In [1]:
# Parameters
data_name = "aB_LPS+IL21;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_15-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_15-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 18:44:08,351 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeaB LPS+IL21
    Cell GroupB cells
    Experiment NameATAC
    Experiment GroupCasellas Lab
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1431022878013.7624573474938315170.083842268700.0925144054500.3151
    Modelling Metadata
    MetricValue
    auPRC0.7158
    Calibrated Recall at 50% FDR0.175
    Number of Positive Examples in Test Data37148
    Number of Negative Examples in Test Data8033703
    Imbalance Ratio in Test Data0.0046
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #18
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 6794 SequenceContrib ScoresHyp_Contrib Scores
Sp1, Sp2, Spib, Spi1, Sp3, Irf8, Irf4, Erg, Maz, Wt1,

Klf3, Sp4, Sp5, Etv4, Ets1, Etv2, Klf15, Etv6, Zfx, Rela, Elk1,

Irf2, Zbtb17, Ehf, Elf3, Etv3, Fli1, Spic, Gabpa, Klf6, XP_911724.4, Elf4,

Elk4, Prdm1, Irf1, Elk3, Elf2, Elf1, Etv1, Elf5, Etv5, Irf3, Zfp281,

Fev, Zscan10, Tcf7, Usf2, Ets2, Ctcfl, Bcl6, Nr1d2, Mxi1, E2f3, Ptf1a,

Spdef, Mecp2, Klf4, Nr1h4
metacluster_1/pattern_1 # seqlets: 4226 SequenceContrib ScoresHyp_Contrib Scores
Ctcf
metacluster_1/pattern_2 # seqlets: 3770 SequenceContrib ScoresHyp_Contrib Scores
E2f4, Klf7, Egr1, Klf8, Klf12, Klf5, Egr2, Klf1, E2f1, Egr3,

Srebf2, Zbtb1, Zfp740
metacluster_1/pattern_3 # seqlets: 1766 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_4 # seqlets: 1724 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1349 SequenceContrib ScoresHyp_Contrib Scores
Yy1, Taf1, Rfx1, Zfp42
metacluster_1/pattern_6 # seqlets: 1194 SequenceContrib ScoresHyp_Contrib Scores
Stat1, Stat2, Irf7, Irf9, Irf5
metacluster_1/pattern_7 # seqlets: 1039 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_8 # seqlets: 796 SequenceContrib ScoresHyp_Contrib Scores
Creb1, Atf2, Atf7, Atf1, Jdp2, Crem, Creb5, Atf3, Fosl2, Fosl1,

Jun, Nfil3, Rxrb, Tef, Hlf
metacluster_1/pattern_9 # seqlets: 619 SequenceContrib ScoresHyp_Contrib Scores
Pou2f2, Pou2f1
metacluster_1/pattern_10 # seqlets: 567 SequenceContrib ScoresHyp_Contrib Scores
Tfec, Tfeb, Usf1, Mitf, Arntl, Bhlhe40, Srebf1, Tfe3, Mlx, Arnt,

Clock, Npas2, Tcfl5, Bhlhe41, Creb3l2, Dbp, Mlxip, Arnt2
metacluster_1/pattern_11 # seqlets: 303 SequenceContrib ScoresHyp_Contrib Scores
Nfkb1, Nfkb2, Relb, Rel
metacluster_1/pattern_12 # seqlets: 231 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_13 # seqlets: 228 SequenceContrib ScoresHyp_Contrib Scores
Fos, Jund, Fosb, Batf, Junb, Bach2, Nfe2, Nfe2l2, Bach1, Mafa,

Mafk
metacluster_1/pattern_14 # seqlets: 181 SequenceContrib ScoresHyp_Contrib Scores
Ebf1, Prdm16
metacluster_1/pattern_15 # seqlets: 119 SequenceContrib ScoresHyp_Contrib Scores
Mef2d, Mef2a, Mef2c
metacluster_1/pattern_16 # seqlets: 115 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_17 # seqlets: 40 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib
Click here for Motifs by TF-MoDISco: #148
TF NamePattern(s)
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_09.920820000000001e-07
metacluster_1/pattern_20.00041504599999999997
metacluster_1/pattern_120.00467111
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_09.920820000000001e-07
metacluster_1/pattern_27.38464e-08
metacluster_1/pattern_50.0309335
metacluster_1/pattern_120.000237253
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_09.920820000000001e-07
metacluster_1/pattern_60.00910848
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00113837
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_01.0793800000000002e-05
metacluster_1/pattern_22.36973e-07
metacluster_1/pattern_120.00146792
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_05.60042e-05
metacluster_1/pattern_62.0507e-06
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_08.401989999999999e-05
metacluster_1/pattern_60.00290383
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00175792
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000239161
metacluster_1/pattern_20.0105635
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000360731
metacluster_1/pattern_20.00234636
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00037596300000000005
metacluster_1/pattern_25.46083e-07
metacluster_1/pattern_120.047051300000000004
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000490309
metacluster_1/pattern_20.00132993
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0006702810000000001
metacluster_1/pattern_20.000845473
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00621118
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00141748
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00105715
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00105715
metacluster_1/pattern_20.028258099999999994
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00175792
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00439218
metacluster_1/pattern_30.0338283
metacluster_1/pattern_120.00146792
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00116949
metacluster_1/pattern_117.12459e-05
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00223508
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00122936
metacluster_1/pattern_60.00846233
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00130931
metacluster_1/pattern_20.000845473
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0119469
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0170673
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00175792
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00263615
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00291224
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00835518
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00261307
metacluster_1/pattern_20.000520042
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0026296999999999996
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00291224
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00693232
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00422002
metacluster_1/pattern_60.00091878
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00438827
metacluster_1/pattern_61.02525e-06
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00745321
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.011131100000000001
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00527457
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00745321
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0145671
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00623201
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00769224
metacluster_1/pattern_60.044577099999999995
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_00.012467
metacluster_1/pattern_20.00473041
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.012736
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0145671
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0159238
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0168868
metacluster_1/pattern_84.06934e-05
metacluster_1/pattern_100.00910313
metacluster_1/pattern_120.037411599999999996
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.023244
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_00.029002899999999998
metacluster_1/pattern_11.82485e-08
Bcl6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0307262
Nr1d2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.03595
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.036812199999999996
E2f3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0370225
Ptf1a
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0388841
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.04890030000000001
Mecp2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0484213
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05665359999999999
metacluster_1/pattern_20.000845473
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05665359999999999
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_14.14467e-11
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00030330099999999996
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000658862
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.015227100000000002
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00110067
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.054369299999999995
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00119314
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.036615800000000004
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0187716
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.020977700000000002
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.040598300000000004
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0503318
metacluster_1/pattern_100.00262061
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.056662199999999996
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.056662199999999996
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_34.3563999999999995e-07
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_41.1387399999999999e-10
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_45.332330000000001e-06
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_45.858730000000001e-06
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_47.94836e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000124941
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.3386099999999999e-05
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.3386099999999999e-05
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00324993
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0344346
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0008566110000000001
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00091878
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00091878
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00351808
Irf5
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0191292
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_76.14231e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_78.75902e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_72.31917e-13
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00223407
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000532915
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000206971
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0490894
metacluster_1/pattern_100.015425999999999999
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000592824
metacluster_1/pattern_136.20104e-05
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00590833
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00113728
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00355833
metacluster_1/pattern_130.000112356
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00896772
metacluster_1/pattern_130.000122247
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.018635
metacluster_1/pattern_130.0379648
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0256292
metacluster_1/pattern_130.035263800000000005
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0265788
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.043868
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0490894
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.055789599999999995
metacluster_1/pattern_100.041827300000000005
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0111015
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05813530000000001
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00563992
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00207519
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0060238
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00411866
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0114164
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00384841
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0025756
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0060238
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_100.048025599999999995
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0370779
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_100.04838219999999999
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00260217
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00441826
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00832318
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0215738
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0487192
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0559956
Arnt2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0568584
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_111.63107e-05
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_117.12459e-05
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_117.12459e-05
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00191068
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_125.74564e-05
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_136.20104e-05
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00438743
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_137.10651e-05
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00463732
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0410759
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00428375
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00482072
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00650863
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00666467
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_130.043748300000000004
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_130.052351800000000004
Ebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.005044
Prdm16
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00415832
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_153.10247e-11
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_150.000277163
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_151.27934e-07
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000588665
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000588665
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #90
TF NameModiscoHomer
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_41.1387399999999999e-10
Pattern NameHomerSignificance
motif4.motif8.451789999999999e-07
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00105715
Pattern NameHomerSignificance
motif3.motif0.00176182
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.056662199999999996
Pattern NameHomerSignificance
motif1.motif0.052827
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0060238
Pattern NameHomerSignificance
motif7.motif0.0243766
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0145671
Pattern NameHomerSignificance
motif3.motif0.00146323
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00263615
Pattern NameHomerSignificance
motif3.motif0.000590128
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_00.012736
Pattern NameHomerSignificance
motif3.motif0.00832562
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.3386099999999999e-05
Pattern NameHomerSignificance
motif10.motif0.0005177609999999999
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00291224
Pattern NameHomerSignificance
motif3.motif9.50735e-05
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_45.332330000000001e-06
Pattern NameHomerSignificance
motif4.motif3.37937e-05
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00110067
Pattern NameHomerSignificance
motif1.motif0.0008425
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00261307
metacluster_1/pattern_20.000520042
Pattern NameHomerSignificance
motif1.motif0.00302486
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.043868
Pattern NameHomerSignificance
motif7.motif0.0241525
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00223508
Pattern NameHomerSignificance
motif3.motif0.000359775
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_09.920820000000001e-07
metacluster_1/pattern_60.00910848
Pattern NameHomerSignificance
motif3.motif0.0189261
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00527457
Pattern NameHomerSignificance
motif3.motif0.00044659
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0114164
Pattern NameHomerSignificance
motif7.motif0.0243766
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_47.94836e-06
Pattern NameHomerSignificance
motif4.motif0.00270732
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0170673
Pattern NameHomerSignificance
motif3.motif0.028391800000000002
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_40.000124941
Pattern NameHomerSignificance
motif4.motif0.0006084290000000001
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_01.0793800000000002e-05
metacluster_1/pattern_22.36973e-07
metacluster_1/pattern_120.00146792
Pattern NameHomerSignificance
motif1.motif0.00144182
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00590833
Pattern NameHomerSignificance
motif7.motif0.0534716
motif15.motif0.044849599999999996
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0187716
Pattern NameHomerSignificance
motif1.motif0.0436418
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000490309
metacluster_1/pattern_20.00132993
Pattern NameHomerSignificance
motif1.motif0.0229798
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00119314
Pattern NameHomerSignificance
motif1.motif0.0397595
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_78.75902e-21
Pattern NameHomerSignificance
motif5.motif3.44403e-07
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0060238
Pattern NameHomerSignificance
motif7.motif0.029244700000000002
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00835518
Pattern NameHomerSignificance
motif3.motif0.00426935
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00438743
Pattern NameHomerSignificance
motif15.motif0.049055
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_111.63107e-05
Pattern NameHomerSignificance
motif16.motif0.00230666
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_117.12459e-05
Pattern NameHomerSignificance
motif16.motif0.00897191
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00116949
metacluster_1/pattern_117.12459e-05
Pattern NameHomerSignificance
motif16.motif0.00359816
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_51.3386099999999999e-05
Pattern NameHomerSignificance
motif10.motif1.31506e-06
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_09.920820000000001e-07
metacluster_1/pattern_27.38464e-08
metacluster_1/pattern_50.0309335
metacluster_1/pattern_120.000237253
Pattern NameHomerSignificance
motif1.motif0.0006581089999999999
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0168868
metacluster_1/pattern_84.06934e-05
metacluster_1/pattern_100.00910313
metacluster_1/pattern_120.037411599999999996
Pattern NameHomerSignificance
motif7.motif0.029125599999999998
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05665359999999999
metacluster_1/pattern_20.000845473
Pattern NameHomerSignificance
motif1.motif0.0006581089999999999
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_09.920820000000001e-07
metacluster_1/pattern_20.00041504599999999997
metacluster_1/pattern_120.00467111
Pattern NameHomerSignificance
motif1.motif0.00759867
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00207519
Pattern NameHomerSignificance
motif7.motif0.0243766
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00384841
Pattern NameHomerSignificance
motif7.motif0.052760699999999994
Pou2f2
Pattern NameModiscoSignificance
metacluster_1/pattern_90.0111015
Pattern NameHomerSignificance
motif14.motif0.00544652
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00693232
Pattern NameHomerSignificance
motif3.motif0.00015493
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_34.3563999999999995e-07
Pattern NameHomerSignificance
motif6.motif0.000184875
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00175792
Pattern NameHomerSignificance
motif3.motif1.78489e-05
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00223407
Pattern NameHomerSignificance
motif7.motif0.0243766
motif15.motif0.0530492
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_45.858730000000001e-06
Pattern NameHomerSignificance
motif4.motif1.30108e-05
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00623201
Pattern NameHomerSignificance
motif3.motif2.20962e-06
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00175792
Pattern NameHomerSignificance
motif3.motif0.000303058
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_08.401989999999999e-05
metacluster_1/pattern_60.00290383
Pattern NameHomerSignificance
motif3.motif0.0528472
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00896772
metacluster_1/pattern_130.000122247
Pattern NameHomerSignificance
motif15.motif0.0194683
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00030330099999999996
Pattern NameHomerSignificance
motif1.motif0.0008425
Irf5
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0191292
Pattern NameHomerSignificance
motif3.motif0.057133
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000532915
Pattern NameHomerSignificance
motif7.motif0.0431154
motif15.motif0.0530492
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0026296999999999996
Pattern NameHomerSignificance
motif3.motif2.36496e-05
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_100.048025599999999995
Pattern NameHomerSignificance
motif7.motif0.0365457
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_100.04838219999999999
Pattern NameHomerSignificance
motif7.motif0.0365457
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_125.74564e-05
Pattern NameHomerSignificance
motif9.motif5.57018e-05
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_117.12459e-05
Pattern NameHomerSignificance
motif16.motif0.038181400000000004
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00291224
Pattern NameHomerSignificance
motif3.motif0.00484172
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00113837
Pattern NameHomerSignificance
motif3.motif0.0312095
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0410759
Pattern NameHomerSignificance
motif15.motif0.05838009999999999
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.018635
metacluster_1/pattern_130.0379648
Pattern NameHomerSignificance
motif15.motif0.0177322
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_72.31917e-13
Pattern NameHomerSignificance
motif5.motif5.940899999999999e-05
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000206971
Pattern NameHomerSignificance
motif7.motif0.0365457
motif15.motif0.0557476
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00175792
Pattern NameHomerSignificance
motif3.motif0.00426935
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00113728
Pattern NameHomerSignificance
motif7.motif0.0243766
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000658862
Pattern NameHomerSignificance
motif1.motif0.0006581089999999999
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.054369299999999995
Pattern NameHomerSignificance
motif1.motif0.014349299999999999
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00745321
Pattern NameHomerSignificance
motif3.motif3.39044e-05
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0119469
Pattern NameHomerSignificance
motif3.motif0.0150289
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_00.029002899999999998
metacluster_1/pattern_11.82485e-08
Pattern NameHomerSignificance
motif2.motif1.9468e-05
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00351808
Pattern NameHomerSignificance
motif12.motif0.0236972
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00141748
Pattern NameHomerSignificance
motif3.motif0.000359775
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.015227100000000002
Pattern NameHomerSignificance
motif1.motif0.030621299999999997
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00411866
Pattern NameHomerSignificance
motif7.motif0.0365457
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.011131100000000001
Pattern NameHomerSignificance
motif3.motif0.0104591
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00355833
metacluster_1/pattern_130.000112356
Pattern NameHomerSignificance
motif7.motif0.0534716
motif15.motif0.0530492
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0490894
metacluster_1/pattern_100.015425999999999999
Pattern NameHomerSignificance
motif7.motif0.052760699999999994
motif15.motif0.0530492
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00037596300000000005
metacluster_1/pattern_25.46083e-07
metacluster_1/pattern_120.047051300000000004
Pattern NameHomerSignificance
motif1.motif0.0006581089999999999
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00621118
Pattern NameHomerSignificance
motif3.motif0.00187537
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0503318
metacluster_1/pattern_100.00262061
Pattern NameHomerSignificance
motif7.motif0.029244700000000002
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_50.0344346
Pattern NameHomerSignificance
motif10.motif0.00429962
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0025756
Pattern NameHomerSignificance
motif7.motif0.047663599999999993
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_05.60042e-05
metacluster_1/pattern_62.0507e-06
Pattern NameHomerSignificance
motif3.motif0.0530762
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000592824
metacluster_1/pattern_136.20104e-05
Pattern NameHomerSignificance
motif7.motif0.0338091
motif15.motif0.00999566
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00563992
Pattern NameHomerSignificance
motif7.motif0.0243766
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00745321
Pattern NameHomerSignificance
motif3.motif0.000359775
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_00.04890030000000001
Pattern NameHomerSignificance
motif3.motif0.00919782
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_76.14231e-21
Pattern NameHomerSignificance
motif5.motif3.44403e-07
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_14.14467e-11
Pattern NameHomerSignificance
motif2.motif1.34612e-06
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0256292
metacluster_1/pattern_130.035263800000000005
Pattern NameHomerSignificance
motif15.motif0.013034
Unique TF-MoDISco TFs: #58
TF NameModiscoHomer
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00438827
metacluster_1/pattern_61.02525e-06
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00091878
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.040598300000000004
Absent
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0159238
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0490894
Absent
E2f3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0370225
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00666467
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0006702810000000001
metacluster_1/pattern_20.000845473
Absent
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00122936
metacluster_1/pattern_60.00846233
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0487192
Absent
Mlxip
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0559956
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000588665
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_00.012467
metacluster_1/pattern_20.00473041
Absent
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00091878
Absent
Mef2c
Pattern NameModiscoSignificance
metacluster_1/pattern_151.27934e-07
Absent
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00191068
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00769224
metacluster_1/pattern_60.044577099999999995
Absent
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00422002
metacluster_1/pattern_60.00091878
Absent
Bcl6
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0307262
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0008566110000000001
Absent
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.036615800000000004
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0370779
Absent
Nr1h4
Pattern NameModiscoSignificance
metacluster_1/pattern_00.05665359999999999
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_50.00324993
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00441826
Absent
Mxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.036812199999999996
Absent
Prdm16
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00415832
Absent
Zscan10
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0145671
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00428375
Absent
Wt1
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000360731
metacluster_1/pattern_20.00234636
Absent
Nr1d2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.03595
Absent
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00439218
metacluster_1/pattern_30.0338283
metacluster_1/pattern_120.00146792
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00832318
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_130.052351800000000004
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_137.10651e-05
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00130931
metacluster_1/pattern_20.000845473
Absent
Mecp2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0484213
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_170.000588665
Absent
Maz
Pattern NameModiscoSignificance
metacluster_1/pattern_00.000239161
metacluster_1/pattern_20.0105635
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.056662199999999996
Absent
Arnt2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0568584
Absent
Pou2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_90.05813530000000001
Absent
Ptf1a
Pattern NameModiscoSignificance
metacluster_1/pattern_00.0388841
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00650863
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.0215738
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.020977700000000002
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.055789599999999995
metacluster_1/pattern_100.041827300000000005
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_136.20104e-05
Absent
Mef2a
Pattern NameModiscoSignificance
metacluster_1/pattern_150.000277163
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00482072
Absent
Mef2d
Pattern NameModiscoSignificance
metacluster_1/pattern_153.10247e-11
Absent
Ebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_140.005044
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_100.00260217
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_130.043748300000000004
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00463732
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_00.023244
Absent
Klf15
Pattern NameModiscoSignificance
metacluster_1/pattern_00.00105715
metacluster_1/pattern_20.028258099999999994
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0265788
Absent
Unique Homer TFs: #10
TF NameModiscoHomer
CebpdAbsent
Pattern NameHomerSignificance
motif15.motif0.0557476
CebpaAbsent
Pattern NameHomerSignificance
motif15.motif0.05838009999999999
Zic3Absent
Pattern NameHomerSignificance
motif2.motif0.054071400000000006
CebpbAbsent
Pattern NameHomerSignificance
motif15.motif0.05838009999999999
Zic2Absent
Pattern NameHomerSignificance
motif2.motif0.0530868
Atf4Absent
Pattern NameHomerSignificance
motif15.motif0.0530492
CebpeAbsent
Pattern NameHomerSignificance
motif15.motif0.0557476
CebpgAbsent
Pattern NameHomerSignificance
motif15.motif0.0564212
Ddit3Absent
Pattern NameHomerSignificance
motif15.motif0.0530492
Xbp1Absent
Pattern NameHomerSignificance
motif7.motif0.050963699999999994