In [1]:
# Parameters
data_name = "DP3a;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_47-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_47-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:50:30,981 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeDN3a
    Cell GroupT cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep115465211598611.88944152129498457690.237254800600.132154010780.3711
    Modelling Metadata
    MetricValue
    auPRC0.5771
    Calibrated Recall at 50% FDR0.238
    Number of Positive Examples in Test Data126544
    Number of Negative Examples in Test Data7944307
    Imbalance Ratio in Test Data0.0157
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #20
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5526 SequenceContrib ScoresHyp_Contrib Scores
Ets1, Erg, Etv4, Etv2, Elk1, Elk4, Fli1, Gabpa, Spi1, Etv6,

Elf2, Ehf, Etv5, Elk3, Spib, Elf1, Elf3, Fev, Etv3, XP_911724.4, Etv1,

Ets2, Elf4, Irf8, Irf4, Stat4, Elf5, Spic
metacluster_1/pattern_1 # seqlets: 5362 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 3096 SequenceContrib ScoresHyp_Contrib Scores
Sp2, Sp3, Sp4, Klf3, Sp1, Klf6, E2f4, Klf4, Sp5, Klf7,

Egr1, Zbtb17, Klf5, Klf8, Klf12, Wt1, Egr2, Zfp281, Klf1, Maz, E2f1,

Klf15, Srebf2
metacluster_1/pattern_3 # seqlets: 2145 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_4 # seqlets: 1429 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1015 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Prdm1, Stat1, Irf3, Irf7, Stat2, Irf9, Batf3
metacluster_1/pattern_6 # seqlets: 1011 SequenceContrib ScoresHyp_Contrib Scores
Nrf1, Zfx
metacluster_1/pattern_7 # seqlets: 779 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_8 # seqlets: 779 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_9 # seqlets: 549 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Rfx1, Zfp42, Mxi1
metacluster_1/pattern_10 # seqlets: 534 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Usf2, Atf2, Atf7, Jdp2, Crem, Atf1, Creb5, Atf3, Usf1,

Fosl2, Hlf, Nfil3
metacluster_1/pattern_11 # seqlets: 457 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_12 # seqlets: 404 SequenceContrib ScoresHyp_Contrib Scores
Tfe3, Tfec, Tfeb, Arntl, Mitf, Srebf1, Bhlhe40, Clock, Mlx, Arnt,

Npas2, Tcfl5, Creb3l2, Mycn, Max, Bhlhe41, Myc, Dbp, Mlxip, Xbp1
metacluster_1/pattern_13 # seqlets: 288 SequenceContrib ScoresHyp_Contrib Scores
Rfx2, Rfx3, Rfx4, Rfx7, Rfx6, Sox2, Pou5f1
metacluster_1/pattern_14 # seqlets: 196 SequenceContrib ScoresHyp_Contrib Scores
Bach2, Nfe2l2, Nfe2, Bach1, Mafk, Mafa, Mafb, Mafg, Maff, Jun,

Maf, Fosb, Fosl1, Junb, Jund, Batf, Fos
metacluster_1/pattern_15 # seqlets: 151 SequenceContrib ScoresHyp_Contrib Scores
Gata3, Gata4, Mecom
metacluster_1/pattern_16 # seqlets: 92 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_17 # seqlets: 69 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib
metacluster_1/pattern_18 # seqlets: 54 SequenceContrib ScoresHyp_Contrib Scores
Rest
metacluster_1/pattern_19 # seqlets: 42 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #146
TF NamePattern(s)
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.006551899999999999
metacluster_1/pattern_70.0595283
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00715663
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_01.5171800000000001e-05
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00818184
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00922575
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.006551899999999999
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0498848
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00446215
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.029709500000000003
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0385791
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00276717
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00276717
metacluster_1/pattern_50.000278359
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00368433
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0515057
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0037711999999999997
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00843361
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.015902799999999998
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0175872
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0179988
metacluster_1/pattern_51.1231500000000001e-07
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.022359099999999996
metacluster_1/pattern_59.034479999999999e-05
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.024036099999999998
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0369862
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0425841
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_16.61775e-16
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_17.36483e-08
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_21.23997e-08
metacluster_1/pattern_95.49783e-05
metacluster_1/pattern_100.00186324
metacluster_1/pattern_160.0343513
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.259999999999999e-08
metacluster_1/pattern_90.00139835
metacluster_1/pattern_100.0418092
metacluster_1/pattern_160.0343513
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00131165
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_22.76761e-07
metacluster_1/pattern_90.0341445
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000378411
metacluster_1/pattern_95.49783e-05
metacluster_1/pattern_100.024300400000000003
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000339499
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000339499
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00131165
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000978626
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000994495
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.019412400000000003
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00120656
metacluster_1/pattern_90.0207817
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00131165
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00144092
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00186249
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00264638
metacluster_1/pattern_90.0326063
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00443868
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00651631
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0277777
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00943214
metacluster_1/pattern_90.0341445
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0225421
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_20.023196599999999998
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0516686
metacluster_1/pattern_120.00357996
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_34.66546e-05
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0132067
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000249468
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00261968
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0212087
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_41.33915e-15
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_41.0279700000000001e-10
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_44.73421e-10
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.95539e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_45.18174e-06
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.8257300000000001e-13
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0016026
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.85697e-05
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.37019e-05
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_56.21049e-05
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000125748
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000763566
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00165901
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0339591
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_69.389630000000001e-06
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0252916
metacluster_1/pattern_90.00908896
metacluster_1/pattern_100.010531
metacluster_1/pattern_160.0343513
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_82.52606e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_85.0761199999999994e-20
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_81.40992e-13
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_97.40418e-06
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_92.0738499999999998e-05
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0109611
metacluster_1/pattern_100.0304502
metacluster_1/pattern_131.35066e-07
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0207817
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0503009
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00295931
metacluster_1/pattern_120.038375400000000004
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_102.3592399999999998e-05
metacluster_1/pattern_120.005559000000000001
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00121839
metacluster_1/pattern_120.038375400000000004
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000460322
metacluster_1/pattern_120.0201261
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00105449
metacluster_1/pattern_120.038375400000000004
metacluster_1/pattern_140.0105243
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_100.012794499999999999
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0227297
metacluster_1/pattern_120.0201261
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000460322
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00833017
metacluster_1/pattern_140.00173263
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00833017
metacluster_1/pattern_120.00994722
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.014736500000000001
metacluster_1/pattern_140.00321474
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.03390580000000001
metacluster_1/pattern_120.026999900000000004
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0383106
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000964322
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000964322
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000276659
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0092157
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0005627890000000001
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0294033
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00753189
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.031177299999999998
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00783866
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0420147
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00392715
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00628241
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0227299
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0117609
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0141793
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0181114
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0227299
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0436005
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0483305
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0483608
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0286882
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000926738
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_139.622319999999999e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000662595
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000775231
Sox2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.053897400000000005
Pou5f1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0388921
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_141.7679e-07
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_142.2098700000000002e-07
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_142.2098700000000002e-07
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_143.44394e-05
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000475861
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000475861
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00128097
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00263882
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00268944
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00315115
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.054686900000000004
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0419106
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00410866
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.010493
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0561625
Mecom
Pattern NameModiscoSignificance
metacluster_1/pattern_150.05166849999999999
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_161.61697e-05
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_177.981289999999999e-06
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0211114
Rest
Pattern NameModiscoSignificance
metacluster_1/pattern_181.01691e-15
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #84
TF NameModiscoHomer
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000249468
Pattern NameHomerSignificance
motif3.motif0.0196779
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00120656
metacluster_1/pattern_90.0207817
Pattern NameHomerSignificance
motif4.motif0.018991499999999998
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.8257300000000001e-13
Pattern NameHomerSignificance
motif8.motif0.00481831
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_21.23997e-08
metacluster_1/pattern_95.49783e-05
metacluster_1/pattern_100.00186324
metacluster_1/pattern_160.0343513
Pattern NameHomerSignificance
motif4.motif0.00302515
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Pattern NameHomerSignificance
motif2.motif0.00435226
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_100.012794499999999999
Pattern NameHomerSignificance
motif21.motif0.0442746
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00833017
metacluster_1/pattern_120.00994722
Pattern NameHomerSignificance
motif21.motif0.038567699999999996
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_41.95539e-06
Pattern NameHomerSignificance
motif13.motif0.00118751
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_41.0279700000000001e-10
Pattern NameHomerSignificance
motif13.motif0.0008503460000000001
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_69.389630000000001e-06
Pattern NameHomerSignificance
motif11.motif1.53834e-06
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00922575
Pattern NameHomerSignificance
motif2.motif0.00352946
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0117609
Pattern NameHomerSignificance
motif21.motif0.054077
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00818184
Pattern NameHomerSignificance
motif2.motif0.00435226
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00276717
Pattern NameHomerSignificance
motif2.motif0.00144561
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Pattern NameHomerSignificance
motif2.motif0.00352946
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.022359099999999996
metacluster_1/pattern_59.034479999999999e-05
Pattern NameHomerSignificance
motif8.motif0.0368352
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00144092
Pattern NameHomerSignificance
motif4.motif0.00754594
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Pattern NameHomerSignificance
motif2.motif0.00352946
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00131165
Pattern NameHomerSignificance
motif4.motif0.040256400000000005
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00368433
Pattern NameHomerSignificance
motif2.motif0.00248138
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0175872
Pattern NameHomerSignificance
motif2.motif0.0164278
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000994495
Pattern NameHomerSignificance
motif4.motif0.00383115
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0016026
Pattern NameHomerSignificance
motif8.motif0.00891559
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.259999999999999e-08
metacluster_1/pattern_90.00139835
metacluster_1/pattern_100.0418092
metacluster_1/pattern_160.0343513
Pattern NameHomerSignificance
motif4.motif0.00302515
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_22.76761e-07
metacluster_1/pattern_90.0341445
Pattern NameHomerSignificance
motif4.motif0.00302515
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00715663
Pattern NameHomerSignificance
motif2.motif0.00306717
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000276659
Pattern NameHomerSignificance
motif21.motif0.000456856
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000339499
Pattern NameHomerSignificance
motif4.motif0.000429807
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0227299
Pattern NameHomerSignificance
motif21.motif0.0393093
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000460322
metacluster_1/pattern_120.0201261
Pattern NameHomerSignificance
motif21.motif0.0509133
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00753189
Pattern NameHomerSignificance
motif21.motif0.013105200000000003
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_102.3592399999999998e-05
metacluster_1/pattern_120.005559000000000001
Pattern NameHomerSignificance
motif21.motif0.027972300000000002
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_34.66546e-05
Pattern NameHomerSignificance
motif3.motif0.016923900000000002
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0225421
Pattern NameHomerSignificance
motif4.motif0.00302515
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000339499
Pattern NameHomerSignificance
motif4.motif0.00713142
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0277777
Pattern NameHomerSignificance
motif4.motif0.018991499999999998
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00392715
Pattern NameHomerSignificance
motif21.motif0.029125
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_41.33915e-15
Pattern NameHomerSignificance
motif13.motif0.000106546
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_45.18174e-06
Pattern NameHomerSignificance
motif13.motif0.00118751
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.006551899999999999
Pattern NameHomerSignificance
motif2.motif0.00306717
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00121839
metacluster_1/pattern_120.038375400000000004
Pattern NameHomerSignificance
motif21.motif0.0509133
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0385791
Pattern NameHomerSignificance
motif2.motif0.010693600000000001
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00165901
Pattern NameHomerSignificance
motif8.motif9.50156e-05
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Pattern NameHomerSignificance
motif2.motif0.006752299999999999
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_81.40992e-13
Pattern NameHomerSignificance
motif6.motif0.000270565
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0037711999999999997
Pattern NameHomerSignificance
motif2.motif0.00035621199999999996
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.019412400000000003
Pattern NameHomerSignificance
motif4.motif0.0255062
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0132067
Pattern NameHomerSignificance
motif3.motif0.0196779
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00726129
Pattern NameHomerSignificance
motif2.motif0.00352946
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.006551899999999999
metacluster_1/pattern_70.0595283
Pattern NameHomerSignificance
motif2.motif0.00246029
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00295931
metacluster_1/pattern_120.038375400000000004
Pattern NameHomerSignificance
motif21.motif0.0371384
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_20.023196599999999998
Pattern NameHomerSignificance
motif4.motif0.011627600000000002
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000125748
Pattern NameHomerSignificance
motif8.motif0.00284407
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000378411
metacluster_1/pattern_95.49783e-05
metacluster_1/pattern_100.024300400000000003
Pattern NameHomerSignificance
motif4.motif0.011876600000000001
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00186249
Pattern NameHomerSignificance
motif4.motif0.00852453
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.85697e-05
Pattern NameHomerSignificance
motif8.motif0.058087
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0294033
Pattern NameHomerSignificance
motif21.motif0.0286983
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_44.73421e-10
Pattern NameHomerSignificance
motif13.motif0.0008503460000000001
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0005627890000000001
Pattern NameHomerSignificance
motif21.motif0.00734761
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0516686
metacluster_1/pattern_120.00357996
Pattern NameHomerSignificance
motif21.motif0.00842175
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000964322
Pattern NameHomerSignificance
motif21.motif0.00431728
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00783866
Pattern NameHomerSignificance
motif21.motif0.0234314
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00261968
Pattern NameHomerSignificance
motif3.motif0.0225879
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00131165
Pattern NameHomerSignificance
motif4.motif0.0159829
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.029709500000000003
Pattern NameHomerSignificance
motif2.motif0.0413727
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_120.000964322
Pattern NameHomerSignificance
motif21.motif0.00450242
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0181114
Pattern NameHomerSignificance
motif21.motif0.0286983
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00843361
Pattern NameHomerSignificance
motif2.motif0.00435226
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0092157
Pattern NameHomerSignificance
motif21.motif0.021725900000000003
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_01.5171800000000001e-05
Pattern NameHomerSignificance
motif2.motif2.6456999999999998e-05
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_161.61697e-05
Pattern NameHomerSignificance
motif18.motif0.011203399999999999
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_82.52606e-21
Pattern NameHomerSignificance
motif6.motif7.81397e-05
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_85.0761199999999994e-20
Pattern NameHomerSignificance
motif6.motif2.74723e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_17.36483e-08
Pattern NameHomerSignificance
motif1.motif0.0005537340000000001
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_120.031177299999999998
Pattern NameHomerSignificance
motif21.motif0.00232345
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0369862
Pattern NameHomerSignificance
motif2.motif0.0561528
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0515057
Pattern NameHomerSignificance
motif2.motif0.0545851
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0498848
Pattern NameHomerSignificance
motif2.motif0.00776935
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0420147
Pattern NameHomerSignificance
motif21.motif0.00211924
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0179988
metacluster_1/pattern_51.1231500000000001e-07
Pattern NameHomerSignificance
motif8.motif0.058087
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_16.61775e-16
Pattern NameHomerSignificance
motif1.motif4.6171700000000004e-05
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.024036099999999998
Pattern NameHomerSignificance
motif2.motif0.0299041
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00446215
Pattern NameHomerSignificance
motif2.motif0.00347565
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00131165
Pattern NameHomerSignificance
motif4.motif0.018991499999999998
Unique TF-MoDISco TFs: #62
TF NameModiscoHomer
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_97.40418e-06
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0383106
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_50.000763566
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000475861
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000475861
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00410866
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0227299
Absent
Maf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00128097
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0339591
Absent
Rest
Pattern NameModiscoSignificance
metacluster_1/pattern_181.01691e-15
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0227297
metacluster_1/pattern_120.0201261
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_142.2098700000000002e-07
Absent
Gfi1b
Pattern NameModiscoSignificance
metacluster_1/pattern_30.0212087
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_177.981289999999999e-06
Absent
Maff
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Absent
Pou5f1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0388921
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00943214
metacluster_1/pattern_90.0341445
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_142.2098700000000002e-07
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000662595
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_141.7679e-07
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.014736500000000001
metacluster_1/pattern_140.00321474
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00651631
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_143.44394e-05
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_140.0419106
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0483608
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00268944
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.015902799999999998
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0207817
Absent
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_92.0738499999999998e-05
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0109611
metacluster_1/pattern_100.0304502
metacluster_1/pattern_131.35066e-07
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_139.622319999999999e-05
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000775231
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_140.054686900000000004
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00833017
metacluster_1/pattern_140.00173263
Absent
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0425841
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.37019e-05
Absent
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00276717
metacluster_1/pattern_50.000278359
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000926738
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0436005
Absent
Mecom
Pattern NameModiscoSignificance
metacluster_1/pattern_150.05166849999999999
Absent
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.010493
Absent
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0561625
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0286882
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.0211114
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0503009
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0252916
metacluster_1/pattern_90.00908896
metacluster_1/pattern_100.010531
metacluster_1/pattern_160.0343513
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00264638
metacluster_1/pattern_90.0326063
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00443868
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.03390580000000001
metacluster_1/pattern_120.026999900000000004
Absent
Sox2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.053897400000000005
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_120.00628241
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0141793
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00105449
metacluster_1/pattern_120.038375400000000004
metacluster_1/pattern_140.0105243
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_56.21049e-05
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.000460322
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_120.0483305
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000978626
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00263882
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00315115
Absent
Mafg
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000971199
Absent
Unique Homer TFs: #33
TF NameModiscoHomer
Meis3Absent
Pattern NameHomerSignificance
motif12.motif0.0212048
Bhlha15Absent
Pattern NameHomerSignificance
motif12.motif0.00959585
Ascl1Absent
Pattern NameHomerSignificance
motif12.motif0.0197804
Tcf3Absent
Pattern NameHomerSignificance
motif12.motif0.0307468
SpdefAbsent
Pattern NameHomerSignificance
motif2.motif0.0286579
MyogAbsent
Pattern NameHomerSignificance
motif12.motif0.00959585
Hes5Absent
Pattern NameHomerSignificance
motif12.motif0.0311707
Zbtb1Absent
Pattern NameHomerSignificance
motif4.motif0.040256400000000005
Myf6Absent
Pattern NameHomerSignificance
motif12.motif0.0161757
Pknox2Absent
Pattern NameHomerSignificance
motif12.motif0.0212048
Pknox1Absent
Pattern NameHomerSignificance
motif12.motif0.0390399
E2f7Absent
Pattern NameHomerSignificance
motif4.motif0.00439496
Nhlh2Absent
Pattern NameHomerSignificance
motif12.motif0.019734799999999997
Ascl2Absent
Pattern NameHomerSignificance
motif12.motif0.00959585
Tcf12Absent
Pattern NameHomerSignificance
motif12.motif0.0322484
Atoh1Absent
Pattern NameHomerSignificance
motif12.motif0.031463200000000004
Tgif1Absent
Pattern NameHomerSignificance
motif12.motif0.00889657
Zic2Absent
Pattern NameHomerSignificance
motif12.motif0.0596114
Tcf4Absent
Pattern NameHomerSignificance
motif12.motif0.025635900000000003
Myf5Absent
Pattern NameHomerSignificance
motif12.motif0.019734799999999997
Snai2Absent
Pattern NameHomerSignificance
motif12.motif0.019734799999999997
Tal1Absent
Pattern NameHomerSignificance
motif12.motif0.0190902
E2f6Absent
Pattern NameHomerSignificance
motif4.motif0.018991499999999998
Nhlh1Absent
Pattern NameHomerSignificance
motif12.motif0.0297645
Tcf7l1Absent
Pattern NameHomerSignificance
motif12.motif0.00484764
Meis2Absent
Pattern NameHomerSignificance
motif12.motif0.0309731
Irf5Absent
Pattern NameHomerSignificance
motif8.motif0.058087
Myod1Absent
Pattern NameHomerSignificance
motif12.motif0.026331099999999996
Neurod1Absent
Pattern NameHomerSignificance
motif12.motif0.0477485
Neurod2Absent
Pattern NameHomerSignificance
motif12.motif0.0453284
Snai1Absent
Pattern NameHomerSignificance
motif12.motif0.0472962
Tcf21Absent
Pattern NameHomerSignificance
motif12.motif0.0264931
Ptf1aAbsent
Pattern NameHomerSignificance
motif12.motif0.0297645