In [1]:
# Parameters
data_name = "wES;GRM;E16.5;A;GEO"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_179-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_179-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 19:21:06,412 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeE16.5 sorted germ cells(wt)
    Cell GroupES cells and embryonic tissues
    Experiment NameATAC
    Experiment GroupGEO
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep12090731197197.216590508387101873160.112651381990.0568286884740.317
    Modelling Metadata
    MetricValue
    auPRC0.4588
    Calibrated Recall at 50% FDR0.343
    Number of Positive Examples in Test Data80019
    Number of Negative Examples in Test Data7990832
    Imbalance Ratio in Test Data0.0099
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #34
Pattern NameTF Name(s)Modisco
metacluster_0/pattern_0 # seqlets: 1784 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp3, Sp2, Sp1, Klf3, Klf6, E2f4, Egr1, Sp5, Klf4,

Zbtb17, Klf7, Klf8, Klf1, Egr2, Klf12, Zfp281, Wt1, Nhlh1, Ptf1a, Klf15,

Klf5
metacluster_0/pattern_1 # seqlets: 1525 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_0/pattern_2 # seqlets: 1481 SequenceContrib ScoresHyp_Contrib Scores
Maz, Ctcfl, Zfx, Mxi1, Zfp740, E2f1, Rela, Sall4, Fli1, Zbtb1,

Srebf2, Gata1, Egr3
metacluster_0/pattern_3 # seqlets: 1366 SequenceContrib ScoresHyp_Contrib Scores
Nrf1, Usf2, Rfx1
metacluster_0/pattern_4 # seqlets: 1002 SequenceContrib ScoresHyp_Contrib Scores
Myc
metacluster_0/pattern_5 # seqlets: 869 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_6 # seqlets: 618 SequenceContrib ScoresHyp_Contrib Scores
Ctcf
metacluster_0/pattern_7 # seqlets: 610 SequenceContrib ScoresHyp_Contrib Scores
Gabpa, Elf1, Elk1, Ets1, Elk4, Erg, Elk3, Etv2, Etv1, Etv4,

Etv5, Elf4, Ehf, Elf2, Elf5, Etv3, Etv6, XP_911724.4, Elf3, Fev, Spdef,

Spi1
metacluster_0/pattern_8 # seqlets: 550 SequenceContrib ScoresHyp_Contrib Scores
Rfx6
metacluster_0/pattern_9 # seqlets: 430 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfeb, Tfe3, Tfec, Arntl, Mitf, Srebf1, Bhlhe40, Clock, Arnt,

Mlx, Mycn, Npas2, Tcfl5, Atf7, Atf2, Max, Creb3l2, Creb1, Rxrg, Bhlhe41,

Atf1
metacluster_0/pattern_10 # seqlets: 346 SequenceContrib ScoresHyp_Contrib Scores
Rfx3, Rfx2, Rfx4, Rfx7, Hic1
metacluster_0/pattern_11 # seqlets: 321 SequenceContrib ScoresHyp_Contrib Scores
Thap11, Zfp143, Tbx2
metacluster_0/pattern_12 # seqlets: 279 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_0/pattern_13 # seqlets: 277 SequenceContrib ScoresHyp_Contrib Scores
Crem, Jdp2, Creb5, Atf3, Fosl2, Jun
metacluster_0/pattern_14 # seqlets: 205 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_15 # seqlets: 197 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Zfp42
metacluster_0/pattern_16 # seqlets: 138 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_17 # seqlets: 129 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_18 # seqlets: 118 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_19 # seqlets: 114 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_20 # seqlets: 91 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_21 # seqlets: 77 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_22 # seqlets: 75 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_23 # seqlets: 88 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_24 # seqlets: 63 SequenceContrib ScoresHyp_Contrib Scores
Gli3, Bcl6, Gli2, Gli1
metacluster_0/pattern_25 # seqlets: 81 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_26 # seqlets: 50 SequenceContrib ScoresHyp_Contrib Scores
Vdr
metacluster_0/pattern_27 # seqlets: 46 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_28 # seqlets: 45 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_29 # seqlets: 41 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_30 # seqlets: 38 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_31 # seqlets: 36 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_32 # seqlets: 47 SequenceContrib ScoresHyp_Contrib Scores
metacluster_0/pattern_33 # seqlets: 55 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #113
TF NamePattern(s)
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0162657
metacluster_0/pattern_20.0007349289999999999
metacluster_0/pattern_50.028930900000000002
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000300454
metacluster_0/pattern_21.7552900000000003e-06
metacluster_0/pattern_30.00455855
metacluster_0/pattern_40.00122553
metacluster_0/pattern_53.27006e-07
metacluster_0/pattern_130.0157173
metacluster_0/pattern_150.0009649319999999999
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000300454
metacluster_0/pattern_25.781929999999999e-07
metacluster_0/pattern_36.82156e-05
metacluster_0/pattern_40.000108648
metacluster_0/pattern_53.4816199999999996e-08
metacluster_0/pattern_90.052478
metacluster_0/pattern_120.029388099999999997
metacluster_0/pattern_130.00156417
metacluster_0/pattern_155.0538e-05
metacluster_0/pattern_240.0374209
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0123929
metacluster_0/pattern_23.57105e-05
metacluster_0/pattern_30.0053234
metacluster_0/pattern_40.00122553
metacluster_0/pattern_57.111960000000001e-07
metacluster_0/pattern_130.013886700000000002
metacluster_0/pattern_150.00139077
metacluster_0/pattern_240.0143806
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005005459999999999
metacluster_0/pattern_21.3721600000000001e-05
metacluster_0/pattern_30.020687599999999997
metacluster_0/pattern_40.044097199999999996
metacluster_0/pattern_51.1359200000000001e-05
metacluster_0/pattern_150.0179894
metacluster_0/pattern_240.0386126
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00558393
metacluster_0/pattern_20.00125238
metacluster_0/pattern_50.00249864
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00642519
metacluster_0/pattern_20.000629446
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00832272
metacluster_0/pattern_20.054707000000000006
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00758559
metacluster_0/pattern_26.7288e-08
metacluster_0/pattern_50.028205
metacluster_0/pattern_240.00685763
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.057483900000000004
metacluster_0/pattern_29.67711e-05
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00889918
metacluster_0/pattern_23.86123e-05
metacluster_0/pattern_50.00249864
metacluster_0/pattern_150.0210949
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00889918
metacluster_0/pattern_28.060390000000001e-05
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.010162000000000001
metacluster_0/pattern_20.00011768899999999999
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.010442
metacluster_0/pattern_20.0232201
metacluster_0/pattern_50.0194038
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0123929
metacluster_0/pattern_20.0378904
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0142852
metacluster_0/pattern_20.054707000000000006
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0256848
metacluster_0/pattern_20.054707000000000006
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0294013
metacluster_0/pattern_24.85499e-06
metacluster_0/pattern_50.00952482
metacluster_0/pattern_240.0182506
Nhlh1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0330249
Ptf1a
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0465073
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0544414
metacluster_0/pattern_29.27409e-05
metacluster_0/pattern_50.00529472
metacluster_0/pattern_240.0143806
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0554235
metacluster_0/pattern_28.44641e-05
metacluster_0/pattern_50.00272083
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_12.67768e-12
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_14.37495e-11
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_19.17273e-10
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_17.698569999999999e-07
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_14.82216e-06
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_21.3721600000000001e-05
metacluster_0/pattern_50.036313599999999994
metacluster_0/pattern_240.00685763
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_20.004996899999999999
metacluster_0/pattern_40.0282392
metacluster_0/pattern_50.00688997
metacluster_0/pattern_69.14213e-11
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00622289
metacluster_0/pattern_30.0150977
metacluster_0/pattern_40.054464599999999995
metacluster_0/pattern_50.0399588
metacluster_0/pattern_90.0241766
metacluster_0/pattern_120.029388099999999997
metacluster_0/pattern_130.0294083
metacluster_0/pattern_150.00667203
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0250623
metacluster_0/pattern_30.0229395
metacluster_0/pattern_40.016470699999999998
metacluster_0/pattern_50.00688997
metacluster_0/pattern_90.00134195
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0284186
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0370556
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0440615
metacluster_0/pattern_240.0386126
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.045513599999999994
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0466469
metacluster_0/pattern_70.00066518
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0471364
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_20.054707000000000006
metacluster_0/pattern_90.00699862
metacluster_0/pattern_130.0531284
Gata1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.054707000000000006
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0575059
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_37.40317e-06
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0324387
metacluster_0/pattern_40.00446319
metacluster_0/pattern_50.00250827
metacluster_0/pattern_90.00789368
metacluster_0/pattern_120.0432525
metacluster_0/pattern_133.8158200000000003e-05
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0474479
metacluster_0/pattern_40.024781400000000002
metacluster_0/pattern_50.00688997
metacluster_0/pattern_90.051167800000000006
metacluster_0/pattern_101.70573e-09
metacluster_0/pattern_130.052003999999999995
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0485087
metacluster_0/pattern_90.0503272
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_62.09801e-08
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000555453
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_71.41306e-06
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000225181
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00066518
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000555453
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000589553
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000271044
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000555453
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000567755
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00967032
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000567755
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000589553
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00398763
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00113604
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_70.013831200000000002
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00155166
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0488648
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00185989
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0229012
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00500539
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_70.026119200000000002
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.036104699999999997
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00201112
metacluster_0/pattern_100.00162886
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.016751099999999998
metacluster_0/pattern_130.011074200000000001
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_90.000175728
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0008051089999999999
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0009237010000000001
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0146232
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0006660230000000001
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0502151
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_90.019663200000000002
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00106562
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_90.059068899999999994
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00785116
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0536212
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00789368
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0125435
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0163495
metacluster_0/pattern_130.00101496
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.017999599999999998
metacluster_0/pattern_130.00249508
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0241766
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.03723680000000001
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.033306699999999995
metacluster_0/pattern_130.00249508
Rxrg
Pattern NameModiscoSignificance
metacluster_0/pattern_90.039217400000000006
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0453654
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0473042
metacluster_0/pattern_130.013306799999999999
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0127401
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_101.66391e-07
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000664934
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00489758
Hic1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0557434
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_111.33749e-19
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_114.54406e-19
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_118.71606e-13
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_123.15639e-05
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0253036
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00190222
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00179561
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0366054
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.029240199999999997
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0462079
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_154.38601e-06
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_154.38601e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_150.00667203
Gli3
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0282348
Bcl6
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0386126
Gli2
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0386126
Gli1
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0409777
Vdr
Pattern NameModiscoSignificance
metacluster_0/pattern_260.0124796
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #63
TF NameModiscoHomer
Rfx3
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0127401
Pattern NameHomerSignificance
motif7.motif0.0203837
Elk1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000225181
Pattern NameHomerSignificance
motif6.motif0.00721875
Klf4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.057483900000000004
metacluster_0/pattern_29.67711e-05
Pattern NameHomerSignificance
motif1.motif0.0069001
Klf15
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0544414
metacluster_0/pattern_29.27409e-05
metacluster_0/pattern_50.00529472
metacluster_0/pattern_240.0143806
Pattern NameHomerSignificance
motif1.motif0.00994466
Fev
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00500539
Pattern NameHomerSignificance
motif6.motif0.011742200000000001
Etv5
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000567755
Pattern NameHomerSignificance
motif6.motif0.00455773
Crem
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0253036
Pattern NameHomerSignificance
motif12.motif0.0191254
Thap11
Pattern NameModiscoSignificance
metacluster_0/pattern_111.33749e-19
Pattern NameHomerSignificance
motif4.motif1.34762e-07
Sp1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0123929
metacluster_0/pattern_23.57105e-05
metacluster_0/pattern_30.0053234
metacluster_0/pattern_40.00122553
metacluster_0/pattern_57.111960000000001e-07
metacluster_0/pattern_130.013886700000000002
metacluster_0/pattern_150.00139077
metacluster_0/pattern_240.0143806
Pattern NameHomerSignificance
motif1.motif0.0477972
Rfx4
Pattern NameModiscoSignificance
metacluster_0/pattern_100.000664934
Pattern NameHomerSignificance
motif7.motif0.0488267
Nfya
Pattern NameModiscoSignificance
metacluster_0/pattern_19.17273e-10
Pattern NameHomerSignificance
motif2.motif1.79584e-11
XP_911724.4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00185989
Pattern NameHomerSignificance
motif6.motif0.0078124
Creb1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.033306699999999995
metacluster_0/pattern_130.00249508
Pattern NameHomerSignificance
motif12.motif0.016169299999999998
Sp3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000300454
metacluster_0/pattern_21.7552900000000003e-06
metacluster_0/pattern_30.00455855
metacluster_0/pattern_40.00122553
metacluster_0/pattern_53.27006e-07
metacluster_0/pattern_130.0157173
metacluster_0/pattern_150.0009649319999999999
Pattern NameHomerSignificance
motif1.motif0.00241666
Klf6
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00558393
metacluster_0/pattern_20.00125238
metacluster_0/pattern_50.00249864
Pattern NameHomerSignificance
motif1.motif0.0024229
Ehf
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00398763
Pattern NameHomerSignificance
motif6.motif0.0191838
Ets1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00066518
Pattern NameHomerSignificance
motif6.motif0.0078124
Rfx2
Pattern NameModiscoSignificance
metacluster_0/pattern_101.66391e-07
Pattern NameHomerSignificance
motif7.motif0.001347
Gabpa
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000555453
Pattern NameHomerSignificance
motif6.motif0.00721875
E2f4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00642519
metacluster_0/pattern_20.000629446
Pattern NameHomerSignificance
motif1.motif0.0112774
Etv3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00155166
Pattern NameHomerSignificance
motif6.motif0.0078124
Klf3
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0005005459999999999
metacluster_0/pattern_21.3721600000000001e-05
metacluster_0/pattern_30.020687599999999997
metacluster_0/pattern_40.044097199999999996
metacluster_0/pattern_51.1359200000000001e-05
metacluster_0/pattern_150.0179894
metacluster_0/pattern_240.0386126
Pattern NameHomerSignificance
motif1.motif0.00154006
Gli2
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0386126
Pattern NameHomerSignificance
motif21.motif0.056205399999999996
Klf5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0554235
metacluster_0/pattern_28.44641e-05
metacluster_0/pattern_50.00272083
Pattern NameHomerSignificance
motif1.motif0.015777600000000003
Elf4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000589553
Pattern NameHomerSignificance
motif6.motif0.00767232
Atf2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.017999599999999998
metacluster_0/pattern_130.00249508
Pattern NameHomerSignificance
motif12.motif0.0191254
Tbx2
Pattern NameModiscoSignificance
metacluster_0/pattern_118.71606e-13
Pattern NameHomerSignificance
motif4.motif1.17279e-05
Zfp143
Pattern NameModiscoSignificance
metacluster_0/pattern_114.54406e-19
Pattern NameHomerSignificance
motif4.motif1.53458e-07
Elf1
Pattern NameModiscoSignificance
metacluster_0/pattern_71.41306e-06
Pattern NameHomerSignificance
motif6.motif0.00455773
Klf7
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00889918
metacluster_0/pattern_28.060390000000001e-05
Pattern NameHomerSignificance
motif1.motif0.00195456
Klf1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.010442
metacluster_0/pattern_20.0232201
metacluster_0/pattern_50.0194038
Pattern NameHomerSignificance
motif1.motif0.0069001
Klf8
Pattern NameModiscoSignificance
metacluster_0/pattern_00.010162000000000001
metacluster_0/pattern_20.00011768899999999999
Pattern NameHomerSignificance
motif1.motif0.00241666
Sp4
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0162657
metacluster_0/pattern_20.0007349289999999999
metacluster_0/pattern_50.028930900000000002
Pattern NameHomerSignificance
motif1.motif0.0492344
Nfyc
Pattern NameModiscoSignificance
metacluster_0/pattern_14.37495e-11
Pattern NameHomerSignificance
motif2.motif1.20395e-09
Elk4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000555453
Pattern NameHomerSignificance
motif6.motif0.00767232
Foxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_17.698569999999999e-07
Pattern NameHomerSignificance
motif2.motif1.78598e-05
Spi1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.036104699999999997
Pattern NameHomerSignificance
motif6.motif0.0464211
Rfx7
Pattern NameModiscoSignificance
metacluster_0/pattern_100.00489758
Pattern NameHomerSignificance
motif7.motif0.04693680000000001
Rfx6
Pattern NameModiscoSignificance
metacluster_0/pattern_80.00201112
metacluster_0/pattern_100.00162886
Pattern NameHomerSignificance
motif7.motif0.04693680000000001
Elk3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000271044
Pattern NameHomerSignificance
motif6.motif0.00721875
Elf3
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0229012
Pattern NameHomerSignificance
motif6.motif0.0436376
Atf1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0473042
metacluster_0/pattern_130.013306799999999999
Pattern NameHomerSignificance
motif12.motif0.0267807
Nrf1
Pattern NameModiscoSignificance
metacluster_0/pattern_37.40317e-06
Pattern NameHomerSignificance
motif3.motif1.5882e-05
Erg
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000589553
Pattern NameHomerSignificance
motif6.motif0.0078124
Atf7
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0163495
metacluster_0/pattern_130.00101496
Pattern NameHomerSignificance
motif12.motif0.0183498
Sp5
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00758559
metacluster_0/pattern_26.7288e-08
metacluster_0/pattern_50.028205
metacluster_0/pattern_240.00685763
Pattern NameHomerSignificance
motif1.motif0.030364
Elf5
Pattern NameModiscoSignificance
metacluster_0/pattern_70.013831200000000002
Pattern NameHomerSignificance
motif6.motif0.012123700000000001
Nfyb
Pattern NameModiscoSignificance
metacluster_0/pattern_12.67768e-12
Pattern NameHomerSignificance
motif2.motif5.857909999999999e-10
Egr1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00832272
metacluster_0/pattern_20.054707000000000006
Pattern NameHomerSignificance
motif1.motif0.012852299999999999
Gli1
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0409777
Pattern NameHomerSignificance
motif21.motif0.056205399999999996
Klf12
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0142852
metacluster_0/pattern_20.054707000000000006
Pattern NameHomerSignificance
motif1.motif0.040035
Fli1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0466469
metacluster_0/pattern_70.00066518
Pattern NameHomerSignificance
motif6.motif0.0078124
Elf2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00113604
Pattern NameHomerSignificance
motif6.motif0.00767232
Sp2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.000300454
metacluster_0/pattern_25.781929999999999e-07
metacluster_0/pattern_36.82156e-05
metacluster_0/pattern_40.000108648
metacluster_0/pattern_53.4816199999999996e-08
metacluster_0/pattern_90.052478
metacluster_0/pattern_120.029388099999999997
metacluster_0/pattern_130.00156417
metacluster_0/pattern_155.0538e-05
metacluster_0/pattern_240.0374209
Pattern NameHomerSignificance
motif1.motif0.00241666
Zbtb17
Pattern NameModiscoSignificance
metacluster_0/pattern_00.00889918
metacluster_0/pattern_23.86123e-05
metacluster_0/pattern_50.00249864
metacluster_0/pattern_150.0210949
Pattern NameHomerSignificance
motif1.motif0.0329073
Etv1
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000567755
Pattern NameHomerSignificance
motif6.motif0.00767232
Jdp2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00190222
Pattern NameHomerSignificance
motif12.motif0.0296
Creb5
Pattern NameModiscoSignificance
metacluster_0/pattern_130.00179561
Pattern NameHomerSignificance
motif12.motif0.011814100000000001
Etv4
Pattern NameModiscoSignificance
metacluster_0/pattern_70.00967032
Pattern NameHomerSignificance
motif6.motif0.00767232
E2f1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0370556
Pattern NameHomerSignificance
motif1.motif0.0247859
Spdef
Pattern NameModiscoSignificance
metacluster_0/pattern_70.026119200000000002
Pattern NameHomerSignificance
motif6.motif0.0385652
Pbx3
Pattern NameModiscoSignificance
metacluster_0/pattern_14.82216e-06
Pattern NameHomerSignificance
motif2.motif8.48434e-05
Etv6
Pattern NameModiscoSignificance
metacluster_0/pattern_70.0488648
Pattern NameHomerSignificance
motif6.motif0.00721875
Unique TF-MoDISco TFs: #50
TF NameModiscoHomer
Fosl2
Pattern NameModiscoSignificance
metacluster_0/pattern_130.029240199999999997
Absent
Ptf1a
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0465073
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0146232
Absent
Gli3
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0282348
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0125435
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.03723680000000001
Absent
Jun
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0462079
Absent
Zfp42
Pattern NameModiscoSignificance
metacluster_0/pattern_150.00667203
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00789368
Absent
Taf1
Pattern NameModiscoSignificance
metacluster_0/pattern_154.38601e-06
Absent
Rxrg
Pattern NameModiscoSignificance
metacluster_0/pattern_90.039217400000000006
Absent
Maz
Pattern NameModiscoSignificance
metacluster_0/pattern_21.3721600000000001e-05
metacluster_0/pattern_50.036313599999999994
metacluster_0/pattern_240.00685763
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0474479
metacluster_0/pattern_40.024781400000000002
metacluster_0/pattern_50.00688997
metacluster_0/pattern_90.051167800000000006
metacluster_0/pattern_101.70573e-09
metacluster_0/pattern_130.052003999999999995
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0502151
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00785116
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0009237010000000001
Absent
Yy1
Pattern NameModiscoSignificance
metacluster_0/pattern_154.38601e-06
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0250623
metacluster_0/pattern_30.0229395
metacluster_0/pattern_40.016470699999999998
metacluster_0/pattern_50.00688997
metacluster_0/pattern_90.00134195
Absent
Max
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0241766
Absent
Bcl6
Pattern NameModiscoSignificance
metacluster_0/pattern_240.0386126
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.054707000000000006
Absent
Zbtb1
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0471364
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_0/pattern_20.00622289
metacluster_0/pattern_30.0150977
metacluster_0/pattern_40.054464599999999995
metacluster_0/pattern_50.0399588
metacluster_0/pattern_90.0241766
metacluster_0/pattern_120.029388099999999997
metacluster_0/pattern_130.0294083
metacluster_0/pattern_150.00667203
Absent
Myc
Pattern NameModiscoSignificance
metacluster_0/pattern_40.0485087
metacluster_0/pattern_90.0503272
Absent
Etv2
Pattern NameModiscoSignificance
metacluster_0/pattern_70.000555453
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0294013
metacluster_0/pattern_24.85499e-06
metacluster_0/pattern_50.00952482
metacluster_0/pattern_240.0182506
Absent
Nhlh1
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0330249
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_0/pattern_90.019663200000000002
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_0/pattern_30.0324387
metacluster_0/pattern_40.00446319
metacluster_0/pattern_50.00250827
metacluster_0/pattern_90.00789368
metacluster_0/pattern_120.0432525
metacluster_0/pattern_133.8158200000000003e-05
Absent
Rela
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0440615
metacluster_0/pattern_240.0386126
Absent
Clock
Pattern NameModiscoSignificance
metacluster_0/pattern_90.00106562
Absent
Ctcf
Pattern NameModiscoSignificance
metacluster_0/pattern_62.09801e-08
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_0/pattern_90.059068899999999994
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0575059
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_0/pattern_130.0366054
Absent
Vdr
Pattern NameModiscoSignificance
metacluster_0/pattern_260.0124796
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_0/pattern_20.0284186
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0536212
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0123929
metacluster_0/pattern_20.0378904
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_0/pattern_20.045513599999999994
Absent
Ctcfl
Pattern NameModiscoSignificance
metacluster_0/pattern_20.004996899999999999
metacluster_0/pattern_40.0282392
metacluster_0/pattern_50.00688997
metacluster_0/pattern_69.14213e-11
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_0/pattern_90.000175728
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0008051089999999999
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_0/pattern_90.016751099999999998
metacluster_0/pattern_130.011074200000000001
Absent
Srebf2
Pattern NameModiscoSignificance
metacluster_0/pattern_20.054707000000000006
metacluster_0/pattern_90.00699862
metacluster_0/pattern_130.0531284
Absent
Hic1
Pattern NameModiscoSignificance
metacluster_0/pattern_100.0557434
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0006660230000000001
Absent
Zbtb33
Pattern NameModiscoSignificance
metacluster_0/pattern_123.15639e-05
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_0/pattern_00.0256848
metacluster_0/pattern_20.054707000000000006
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_0/pattern_90.0453654
Absent
Unique Homer TFs: #1
TF NameModiscoHomer
SpibAbsent
Pattern NameHomerSignificance
motif6.motif0.0323266