# Parameters
data_name = "GC_B;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_11-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_11-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:41:46,098 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	GC B cells
Cell Group	B cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	134962	110759	10.2605	48983482	14687225	0.3	9157954	0.187	18547324	0.3788

Modelling Metadata

Metric	Value
auPRC	0.6025
Calibrated Recall at 50% FDR	0.196
Number of Positive Examples in Test Data	120801
Number of Negative Examples in Test Data	7950050
Imbalance Ratio in Test Data	0.015
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #22

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 6715 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4401 SequenceContrib ScoresHyp_Contrib Scores	Spib, Spi1, Irf8, Irf4, Spic, Etv2, Elf3, Ehf, Prdm1, Irf3, Ets1, Etv6, Etv4, Irf2, Irf1, Erg, Elf1, Etv3, Elf4, Elf2, XP_911724.4, Gabpa, Fli1, Elk1, Elf5, Elk4, Elk3, Etv1, Etv5
metacluster_1/pattern_2 # seqlets: 2844 SequenceContrib ScoresHyp_Contrib Scores	Sp2, Sp3, Sp4, Klf3, Sp1, Klf6, Zfx, Klf15, Klf1, E2f4, Egr1, Wt1, Zfp281, Zbtb17, Maz, Klf5, Sp5, Klf4, Klf7, Klf12, Klf8, Tfap2c, Egr2, Usf2, E2f1, Nr1h4, Ptf1a, E2f7
metacluster_1/pattern_3 # seqlets: 2136 SequenceContrib ScoresHyp_Contrib Scores	Irf7, Stat2, Zscan10, Stat1, Irf9
metacluster_1/pattern_4 # seqlets: 1651 SequenceContrib ScoresHyp_Contrib Scores	Fev, Spdef
metacluster_1/pattern_5 # seqlets: 1275 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_6 # seqlets: 1192 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_7 # seqlets: 765 SequenceContrib ScoresHyp_Contrib Scores	Pou2f2
metacluster_1/pattern_8 # seqlets: 618 SequenceContrib ScoresHyp_Contrib Scores	Pax5, Pax6
metacluster_1/pattern_9 # seqlets: 604 SequenceContrib ScoresHyp_Contrib Scores	Creb1, Atf2, Atf7, Atf1, Jdp2, Crem, Creb5, Usf1, Atf3, Fosl2, Rfx1, Hlf
metacluster_1/pattern_10 # seqlets: 555 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_11 # seqlets: 518 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_12 # seqlets: 486 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfp42
metacluster_1/pattern_13 # seqlets: 406 SequenceContrib ScoresHyp_Contrib Scores	Tfe3, Tfeb, Arntl, Tfec, Mitf, Bhlhe40, Clock, Arnt, Srebf1, Mlx, Srebf2, Npas2, Mxi1, Rxrg, Tcfl5, Bhlhe41, Rxrb, Creb3l2, Mycn, Max
metacluster_1/pattern_14 # seqlets: 406 SequenceContrib ScoresHyp_Contrib Scores	Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_15 # seqlets: 276 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 205 SequenceContrib ScoresHyp_Contrib Scores	Mef2a, Mef2d, Mef2c
metacluster_1/pattern_17 # seqlets: 179 SequenceContrib ScoresHyp_Contrib Scores	Rela, Ets2
metacluster_1/pattern_18 # seqlets: 124 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33
metacluster_1/pattern_19 # seqlets: 104 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_20 # seqlets: 102 SequenceContrib ScoresHyp_Contrib Scores	Ebf1, Prdm16
metacluster_1/pattern_21 # seqlets: 82 SequenceContrib ScoresHyp_Contrib Scores	Nfkb1, Relb, Nfkb2, Rel

Click here for Motifs by TF-MoDISco: #130

TF Name	Pattern(s)
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 3.76975e-15 metacluster_1/pattern_11 0.00104878
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 4.21398e-08 metacluster_1/pattern_2 0.00930856 metacluster_1/pattern_11 0.019102200000000003
Spib	Pattern Name Modisco Significance metacluster_1/pattern_1 3.5357e-07 metacluster_1/pattern_3 8.10736e-07 metacluster_1/pattern_4 0.030170299999999997 metacluster_1/pattern_15 0.00244405
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00129702 metacluster_1/pattern_3 0.00565358 metacluster_1/pattern_4 0.0545879 metacluster_1/pattern_15 0.00244405 metacluster_1/pattern_17 0.0243396
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_1 2.9916e-05 metacluster_1/pattern_3 2.45702e-12 metacluster_1/pattern_4 0.0351993 metacluster_1/pattern_15 0.00275479
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_1 3.29713e-05 metacluster_1/pattern_3 0.032104 metacluster_1/pattern_15 0.00253222
Spic	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00362655 metacluster_1/pattern_3 0.0473799 metacluster_1/pattern_4 0.055401099999999995 metacluster_1/pattern_15 0.0176915 metacluster_1/pattern_17 0.0513383
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0020152 metacluster_1/pattern_4 0.0008722360000000001 metacluster_1/pattern_17 0.00390259
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.0291676 metacluster_1/pattern_17 0.014231299999999999
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0539359 metacluster_1/pattern_4 0.011327799999999999 metacluster_1/pattern_17 0.0288005
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00403023 metacluster_1/pattern_3 0.00400033 metacluster_1/pattern_4 0.051534300000000005 metacluster_1/pattern_15 0.0394824
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00405468 metacluster_1/pattern_3 0.00132104
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0165488 metacluster_1/pattern_4 0.00016397 metacluster_1/pattern_17 0.0034729999999999995
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0160142 metacluster_1/pattern_4 0.031548900000000005
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.00868464
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00994114 metacluster_1/pattern_3 0.010879799999999998
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.011843600000000001 metacluster_1/pattern_3 9.32804e-06
Erg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.00016397 metacluster_1/pattern_17 0.0243396
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0162827 metacluster_1/pattern_4 3.0448499999999998e-05
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0162827 metacluster_1/pattern_4 0.000631555
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0168373 metacluster_1/pattern_4 0.00230371
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.00436203 metacluster_1/pattern_17 0.0366635
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.0008722360000000001
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0599335 metacluster_1/pattern_4 0.000647846
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.00019707900000000002 metacluster_1/pattern_17 0.014231299999999999
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.039887 metacluster_1/pattern_4 6.70781e-05
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0391408 metacluster_1/pattern_4 0.021442199999999998 metacluster_1/pattern_17 0.0157442
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0539359 metacluster_1/pattern_4 0.000115948 metacluster_1/pattern_17 0.0420611
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0391408 metacluster_1/pattern_4 0.00017957900000000002
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.000117676
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.00036945
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.8990200000000002e-14 metacluster_1/pattern_9 0.00261053 metacluster_1/pattern_12 2.9022199999999998e-05 metacluster_1/pattern_13 0.012709100000000001 metacluster_1/pattern_18 4.1665e-05
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 8.81883e-11 metacluster_1/pattern_9 0.042541 metacluster_1/pattern_12 0.000649237 metacluster_1/pattern_18 0.00035937699999999997
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00165344 metacluster_1/pattern_12 0.038483800000000006
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.50141e-08 metacluster_1/pattern_12 0.027413099999999996 metacluster_1/pattern_18 0.021636700000000002
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000667235 metacluster_1/pattern_9 0.00882609 metacluster_1/pattern_12 0.000111625 metacluster_1/pattern_13 0.013874000000000001 metacluster_1/pattern_18 0.00135902
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 2.27458e-06
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00396403 metacluster_1/pattern_6 0.038812599999999996 metacluster_1/pattern_9 0.00949058 metacluster_1/pattern_12 0.00463628 metacluster_1/pattern_13 0.05678380000000001 metacluster_1/pattern_18 0.015009100000000001
Klf15	Pattern Name Modisco Significance metacluster_1/pattern_2 1.4537e-05
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00016344799999999998
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000203865
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00717252
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000211355 metacluster_1/pattern_12 0.027413099999999996
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0007326160000000001
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000667235 metacluster_1/pattern_12 0.012629799999999998
Maz	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000680387 metacluster_1/pattern_12 0.027413099999999996
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000680387
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000701439
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00282913
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00153845
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00384148
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00396403
Tfap2c	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00696472
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0110191
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.023365900000000002 metacluster_1/pattern_9 2.3921399999999998e-05 metacluster_1/pattern_13 0.0252705 metacluster_1/pattern_18 0.059048300000000005
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.025913400000000003
Nr1h4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0324365 metacluster_1/pattern_13 0.0158703
Ptf1a	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0499205
E2f7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0513823
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00390741
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00390741
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00714633
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00861732
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00861732
Fev	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000739605
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_4 0.011327799999999999
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_5 2.49983e-10
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_5 8.74727e-06
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_5 9.34561e-06
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_5 1.23984e-05
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000160055
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_6 3.45321e-07
Pou2f2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00980301
Pax5	Pattern Name Modisco Significance metacluster_1/pattern_8 7.2395e-08
Pax6	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00016398
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0040938 metacluster_1/pattern_13 0.0334674
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00570418 metacluster_1/pattern_13 0.0334674
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0020986 metacluster_1/pattern_13 0.0206677
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0282786 metacluster_1/pattern_13 0.034495300000000007
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00313453 metacluster_1/pattern_13 0.0446772
Crem	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0339903 metacluster_1/pattern_13 0.05678380000000001
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00261053
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00732269 metacluster_1/pattern_13 0.0479745
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0293724
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0293724
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0325246 metacluster_1/pattern_12 0.027413099999999996 metacluster_1/pattern_13 0.0078893 metacluster_1/pattern_14 6.73755e-09
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_9 0.05893009999999999 metacluster_1/pattern_13 0.055795000000000004
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 1.3448e-20
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 4.1760800000000004e-20
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 5.69478e-14
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_12 3.3701599999999997e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_12 1.2486300000000001e-05
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0162713
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00365233
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0006115480000000001
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0205887
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00389428
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00192503
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0097883
Clock	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0393723
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0588548
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.054865199999999996
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_13 0.024249200000000002
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00513362
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00797362
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00945552
Rxrg	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0183123
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0187129
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_13 0.025515799999999998
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0332477
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.037266
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_13 0.042495
Max	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0461875
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00382905 metacluster_1/pattern_19 0.00154571
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_14 3.28099e-08 metacluster_1/pattern_19 9.94792e-08
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_14 0.000274645
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00163292 metacluster_1/pattern_19 0.049486199999999994
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00163292 metacluster_1/pattern_19 0.049486199999999994
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000174119
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_16 5.18945e-12
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_16 4.78415e-11
Rela	Pattern Name Modisco Significance metacluster_1/pattern_17 0.040333600000000004 metacluster_1/pattern_21 0.00023234599999999997
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0513383
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_18 4.1665e-05
Ebf1	Pattern Name Modisco Significance metacluster_1/pattern_20 0.00087444
Prdm16	Pattern Name Modisco Significance metacluster_1/pattern_20 0.00660708
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00014942299999999998
Relb	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00023234599999999997
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00024417
Rel	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00793018

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #73

TF Name	Modisco	Homer
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.00036945	Pattern Name Homer Significance motif2.motif 0.00141504
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.00868464	Pattern Name Homer Significance motif2.motif 0.00124585
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.00436203 metacluster_1/pattern_17 0.0366635	Pattern Name Homer Significance motif2.motif 0.0440385
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.0008722360000000001	Pattern Name Homer Significance motif2.motif 0.0005594430000000001
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_1 3.29713e-05 metacluster_1/pattern_3 0.032104 metacluster_1/pattern_15 0.00253222	Pattern Name Homer Significance motif2.motif 0.00010661700000000001 motif8.motif 0.0064687
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00129702 metacluster_1/pattern_3 0.00565358 metacluster_1/pattern_4 0.0545879 metacluster_1/pattern_15 0.00244405 metacluster_1/pattern_17 0.0243396	Pattern Name Homer Significance motif2.motif 0.000127039
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00994114 metacluster_1/pattern_3 0.010879799999999998	Pattern Name Homer Significance motif2.motif 0.00475274 motif8.motif 0.00116024
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0391408 metacluster_1/pattern_4 0.021442199999999998 metacluster_1/pattern_17 0.0157442	Pattern Name Homer Significance motif2.motif 0.031177899999999998
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0539359 metacluster_1/pattern_4 0.000115948 metacluster_1/pattern_17 0.0420611	Pattern Name Homer Significance motif2.motif 0.000867457
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.039887 metacluster_1/pattern_4 6.70781e-05	Pattern Name Homer Significance motif2.motif 0.0009022069999999999
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 5.69478e-14	Pattern Name Homer Significance motif5.motif 7.27172e-05
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0162827 metacluster_1/pattern_4 0.000631555	Pattern Name Homer Significance motif2.motif 0.000531617
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000701439	Pattern Name Homer Significance motif3.motif 0.0383667
Spic	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00362655 metacluster_1/pattern_3 0.0473799 metacluster_1/pattern_4 0.055401099999999995 metacluster_1/pattern_15 0.0176915 metacluster_1/pattern_17 0.0513383	Pattern Name Homer Significance motif2.motif 0.000158426
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 4.1760800000000004e-20	Pattern Name Homer Significance motif5.motif 6.519190000000001e-07
Spib	Pattern Name Modisco Significance metacluster_1/pattern_1 3.5357e-07 metacluster_1/pattern_3 8.10736e-07 metacluster_1/pattern_4 0.030170299999999997 metacluster_1/pattern_15 0.00244405	Pattern Name Homer Significance motif2.motif 1.4186199999999998e-05 motif8.motif 0.010991500000000001
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000160055	Pattern Name Homer Significance motif10.motif 0.00296245
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0110191	Pattern Name Homer Significance motif3.motif 0.030608299999999998
Klf15	Pattern Name Modisco Significance metacluster_1/pattern_2 1.4537e-05	Pattern Name Homer Significance motif3.motif 0.00947369
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000680387	Pattern Name Homer Significance motif3.motif 0.0090241
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0391408 metacluster_1/pattern_4 0.00017957900000000002	Pattern Name Homer Significance motif2.motif 0.00124585
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00313453 metacluster_1/pattern_13 0.0446772	Pattern Name Homer Significance motif7.motif 0.053115800000000005
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_1 2.9916e-05 metacluster_1/pattern_3 2.45702e-12 metacluster_1/pattern_4 0.0351993 metacluster_1/pattern_15 0.00275479	Pattern Name Homer Significance motif2.motif 9.776950000000001e-05 motif8.motif 0.00103692
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 2.27458e-06	Pattern Name Homer Significance motif3.motif 0.00182195
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00390741	Pattern Name Homer Significance motif8.motif 0.010991500000000001
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_5 2.49983e-10	Pattern Name Homer Significance motif10.motif 6.014869999999999e-06
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.011843600000000001 metacluster_1/pattern_3 9.32804e-06	Pattern Name Homer Significance motif2.motif 0.008048600000000001 motif8.motif 0.00103692
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 8.81883e-11 metacluster_1/pattern_9 0.042541 metacluster_1/pattern_12 0.000649237 metacluster_1/pattern_18 0.00035937699999999997	Pattern Name Homer Significance motif3.motif 8.659870000000001e-05
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.025913400000000003	Pattern Name Homer Significance motif3.motif 0.00420704
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 1.3448e-20	Pattern Name Homer Significance motif5.motif 3.7438300000000005e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_12 1.2486300000000001e-05	Pattern Name Homer Significance motif15.motif 0.00546099
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0020152 metacluster_1/pattern_4 0.0008722360000000001 metacluster_1/pattern_17 0.00390259	Pattern Name Homer Significance motif2.motif 0.0005436659999999999
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00396403	Pattern Name Homer Significance motif3.motif 0.000688962
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000667235 metacluster_1/pattern_12 0.012629799999999998	Pattern Name Homer Significance motif3.motif 0.0024254000000000003
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000667235 metacluster_1/pattern_9 0.00882609 metacluster_1/pattern_12 0.000111625 metacluster_1/pattern_13 0.013874000000000001 metacluster_1/pattern_18 0.00135902	Pattern Name Homer Significance motif3.motif 0.00290044
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0007326160000000001	Pattern Name Homer Significance motif3.motif 0.0383667
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.8990200000000002e-14 metacluster_1/pattern_9 0.00261053 metacluster_1/pattern_12 2.9022199999999998e-05 metacluster_1/pattern_13 0.012709100000000001 metacluster_1/pattern_18 4.1665e-05	Pattern Name Homer Significance motif3.motif 7.81562e-05
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.50141e-08 metacluster_1/pattern_12 0.027413099999999996 metacluster_1/pattern_18 0.021636700000000002	Pattern Name Homer Significance motif3.motif 0.00037289999999999996
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0165488 metacluster_1/pattern_4 0.00016397 metacluster_1/pattern_17 0.0034729999999999995	Pattern Name Homer Significance motif2.motif 0.000489077
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0162827 metacluster_1/pattern_4 3.0448499999999998e-05	Pattern Name Homer Significance motif2.motif 0.000585492
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0168373 metacluster_1/pattern_4 0.00230371	Pattern Name Homer Significance motif2.motif 0.00069806
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00153845	Pattern Name Homer Significance motif3.motif 0.000419583
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_5 1.23984e-05	Pattern Name Homer Significance motif10.motif 0.00797961
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 4.21398e-08 metacluster_1/pattern_2 0.00930856 metacluster_1/pattern_11 0.019102200000000003	Pattern Name Homer Significance motif1.motif 9.848049999999999e-05
Erg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.00016397 metacluster_1/pattern_17 0.0243396	Pattern Name Homer Significance motif2.motif 0.0005594430000000001
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_4 0.011327799999999999	Pattern Name Homer Significance motif2.motif 0.024234799999999997
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00405468 metacluster_1/pattern_3 0.00132104	Pattern Name Homer Significance motif2.motif 0.00839257
Fev	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000739605	Pattern Name Homer Significance motif2.motif 0.010346
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00165344 metacluster_1/pattern_12 0.038483800000000006	Pattern Name Homer Significance motif3.motif 0.012352600000000002
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0293724	Pattern Name Homer Significance motif7.motif 0.053382799999999994
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.00019707900000000002 metacluster_1/pattern_17 0.014231299999999999	Pattern Name Homer Significance motif2.motif 0.00163641
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0160142 metacluster_1/pattern_4 0.031548900000000005	Pattern Name Homer Significance motif2.motif 0.00621771
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00282913	Pattern Name Homer Significance motif3.motif 0.030608299999999998
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0599335 metacluster_1/pattern_4 0.000647846	Pattern Name Homer Significance motif2.motif 0.00839045
Pou2f2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00980301	Pattern Name Homer Significance motif4.motif 0.000734348
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00403023 metacluster_1/pattern_3 0.00400033 metacluster_1/pattern_4 0.051534300000000005 metacluster_1/pattern_15 0.0394824	Pattern Name Homer Significance motif2.motif 0.00449604 motif8.motif 0.00725889
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_12 3.3701599999999997e-06	Pattern Name Homer Significance motif15.motif 0.000507172
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_6 3.45321e-07	Pattern Name Homer Significance motif12.motif 6.604130000000001e-05
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000203865	Pattern Name Homer Significance motif3.motif 0.000524731
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0539359 metacluster_1/pattern_4 0.011327799999999999 metacluster_1/pattern_17 0.0288005	Pattern Name Homer Significance motif2.motif 0.00439026
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_5 9.34561e-06	Pattern Name Homer Significance motif10.motif 0.00015534
E2f7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0513823	Pattern Name Homer Significance motif3.motif 0.00928128
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0188922 metacluster_1/pattern_4 0.0291676 metacluster_1/pattern_17 0.014231299999999999	Pattern Name Homer Significance motif2.motif 0.0110668
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0293724	Pattern Name Homer Significance motif7.motif 0.053382799999999994
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_5 8.74727e-06	Pattern Name Homer Significance motif10.motif 0.00015534
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00016344799999999998	Pattern Name Homer Significance motif3.motif 0.054174400000000004
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00384148	Pattern Name Homer Significance motif3.motif 0.036617199999999996
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 3.76975e-15 metacluster_1/pattern_11 0.00104878	Pattern Name Homer Significance motif1.motif 1.91016e-06
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00390741	Pattern Name Homer Significance motif8.motif 0.030249599999999998
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00717252	Pattern Name Homer Significance motif3.motif 0.0055623999999999995
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0040938 metacluster_1/pattern_13 0.0334674	Pattern Name Homer Significance motif7.motif 0.00459584
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.055273699999999995 metacluster_1/pattern_4 0.000117676	Pattern Name Homer Significance motif2.motif 0.0015993000000000001
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_18 4.1665e-05	Pattern Name Homer Significance motif14.motif 0.00650199

Unique TF-MoDISco TFs: #57

TF Name	Modisco	Homer
Rxrg	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0183123	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0006115480000000001	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.054865199999999996	Absent
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00570418 metacluster_1/pattern_13 0.0334674	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0393723	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_14 0.000274645	Absent
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00014942299999999998	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00382905 metacluster_1/pattern_19 0.00154571	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_14 3.28099e-08 metacluster_1/pattern_19 9.94792e-08	Absent
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00861732	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00163292 metacluster_1/pattern_19 0.049486199999999994	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0187129	Absent
Prdm16	Pattern Name Modisco Significance metacluster_1/pattern_20 0.00660708	Absent
Crem	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0339903 metacluster_1/pattern_13 0.05678380000000001	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00396403 metacluster_1/pattern_6 0.038812599999999996 metacluster_1/pattern_9 0.00949058 metacluster_1/pattern_12 0.00463628 metacluster_1/pattern_13 0.05678380000000001 metacluster_1/pattern_18 0.015009100000000001	Absent
Rela	Pattern Name Modisco Significance metacluster_1/pattern_17 0.040333600000000004 metacluster_1/pattern_21 0.00023234599999999997	Absent
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0162713	Absent
Nr1h4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0324365 metacluster_1/pattern_13 0.0158703	Absent
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.037266	Absent
Tfap2c	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00696472	Absent
Pax6	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00016398	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00797362	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000211355 metacluster_1/pattern_12 0.027413099999999996	Absent
Ebf1	Pattern Name Modisco Significance metacluster_1/pattern_20 0.00087444	Absent
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0020986 metacluster_1/pattern_13 0.0206677	Absent
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00261053	Absent
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_9 0.05893009999999999 metacluster_1/pattern_13 0.055795000000000004	Absent
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00365233	Absent
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00945552	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00389428	Absent
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00714633	Absent
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0332477	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00513362	Absent
Ptf1a	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0499205	Absent
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0513383	Absent
Maz	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000680387 metacluster_1/pattern_12 0.027413099999999996	Absent
Pax5	Pattern Name Modisco Significance metacluster_1/pattern_8 7.2395e-08	Absent
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00192503	Absent
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00861732	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_13 0.024249200000000002	Absent
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0588548	Absent
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000174119	Absent
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_16 4.78415e-11	Absent
Max	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0461875	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00163292 metacluster_1/pattern_19 0.049486199999999994	Absent
Rel	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00793018	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0325246 metacluster_1/pattern_12 0.027413099999999996 metacluster_1/pattern_13 0.0078893 metacluster_1/pattern_14 6.73755e-09	Absent
Relb	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00023234599999999997	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0097883	Absent
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0282786 metacluster_1/pattern_13 0.034495300000000007	Absent
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_16 5.18945e-12	Absent
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00732269 metacluster_1/pattern_13 0.0479745	Absent
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_13 0.042495	Absent
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.023365900000000002 metacluster_1/pattern_9 2.3921399999999998e-05 metacluster_1/pattern_13 0.0252705 metacluster_1/pattern_18 0.059048300000000005	Absent
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_21 0.00024417	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_13 0.025515799999999998	Absent
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0205887	Absent

Unique Homer TFs: #6

TF Name	Modisco	Homer
Zic3	Absent	Pattern Name Homer Significance motif1.motif 0.0565565
Zbtb1	Absent	Pattern Name Homer Significance motif3.motif 0.012352600000000002
Zic2	Absent	Pattern Name Homer Significance motif1.motif 0.055550800000000004
E2f6	Absent	Pattern Name Homer Significance motif3.motif 0.036617199999999996
Pou5f1	Absent	Pattern Name Homer Significance motif4.motif 0.0113403
Nanog	Absent	Pattern Name Homer Significance motif4.motif 0.057531399999999996