# Parameters
data_name = "naiveCD8;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_1-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_1-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:41:46,568 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	naive CD8
Cell Group	T cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	93898	70870	11.888	53664345	7669787	0.143	5612991	0.1046	16388356	0.3055

Modelling Metadata

Metric	Value
auPRC	0.5585
Calibrated Recall at 50% FDR	0.26
Number of Positive Examples in Test Data	76284
Number of Negative Examples in Test Data	7994567
Imbalance Ratio in Test Data	0.0095
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #18

Pattern Name	TF Name(s)	Modisco
metacluster_0/pattern_0 # seqlets: 5944 SequenceContrib ScoresHyp_Contrib Scores	Ets1, Erg, Etv4, Fli1, Elk1, Gabpa, Etv2, Spi1, Elk4, Elk3, Etv5, Etv6, Fev, Elf2, Etv1, Spib, Etv3, XP_911724.4, Elf1, Ehf, Elf4, Irf8, Elf5, Irf4, Spic, Elf3, Spdef, Zscan10, Stat3
metacluster_0/pattern_1 # seqlets: 4278 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_0/pattern_2 # seqlets: 3045 SequenceContrib ScoresHyp_Contrib Scores	Sp4, Sp2, Sp3, Klf3, Sp1, Klf6, E2f4, Klf7, Klf4, Klf8, Klf1, Klf12, Egr1, Zbtb17, Egr2, E2f1, Klf5, Sp5, Zfp281, Zfx, Zfp740, Egr3
metacluster_0/pattern_3 # seqlets: 1431 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_0/pattern_4 # seqlets: 1142 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_0/pattern_5 # seqlets: 1126 SequenceContrib ScoresHyp_Contrib Scores	Irf1, Irf2, Irf7, Prdm1, Stat1, Irf9, Irf3, Stat2, Batf3, Irf5
metacluster_0/pattern_6 # seqlets: 994 SequenceContrib ScoresHyp_Contrib Scores	Creb1, Creb5, Atf7, Atf2, Jdp2, Atf1, Crem, Jun, Nfil3, Tef, Mafb, Dbp, Hlf, Gmeb2, Fosl1, Cebpb, Atf3, Cebpa, Junb, Jund, Gmeb1, Rxrb, Cebpd, Cebpg, Fosl2, Esr2
metacluster_0/pattern_7 # seqlets: 750 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_0/pattern_8 # seqlets: 654 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfp42, Maz, Wt1, Mxi1, Klf15, Usf2
metacluster_0/pattern_9 # seqlets: 631 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_0/pattern_10 # seqlets: 557 SequenceContrib ScoresHyp_Contrib Scores	Usf1, Tfec, Tfeb, Arntl, Mitf, Srebf1, Bhlhe40, Tfe3, Clock, Mlx, Arnt, Npas2, Creb3l2, Srebf2, Tcfl5, Bhlhe41, Xbp1, Mycn, Max, Mlxip, Hes1
metacluster_0/pattern_11 # seqlets: 340 SequenceContrib ScoresHyp_Contrib Scores	Rfx3, Rfx2, Rfx1, Rfx4, Rfx6, Rfx7
metacluster_0/pattern_12 # seqlets: 334 SequenceContrib ScoresHyp_Contrib Scores	Fos, Fosb, Batf, Bach2, Nfe2l2, Bach1, Nfe2, Mafa, Mafk
metacluster_0/pattern_13 # seqlets: 302 SequenceContrib ScoresHyp_Contrib Scores	Tcf7l2, Tcf7l1, Lef1, Tcf3, Tcf7
metacluster_0/pattern_14 # seqlets: 168 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_15 # seqlets: 144 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33
metacluster_0/pattern_16 # seqlets: 134 SequenceContrib ScoresHyp_Contrib Scores	Nfib, Nfia, Nfic
metacluster_0/pattern_17 # seqlets: 41 SequenceContrib ScoresHyp_Contrib Scores	Pou2f2, Pou2f1

Click here for Motifs by TF-MoDISco: #158

TF Name	Pattern(s)
Ets1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Erg	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Etv4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Fli1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Elk1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Gabpa	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Etv2	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00031109299999999997
Spi1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.030114799999999997
Elk4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00251489
Elk3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Etv5	Pattern Name Modisco Significance metacluster_0/pattern_0 0.000866967
Etv6	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Fev	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Elf2	Pattern Name Modisco Significance metacluster_0/pattern_0 0.0096412
Etv1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Spib	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815 metacluster_0/pattern_5 0.00356317
Etv3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
XP_911724.4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815
Elf1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00392359
Ehf	Pattern Name Modisco Significance metacluster_0/pattern_0 0.011912299999999999
Elf4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00577577
Irf8	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00897257 metacluster_0/pattern_5 4.52506e-06
Elf5	Pattern Name Modisco Significance metacluster_0/pattern_0 0.030114799999999997
Irf4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.011001899999999998 metacluster_0/pattern_5 0.00766783
Spic	Pattern Name Modisco Significance metacluster_0/pattern_0 0.0485537 metacluster_0/pattern_5 0.059330799999999996
Elf3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.024041099999999996
Spdef	Pattern Name Modisco Significance metacluster_0/pattern_0 0.024041099999999996
Zscan10	Pattern Name Modisco Significance metacluster_0/pattern_0 0.030114799999999997
Stat3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.0528087
Ctcf	Pattern Name Modisco Significance metacluster_0/pattern_1 9.52016e-16
Ctcfl	Pattern Name Modisco Significance metacluster_0/pattern_1 5.810230000000001e-08
Sp4	Pattern Name Modisco Significance metacluster_0/pattern_2 0.00117419
Sp2	Pattern Name Modisco Significance metacluster_0/pattern_2 3.3636900000000002e-06 metacluster_0/pattern_8 2.09032e-05
Sp3	Pattern Name Modisco Significance metacluster_0/pattern_2 5.922080000000001e-06 metacluster_0/pattern_8 0.000222585
Klf3	Pattern Name Modisco Significance metacluster_0/pattern_2 5.922080000000001e-06 metacluster_0/pattern_8 0.0238535
Sp1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000393283 metacluster_0/pattern_8 0.000119693
Klf6	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000393283
E2f4	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000393283
Klf7	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000409205
Klf4	Pattern Name Modisco Significance metacluster_0/pattern_2 0.00940505
Klf8	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0007287410000000001
Klf1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0360797
Klf12	Pattern Name Modisco Significance metacluster_0/pattern_2 0.011554799999999999
Egr1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.038022 metacluster_0/pattern_8 0.0593025
Zbtb17	Pattern Name Modisco Significance metacluster_0/pattern_2 0.00593273 metacluster_0/pattern_8 0.00917025
Egr2	Pattern Name Modisco Significance metacluster_0/pattern_2 0.038022 metacluster_0/pattern_8 0.0498432
E2f1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0100637
Klf5	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0117272
Sp5	Pattern Name Modisco Significance metacluster_0/pattern_2 0.017734299999999998
Zfp281	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0222837
Zfx	Pattern Name Modisco Significance metacluster_0/pattern_2 0.037775199999999995 metacluster_0/pattern_8 0.0593025
Zfp740	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0505366
Egr3	Pattern Name Modisco Significance metacluster_0/pattern_2 0.051816499999999995
Nrf1	Pattern Name Modisco Significance metacluster_0/pattern_3 2.70837e-08
Nfyb	Pattern Name Modisco Significance metacluster_0/pattern_4 4.7265199999999997e-14
Nfyc	Pattern Name Modisco Significance metacluster_0/pattern_4 2.36113e-10
Nfya	Pattern Name Modisco Significance metacluster_0/pattern_4 2.36539e-09
Foxi1	Pattern Name Modisco Significance metacluster_0/pattern_4 3.2095e-06
Pbx3	Pattern Name Modisco Significance metacluster_0/pattern_4 3.85634e-06
Irf1	Pattern Name Modisco Significance metacluster_0/pattern_5 1.31415e-12
Irf2	Pattern Name Modisco Significance metacluster_0/pattern_5 0.000568371
Irf7	Pattern Name Modisco Significance metacluster_0/pattern_5 7.16332e-06
Prdm1	Pattern Name Modisco Significance metacluster_0/pattern_5 7.50083e-05
Stat1	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00015265
Irf9	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00044736099999999996
Irf3	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00186086
Stat2	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00356317
Batf3	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00905231
Irf5	Pattern Name Modisco Significance metacluster_0/pattern_5 0.052246
Creb1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00018203 metacluster_0/pattern_10 0.0510084
Creb5	Pattern Name Modisco Significance metacluster_0/pattern_6 7.78005e-05
Atf7	Pattern Name Modisco Significance metacluster_0/pattern_6 0.000147869
Atf2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.000732582
Jdp2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.000845455 metacluster_0/pattern_12 3.65223e-05
Atf1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0245052 metacluster_0/pattern_10 0.012859200000000001
Crem	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00195196
Jun	Pattern Name Modisco Significance metacluster_0/pattern_6 0.013155600000000002 metacluster_0/pattern_12 0.0442296
Nfil3	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0401218
Tef	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00460787
Mafb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00679703
Dbp	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00921274 metacluster_0/pattern_10 0.0489249
Hlf	Pattern Name Modisco Significance metacluster_0/pattern_6 0.012639399999999999 metacluster_0/pattern_10 0.0503164
Gmeb2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0129345
Fosl1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0163197 metacluster_0/pattern_12 0.0471042
Cebpb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.054912
Atf3	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0417555 metacluster_0/pattern_12 1.9703299999999998e-05
Cebpa	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0245439
Junb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.027901799999999997 metacluster_0/pattern_12 0.0471661
Jund	Pattern Name Modisco Significance metacluster_0/pattern_6 0.027901799999999997 metacluster_0/pattern_12 0.00461226
Gmeb1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.027901799999999997
Rxrb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0300152
Cebpd	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0315668
Cebpg	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0581974
Fosl2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.043850400000000005 metacluster_0/pattern_12 1.41941e-05
Esr2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.054249599999999995
Runx1	Pattern Name Modisco Significance metacluster_0/pattern_7 0.00022239799999999998
Runx2	Pattern Name Modisco Significance metacluster_0/pattern_7 0.00647218
Runx3	Pattern Name Modisco Significance metacluster_0/pattern_7 0.000667658
Cbfb	Pattern Name Modisco Significance metacluster_0/pattern_7 0.00206419
Gfi1b	Pattern Name Modisco Significance metacluster_0/pattern_7 0.0427164
Taf1	Pattern Name Modisco Significance metacluster_0/pattern_8 3.96707e-06
Yy1	Pattern Name Modisco Significance metacluster_0/pattern_8 7.122960000000001e-06
Zfp42	Pattern Name Modisco Significance metacluster_0/pattern_8 0.008926799999999999
Maz	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0177165
Wt1	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0177165
Mxi1	Pattern Name Modisco Significance metacluster_0/pattern_8 0.026047900000000006
Klf15	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0498432
Usf2	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0498432 metacluster_0/pattern_10 0.00169383
Zfp143	Pattern Name Modisco Significance metacluster_0/pattern_9 2.4593599999999998e-20
Thap11	Pattern Name Modisco Significance metacluster_0/pattern_9 7.320110000000001e-20
Tbx2	Pattern Name Modisco Significance metacluster_0/pattern_9 3.32659e-14
Usf1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00327151
Tfec	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00162802
Tfeb	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0010677
Arntl	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00647026
Mitf	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0010677
Srebf1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0031945999999999997
Bhlhe40	Pattern Name Modisco Significance metacluster_0/pattern_10 0.014206700000000001
Tfe3	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00162802
Clock	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0510084
Mlx	Pattern Name Modisco Significance metacluster_0/pattern_10 0.014702200000000002
Arnt	Pattern Name Modisco Significance metacluster_0/pattern_10 0.039653100000000004
Npas2	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00176281
Creb3l2	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0356355
Srebf2	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0040241
Tcfl5	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00530016
Bhlhe41	Pattern Name Modisco Significance metacluster_0/pattern_10 0.016822999999999998
Xbp1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.026551799999999997
Mycn	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0578624
Max	Pattern Name Modisco Significance metacluster_0/pattern_10 0.05418340000000001
Mlxip	Pattern Name Modisco Significance metacluster_0/pattern_10 0.050427099999999996
Hes1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0510084
Rfx3	Pattern Name Modisco Significance metacluster_0/pattern_11 0.00390068
Rfx2	Pattern Name Modisco Significance metacluster_0/pattern_11 4.03622e-08
Rfx1	Pattern Name Modisco Significance metacluster_0/pattern_11 1.33891e-08
Rfx4	Pattern Name Modisco Significance metacluster_0/pattern_11 0.00010777299999999999
Rfx6	Pattern Name Modisco Significance metacluster_0/pattern_11 0.000666615
Rfx7	Pattern Name Modisco Significance metacluster_0/pattern_11 0.00154081
Fos	Pattern Name Modisco Significance metacluster_0/pattern_12 4.94711e-06
Fosb	Pattern Name Modisco Significance metacluster_0/pattern_12 1.3176400000000001e-05
Batf	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00568982
Bach2	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00220252
Nfe2l2	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00480695
Bach1	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00441443
Nfe2	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00441443
Mafa	Pattern Name Modisco Significance metacluster_0/pattern_12 0.042031900000000004
Mafk	Pattern Name Modisco Significance metacluster_0/pattern_12 0.0471661
Tcf7l2	Pattern Name Modisco Significance metacluster_0/pattern_13 0.00519863
Tcf7l1	Pattern Name Modisco Significance metacluster_0/pattern_13 0.0009343110000000001
Lef1	Pattern Name Modisco Significance metacluster_0/pattern_13 9.63546e-06
Tcf3	Pattern Name Modisco Significance metacluster_0/pattern_13 9.01052e-05
Tcf7	Pattern Name Modisco Significance metacluster_0/pattern_13 0.00809135
Zbtb33	Pattern Name Modisco Significance metacluster_0/pattern_15 0.00013592200000000002
Nfib	Pattern Name Modisco Significance metacluster_0/pattern_16 3.6431999999999997e-07
Nfia	Pattern Name Modisco Significance metacluster_0/pattern_16 7.113720000000001e-05
Nfic	Pattern Name Modisco Significance metacluster_0/pattern_16 0.00295742
Pou2f2	Pattern Name Modisco Significance metacluster_0/pattern_17 0.00297181
Pou2f1	Pattern Name Modisco Significance metacluster_0/pattern_17 0.027610400000000004

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #82

TF Name	Modisco	Homer
Atf3	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0417555 metacluster_0/pattern_12 1.9703299999999998e-05	Pattern Name Homer Significance motif8.motif 0.0423906
Usf2	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0498432 metacluster_0/pattern_10 0.00169383	Pattern Name Homer Significance motif8.motif 0.0183338
Sp3	Pattern Name Modisco Significance metacluster_0/pattern_2 5.922080000000001e-06 metacluster_0/pattern_8 0.000222585	Pattern Name Homer Significance motif3.motif 6.80023e-06
Ctcfl	Pattern Name Modisco Significance metacluster_0/pattern_1 5.810230000000001e-08	Pattern Name Homer Significance motif1.motif 0.00114609
Klf1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0360797	Pattern Name Homer Significance motif3.motif 0.025698099999999998
Tfeb	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0010677	Pattern Name Homer Significance motif8.motif 0.027833499999999997
Spi1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.030114799999999997	Pattern Name Homer Significance motif2.motif 0.0365978
Foxi1	Pattern Name Modisco Significance metacluster_0/pattern_4 3.2095e-06	Pattern Name Homer Significance motif6.motif 2.36459e-05
E2f4	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000393283	Pattern Name Homer Significance motif3.motif 0.00332653
Etv6	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.0099119
Zfp143	Pattern Name Modisco Significance metacluster_0/pattern_9 2.4593599999999998e-20	Pattern Name Homer Significance motif4.motif 2.4048799999999998e-08
Klf3	Pattern Name Modisco Significance metacluster_0/pattern_2 5.922080000000001e-06 metacluster_0/pattern_8 0.0238535	Pattern Name Homer Significance motif3.motif 0.00017036599999999997
Tbx2	Pattern Name Modisco Significance metacluster_0/pattern_9 3.32659e-14	Pattern Name Homer Significance motif4.motif 2.06054e-06
Creb1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00018203 metacluster_0/pattern_10 0.0510084	Pattern Name Homer Significance motif8.motif 0.00985042
Usf1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00327151	Pattern Name Homer Significance motif8.motif 0.0071396
Arntl	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00647026	Pattern Name Homer Significance motif8.motif 0.05741990000000001
Mlx	Pattern Name Modisco Significance metacluster_0/pattern_10 0.014702200000000002	Pattern Name Homer Significance motif8.motif 0.0484028
Sp2	Pattern Name Modisco Significance metacluster_0/pattern_2 3.3636900000000002e-06 metacluster_0/pattern_8 2.09032e-05	Pattern Name Homer Significance motif3.motif 1.54554e-05
Spdef	Pattern Name Modisco Significance metacluster_0/pattern_0 0.024041099999999996	Pattern Name Homer Significance motif2.motif 0.027137
Srebf1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0031945999999999997	Pattern Name Homer Significance motif8.motif 0.0497916
Ctcf	Pattern Name Modisco Significance metacluster_0/pattern_1 9.52016e-16	Pattern Name Homer Significance motif1.motif 0.000622585
Elf2	Pattern Name Modisco Significance metacluster_0/pattern_0 0.0096412	Pattern Name Homer Significance motif2.motif 0.031169799999999998
XP_911724.4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00287751
Elf5	Pattern Name Modisco Significance metacluster_0/pattern_0 0.030114799999999997	Pattern Name Homer Significance motif2.motif 0.0325639
Klf7	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000409205	Pattern Name Homer Significance motif3.motif 0.00024436
Egr2	Pattern Name Modisco Significance metacluster_0/pattern_2 0.038022 metacluster_0/pattern_8 0.0498432	Pattern Name Homer Significance motif3.motif 0.0364564
Sp5	Pattern Name Modisco Significance metacluster_0/pattern_2 0.017734299999999998	Pattern Name Homer Significance motif3.motif 0.0376265
Pbx3	Pattern Name Modisco Significance metacluster_0/pattern_4 3.85634e-06	Pattern Name Homer Significance motif6.motif 0.000166845
Mitf	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0010677	Pattern Name Homer Significance motif8.motif 0.0467158
Zbtb33	Pattern Name Modisco Significance metacluster_0/pattern_15 0.00013592200000000002	Pattern Name Homer Significance motif9.motif 9.317559999999999e-05
Nfyb	Pattern Name Modisco Significance metacluster_0/pattern_4 4.7265199999999997e-14	Pattern Name Homer Significance motif6.motif 1.1745099999999999e-08
Klf5	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0117272	Pattern Name Homer Significance motif3.motif 0.00781515
Xbp1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.026551799999999997	Pattern Name Homer Significance motif8.motif 0.05741990000000001
Fli1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00212991
Clock	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0510084	Pattern Name Homer Significance motif8.motif 0.0467158
Crem	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00195196	Pattern Name Homer Significance motif8.motif 0.0497916
Etv4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00212991
Zfp42	Pattern Name Modisco Significance metacluster_0/pattern_8 0.008926799999999999	Pattern Name Homer Significance motif11.motif 0.00509907
Erg	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00218698
Etv2	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00031109299999999997	Pattern Name Homer Significance motif2.motif 1.24745e-05
Zbtb17	Pattern Name Modisco Significance metacluster_0/pattern_2 0.00593273 metacluster_0/pattern_8 0.00917025	Pattern Name Homer Significance motif3.motif 0.023299200000000003
Nfyc	Pattern Name Modisco Significance metacluster_0/pattern_4 2.36113e-10	Pattern Name Homer Significance motif6.motif 6.53889e-06
Rxrb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0300152	Pattern Name Homer Significance motif8.motif 0.0385682
Elk4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00251489	Pattern Name Homer Significance motif2.motif 0.00212991
Etv1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00250638
Atf1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0245052 metacluster_0/pattern_10 0.012859200000000001	Pattern Name Homer Significance motif8.motif 0.0374591
Elk3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00194781
Ehf	Pattern Name Modisco Significance metacluster_0/pattern_0 0.011912299999999999	Pattern Name Homer Significance motif2.motif 0.011113799999999998
Fev	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00042765800000000003
Bhlhe40	Pattern Name Modisco Significance metacluster_0/pattern_10 0.014206700000000001	Pattern Name Homer Significance motif8.motif 0.050908999999999996
Jdp2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.000845455 metacluster_0/pattern_12 3.65223e-05	Pattern Name Homer Significance motif8.motif 0.0071396
Mafb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00679703	Pattern Name Homer Significance motif8.motif 0.027833499999999997
Elk1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00212991
Elf3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.024041099999999996	Pattern Name Homer Significance motif2.motif 0.027137
Srebf2	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0040241	Pattern Name Homer Significance motif8.motif 0.0365142
Atf7	Pattern Name Modisco Significance metacluster_0/pattern_6 0.000147869	Pattern Name Homer Significance motif8.motif 0.0071396
Tfec	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00162802	Pattern Name Homer Significance motif8.motif 0.0497916
Thap11	Pattern Name Modisco Significance metacluster_0/pattern_9 7.320110000000001e-20	Pattern Name Homer Significance motif4.motif 4.2802800000000005e-08
Ets1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00212991
Elf4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00577577	Pattern Name Homer Significance motif2.motif 0.0177683
Egr1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.038022 metacluster_0/pattern_8 0.0593025	Pattern Name Homer Significance motif3.motif 0.00781515
Tfe3	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00162802	Pattern Name Homer Significance motif8.motif 0.0421554
Creb5	Pattern Name Modisco Significance metacluster_0/pattern_6 7.78005e-05	Pattern Name Homer Significance motif8.motif 0.00168558
Gabpa	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00218698
Etv5	Pattern Name Modisco Significance metacluster_0/pattern_0 0.000866967	Pattern Name Homer Significance motif2.motif 0.0005287530000000001
E2f1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0100637	Pattern Name Homer Significance motif3.motif 0.036418900000000004
Sp4	Pattern Name Modisco Significance metacluster_0/pattern_2 0.00117419	Pattern Name Homer Significance motif3.motif 0.0195598
Sp1	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000393283 metacluster_0/pattern_8 0.000119693	Pattern Name Homer Significance motif3.motif 0.00781515
Etv3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815	Pattern Name Homer Significance motif2.motif 0.00287751
Creb3l2	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0356355	Pattern Name Homer Significance motif8.motif 0.0467158
Klf6	Pattern Name Modisco Significance metacluster_0/pattern_2 0.000393283	Pattern Name Homer Significance motif3.motif 0.00332653
Nrf1	Pattern Name Modisco Significance metacluster_0/pattern_3 2.70837e-08	Pattern Name Homer Significance motif7.motif 0.000911978
Fosl2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.043850400000000005 metacluster_0/pattern_12 1.41941e-05	Pattern Name Homer Significance motif8.motif 0.031729200000000006
Elf1	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00392359	Pattern Name Homer Significance motif2.motif 0.0009178789999999999
Yy1	Pattern Name Modisco Significance metacluster_0/pattern_8 7.122960000000001e-06	Pattern Name Homer Significance motif11.motif 0.00509907
Taf1	Pattern Name Modisco Significance metacluster_0/pattern_8 3.96707e-06	Pattern Name Homer Significance motif11.motif 0.019802599999999997
Nfya	Pattern Name Modisco Significance metacluster_0/pattern_4 2.36539e-09	Pattern Name Homer Significance motif6.motif 3.40371e-06
Atf2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.000732582	Pattern Name Homer Significance motif8.motif 0.0134004
Klf4	Pattern Name Modisco Significance metacluster_0/pattern_2 0.00940505	Pattern Name Homer Significance motif3.motif 0.0300779
Klf15	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0498432	Pattern Name Homer Significance motif3.motif 0.0468065
Klf8	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0007287410000000001	Pattern Name Homer Significance motif3.motif 0.0006495019999999999
Klf12	Pattern Name Modisco Significance metacluster_0/pattern_2 0.011554799999999999	Pattern Name Homer Significance motif3.motif 0.0157347

Unique TF-MoDISco TFs: #76

TF Name	Modisco	Homer
Cebpd	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0315668	Absent
Arnt	Pattern Name Modisco Significance metacluster_0/pattern_10 0.039653100000000004	Absent
Irf7	Pattern Name Modisco Significance metacluster_0/pattern_5 7.16332e-06	Absent
Pou2f1	Pattern Name Modisco Significance metacluster_0/pattern_17 0.027610400000000004	Absent
Max	Pattern Name Modisco Significance metacluster_0/pattern_10 0.05418340000000001	Absent
Wt1	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0177165	Absent
Jun	Pattern Name Modisco Significance metacluster_0/pattern_6 0.013155600000000002 metacluster_0/pattern_12 0.0442296	Absent
Stat1	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00015265	Absent
Mafk	Pattern Name Modisco Significance metacluster_0/pattern_12 0.0471661	Absent
Stat2	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00356317	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00530016	Absent
Zfp281	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0222837	Absent
Nfe2	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00441443	Absent
Zscan10	Pattern Name Modisco Significance metacluster_0/pattern_0 0.030114799999999997	Absent
Stat3	Pattern Name Modisco Significance metacluster_0/pattern_0 0.0528087	Absent
Npas2	Pattern Name Modisco Significance metacluster_0/pattern_10 0.00176281	Absent
Batf3	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00905231	Absent
Fosl1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0163197 metacluster_0/pattern_12 0.0471042	Absent
Irf1	Pattern Name Modisco Significance metacluster_0/pattern_5 1.31415e-12	Absent
Tef	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00460787	Absent
Junb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.027901799999999997 metacluster_0/pattern_12 0.0471661	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_0/pattern_10 0.016822999999999998	Absent
Zfp740	Pattern Name Modisco Significance metacluster_0/pattern_2 0.0505366	Absent
Prdm1	Pattern Name Modisco Significance metacluster_0/pattern_5 7.50083e-05	Absent
Esr2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.054249599999999995	Absent
Runx2	Pattern Name Modisco Significance metacluster_0/pattern_7 0.00647218	Absent
Mlxip	Pattern Name Modisco Significance metacluster_0/pattern_10 0.050427099999999996	Absent
Nfib	Pattern Name Modisco Significance metacluster_0/pattern_16 3.6431999999999997e-07	Absent
Tcf7l2	Pattern Name Modisco Significance metacluster_0/pattern_13 0.00519863	Absent
Mycn	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0578624	Absent
Gmeb2	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0129345	Absent
Nfil3	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0401218	Absent
Spib	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00167815 metacluster_0/pattern_5 0.00356317	Absent
Fos	Pattern Name Modisco Significance metacluster_0/pattern_12 4.94711e-06	Absent
Mafa	Pattern Name Modisco Significance metacluster_0/pattern_12 0.042031900000000004	Absent
Rfx1	Pattern Name Modisco Significance metacluster_0/pattern_11 1.33891e-08	Absent
Zfx	Pattern Name Modisco Significance metacluster_0/pattern_2 0.037775199999999995 metacluster_0/pattern_8 0.0593025	Absent
Tcf7	Pattern Name Modisco Significance metacluster_0/pattern_13 0.00809135	Absent
Gmeb1	Pattern Name Modisco Significance metacluster_0/pattern_6 0.027901799999999997	Absent
Lef1	Pattern Name Modisco Significance metacluster_0/pattern_13 9.63546e-06	Absent
Rfx6	Pattern Name Modisco Significance metacluster_0/pattern_11 0.000666615	Absent
Nfia	Pattern Name Modisco Significance metacluster_0/pattern_16 7.113720000000001e-05	Absent
Tcf7l1	Pattern Name Modisco Significance metacluster_0/pattern_13 0.0009343110000000001	Absent
Maz	Pattern Name Modisco Significance metacluster_0/pattern_8 0.0177165	Absent
Tcf3	Pattern Name Modisco Significance metacluster_0/pattern_13 9.01052e-05	Absent
Cebpb	Pattern Name Modisco Significance metacluster_0/pattern_6 0.054912	Absent
Egr3	Pattern Name Modisco Significance metacluster_0/pattern_2 0.051816499999999995	Absent
Rfx7	Pattern Name Modisco Significance metacluster_0/pattern_11 0.00154081	Absent
Runx3	Pattern Name Modisco Significance metacluster_0/pattern_7 0.000667658	Absent
Bach1	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00441443	Absent
Irf2	Pattern Name Modisco Significance metacluster_0/pattern_5 0.000568371	Absent
Fosb	Pattern Name Modisco Significance metacluster_0/pattern_12 1.3176400000000001e-05	Absent
Gfi1b	Pattern Name Modisco Significance metacluster_0/pattern_7 0.0427164	Absent
Cbfb	Pattern Name Modisco Significance metacluster_0/pattern_7 0.00206419	Absent
Hes1	Pattern Name Modisco Significance metacluster_0/pattern_10 0.0510084	Absent
Mxi1	Pattern Name Modisco Significance metacluster_0/pattern_8 0.026047900000000006	Absent
Pou2f2	Pattern Name Modisco Significance metacluster_0/pattern_17 0.00297181	Absent
Irf4	Pattern Name Modisco Significance metacluster_0/pattern_0 0.011001899999999998 metacluster_0/pattern_5 0.00766783	Absent
Irf5	Pattern Name Modisco Significance metacluster_0/pattern_5 0.052246	Absent
Nfic	Pattern Name Modisco Significance metacluster_0/pattern_16 0.00295742	Absent
Batf	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00568982	Absent
Rfx4	Pattern Name Modisco Significance metacluster_0/pattern_11 0.00010777299999999999	Absent
Irf3	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00186086	Absent
Rfx3	Pattern Name Modisco Significance metacluster_0/pattern_11 0.00390068	Absent
Nfe2l2	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00480695	Absent
Spic	Pattern Name Modisco Significance metacluster_0/pattern_0 0.0485537 metacluster_0/pattern_5 0.059330799999999996	Absent
Hlf	Pattern Name Modisco Significance metacluster_0/pattern_6 0.012639399999999999 metacluster_0/pattern_10 0.0503164	Absent
Runx1	Pattern Name Modisco Significance metacluster_0/pattern_7 0.00022239799999999998	Absent
Bach2	Pattern Name Modisco Significance metacluster_0/pattern_12 0.00220252	Absent
Jund	Pattern Name Modisco Significance metacluster_0/pattern_6 0.027901799999999997 metacluster_0/pattern_12 0.00461226	Absent
Cebpa	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0245439	Absent
Dbp	Pattern Name Modisco Significance metacluster_0/pattern_6 0.00921274 metacluster_0/pattern_10 0.0489249	Absent
Irf8	Pattern Name Modisco Significance metacluster_0/pattern_0 0.00897257 metacluster_0/pattern_5 4.52506e-06	Absent
Irf9	Pattern Name Modisco Significance metacluster_0/pattern_5 0.00044736099999999996	Absent
Cebpg	Pattern Name Modisco Significance metacluster_0/pattern_6 0.0581974	Absent
Rfx2	Pattern Name Modisco Significance metacluster_0/pattern_11 4.03622e-08	Absent

Unique Homer TFs: #2

TF Name	Modisco	Homer
Zbtb1	Absent	Pattern Name Homer Significance motif3.motif 0.033403699999999995
E2f7	Absent	Pattern Name Homer Significance motif3.motif 0.05022