# Parameters
data_name = "416B_MP;CD34+;D;GEO"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_211-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_211-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 19:28:33,680 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	myeloid progenitor cells, CD34+ (416B)
Cell Group	Cancer or Immortalized cells
Experiment Name	DHS
Experiment Group	GEO

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	193815	152251	7.4698	130295313	34323072	0.2635	13574810	0.1042	54021612	0.4147

Modelling Metadata

Metric	Value
auPRC	0.5499
Calibrated Recall at 50% FDR	0.248
Number of Positive Examples in Test Data	132851
Number of Negative Examples in Test Data	7938000
Imbalance Ratio in Test Data	0.0165
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #24

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 8021 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 5565 SequenceContrib ScoresHyp_Contrib Scores	Etv4, Erg, Etv2, Ets1, Spi1, Gabpa, Elk4, Elk1, Spib, Etv6, Fli1, Ehf, Elf2, Etv3, XP_911724.4, Elf3, Elk3, Elf4, Elf1, Etv1, Irf8, Irf4, Etv5, Spic, Elf5, Fev, Spdef, Ets2, Prdm1, Irf3, Irf2
metacluster_1/pattern_2 # seqlets: 2436 SequenceContrib ScoresHyp_Contrib Scores	Fosl1, Fosb, Atf3, Junb, Jun, Fos, Fosl2, Jund, Batf, Bach2, Jdp2, Nfe2l2, Bach1, Nfe2, Mafk, Mafa
metacluster_1/pattern_3 # seqlets: 1829 SequenceContrib ScoresHyp_Contrib Scores	Sp4, Klf3, Sp2, Sp3, Sp1, Klf6, Klf7, Klf4, E2f4, Klf8, Klf1, Klf12, Egr1, Egr2, Zbtb17, Klf5, E2f1, Sp5, Zfp281, Zbtb1, Zfp740, Egr3
metacluster_1/pattern_4 # seqlets: 1687 SequenceContrib ScoresHyp_Contrib Scores	Cebpb, Cebpd, Cebpa, Cebpg, Cebpe, Dbp, Nfil3, Hlf, Ddit3, Atf4, Tef
metacluster_1/pattern_5 # seqlets: 1398 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_6 # seqlets: 981 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_7 # seqlets: 889 SequenceContrib ScoresHyp_Contrib Scores	Nfia, Nfib
metacluster_1/pattern_8 # seqlets: 601 SequenceContrib ScoresHyp_Contrib Scores	Irf1, Irf7, Stat1, Batf3, Irf9, Stat2
metacluster_1/pattern_9 # seqlets: 591 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Foxi1, Nfyc, Nfya, Pbx3
metacluster_1/pattern_10 # seqlets: 561 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_11 # seqlets: 555 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_12 # seqlets: 496 SequenceContrib ScoresHyp_Contrib Scores	Gata4, Gata1, Gata2, Tal1, Gata6, Gata3, Gata5
metacluster_1/pattern_13 # seqlets: 393 SequenceContrib ScoresHyp_Contrib Scores	Creb1, Atf7, Atf2, Atf1, Creb5, Crem, Tfec
metacluster_1/pattern_14 # seqlets: 374 SequenceContrib ScoresHyp_Contrib Scores	Usf1, Usf2, Tfe3, Tfeb, Arntl, Mitf, Clock, Srebf1, Bhlhe40, Mlx, Arnt, Npas2, Creb3l2, Srebf2, Mycn, Tcfl5, Max, Myc, Bhlhe41, Xbp1
metacluster_1/pattern_15 # seqlets: 328 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 244 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfx, Zfp42, Rfx1
metacluster_1/pattern_17 # seqlets: 199 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_18 # seqlets: 190 SequenceContrib ScoresHyp_Contrib Scores	Six2, Six1, Six4
metacluster_1/pattern_19 # seqlets: 137 SequenceContrib ScoresHyp_Contrib Scores	Esrrb, Esrra, Nr5a2, Rara, Rarg, Rxra, Rxrg, Nr5a1, Esrrg, Nr2f6, Rxrb, Nr2c2, Rarb
metacluster_1/pattern_20 # seqlets: 113 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_21 # seqlets: 80 SequenceContrib ScoresHyp_Contrib Scores	Rest
metacluster_1/pattern_22 # seqlets: 70 SequenceContrib ScoresHyp_Contrib Scores	Mef2d, Mef2c, Mef2a
metacluster_1/pattern_23 # seqlets: 66 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33

Click here for Motifs by TF-MoDISco: #164

TF Name	Pattern(s)
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 1.89891e-13
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 6.70342e-07
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00160857
Erg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000483733
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_1 5.25641e-05
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000471726
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0029563000000000002
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00236897
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000730399
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000538665
Spib	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00021894700000000002 metacluster_1/pattern_8 0.00676284
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00084966
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000538665
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00486407
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0018489000000000001
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0005275740000000001
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000538665
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.011005899999999999
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00168362
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00111256
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0011359999999999999
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00160857
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00160857 metacluster_1/pattern_8 1.3131500000000001e-05
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00181978 metacluster_1/pattern_8 0.0541029
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00196149
Spic	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00429014
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0186581
Fev	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00543761
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_1 0.016314600000000002
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0170516
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0222445 metacluster_1/pattern_8 3.35673e-05
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0561349 metacluster_1/pattern_8 0.000319726
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0579279 metacluster_1/pattern_8 0.00200367
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06 metacluster_1/pattern_13 0.00633877
Junb	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06
Jun	Pattern Name Modisco Significance metacluster_1/pattern_2 3.5343199999999995e-06 metacluster_1/pattern_13 0.05255800000000001
Fos	Pattern Name Modisco Significance metacluster_1/pattern_2 8.07403e-06
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_2 4.09275e-05 metacluster_1/pattern_13 0.0291987
Jund	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0122491
Batf	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00267287
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00012491
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000158868 metacluster_1/pattern_13 0.00172645 metacluster_1/pattern_14 0.047824599999999995
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000428589
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00038777099999999997
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00038777099999999997
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0357356
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0357356
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00104746
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_3 2.17446e-06 metacluster_1/pattern_16 0.0516064
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_3 3.58648e-06 metacluster_1/pattern_16 3.57282e-05 metacluster_1/pattern_23 0.0009742010000000001
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_3 1.38201e-05 metacluster_1/pattern_16 0.00112434 metacluster_1/pattern_23 0.0009742010000000001
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00020747400000000003 metacluster_1/pattern_16 0.00048692099999999997 metacluster_1/pattern_23 0.000492199
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00020747400000000003
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00020747400000000003
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00692498
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00038430699999999996
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00040684900000000003
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.022415
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00500853
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.027795499999999997
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.038632
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0103636 metacluster_1/pattern_16 0.0141601
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.018444400000000003
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.018444400000000003
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.020475900000000002
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0291694
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.039052300000000005
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_3 0.05417430000000001
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.05417430000000001
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00156035
Cebpd	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00169343
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00176554
Cebpg	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00354701
Cebpe	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00384607
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_4 0.015688999999999998 metacluster_1/pattern_14 0.0521316
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0244021
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0269382 metacluster_1/pattern_14 0.0307397
Ddit3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00346472
Atf4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00346472
Tef	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0134175
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_5 4.56187e-05
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00960481
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000250025
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000511142
Gfi1b	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0564007
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_6 4.522130000000001e-08
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_7 5.6087900000000006e-06
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0140326
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_8 1.11879e-12
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00011667
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00011667
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00236096
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00265595
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00379642
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_9 3.4232199999999996e-08
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_9 3.8493699999999995e-06
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_9 6.36025e-06
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_9 8.163589999999999e-06
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00018335099999999997
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 3.80737e-21
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 5.47086e-21
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 2.8356799999999997e-14
Gata4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00206168
Gata1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.000283486
Gata2	Pattern Name Modisco Significance metacluster_1/pattern_12 2.88396e-05
Tal1	Pattern Name Modisco Significance metacluster_1/pattern_12 5.7826000000000005e-05
Gata6	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00031992
Gata3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0112804
Gata5	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0033710000000000003
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00427301 metacluster_1/pattern_14 0.053787699999999994
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_13 0.000653964 metacluster_1/pattern_14 0.0367656
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00117009
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0529909 metacluster_1/pattern_14 0.0329928
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00115462
Crem	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0227644
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0530654 metacluster_1/pattern_14 0.00241264
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00814436
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00445339
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0022379
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0006878810000000001
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00500837
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00135336
Clock	Pattern Name Modisco Significance metacluster_1/pattern_14 0.05860419999999999
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.042863599999999995
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_14 0.019756799999999998
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0139726
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00151572
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00186313
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0211581
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00665948
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_14 0.05860419999999999
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_14 0.010238500000000001
Max	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0139726
Myc	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0229417
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0292306
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0324718
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_16 9.17226e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_16 1.10701e-05
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00306661 metacluster_1/pattern_23 0.0206821
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0141601
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0338844
Six2	Pattern Name Modisco Significance metacluster_1/pattern_18 2.41952e-08
Six1	Pattern Name Modisco Significance metacluster_1/pattern_18 4.0406e-06
Six4	Pattern Name Modisco Significance metacluster_1/pattern_18 8.7294e-06
Esrrb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00212493
Esrra	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0187401
Nr5a2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000206446
Rara	Pattern Name Modisco Significance metacluster_1/pattern_19 3.41377e-05
Rarg	Pattern Name Modisco Significance metacluster_1/pattern_19 5.96395e-05
Rxra	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00748905
Rxrg	Pattern Name Modisco Significance metacluster_1/pattern_19 9.61153e-05
Nr5a1	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000210065
Esrrg	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00108844
Nr2f6	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00748905
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00748905
Nr2c2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.032618799999999996
Rarb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.05515319999999999
Rest	Pattern Name Modisco Significance metacluster_1/pattern_21 1.4250700000000001e-19
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_22 3.38342e-11
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_22 2.6429099999999997e-08
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_22 0.000528728
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_23 8.385680000000001e-07

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #102

TF Name	Modisco	Homer
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0029563000000000002	Pattern Name Homer Significance motif2.motif 0.009707799999999999
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000471726	Pattern Name Homer Significance motif2.motif 9.76785e-07
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00115462	Pattern Name Homer Significance motif6.motif 0.014759600000000001 motif13.motif 0.0192115
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000158868 metacluster_1/pattern_13 0.00172645 metacluster_1/pattern_14 0.047824599999999995	Pattern Name Homer Significance motif3.motif 0.000174035 motif6.motif 0.016638 motif13.motif 0.0202769
Spic	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00429014	Pattern Name Homer Significance motif2.motif 0.010060600000000001
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00181978 metacluster_1/pattern_8 0.0541029	Pattern Name Homer Significance motif2.motif 0.035169900000000004
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_16 1.10701e-05	Pattern Name Homer Significance motif15.motif 4.53545e-06
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_23 8.385680000000001e-07	Pattern Name Homer Significance motif14.motif 0.000136087
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0170516	Pattern Name Homer Significance motif2.motif 0.0439615
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000538665	Pattern Name Homer Significance motif2.motif 7.20013e-05
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000250025	Pattern Name Homer Significance motif4.motif 0.00899539
Crem	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0227644	Pattern Name Homer Significance motif6.motif 0.00746599 motif13.motif 0.0257024
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 3.80737e-21	Pattern Name Homer Significance motif8.motif 8.84327e-09
Fos	Pattern Name Modisco Significance metacluster_1/pattern_2 8.07403e-06	Pattern Name Homer Significance motif3.motif 8.18217e-05
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06	Pattern Name Homer Significance motif3.motif 0.0162602 motif6.motif 0.00952796
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 6.70342e-07	Pattern Name Homer Significance motif1.motif 0.000398654 motif7.motif 0.011689299999999998
Batf	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00267287	Pattern Name Homer Significance motif3.motif 0.026408299999999996
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00156035	Pattern Name Homer Significance motif6.motif 0.000587579
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00306661 metacluster_1/pattern_23 0.0206821	Pattern Name Homer Significance motif5.motif 0.0189072
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_1 0.016314600000000002	Pattern Name Homer Significance motif2.motif 0.00622369
Junb	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06	Pattern Name Homer Significance motif3.motif 0.0150483
Jun	Pattern Name Modisco Significance metacluster_1/pattern_2 3.5343199999999995e-06 metacluster_1/pattern_13 0.05255800000000001	Pattern Name Homer Significance motif3.motif 0.0329642 motif6.motif 0.0140684
Cebpd	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00169343	Pattern Name Homer Significance motif6.motif 0.000587579
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0244021	Pattern Name Homer Significance motif6.motif 0.015512399999999999
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000538665	Pattern Name Homer Significance motif2.motif 0.000603582
Ddit3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00346472	Pattern Name Homer Significance motif6.motif 0.059041199999999995
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00038430699999999996	Pattern Name Homer Significance motif5.motif 0.00417648
Gata5	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0033710000000000003	Pattern Name Homer Significance motif12.motif 0.015570600000000002
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_2 4.09275e-05 metacluster_1/pattern_13 0.0291987	Pattern Name Homer Significance motif3.motif 9.69513e-05 motif6.motif 0.047407300000000006
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00160857 metacluster_1/pattern_8 1.3131500000000001e-05	Pattern Name Homer Significance motif2.motif 0.0328382
Tef	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0134175	Pattern Name Homer Significance motif6.motif 0.00032658
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00084966	Pattern Name Homer Significance motif2.motif 4.3127399999999996e-05
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000511142	Pattern Name Homer Significance motif4.motif 0.00694387
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00692498	Pattern Name Homer Significance motif5.motif 0.000806326
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0011359999999999999	Pattern Name Homer Significance motif2.motif 0.015242799999999999
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0018489000000000001	Pattern Name Homer Significance motif2.motif 0.00192304
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.027795499999999997	Pattern Name Homer Significance motif5.motif 0.030751900000000002
Spib	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00021894700000000002 metacluster_1/pattern_8 0.00676284	Pattern Name Homer Significance motif2.motif 0.0121874
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00038777099999999997	Pattern Name Homer Significance motif3.motif 0.0007816310000000001
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00160857	Pattern Name Homer Significance motif2.motif 1.12588e-06
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00236897	Pattern Name Homer Significance motif2.motif 0.00927319
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00486407	Pattern Name Homer Significance motif2.motif 0.017627900000000002
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_9 8.163589999999999e-06	Pattern Name Homer Significance motif11.motif 5.6603199999999995e-06
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_16 9.17226e-06	Pattern Name Homer Significance motif15.motif 0.000992216
Gata2	Pattern Name Modisco Significance metacluster_1/pattern_12 2.88396e-05	Pattern Name Homer Significance motif12.motif 0.0154953
Gata4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00206168	Pattern Name Homer Significance motif12.motif 0.015570600000000002
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000538665	Pattern Name Homer Significance motif2.motif 1.7476900000000002e-05
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0357356	Pattern Name Homer Significance motif3.motif 0.00949114
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00018335099999999997	Pattern Name Homer Significance motif11.motif 0.00125764
Cebpg	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00354701	Pattern Name Homer Significance motif6.motif 0.00115319
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06	Pattern Name Homer Significance motif3.motif 0.000357877
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0529909 metacluster_1/pattern_14 0.0329928	Pattern Name Homer Significance motif6.motif 0.0536806 motif13.motif 0.0584511
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 1.89891e-13	Pattern Name Homer Significance motif1.motif 1.2970999999999998e-05 motif7.motif 0.011689299999999998
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00196149	Pattern Name Homer Significance motif2.motif 1.1496800000000001e-05
Cebpe	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00384607	Pattern Name Homer Significance motif6.motif 0.000587579
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_1 5.25641e-05	Pattern Name Homer Significance motif2.motif 9.76785e-07
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 5.47086e-21	Pattern Name Homer Significance motif8.motif 1.29085e-07
Fev	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00543761	Pattern Name Homer Significance motif2.motif 0.00315861
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_3 2.17446e-06 metacluster_1/pattern_16 0.0516064	Pattern Name Homer Significance motif5.motif 0.0007611489999999999
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00111256	Pattern Name Homer Significance motif2.motif 0.000849171
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00038777099999999997	Pattern Name Homer Significance motif3.motif 0.00089389
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_9 6.36025e-06	Pattern Name Homer Significance motif11.motif 8.1838e-06
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 2.8356799999999997e-14	Pattern Name Homer Significance motif8.motif 1.89532e-06
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00104746	Pattern Name Homer Significance motif5.motif 0.00078676
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_6 4.522130000000001e-08	Pattern Name Homer Significance motif9.motif 1.69056e-06
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00176554	Pattern Name Homer Significance motif6.motif 0.00111662
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0141601	Pattern Name Homer Significance motif15.motif 0.00195832
Atf4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00346472	Pattern Name Homer Significance motif6.motif 0.0596342
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00020747400000000003	Pattern Name Homer Significance motif5.motif 0.0024229
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.022415	Pattern Name Homer Significance motif5.motif 0.0377662
Gata1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.000283486	Pattern Name Homer Significance motif12.motif 0.037240800000000004
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00960481	Pattern Name Homer Significance motif4.motif 0.0151651
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.011005899999999999	Pattern Name Homer Significance motif2.motif 0.0234106
Gata3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0112804	Pattern Name Homer Significance motif12.motif 0.052749000000000004
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00500853	Pattern Name Homer Significance motif5.motif 0.014747799999999998
Erg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000483733	Pattern Name Homer Significance motif2.motif 9.76785e-07
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0269382 metacluster_1/pattern_14 0.0307397	Pattern Name Homer Significance motif6.motif 0.0061131
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0005275740000000001	Pattern Name Homer Significance motif2.motif 1.1496800000000001e-05
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0186581	Pattern Name Homer Significance motif2.motif 0.00782479
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000428589	Pattern Name Homer Significance motif3.motif 0.00089389
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_3 3.58648e-06 metacluster_1/pattern_16 3.57282e-05 metacluster_1/pattern_23 0.0009742010000000001	Pattern Name Homer Significance motif5.motif 0.000598908
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_2 3.52904e-06 metacluster_1/pattern_13 0.00633877	Pattern Name Homer Significance motif3.motif 0.00041692199999999996 motif6.motif 0.0596342
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_9 3.4232199999999996e-08	Pattern Name Homer Significance motif11.motif 6.10204e-07
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00168362	Pattern Name Homer Significance motif2.motif 0.000927025
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00012491	Pattern Name Homer Significance motif3.motif 0.00041692199999999996
Tal1	Pattern Name Modisco Significance metacluster_1/pattern_12 5.7826000000000005e-05	Pattern Name Homer Significance motif12.motif 0.0221093
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00427301 metacluster_1/pattern_14 0.053787699999999994	Pattern Name Homer Significance motif6.motif 0.017446 motif13.motif 0.0313822
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.018444400000000003	Pattern Name Homer Significance motif5.motif 0.0236123
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00020747400000000003	Pattern Name Homer Significance motif5.motif 0.00340015
Gata6	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00031992	Pattern Name Homer Significance motif12.motif 0.0154953
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00020747400000000003 metacluster_1/pattern_16 0.00048692099999999997 metacluster_1/pattern_23 0.000492199	Pattern Name Homer Significance motif5.motif 0.00340015
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00040684900000000003	Pattern Name Homer Significance motif5.motif 0.00340015
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000730399	Pattern Name Homer Significance motif2.motif 7.17529e-06
Jund	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0122491	Pattern Name Homer Significance motif3.motif 0.00531703
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0357356	Pattern Name Homer Significance motif3.motif 0.00677785
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_13 0.000653964 metacluster_1/pattern_14 0.0367656	Pattern Name Homer Significance motif6.motif 0.00746599 motif13.motif 0.041132199999999994
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00160857	Pattern Name Homer Significance motif2.motif 2.26732e-06
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_5 4.56187e-05	Pattern Name Homer Significance motif4.motif 0.00899539
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_9 3.8493699999999995e-06	Pattern Name Homer Significance motif11.motif 0.00162302
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00117009	Pattern Name Homer Significance motif6.motif 0.03995 motif13.motif 0.041132199999999994
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_3 1.38201e-05 metacluster_1/pattern_16 0.00112434 metacluster_1/pattern_23 0.0009742010000000001	Pattern Name Homer Significance motif5.motif 0.0007611489999999999
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_4 0.015688999999999998 metacluster_1/pattern_14 0.0521316	Pattern Name Homer Significance motif6.motif 0.0102708

Unique TF-MoDISco TFs: #62

TF Name	Modisco	Homer
Nr2f6	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00748905	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0338844	Absent
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00379642	Absent
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00151572	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00186313	Absent
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0579279 metacluster_1/pattern_8 0.00200367	Absent
Esrrg	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00108844	Absent
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_22 0.000528728	Absent
Six2	Pattern Name Modisco Significance metacluster_1/pattern_18 2.41952e-08	Absent
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.05417430000000001	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0139726	Absent
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00814436	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_14 0.05860419999999999	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.042863599999999995	Absent
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.018444400000000003	Absent
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.020475900000000002	Absent
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0022379	Absent
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_8 1.11879e-12	Absent
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0140326	Absent
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0103636 metacluster_1/pattern_16 0.0141601	Absent
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00265595	Absent
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00500837	Absent
Rxrg	Pattern Name Modisco Significance metacluster_1/pattern_19 9.61153e-05	Absent
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_3 0.05417430000000001	Absent
Rxra	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00748905	Absent
Rarb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.05515319999999999	Absent
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_14 0.05860419999999999	Absent
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0222445 metacluster_1/pattern_8 3.35673e-05	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0292306	Absent
Six4	Pattern Name Modisco Significance metacluster_1/pattern_18 8.7294e-06	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00665948	Absent
Rarg	Pattern Name Modisco Significance metacluster_1/pattern_19 5.96395e-05	Absent
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.038632	Absent
Nr5a1	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000210065	Absent
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_22 2.6429099999999997e-08	Absent
Myc	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0229417	Absent
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_22 3.38342e-11	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_7 5.6087900000000006e-06	Absent
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0211581	Absent
Esrrb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00212493	Absent
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.039052300000000005	Absent
Gfi1b	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0564007	Absent
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00236096	Absent
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0561349 metacluster_1/pattern_8 0.000319726	Absent
Esrra	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0187401	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_14 0.010238500000000001	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0006878810000000001	Absent
Nr5a2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000206446	Absent
Rest	Pattern Name Modisco Significance metacluster_1/pattern_21 1.4250700000000001e-19	Absent
Rara	Pattern Name Modisco Significance metacluster_1/pattern_19 3.41377e-05	Absent
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0291694	Absent
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00011667	Absent
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00135336	Absent
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00445339	Absent
Max	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0139726	Absent
Nr2c2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.032618799999999996	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0530654 metacluster_1/pattern_14 0.00241264	Absent
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00011667	Absent
Six1	Pattern Name Modisco Significance metacluster_1/pattern_18 4.0406e-06	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_14 0.019756799999999998	Absent
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0324718	Absent
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00748905	Absent

Unique Homer TFs: #7

TF Name	Modisco	Homer
Gmeb1	Absent	Pattern Name Homer Significance motif6.motif 0.0482925
Maf	Absent	Pattern Name Homer Significance motif3.motif 0.023221900000000004
Mypop	Absent	Pattern Name Homer Significance motif6.motif 0.017349200000000002
Mafg	Absent	Pattern Name Homer Significance motif3.motif 0.0161707
Mafb	Absent	Pattern Name Homer Significance motif3.motif 0.0162602
Gmeb2	Absent	Pattern Name Homer Significance motif6.motif 0.00951435
Maff	Absent	Pattern Name Homer Significance motif3.motif 0.025294999999999998