In [1]:
# Parameters
data_name = "Erythroblast;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_45-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_45-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:50:19,215 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeErythroblasts
    Cell GroupOther Immune Cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1652405269010.20054333322870060110.161766706150.154144037410.3325
    Modelling Metadata
    MetricValue
    auPRC0.6192
    Calibrated Recall at 50% FDR0.185
    Number of Positive Examples in Test Data55205
    Number of Negative Examples in Test Data8015646
    Imbalance Ratio in Test Data0.0068
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #21
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5172 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 2544 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Klf3, Sp3, Sp1, E2f4, Klf6, Klf7, Klf4, Klf1,

Egr1, Klf8, Klf12, Egr2, Zbtb17, E2f1, Sp5, Klf5, Zfp281, Zfx, Zfp740,

Egr3
metacluster_1/pattern_2 # seqlets: 2075 SequenceContrib ScoresHyp_Contrib Scores
Gabpa, Fli1, Elk1, Elk4, Ets1, Erg, Elk3, Fev, Elf1, Etv5,

Etv4, Etv1, Etv6, Elf2, Ehf, Etv3, XP_911724.4, Elf5, Etv2, Elf4, Spi1,

Elf3, Spdef
metacluster_1/pattern_3 # seqlets: 2005 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_4 # seqlets: 1640 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Foxi1, Nfyc, Nfya, Pbx3
metacluster_1/pattern_5 # seqlets: 1191 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Rfx1, Zfp42, Wt1, Mxi1, Usf2
metacluster_1/pattern_6 # seqlets: 1031 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_7 # seqlets: 898 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Jdp2, Atf7, Atf2, Atf1, Atf3, Fosl2, Creb5, Crem, Fosl1,

Jun, Nfil3, Tef, Hlf, Srebf2, Creb3l2, Cebpb
metacluster_1/pattern_8 # seqlets: 889 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_9 # seqlets: 816 SequenceContrib ScoresHyp_Contrib Scores
Gata1, Tal1, Gata4, Gata5, Gata6, Gata2, Gata3
metacluster_1/pattern_10 # seqlets: 782 SequenceContrib ScoresHyp_Contrib Scores
Nfe2, Bach2, Nfe2l2, Bach1, Mafa, Mafk, Mafb, Mafg, Maff, Maf,

Fosb, Junb, Batf, Jund, Fos
metacluster_1/pattern_11 # seqlets: 647 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_12 # seqlets: 571 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Arntl, Tfeb, Tfec, Tfe3, Mitf, Clock, Bhlhe40, Arnt, Srebf1,

Mlx, Npas2, Tcfl5, Bhlhe41, Mycn, Myc, Nr1h4, Max
metacluster_1/pattern_13 # seqlets: 570 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_14 # seqlets: 567 SequenceContrib ScoresHyp_Contrib Scores
Sall4
metacluster_1/pattern_15 # seqlets: 464 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 398 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Irf7, Prdm1, Irf8, Stat1, Irf3, Stat2, Irf9, Irf4,

Spib, Batf3
metacluster_1/pattern_17 # seqlets: 83 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_18 # seqlets: 70 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib, Nfic, Zfp322a
metacluster_1/pattern_19 # seqlets: 61 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_20 # seqlets: 46 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #143
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_01.14386e-13
metacluster_1/pattern_133.1640700000000004e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_03.42107e-08
metacluster_1/pattern_70.051116800000000004
metacluster_1/pattern_130.00144704
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00272863
metacluster_1/pattern_110.012018299999999999
metacluster_1/pattern_140.00747358
metacluster_1/pattern_150.0031203000000000003
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_18.53938e-06
metacluster_1/pattern_58.48792e-05
metacluster_1/pattern_70.0157325
metacluster_1/pattern_110.00122027
metacluster_1/pattern_120.00121332
metacluster_1/pattern_140.0378043
metacluster_1/pattern_170.00378653
metacluster_1/pattern_200.018497
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_18.53938e-06
metacluster_1/pattern_50.043813099999999994
metacluster_1/pattern_110.00075463
metacluster_1/pattern_120.00994497
metacluster_1/pattern_140.00418917
metacluster_1/pattern_150.0234577
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_11.6421199999999998e-05
metacluster_1/pattern_50.000459035
metacluster_1/pattern_110.00122027
metacluster_1/pattern_120.00144906
metacluster_1/pattern_140.0336754
metacluster_1/pattern_170.00301412
metacluster_1/pattern_200.0524862
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000947355
metacluster_1/pattern_50.00021018599999999998
metacluster_1/pattern_110.00626199
metacluster_1/pattern_120.00375717
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000313278
metacluster_1/pattern_110.011967799999999999
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000470355
metacluster_1/pattern_110.008661499999999999
metacluster_1/pattern_140.00683624
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000947355
metacluster_1/pattern_110.000544951
metacluster_1/pattern_140.0336754
metacluster_1/pattern_150.00189865
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015972999999999998
metacluster_1/pattern_110.00568979
metacluster_1/pattern_140.00642204
metacluster_1/pattern_150.00114863
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0575192
metacluster_1/pattern_110.00270669
metacluster_1/pattern_140.00683624
metacluster_1/pattern_150.000512786
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0508357
metacluster_1/pattern_110.0295091
metacluster_1/pattern_140.0566717
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00143922
metacluster_1/pattern_110.00075463
metacluster_1/pattern_140.0154851
metacluster_1/pattern_150.000884193
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0161543
metacluster_1/pattern_110.00075463
metacluster_1/pattern_140.0313279
metacluster_1/pattern_150.00189865
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.040923900000000006
metacluster_1/pattern_50.0411541
metacluster_1/pattern_110.047843199999999995
metacluster_1/pattern_140.046435199999999996
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0115059
metacluster_1/pattern_50.0137196
metacluster_1/pattern_120.0426498
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0118542
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0205774
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0221466
metacluster_1/pattern_140.0154851
metacluster_1/pattern_150.024975999999999998
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0367805
metacluster_1/pattern_110.0114751
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0436433
metacluster_1/pattern_30.029632099999999998
metacluster_1/pattern_50.00180904
metacluster_1/pattern_70.0272031
metacluster_1/pattern_120.012994299999999999
metacluster_1/pattern_170.014416499999999999
metacluster_1/pattern_200.0217056
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_10.045426999999999995
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0508357
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00181184
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0028921
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00140481
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00188017
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00275149
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0028921
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00107754
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000399764
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000610843
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000758883
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00612704
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00196806
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.020094499999999998
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0188382
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0205425
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00392187
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00396198
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0337892
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00612704
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0126242
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0188382
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0514861
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_20.020094499999999998
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_33.83928e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_42.3095400000000002e-10
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_44.9049e-06
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_44.9049e-06
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_44.9049e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00015463399999999998
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.15581e-06
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.15581e-06
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00642362
metacluster_1/pattern_120.0102434
metacluster_1/pattern_176.8644799999999994e-09
metacluster_1/pattern_200.0004891359999999999
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00746375
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0270858
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0512065
metacluster_1/pattern_120.00253943
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.058292
metacluster_1/pattern_70.000422534
metacluster_1/pattern_120.013596
metacluster_1/pattern_170.0288161
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0302587
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0007860660000000001
metacluster_1/pattern_120.0270399
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00103931
metacluster_1/pattern_100.013498300000000001
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000322557
metacluster_1/pattern_120.0270399
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000576891
metacluster_1/pattern_120.03793819999999999
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0294545
metacluster_1/pattern_120.034850599999999995
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000643893
metacluster_1/pattern_100.00431329
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00208321
metacluster_1/pattern_100.00758765
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00208321
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00259352
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00596836
metacluster_1/pattern_100.00758765
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0294545
metacluster_1/pattern_100.00244214
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.015394299999999998
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0249312
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_70.039878500000000004
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.045248699999999996
metacluster_1/pattern_120.004940600000000001
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.045248699999999996
metacluster_1/pattern_120.022336099999999998
Cebpb
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0592125
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_81.3441399999999998e-22
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_89.32266e-22
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_82.1488099999999999e-13
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000589915
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_94.96281e-07
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00021865
Gata5
Pattern NameModiscoSignificance
metacluster_1/pattern_94.84705e-05
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_94.84705e-05
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00021865
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05420030000000001
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_108.234950000000001e-09
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_108.83733e-09
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_109.08513e-08
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_102.8131000000000002e-06
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00048351300000000003
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0009676210000000001
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00244214
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00231423
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00246156
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00290288
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00613107
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00698033
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0564226
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0564226
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_100.012127200000000001
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0394005
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00994497
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0012809000000000002
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00659658
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00584861
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0033542999999999997
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0006457619999999999
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00994497
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.042541699999999995
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00816779
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.034850599999999995
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00394609
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.011744200000000002
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.020334400000000002
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0327833
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0347107
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0394005
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0457837
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.04176130000000001
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_169.26156e-08
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00379734
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_162.3494000000000002e-05
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_163.53236e-05
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_168.83391e-05
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000141381
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000743463
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000811583
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_160.002669
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0174757
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0154792
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.046155400000000006
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00496573
metacluster_1/pattern_200.047926300000000005
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_171.92182e-08
metacluster_1/pattern_200.0419861
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00063704
metacluster_1/pattern_200.018497
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00375798
metacluster_1/pattern_200.00981944
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00931499
metacluster_1/pattern_200.00285078
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_185.2852799999999996e-05
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00115195
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0165267
Zfp322a
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0306466
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #73
TF NameModiscoHomer
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0508357
metacluster_1/pattern_110.0295091
metacluster_1/pattern_140.0566717
Pattern NameHomerSignificance
motif2.motif0.0310568
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000947355
metacluster_1/pattern_50.00021018599999999998
metacluster_1/pattern_110.00626199
metacluster_1/pattern_120.00375717
Pattern NameHomerSignificance
motif2.motif0.0192775
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_18.53938e-06
metacluster_1/pattern_50.043813099999999994
metacluster_1/pattern_110.00075463
metacluster_1/pattern_120.00994497
metacluster_1/pattern_140.00418917
metacluster_1/pattern_150.0234577
Pattern NameHomerSignificance
motif2.motif0.00451121
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0564226
Pattern NameHomerSignificance
motif19.motif0.0167354
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0575192
metacluster_1/pattern_110.00270669
metacluster_1/pattern_140.00683624
metacluster_1/pattern_150.000512786
Pattern NameHomerSignificance
motif2.motif0.0192775
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_82.1488099999999999e-13
Pattern NameHomerSignificance
motif5.motif7.27375e-05
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.020094499999999998
Pattern NameHomerSignificance
motif3.motif0.00299144
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000643893
metacluster_1/pattern_100.00431329
Pattern NameHomerSignificance
motif8.motif0.050685900000000006
motif19.motif0.00707673
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_03.42107e-08
metacluster_1/pattern_70.051116800000000004
metacluster_1/pattern_130.00144704
Pattern NameHomerSignificance
motif1.motif3.17068e-05
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0205774
Pattern NameHomerSignificance
motif2.motif0.0262863
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_108.234950000000001e-09
Pattern NameHomerSignificance
motif19.motif9.42994e-05
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000313278
metacluster_1/pattern_110.011967799999999999
Pattern NameHomerSignificance
motif2.motif0.0192083
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00612704
Pattern NameHomerSignificance
motif3.motif0.05310940000000001
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000758883
Pattern NameHomerSignificance
motif3.motif0.00232817
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_109.08513e-08
Pattern NameHomerSignificance
motif19.motif0.00036012699999999996
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00048351300000000003
Pattern NameHomerSignificance
motif19.motif0.00180477
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0205425
Pattern NameHomerSignificance
motif3.motif0.0177187
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_44.9049e-06
Pattern NameHomerSignificance
motif6.motif0.024562999999999998
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0294545
metacluster_1/pattern_100.00244214
Pattern NameHomerSignificance
motif19.motif0.00263912
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00613107
Pattern NameHomerSignificance
motif19.motif0.00881238
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_42.3095400000000002e-10
Pattern NameHomerSignificance
motif6.motif0.00137619
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_81.3441399999999998e-22
Pattern NameHomerSignificance
motif5.motif9.19249e-06
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0564226
Pattern NameHomerSignificance
motif19.motif0.05952230000000001
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00015463399999999998
Pattern NameHomerSignificance
motif6.motif0.024562999999999998
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000470355
metacluster_1/pattern_110.008661499999999999
metacluster_1/pattern_140.00683624
Pattern NameHomerSignificance
motif2.motif0.029653
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_11.6421199999999998e-05
metacluster_1/pattern_50.000459035
metacluster_1/pattern_110.00122027
metacluster_1/pattern_120.00144906
metacluster_1/pattern_140.0336754
metacluster_1/pattern_170.00301412
metacluster_1/pattern_200.0524862
Pattern NameHomerSignificance
motif2.motif0.00729767
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00188017
Pattern NameHomerSignificance
motif3.motif0.00317101
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015972999999999998
metacluster_1/pattern_110.00568979
metacluster_1/pattern_140.00642204
metacluster_1/pattern_150.00114863
Pattern NameHomerSignificance
motif2.motif0.0117463
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00698033
Pattern NameHomerSignificance
motif19.motif0.00881238
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0126242
Pattern NameHomerSignificance
motif3.motif0.00336755
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00103931
metacluster_1/pattern_100.013498300000000001
Pattern NameHomerSignificance
motif19.motif0.022239
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_108.83733e-09
Pattern NameHomerSignificance
motif19.motif1.4690399999999999e-06
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00143922
metacluster_1/pattern_110.00075463
metacluster_1/pattern_140.0154851
metacluster_1/pattern_150.000884193
Pattern NameHomerSignificance
motif2.motif0.00264885
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_20.020094499999999998
Pattern NameHomerSignificance
motif3.motif0.019949
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0188382
Pattern NameHomerSignificance
motif3.motif0.00426027
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_100.012127200000000001
Pattern NameHomerSignificance
motif19.motif0.023697299999999998
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0337892
Pattern NameHomerSignificance
motif3.motif0.00761036
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_33.83928e-07
Pattern NameHomerSignificance
motif7.motif0.000329401
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.15581e-06
Pattern NameHomerSignificance
motif12.motif0.014925999999999998
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_44.9049e-06
Pattern NameHomerSignificance
motif6.motif0.00185632
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000947355
metacluster_1/pattern_110.000544951
metacluster_1/pattern_140.0336754
metacluster_1/pattern_150.00189865
Pattern NameHomerSignificance
motif2.motif0.00264885
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0188382
Pattern NameHomerSignificance
motif3.motif0.053263
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00208321
metacluster_1/pattern_100.00758765
Pattern NameHomerSignificance
motif19.motif0.0204294
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_18.53938e-06
metacluster_1/pattern_58.48792e-05
metacluster_1/pattern_70.0157325
metacluster_1/pattern_110.00122027
metacluster_1/pattern_120.00121332
metacluster_1/pattern_140.0378043
metacluster_1/pattern_170.00378653
metacluster_1/pattern_200.018497
Pattern NameHomerSignificance
motif2.motif0.00980913
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.15581e-06
Pattern NameHomerSignificance
motif12.motif0.0020725
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0221466
metacluster_1/pattern_140.0154851
metacluster_1/pattern_150.024975999999999998
Pattern NameHomerSignificance
motif2.motif0.0259743
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0294545
metacluster_1/pattern_120.034850599999999995
Pattern NameHomerSignificance
motif8.motif0.050685900000000006
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0161543
metacluster_1/pattern_110.00075463
metacluster_1/pattern_140.0313279
metacluster_1/pattern_150.00189865
Pattern NameHomerSignificance
motif2.motif0.029653
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00140481
Pattern NameHomerSignificance
motif3.motif0.0028279
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_44.9049e-06
Pattern NameHomerSignificance
motif6.motif0.00311267
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0007860660000000001
metacluster_1/pattern_120.0270399
Pattern NameHomerSignificance
motif8.motif0.00581664
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00246156
Pattern NameHomerSignificance
motif19.motif0.012829499999999999
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00612704
Pattern NameHomerSignificance
motif3.motif0.00495915
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00181184
Pattern NameHomerSignificance
motif3.motif0.0028279
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00107754
Pattern NameHomerSignificance
motif3.motif0.0028279
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00272863
metacluster_1/pattern_110.012018299999999999
metacluster_1/pattern_140.00747358
metacluster_1/pattern_150.0031203000000000003
Pattern NameHomerSignificance
motif2.motif0.0192775
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_01.14386e-13
metacluster_1/pattern_133.1640700000000004e-05
Pattern NameHomerSignificance
motif1.motif5.04779e-07
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00392187
Pattern NameHomerSignificance
motif3.motif0.00390927
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0514861
Pattern NameHomerSignificance
motif3.motif0.0346664
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00396198
Pattern NameHomerSignificance
motif3.motif0.00390927
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00196806
Pattern NameHomerSignificance
motif3.motif0.0028279
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00231423
Pattern NameHomerSignificance
motif19.motif0.00881238
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00275149
Pattern NameHomerSignificance
motif3.motif0.00413051
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000399764
Pattern NameHomerSignificance
motif3.motif0.0028279
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_89.32266e-22
Pattern NameHomerSignificance
motif5.motif1.17652e-06
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0009676210000000001
Pattern NameHomerSignificance
motif19.motif0.00450059
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00244214
Pattern NameHomerSignificance
motif19.motif0.012069400000000001
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0028921
Pattern NameHomerSignificance
motif3.motif0.00343897
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_102.8131000000000002e-06
Pattern NameHomerSignificance
motif19.motif9.42994e-05
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0028921
Pattern NameHomerSignificance
motif3.motif0.00343897
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000610843
Pattern NameHomerSignificance
motif3.motif0.00232817
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00596836
metacluster_1/pattern_100.00758765
Pattern NameHomerSignificance
motif19.motif0.0176856
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00290288
Pattern NameHomerSignificance
motif19.motif0.017098500000000003
Unique TF-MoDISco TFs: #70
TF NameModiscoHomer
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.040923900000000006
metacluster_1/pattern_50.0411541
metacluster_1/pattern_110.047843199999999995
metacluster_1/pattern_140.046435199999999996
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00584861
Absent
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0394005
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000576891
metacluster_1/pattern_120.03793819999999999
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0457837
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0118542
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00746375
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.04176130000000001
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00379734
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_185.2852799999999996e-05
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.011744200000000002
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00816779
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0512065
metacluster_1/pattern_120.00253943
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0033542999999999997
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0367805
metacluster_1/pattern_110.0114751
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.020334400000000002
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_70.015394299999999998
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000743463
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0115059
metacluster_1/pattern_50.0137196
metacluster_1/pattern_120.0426498
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_162.3494000000000002e-05
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00642362
metacluster_1/pattern_120.0102434
metacluster_1/pattern_176.8644799999999994e-09
metacluster_1/pattern_200.0004891359999999999
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.034850599999999995
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0436433
metacluster_1/pattern_30.029632099999999998
metacluster_1/pattern_50.00180904
metacluster_1/pattern_70.0272031
metacluster_1/pattern_120.012994299999999999
metacluster_1/pattern_170.014416499999999999
metacluster_1/pattern_200.0217056
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_168.83391e-05
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0249312
Absent
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_94.84705e-05
Absent
Gata5
Pattern NameModiscoSignificance
metacluster_1/pattern_94.84705e-05
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0006457619999999999
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0508357
Absent
Cebpb
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0592125
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000589915
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000141381
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00375798
metacluster_1/pattern_200.00981944
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_169.26156e-08
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0347107
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00994497
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_171.92182e-08
metacluster_1/pattern_200.0419861
Absent
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_94.96281e-07
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.045248699999999996
metacluster_1/pattern_120.004940600000000001
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_180.00115195
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_163.53236e-05
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00931499
metacluster_1/pattern_200.00285078
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_70.039878500000000004
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00259352
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00063704
metacluster_1/pattern_200.018497
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_70.045248699999999996
metacluster_1/pattern_120.022336099999999998
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0394005
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0174757
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00994497
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_10.045426999999999995
Absent
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00021865
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0012809000000000002
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0165267
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00659658
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0302587
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000811583
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00394609
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0270858
Absent
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0154792
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.042541699999999995
Absent
Zfp322a
Pattern NameModiscoSignificance
metacluster_1/pattern_180.0306466
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.058292
metacluster_1/pattern_70.000422534
metacluster_1/pattern_120.013596
metacluster_1/pattern_170.0288161
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.046155400000000006
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_160.002669
Absent
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05420030000000001
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_70.00208321
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0327833
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00496573
metacluster_1/pattern_200.047926300000000005
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_70.000322557
metacluster_1/pattern_120.0270399
Absent
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00021865
Absent
Unique Homer TFs: #3
TF NameModiscoHomer
Zic3Absent
Pattern NameHomerSignificance
motif1.motif0.0229848
Zic2Absent
Pattern NameHomerSignificance
motif1.motif0.0229848
Zbtb1Absent
Pattern NameHomerSignificance
motif2.motif0.0309465