In [1]:
# Parameters
data_name = "Tfh_LCMV;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_23-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_23-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:45:13,832 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeTfh from infected with LCMV
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1967797287710.96153924622574282460.189456784320.1448133349410.3399
    Modelling Metadata
    MetricValue
    auPRC0.5843
    Calibrated Recall at 50% FDR0.217
    Number of Positive Examples in Test Data80787
    Number of Negative Examples in Test Data7990064
    Imbalance Ratio in Test Data0.01
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #24
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5764 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4729 SequenceContrib ScoresHyp_Contrib Scores
Gabpa, Ets1, Etv2, Erg, Sp2, Fli1, Sp1, Elk1, Spi1, Elk4,

Sp3, Maz, Etv4, Elf1, Mxi1, Sp5, Etv6, Elf3, Ehf, Zbtb17, Wt1,

Elk3, Etv1, Etv5, Rela, Klf15, Klf3, Fev, Klf6, Usf2, Etv3, XP_911724.4,

Gata1, Sp4, Spib, Bcl6, Elf2, Elf5, Elf4, Zfx, Irf3, Prdm1, Tal1,

Zfp281, Taf1, Ptf1a, Myc, Zfp740, Nr1h4, Egr1
metacluster_1/pattern_2 # seqlets: 3923 SequenceContrib ScoresHyp_Contrib Scores
Klf4, Klf5, E2f4, Klf7, Klf8, Klf12, Egr2, Klf1, E2f1, Sall4,

Egr3, Srebf2
metacluster_1/pattern_3 # seqlets: 1565 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_4 # seqlets: 1463 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Irf7, Irf8, Stat1, Stat2, Batf3, Irf4, Irf9
metacluster_1/pattern_5 # seqlets: 1424 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_6 # seqlets: 873 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_7 # seqlets: 691 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Zfp42, Rfx1
metacluster_1/pattern_8 # seqlets: 691 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf2, Atf1, Atf7, Crem, Jdp2, Creb5, Atf3, Fosl2, Jun,

Nfil3, Rxrb, Fosl1, Hlf
metacluster_1/pattern_9 # seqlets: 625 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Cbfb, Runx3
metacluster_1/pattern_10 # seqlets: 625 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_11 # seqlets: 616 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx6, Rfx7
metacluster_1/pattern_12 # seqlets: 479 SequenceContrib ScoresHyp_Contrib Scores
Fos, Batf, Jund, Junb, Fosb, Bach2, Nfe2l2, Nfe2, Bach1, Mafk,

Mafa, Mafb, Mafg, Maff, Maf
metacluster_1/pattern_13 # seqlets: 478 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfe3, Tfeb, Arntl, Tfec, Mitf, Srebf1, Bhlhe40, Clock, Arnt,

Mlx, Npas2, Mycn, Tcfl5, Max, Creb3l2, Bhlhe41, Xbp1, Mlxip
metacluster_1/pattern_14 # seqlets: 263 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2, Pou2f1
metacluster_1/pattern_15 # seqlets: 226 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Relb, Rel
metacluster_1/pattern_16 # seqlets: 186 SequenceContrib ScoresHyp_Contrib Scores
Tcf7l2, Lef1, Tcf3, Tcf7l1, Tcf7, Pbx1
metacluster_1/pattern_17 # seqlets: 139 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_18 # seqlets: 118 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_19 # seqlets: 101 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_20 # seqlets: 86 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_21 # seqlets: 83 SequenceContrib ScoresHyp_Contrib Scores
Nfib, Nfia, Nfic
metacluster_1/pattern_22 # seqlets: 67 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_23 # seqlets: 39 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #158
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_01.0130899999999999e-14
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_01.10156e-07
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00468124
metacluster_1/pattern_190.0353125
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00311718
metacluster_1/pattern_100.0517783
metacluster_1/pattern_190.017755700000000003
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_11.8169200000000002e-05
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00264617
metacluster_1/pattern_190.0461889
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_17.789300000000001e-05
metacluster_1/pattern_24.26942e-09
metacluster_1/pattern_70.000237243
metacluster_1/pattern_170.000673425
metacluster_1/pattern_198.821190000000001e-05
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0030791
metacluster_1/pattern_190.017755700000000003
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_18.427659999999999e-05
metacluster_1/pattern_20.00035173699999999997
metacluster_1/pattern_70.000776871
metacluster_1/pattern_170.00401952
metacluster_1/pattern_190.017755700000000003
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00365328
metacluster_1/pattern_190.0516016
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00113292
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00416526
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00030801099999999996
metacluster_1/pattern_21.1049799999999999e-08
metacluster_1/pattern_70.00203885
metacluster_1/pattern_170.00108875
metacluster_1/pattern_190.00642281
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0003085
metacluster_1/pattern_20.00886238
metacluster_1/pattern_190.0500481
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00311718
metacluster_1/pattern_190.0279714
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000592174
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0006628669999999999
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000834169
metacluster_1/pattern_20.0006559589999999999
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0567911
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.020840900000000002
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00211384
metacluster_1/pattern_20.00126678
metacluster_1/pattern_70.030104500000000003
metacluster_1/pattern_190.0279714
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00244367
metacluster_1/pattern_20.0046172
metacluster_1/pattern_190.0455517
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0030791
metacluster_1/pattern_190.0286285
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00365328
metacluster_1/pattern_190.021631400000000002
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00416526
metacluster_1/pattern_190.0218416
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00453941
metacluster_1/pattern_150.00019051700000000002
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00453941
metacluster_1/pattern_20.0414931
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00556737
metacluster_1/pattern_21.33695e-07
metacluster_1/pattern_190.00642281
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00556737
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00574438
metacluster_1/pattern_20.000275374
metacluster_1/pattern_190.0183
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
metacluster_1/pattern_84.47517e-05
metacluster_1/pattern_130.00442487
metacluster_1/pattern_170.026661900000000002
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00713785
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00785671
metacluster_1/pattern_20.000698833
metacluster_1/pattern_190.0461889
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00960607
metacluster_1/pattern_40.00908235
Bcl6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013929599999999999
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0139624
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.03490580000000001
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016052700000000003
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0170856
metacluster_1/pattern_50.05157949999999999
metacluster_1/pattern_70.00451024
metacluster_1/pattern_170.00285326
metacluster_1/pattern_190.0183
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0182362
metacluster_1/pattern_40.00953116
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.020296400000000003
metacluster_1/pattern_40.00251178
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.023814500000000002
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.030248900000000002
metacluster_1/pattern_20.0046172
metacluster_1/pattern_190.0500481
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0368425
metacluster_1/pattern_74.5531699999999995e-06
Ptf1a
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0458839
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_10.049251300000000005
metacluster_1/pattern_130.0238746
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0497003
metacluster_1/pattern_20.0375783
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.055819900000000006
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0581563
metacluster_1/pattern_20.0421599
metacluster_1/pattern_190.0516016
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000450965
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00035173699999999997
metacluster_1/pattern_190.0389935
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00036426599999999997
metacluster_1/pattern_190.00206739
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000392628
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000627614
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0006559589999999999
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0288062
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.04843
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.015840200000000002
metacluster_1/pattern_190.0516016
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.022333000000000002
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0243576
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0306288
metacluster_1/pattern_130.00592386
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_37.56919e-15
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_35.80422e-11
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_39.0455e-09
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_33.32371e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_33.32371e-06
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.95989e-13
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00111255
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_43.5037100000000004e-05
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000164418
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0007036439999999999
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00111255
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00111255
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00908235
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00229512
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.39265e-07
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_61.02531e-23
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_61.22148e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_66.210000000000001e-13
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_79.0524e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0104796
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0310116
metacluster_1/pattern_117.24268e-11
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00197091
metacluster_1/pattern_130.0285812
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00196652
metacluster_1/pattern_130.0585719
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0184139
metacluster_1/pattern_130.024533000000000003
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000545473
metacluster_1/pattern_130.039537699999999995
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0090162
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00159852
metacluster_1/pattern_120.000188215
metacluster_1/pattern_130.05362190000000001
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0018135999999999998
metacluster_1/pattern_130.04989880000000001
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0090162
metacluster_1/pattern_120.000188215
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.033137099999999996
metacluster_1/pattern_121.4695699999999999e-05
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.033882300000000004
metacluster_1/pattern_121.3808699999999999e-05
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0435014
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0459439
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0500559
metacluster_1/pattern_120.018090000000000002
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.051540499999999996
metacluster_1/pattern_130.0285812
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00925274
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0102417
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0102417
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0102417
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000978462
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0451202
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_113.036e-05
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000332271
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000343945
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_121.3808699999999999e-05
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.019750099999999996
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00820987
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.018090000000000002
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000188215
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000908975
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00163468
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00146455
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00157929
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_120.012243299999999999
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00759004
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0224118
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_120.028355
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0376026
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.050977800000000004
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.018550599999999997
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000678555
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000189127
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00548519
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000688551
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00039570699999999997
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.029619200000000002
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0160526
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0218713
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0438897
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00700026
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00354677
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0118957
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0134334
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0155566
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0332411
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0262032
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0475693
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0585719
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00372249
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0172666
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_151.77795e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_151.77795e-05
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0007989560000000001
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00497357
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00883049
metacluster_1/pattern_180.000225364
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00529201
metacluster_1/pattern_189.40481e-07
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00779234
metacluster_1/pattern_180.000305744
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0410156
metacluster_1/pattern_180.000225364
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.05855930000000001
metacluster_1/pattern_180.00513962
Pbx1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.05855930000000001
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000105927
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_210.000166617
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_210.000606338
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_210.0441246
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #53
TF NameModiscoHomer
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0006559589999999999
Pattern NameHomerSignificance
motif3.motif0.0141972
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_39.0455e-09
Pattern NameHomerSignificance
motif7.motif3.12183e-05
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00264617
metacluster_1/pattern_190.0461889
Pattern NameHomerSignificance
motif2.motif5.75914e-06
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_35.80422e-11
Pattern NameHomerSignificance
motif7.motif3.85896e-05
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00365328
metacluster_1/pattern_190.021631400000000002
Pattern NameHomerSignificance
motif2.motif2.68276e-07
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00311718
metacluster_1/pattern_190.0279714
Pattern NameHomerSignificance
motif2.motif0.00510273
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000592174
Pattern NameHomerSignificance
motif2.motif0.00619822
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00036426599999999997
metacluster_1/pattern_190.00206739
Pattern NameHomerSignificance
motif3.motif0.000778492
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_18.427659999999999e-05
metacluster_1/pattern_20.00035173699999999997
metacluster_1/pattern_70.000776871
metacluster_1/pattern_170.00401952
metacluster_1/pattern_190.017755700000000003
Pattern NameHomerSignificance
motif3.motif0.00535454
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0030791
metacluster_1/pattern_190.0286285
Pattern NameHomerSignificance
motif2.motif0.000407058
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00556737
Pattern NameHomerSignificance
motif2.motif0.00334155
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00030801099999999996
metacluster_1/pattern_21.1049799999999999e-08
metacluster_1/pattern_70.00203885
metacluster_1/pattern_170.00108875
metacluster_1/pattern_190.00642281
Pattern NameHomerSignificance
motif3.motif5.403479999999999e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_01.10156e-07
Pattern NameHomerSignificance
motif1.motif0.000574497
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_11.8169200000000002e-05
Pattern NameHomerSignificance
motif2.motif0.00126214
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00311718
metacluster_1/pattern_100.0517783
metacluster_1/pattern_190.017755700000000003
Pattern NameHomerSignificance
motif2.motif1.6153699999999997e-05
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00416526
Pattern NameHomerSignificance
motif2.motif5.74355e-06
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00365328
metacluster_1/pattern_190.0516016
Pattern NameHomerSignificance
motif2.motif0.00028124599999999997
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0139624
Pattern NameHomerSignificance
motif2.motif0.0208051
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.016052700000000003
Pattern NameHomerSignificance
motif2.motif0.00334155
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000627614
Pattern NameHomerSignificance
motif3.motif0.0009958039999999999
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
Pattern NameHomerSignificance
motif2.motif0.000111901
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00468124
metacluster_1/pattern_190.0353125
Pattern NameHomerSignificance
motif2.motif0.00339796
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00416526
metacluster_1/pattern_190.0218416
Pattern NameHomerSignificance
motif2.motif3.0469700000000002e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0104796
Pattern NameHomerSignificance
motif13.motif0.00601071
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.020840900000000002
Pattern NameHomerSignificance
motif2.motif0.00345771
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000450965
Pattern NameHomerSignificance
motif3.motif0.0575875
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00211384
metacluster_1/pattern_20.00126678
metacluster_1/pattern_70.030104500000000003
metacluster_1/pattern_190.0279714
Pattern NameHomerSignificance
motif3.motif0.0555922
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00785671
metacluster_1/pattern_20.000698833
metacluster_1/pattern_190.0461889
Pattern NameHomerSignificance
motif3.motif0.019938900000000002
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_61.02531e-23
Pattern NameHomerSignificance
motif5.motif0.00255337
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00556737
metacluster_1/pattern_21.33695e-07
metacluster_1/pattern_190.00642281
Pattern NameHomerSignificance
motif3.motif5.403479999999999e-05
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.04843
Pattern NameHomerSignificance
motif3.motif0.040843800000000006
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0567911
Pattern NameHomerSignificance
motif2.motif0.0446475
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000392628
Pattern NameHomerSignificance
motif3.motif0.0006084630000000001
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.39265e-07
Pattern NameHomerSignificance
motif10.motif1.7716599999999999e-06
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0581563
metacluster_1/pattern_20.0421599
metacluster_1/pattern_190.0516016
Pattern NameHomerSignificance
motif3.motif0.0149656
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_37.56919e-15
Pattern NameHomerSignificance
motif7.motif8.15789e-07
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_79.0524e-06
Pattern NameHomerSignificance
motif13.motif0.00018559299999999998
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_01.0130899999999999e-14
Pattern NameHomerSignificance
motif1.motif1.95064e-05
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00035173699999999997
metacluster_1/pattern_190.0389935
Pattern NameHomerSignificance
motif3.motif0.0158282
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
Pattern NameHomerSignificance
motif2.motif0.010469299999999999
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_17.789300000000001e-05
metacluster_1/pattern_24.26942e-09
metacluster_1/pattern_70.000237243
metacluster_1/pattern_170.000673425
metacluster_1/pattern_198.821190000000001e-05
Pattern NameHomerSignificance
motif3.motif2.28411e-05
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00574438
metacluster_1/pattern_20.000275374
metacluster_1/pattern_190.0183
Pattern NameHomerSignificance
motif3.motif0.0006084630000000001
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00883049
metacluster_1/pattern_180.000225364
Pattern NameHomerSignificance
motif16.motif0.0180669
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0030791
metacluster_1/pattern_190.017755700000000003
Pattern NameHomerSignificance
motif2.motif0.000100845
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.015840200000000002
metacluster_1/pattern_190.0516016
Pattern NameHomerSignificance
motif3.motif0.05743380000000001
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_66.210000000000001e-13
Pattern NameHomerSignificance
motif5.motif0.00207343
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0368425
metacluster_1/pattern_74.5531699999999995e-06
Pattern NameHomerSignificance
motif13.motif1.91782e-05
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.03490580000000001
Pattern NameHomerSignificance
motif2.motif0.0446475
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
Pattern NameHomerSignificance
motif2.motif0.000100845
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0288062
Pattern NameHomerSignificance
motif3.motif0.05743380000000001
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_33.32371e-06
Pattern NameHomerSignificance
motif7.motif0.00191927
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_61.22148e-21
Pattern NameHomerSignificance
motif5.motif0.00356744
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_33.32371e-06
Pattern NameHomerSignificance
motif7.motif0.00257241
Unique TF-MoDISco TFs: #105
TF NameModiscoHomer
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00111255
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0243576
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_113.036e-05
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0134334
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0182362
metacluster_1/pattern_40.00953116
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000978462
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00670534
metacluster_1/pattern_84.47517e-05
metacluster_1/pattern_130.00442487
metacluster_1/pattern_170.026661900000000002
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00197091
metacluster_1/pattern_130.0285812
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00146455
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0224118
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0438897
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0170856
metacluster_1/pattern_50.05157949999999999
metacluster_1/pattern_70.00451024
metacluster_1/pattern_170.00285326
metacluster_1/pattern_190.0183
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00548519
Absent
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00372249
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_120.028355
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.029619200000000002
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.018090000000000002
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0262032
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.022333000000000002
Absent
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0172666
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000188215
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00700026
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000343945
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.018550599999999997
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0160526
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0332411
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0306288
metacluster_1/pattern_130.00592386
Absent
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00529201
metacluster_1/pattern_189.40481e-07
Absent
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00960607
metacluster_1/pattern_40.00908235
Absent
Bcl6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013929599999999999
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00713785
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0451202
Absent
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_151.77795e-05
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.051540499999999996
metacluster_1/pattern_130.0285812
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0376026
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000164418
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00925274
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.033137099999999996
metacluster_1/pattern_121.4695699999999999e-05
Absent
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00453941
metacluster_1/pattern_150.00019051700000000002
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000908975
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.050977800000000004
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0475693
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0118957
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0006628669999999999
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.019750099999999996
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000834169
metacluster_1/pattern_20.0006559589999999999
Absent
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.05855930000000001
metacluster_1/pattern_180.00513962
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0102417
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00354677
Absent
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.95989e-13
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00163468
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0102417
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00453941
metacluster_1/pattern_20.0414931
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000105927
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0435014
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00111255
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00196652
metacluster_1/pattern_130.0585719
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000678555
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0184139
metacluster_1/pattern_130.024533000000000003
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00111255
Absent
Pbx1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.05855930000000001
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0090162
metacluster_1/pattern_120.000188215
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00497357
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_10.049251300000000005
metacluster_1/pattern_130.0238746
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00159852
metacluster_1/pattern_120.000188215
metacluster_1/pattern_130.05362190000000001
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00820987
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00244367
metacluster_1/pattern_20.0046172
metacluster_1/pattern_190.0455517
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0155566
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_120.012243299999999999
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0500559
metacluster_1/pattern_120.018090000000000002
Absent
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00113292
Absent
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0410156
metacluster_1/pattern_180.000225364
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0007036439999999999
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0018135999999999998
metacluster_1/pattern_130.04989880000000001
Absent
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.055819900000000006
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0003085
metacluster_1/pattern_20.00886238
metacluster_1/pattern_190.0500481
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0090162
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000189127
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.020296400000000003
metacluster_1/pattern_40.00251178
Absent
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_151.77795e-05
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00908235
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_210.000606338
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_210.0441246
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0497003
metacluster_1/pattern_20.0375783
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000545473
metacluster_1/pattern_130.039537699999999995
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000332271
Absent
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00779234
metacluster_1/pattern_180.000305744
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.033882300000000004
metacluster_1/pattern_121.3808699999999999e-05
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_10.030248900000000002
metacluster_1/pattern_20.0046172
metacluster_1/pattern_190.0500481
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_43.5037100000000004e-05
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0102417
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0218713
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_121.3808699999999999e-05
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000688551
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0585719
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_210.000166617
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00157929
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_70.0310116
metacluster_1/pattern_117.24268e-11
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00039570699999999997
Absent
Ptf1a
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0458839
Absent
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00229512
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00759004
Absent
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.023814500000000002
Absent
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0007989560000000001
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0459439
Absent
Unique Homer TFs: #5
TF NameModiscoHomer
SpicAbsent
Pattern NameHomerSignificance
motif2.motif0.050237199999999996
Irf6Absent
Pattern NameHomerSignificance
motif2.motif0.026092400000000005
SpdefAbsent
Pattern NameHomerSignificance
motif2.motif0.0541481
Zbtb1Absent
Pattern NameHomerSignificance
motif3.motif0.040843800000000006
E2f7Absent
Pattern NameHomerSignificance
motif3.motif0.0479245