In [1]:
# Parameters
data_name = "SHRT_TRM_HSC;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_76-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_76-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:57:54,134 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeShort Term HSC
    Cell GroupOther Immune Cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep11330309693910.22352003678637179140.185735393820.176873523650.3673
    rep21330309693917.69452515135963518000.252747520930.189188874090.3536
    Modelling Metadata
    MetricValue
    auPRC0.6075
    Calibrated Recall at 50% FDR0.195
    Number of Positive Examples in Test Data112530
    Number of Negative Examples in Test Data7958321
    Imbalance Ratio in Test Data0.0139
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #18
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 3960 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 3418 SequenceContrib ScoresHyp_Contrib Scores
Spib, Spi1, Spic, Irf8, Irf4, Etv2, Etv6, Etv4, Elf3, Ets1,

Etv3, Ehf, Gabpa, Elk1, Erg, XP_911724.4, Fli1, Elf4, Irf3, Prdm1, Elf2,

Elk4, Elk3, Elf5, Etv1, Irf2, Elf1, Etv5, Irf1
metacluster_1/pattern_2 # seqlets: 3079 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp4, Sp3, Klf3, Sp1, E2f4, Klf6, Klf7, Klf4, Klf8,

Klf1, Klf12, Egr1, Zbtb17, Egr2, E2f1, Sp5, Klf5, Zfp281, Zfx, Zfp740,

Zbtb1, Egr3
metacluster_1/pattern_3 # seqlets: 1798 SequenceContrib ScoresHyp_Contrib Scores
Fev, Spdef, Mbd2, E2f3
metacluster_1/pattern_4 # seqlets: 1511 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf1, Tfe3, Jdp2, Tfec, Srebf1, Creb5, Usf1, Tfeb, Atf7,

Mitf, Arntl, Crem, Atf2, Mlx, Bhlhe40, Xbp1, Usf2, Clock, Srebf2, Rxrb,

Atf3, Creb3l2, Tef, Npas2, Nfil3, Jun, Dbp, Arnt, Hlf
metacluster_1/pattern_5 # seqlets: 1360 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_6 # seqlets: 1134 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_7 # seqlets: 1091 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_8 # seqlets: 805 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_9 # seqlets: 782 SequenceContrib ScoresHyp_Contrib Scores
Stat1, Irf7, Stat2, Irf9
metacluster_1/pattern_10 # seqlets: 745 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Rfx1, Zfp42, Mxi1
metacluster_1/pattern_11 # seqlets: 720 SequenceContrib ScoresHyp_Contrib Scores
Nfe2, Bach2, Nfe2l2, Bach1, Mafk, Mafa, Mafb, Mafg, Maff, Maf,

Fosb, Fosl2, Junb, Batf, Fosl1, Jund, Fos
metacluster_1/pattern_12 # seqlets: 701 SequenceContrib ScoresHyp_Contrib Scores
Stat4
metacluster_1/pattern_13 # seqlets: 482 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_1/pattern_14 # seqlets: 450 SequenceContrib ScoresHyp_Contrib Scores
Gata1, Gata4, Tal1, Gata6, Gata2, Gata5, Gata3
metacluster_1/pattern_15 # seqlets: 378 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 360 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_17 # seqlets: 347 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib, Nfic
Click here for Motifs by TF-MoDISco: #144
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_06.477230000000001e-16
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_04.3259099999999996e-08
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_12.0291099999999996e-06
metacluster_1/pattern_30.035829400000000004
metacluster_1/pattern_90.0316991
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00320441
metacluster_1/pattern_30.045173000000000005
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00320441
metacluster_1/pattern_30.058041999999999996
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00023936700000000001
metacluster_1/pattern_30.042508
metacluster_1/pattern_95.78161e-06
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000271747
metacluster_1/pattern_90.0160118
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00351255
metacluster_1/pattern_30.0005281169999999999
metacluster_1/pattern_120.00572388
metacluster_1/pattern_150.042996
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.045173000000000005
metacluster_1/pattern_120.037615800000000005
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037038800000000004
metacluster_1/pattern_30.010757
metacluster_1/pattern_120.0570462
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.057924300000000005
metacluster_1/pattern_30.035829400000000004
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000158026
metacluster_1/pattern_120.0332192
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000520328
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037406199999999994
metacluster_1/pattern_30.019065099999999998
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0487976
metacluster_1/pattern_30.0008784960000000001
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000232366
metacluster_1/pattern_120.0517597
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0227051
metacluster_1/pattern_30.000150983
metacluster_1/pattern_120.00848616
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000617198
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.014201599999999998
metacluster_1/pattern_30.000158026
metacluster_1/pattern_120.0517597
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0144458
metacluster_1/pattern_30.00841675
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015844999999999998
metacluster_1/pattern_90.00171505
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0180845
metacluster_1/pattern_30.058823900000000005
metacluster_1/pattern_98.11025e-05
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.020206000000000002
metacluster_1/pattern_30.058823900000000005
metacluster_1/pattern_120.0371455
metacluster_1/pattern_150.0385944
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0227051
metacluster_1/pattern_37.28841e-05
metacluster_1/pattern_120.037615800000000005
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0227051
metacluster_1/pattern_30.0005653359999999999
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037038800000000004
metacluster_1/pattern_30.047445999999999995
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037406199999999994
metacluster_1/pattern_30.00012206100000000001
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037038800000000004
metacluster_1/pattern_90.0013725999999999999
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0371184
metacluster_1/pattern_37.28841e-05
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0393653
metacluster_1/pattern_30.000293423
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0393653
metacluster_1/pattern_95.37258e-07
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_22.38333e-06
metacluster_1/pattern_100.00010458700000000001
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00152656
metacluster_1/pattern_100.0542884
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.816260000000001e-06
metacluster_1/pattern_100.00212318
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.15752e-05
metacluster_1/pattern_100.0542884
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000460676
metacluster_1/pattern_100.00203824
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000486253
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0005868140000000001
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000723097
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.014925999999999998
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00113501
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0483499
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.015903
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.044651800000000005
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00498363
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0466639
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.016460699999999998
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0196387
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0207058
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0213741
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0340026
metacluster_1/pattern_100.00203824
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0483499
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.05436030000000001
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.058797300000000004
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0005281169999999999
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_30.031144400000000003
Mbd2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.047445999999999995
E2f3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.058823900000000005
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00813025
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.018258
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0157519
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.013644299999999998
metacluster_1/pattern_110.009910700000000001
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0157519
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0301839
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00813025
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.011483499999999999
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_40.011483499999999999
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0123479
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_40.041509500000000005
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0140929
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_40.041509500000000005
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0226179
metacluster_1/pattern_100.0554725
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_40.011284899999999999
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0129708
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0157519
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.054860400000000004
metacluster_1/pattern_110.00364813
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0254488
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_40.026337
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0318443
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0340411
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_40.041509500000000005
metacluster_1/pattern_110.00210276
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_40.04795580000000001
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_40.054860400000000004
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0584358
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.07462e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_66.69998e-15
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_61.49607e-11
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_65.468730000000001e-10
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.1126299999999996e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_63.1126299999999996e-06
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000127633
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00921048
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000720837
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00252452
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0269599
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_95.78161e-06
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_92.20767e-05
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000966093
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00470541
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_106.738450000000001e-06
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_106.738450000000001e-06
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00203824
metacluster_1/pattern_161.62241e-09
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00955272
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.031051
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_118.0175e-08
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_111.00468e-07
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_111.00468e-07
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_111.60174e-05
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00112028
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000765963
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00210276
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00210276
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00245828
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0029006
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00444958
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00745151
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00558201
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.052887800000000006
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00745151
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_110.059112
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_110.009910700000000001
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0517597
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_134.90682e-18
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_135.5257900000000005e-18
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_131.42658e-12
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000138805
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0034856
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_146.84659e-05
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000242158
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00011075600000000001
Gata5
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000189291
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.013833700000000003
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00185956
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_164.23145e-08
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00011439600000000001
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000837598
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00166926
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_175.8959199999999994e-06
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_171.94056e-05
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00196197
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #62
TF NameModiscoHomer
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_04.3259099999999996e-08
Pattern NameHomerSignificance
motif1.motif0.000956114
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037038800000000004
metacluster_1/pattern_30.047445999999999995
Pattern NameHomerSignificance
motif2.motif0.0184847
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.014925999999999998
Pattern NameHomerSignificance
motif3.motif0.00180632
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0393653
metacluster_1/pattern_30.000293423
Pattern NameHomerSignificance
motif2.motif0.00036301199999999996
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_30.031144400000000003
Pattern NameHomerSignificance
motif2.motif0.010581299999999998
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037406199999999994
metacluster_1/pattern_30.00012206100000000001
Pattern NameHomerSignificance
motif2.motif0.00038010699999999997
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037038800000000004
metacluster_1/pattern_30.010757
metacluster_1/pattern_120.0570462
Pattern NameHomerSignificance
motif2.motif0.00245254
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_12.0291099999999996e-06
metacluster_1/pattern_30.035829400000000004
metacluster_1/pattern_90.0316991
Pattern NameHomerSignificance
motif2.motif0.000222697
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000723097
Pattern NameHomerSignificance
motif3.motif0.00131554
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0227051
metacluster_1/pattern_30.000150983
metacluster_1/pattern_120.00848616
Pattern NameHomerSignificance
motif2.motif0.00138052
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00320441
metacluster_1/pattern_30.058041999999999996
Pattern NameHomerSignificance
motif2.motif0.00030523299999999997
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_22.38333e-06
metacluster_1/pattern_100.00010458700000000001
Pattern NameHomerSignificance
motif3.motif0.00067764
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00498363
Pattern NameHomerSignificance
motif3.motif0.0442495
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0483499
Pattern NameHomerSignificance
motif3.motif0.00549814
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_65.468730000000001e-10
Pattern NameHomerSignificance
motif11.motif0.000911311
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_106.738450000000001e-06
Pattern NameHomerSignificance
motif14.motif7.69929e-05
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000232366
metacluster_1/pattern_120.0517597
Pattern NameHomerSignificance
motif2.motif0.00448132
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_134.90682e-18
Pattern NameHomerSignificance
motif5.motif3.11977e-06
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_131.42658e-12
Pattern NameHomerSignificance
motif5.motif9.76429e-05
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_66.69998e-15
Pattern NameHomerSignificance
motif11.motif0.00027938400000000003
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0227051
metacluster_1/pattern_37.28841e-05
metacluster_1/pattern_120.037615800000000005
Pattern NameHomerSignificance
motif2.motif0.00245254
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015844999999999998
metacluster_1/pattern_90.00171505
Pattern NameHomerSignificance
motif2.motif0.014883500000000001
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000617198
Pattern NameHomerSignificance
motif2.motif0.00030523299999999997
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037406199999999994
metacluster_1/pattern_30.019065099999999998
Pattern NameHomerSignificance
motif2.motif0.00245254
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.044651800000000005
Pattern NameHomerSignificance
motif3.motif0.0260373
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_61.49607e-11
Pattern NameHomerSignificance
motif11.motif0.000911311
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.020206000000000002
metacluster_1/pattern_30.058823900000000005
metacluster_1/pattern_120.0371455
metacluster_1/pattern_150.0385944
Pattern NameHomerSignificance
motif2.motif0.000595895
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00113501
Pattern NameHomerSignificance
motif3.motif0.00180632
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_63.1126299999999996e-06
Pattern NameHomerSignificance
motif11.motif0.00357243
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000158026
metacluster_1/pattern_120.0332192
Pattern NameHomerSignificance
motif2.motif0.000222697
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000486253
Pattern NameHomerSignificance
motif3.motif0.00549814
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_106.738450000000001e-06
Pattern NameHomerSignificance
motif14.motif0.000561191
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_90.00470541
Pattern NameHomerSignificance
motif2.motif0.00451446
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0005281169999999999
Pattern NameHomerSignificance
motif2.motif0.054726199999999996
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_06.477230000000001e-16
Pattern NameHomerSignificance
motif1.motif0.000523503
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0207058
Pattern NameHomerSignificance
motif3.motif0.0255136
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.014201599999999998
metacluster_1/pattern_30.000158026
metacluster_1/pattern_120.0517597
Pattern NameHomerSignificance
motif2.motif0.00340897
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_92.20767e-05
Pattern NameHomerSignificance
motif2.motif0.0528509
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00351255
metacluster_1/pattern_30.0005281169999999999
metacluster_1/pattern_120.00572388
metacluster_1/pattern_150.042996
Pattern NameHomerSignificance
motif2.motif0.00030523299999999997
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000460676
metacluster_1/pattern_100.00203824
Pattern NameHomerSignificance
motif3.motif0.012139299999999999
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_63.1126299999999996e-06
Pattern NameHomerSignificance
motif11.motif0.00357243
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00152656
metacluster_1/pattern_100.0542884
Pattern NameHomerSignificance
motif3.motif0.0333715
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0144458
metacluster_1/pattern_30.00841675
Pattern NameHomerSignificance
motif2.motif0.000431156
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0487976
metacluster_1/pattern_30.0008784960000000001
Pattern NameHomerSignificance
motif2.motif0.0359009
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_21.15752e-05
metacluster_1/pattern_100.0542884
Pattern NameHomerSignificance
motif3.motif0.00180632
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_135.5257900000000005e-18
Pattern NameHomerSignificance
motif5.motif5.90929e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00955272
Pattern NameHomerSignificance
motif14.motif0.017156499999999998
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0371184
metacluster_1/pattern_37.28841e-05
Pattern NameHomerSignificance
motif2.motif0.000222697
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.816260000000001e-06
metacluster_1/pattern_100.00212318
Pattern NameHomerSignificance
motif3.motif0.000289751
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.000520328
Pattern NameHomerSignificance
motif2.motif0.000275456
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.015903
Pattern NameHomerSignificance
motif3.motif0.00180632
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.013978999999999998
metacluster_1/pattern_30.045173000000000005
metacluster_1/pattern_120.037615800000000005
Pattern NameHomerSignificance
motif2.motif0.010581299999999998
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00320441
metacluster_1/pattern_30.045173000000000005
Pattern NameHomerSignificance
motif2.motif0.00407234
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0005868140000000001
Pattern NameHomerSignificance
motif3.motif0.0255136
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000271747
metacluster_1/pattern_90.0160118
Pattern NameHomerSignificance
motif2.motif0.00030523299999999997
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.057924300000000005
metacluster_1/pattern_30.035829400000000004
Pattern NameHomerSignificance
motif2.motif0.00712982
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.037038800000000004
metacluster_1/pattern_90.0013725999999999999
Pattern NameHomerSignificance
motif2.motif0.032207
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0180845
metacluster_1/pattern_30.058823900000000005
metacluster_1/pattern_98.11025e-05
Pattern NameHomerSignificance
motif2.motif0.00712982
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0393653
metacluster_1/pattern_95.37258e-07
Pattern NameHomerSignificance
motif2.motif0.00813507
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00023936700000000001
metacluster_1/pattern_30.042508
metacluster_1/pattern_95.78161e-06
Pattern NameHomerSignificance
motif2.motif0.00030523299999999997
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.07462e-07
Pattern NameHomerSignificance
motif10.motif0.00158968
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0227051
metacluster_1/pattern_30.0005653359999999999
Pattern NameHomerSignificance
motif2.motif0.00271743
Unique TF-MoDISco TFs: #82
TF NameModiscoHomer
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0157519
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0226179
metacluster_1/pattern_100.0554725
Absent
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00921048
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.052887800000000006
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00745151
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00813025
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00166926
Absent
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00252452
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_118.0175e-08
Absent
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.05436030000000001
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0483499
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0301839
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_111.00468e-07
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_164.23145e-08
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00011439600000000001
Absent
E2f3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.058823900000000005
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0340026
metacluster_1/pattern_100.00203824
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_95.78161e-06
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00444958
Absent
Mbd2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.047445999999999995
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_40.041509500000000005
metacluster_1/pattern_110.00210276
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_40.011284899999999999
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_110.059112
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0196387
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0129708
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.000966093
Absent
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000127633
Absent
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0517597
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0213741
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000138805
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00245828
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0254488
Absent
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0269599
Absent
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_140.013833700000000003
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0157519
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_171.94056e-05
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00988528
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00185956
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_110.009910700000000001
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_40.041509500000000005
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_160.000837598
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00210276
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00112028
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_40.054860400000000004
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_175.8959199999999994e-06
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.016460699999999998
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_110.000765963
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.058797300000000004
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_40.00813025
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00745151
Absent
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0034856
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0340411
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0466639
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_40.04795580000000001
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00210276
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0318443
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.054860400000000004
metacluster_1/pattern_110.00364813
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00203824
metacluster_1/pattern_161.62241e-09
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0584358
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0157519
Absent
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00011075600000000001
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.031051
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_111.00468e-07
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00196197
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_111.60174e-05
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.011483499999999999
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0140929
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00558201
Absent
Gata5
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000189291
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_40.018258
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_40.011483499999999999
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_40.0123479
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0029006
Absent
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000720837
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_40.041509500000000005
Absent
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_146.84659e-05
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_40.013644299999999998
metacluster_1/pattern_110.009910700000000001
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_40.026337
Absent
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000242158
Absent
Unique Homer TFs: #1
TF NameModiscoHomer
Zbtb33Absent
Pattern NameHomerSignificance
motif20.motif0.00036273800000000004