259e-05
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.014037200000000001
Pattern NameHomerSignificance
motif7.motif0.044248699999999995
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_116.99826e-20
Pattern NameHomerSignificance
motif5.motif1.13181e-05
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_72.36907e-05
Pattern NameHomerSignificance
motif7.motif0.0221881
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0324723
Pattern NameHomerSignificance
motif7.motif0.052389599999999995
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_77.187600000000001e-07
Pattern NameHomerSignificance
motif7.motif0.00808128
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0571044
Pattern NameHomerSignificance
motif2.motif0.00278666
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00124343
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif2.motif0.00033502900000000003
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0130322
Pattern NameHomerSignificance
motif2.motif0.00611968
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.057677
Pattern NameHomerSignificance
motif2.motif0.0205069
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_138.330780000000001e-05
Pattern NameHomerSignificance
motif17.motif7.06943e-05
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_55.4412400000000006e-08
Pattern NameHomerSignificance
motif10.motif0.000141645
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000716505
metacluster_1/pattern_180.00595288
Pattern NameHomerSignificance
motif3.motif0.000135063
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
Pattern NameHomerSignificance
motif2.motif0.00033502900000000003
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_02.8139499999999997e-05
Pattern NameHomerSignificance
motif2.motif0.00053838
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0285118
Pattern NameHomerSignificance
motif3.motif0.0575972
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.018541299999999997
Pattern NameHomerSignificance
motif3.motif0.00444589
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_30.026026499999999998
metacluster_1/pattern_70.0393797
Pattern NameHomerSignificance
motif7.motif0.0291952
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00187816
metacluster_1/pattern_90.0198685
Pattern NameHomerSignificance
motif2.motif0.05437859999999999
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0341841
metacluster_1/pattern_77.718840000000001e-05
Pattern NameHomerSignificance
motif7.motif0.00263688
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_44.96499e-06
Pattern NameHomerSignificance
motif13.motif0.00267339
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0104571
Pattern NameHomerSignificance
motif18.motif0.03500109999999999
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_133.68803e-05
Pattern NameHomerSignificance
motif17.motif0.000415502
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00517457
Pattern NameHomerSignificance
motif17.motif0.0312442
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00938066
Pattern NameHomerSignificance
motif2.motif0.0124018
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.05204299999999999
Pattern NameHomerSignificance
motif2.motif0.000439214
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_42.07886e-09
Pattern NameHomerSignificance
motif13.motif0.0008268710000000001
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_23.7719400000000004e-08
metacluster_1/pattern_60.0584072
metacluster_1/pattern_80.05580740000000001
Pattern NameHomerSignificance
motif1.motif0.00118826
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_141.62149e-06
Pattern NameHomerSignificance
motif15.motif0.0016649999999999998
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00136197
Pattern NameHomerSignificance
motif2.motif0.00061024
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000818665
metacluster_1/pattern_60.0109214
metacluster_1/pattern_180.05204299999999999
Pattern NameHomerSignificance
motif3.motif0.000639735
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_12.32802e-05
metacluster_1/pattern_60.00272075
metacluster_1/pattern_80.0175802
metacluster_1/pattern_180.05204299999999999
Pattern NameHomerSignificance
motif3.motif0.000135063
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00126769
metacluster_1/pattern_180.0418981
Pattern NameHomerSignificance
motif2.motif0.000282822
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016767400000000002
Pattern NameHomerSignificance
motif3.motif0.030508499999999997
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_74.5803900000000004e-05
Pattern NameHomerSignificance
motif7.motif0.0190375
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.023099599999999998
Pattern NameHomerSignificance
motif2.motif0.055695299999999996
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_74.3331900000000004e-06
Pattern NameHomerSignificance
motif7.motif3.0604699999999995e-05
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0105692
Pattern NameHomerSignificance
motif7.motif0.03807990000000001
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00080701
metacluster_1/pattern_60.00143375
metacluster_1/pattern_83.05862e-05
metacluster_1/pattern_180.0253475
Pattern NameHomerSignificance
motif3.motif0.00342503
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0101975
Pattern NameHomerSignificance
motif3.motif0.0008763880000000001
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.053775300000000005
metacluster_1/pattern_60.016149700000000003
metacluster_1/pattern_80.046853399999999996
Pattern NameHomerSignificance
motif3.motif0.00527415
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.015353700000000001
Pattern NameHomerSignificance
motif18.motif0.03500109999999999
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.035031900000000005
Pattern NameHomerSignificance
motif2.motif0.027684300000000002
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_74.5803900000000004e-05
Pattern NameHomerSignificance
motif7.motif0.00295125
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0013274
metacluster_1/pattern_180.0378504
Pattern NameHomerSignificance
motif2.motif0.00033502900000000003
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.030176400000000003
metacluster_1/pattern_70.0324723
Pattern NameHomerSignificance
motif7.motif0.0291952
motif18.motif0.03500109999999999
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00330252
Pattern NameHomerSignificance
motif6.motif0.0462782
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.018541299999999997
Pattern NameHomerSignificance
motif3.motif0.030508499999999997
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.018541299999999997
Pattern NameHomerSignificance
motif3.motif0.031153899999999998
Unique TF-MoDISco TFs: #62
TF NameModiscoHomer
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0375035
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_98.95223e-05
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_30.019778099999999996
Absent
Gata5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0372356
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0524485
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00010538399999999999
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0190722
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0336329
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00827085
metacluster_1/pattern_160.049850099999999994
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000535839
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00556311
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000153084
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_30.030610599999999998
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00455743
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.01372
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00528069
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0285118
metacluster_1/pattern_60.018822099999999998
metacluster_1/pattern_80.05580740000000001
metacluster_1/pattern_140.05838430000000001
metacluster_1/pattern_180.0378504
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000535839
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0005649730000000001
metacluster_1/pattern_160.00902036
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00528189
metacluster_1/pattern_160.00942773
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0122456
metacluster_1/pattern_160.00154296
Absent
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0450086
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0167899
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.059814400000000004
metacluster_1/pattern_80.0007922319999999999
metacluster_1/pattern_152.26886e-10
metacluster_1/pattern_160.00942773
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00126609
Absent
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00044055900000000004
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.024741700000000002
metacluster_1/pattern_91.6659e-05
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0167899
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00685294
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_30.024184599999999997
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_158.214939999999999e-08
metacluster_1/pattern_160.0476039
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.05858680000000001
Absent
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00514087
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.022521799999999998
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00145708
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.030176400000000003
metacluster_1/pattern_60.03490530000000001
metacluster_1/pattern_80.018741999999999998
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.053775300000000005
metacluster_1/pattern_60.00998193
metacluster_1/pattern_80.014956299999999999
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00330252
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.014515799999999999
Absent
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_86.48309e-05
Absent
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00081818
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_30.015353700000000001
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026888299999999997
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0336329
Absent
Mecom
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0076961
Absent
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0246488
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00979585
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.022521799999999998
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0284055
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.026300999999999998
metacluster_1/pattern_90.0138035
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_81.9729e-05
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_95.69357e-11
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0138035
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0144244
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_30.011390899999999999
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0494955
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0463375
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00258867
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00620637
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0175802
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.013715600000000001
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0172158
metacluster_1/pattern_80.014956299999999999
Absent
Unique Homer TFs: #5
TF NameModiscoHomer
E2f6Absent
Pattern NameHomerSignificance
motif3.motif0.0136724
Zbtb1Absent
Pattern NameHomerSignificance
motif3.motif0.030508499999999997
Mzf1Absent
Pattern NameHomerSignificance
motif17.motif0.0462091
E2f3Absent
Pattern NameHomerSignificance
motif3.motif0.0575972
E2f7Absent
Pattern NameHomerSignificance
motif3.motif0.00444589