In [1]:
# Parameters
data_name = "apCD4Eff;D;GEO"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_208-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_208-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"
In [2]:
from matlas.reports import display_metadata
load data from labcluster
Using TensorFlow backend.
2019-08-30 19:28:13,634 [WARNING] git-lfs not installed
In [3]:
display_metadata(data_name, perf_file, reportfile, sheetname)
    Sample Information
    MetaData NameDescription
    Cell typeActivated primary CD4 effector cells, isolated ex vivo
    Cell GroupT cells
    Experiment NameDHS
    Experiment GroupGEO
    Pipeline Output
    replicateNaïve overlap peaksIDR peaksTSS enrichment (< 8 is very poor <10 is low)Final number of unique mapping, dup-filtered, chrM filtered readsNumber of reads in called peak regionsFraction of reads in called peak regionsNumber of reads in promoter regionsFraction of reads in promoter regionsNumber of reads in enhancer regionsFraction of reads in enhancer regions
    rep1979527617510.57689807626192570610.2145129278770.144324359290.3612
    Modelling Metadata
    MetricValue
    auPRC0.6148
    Calibrated Recall at 50% FDR0.211
    Number of Positive Examples in Test Data91698
    Number of Negative Examples in Test Data7979153
    Imbalance Ratio in Test Data0.0114
    Test Chromosomeschr2, chr3, chr19
In [4]:
from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns
In [5]:
display_denovo_patterns(data_name, modisco_root=modisco_root)
TF-MoDISco is using the TensorFlow backend.
The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco
Click here for Denovo Patterns by TF-MoDISco: #23
Pattern NameTF Name(s)Modisco
metacluster_1/pattern_0 # seqlets: 5826 SequenceContrib ScoresHyp_Contrib Scores
Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4940 SequenceContrib ScoresHyp_Contrib Scores
Erg, Ets1, Elk1, Gabpa, Fli1, Elk4, Etv2, Etv4, Etv5, Elk3,

Elf2, Spi1, Etv6, Elf1, Ehf, Fev, Etv3, Etv1, XP_911724.4, Spib, Elf3,

Elf4, Elf5, Stat4, Irf8, Irf4, Ets2, Spdef, Spic
metacluster_1/pattern_2 # seqlets: 4538 SequenceContrib ScoresHyp_Contrib Scores
Sp4, Sp2, Klf3, Sp3, Sp1, Klf4, Klf7, E2f4, Klf6, Klf1,

Klf8, Klf12, Egr1, Egr2, Zbtb17, Klf5, E2f1, Zfp281, Sp5, Zfp740, Egr3,

Zfx, Zbtb1, Sall4
metacluster_1/pattern_3 # seqlets: 1427 SequenceContrib ScoresHyp_Contrib Scores
Irf1, Irf2, Stat1, Irf7, Prdm1, Stat2, Irf3, Irf9, Batf3
metacluster_1/pattern_4 # seqlets: 1221 SequenceContrib ScoresHyp_Contrib Scores
Nrf1
metacluster_1/pattern_5 # seqlets: 1174 SequenceContrib ScoresHyp_Contrib Scores
Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_6 # seqlets: 848 SequenceContrib ScoresHyp_Contrib Scores
Runx1, Runx2, Runx3, Cbfb
metacluster_1/pattern_7 # seqlets: 758 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_8 # seqlets: 742 SequenceContrib ScoresHyp_Contrib Scores
Atf1, Atf7, Atf2, Creb1, Creb5, Jdp2, Crem, Mafb, Rxrb, Nfil3,

Jun, Dbp, Tfec, Hlf, Tef
metacluster_1/pattern_9 # seqlets: 649 SequenceContrib ScoresHyp_Contrib Scores
Zfp143, Thap11, Tbx2
metacluster_1/pattern_10 # seqlets: 629 SequenceContrib ScoresHyp_Contrib Scores
Taf1, Yy1, Zfp42
metacluster_1/pattern_11 # seqlets: 610 SequenceContrib ScoresHyp_Contrib Scores
Usf1, Tfe3, Tfeb, Arntl, Usf2, Mitf, Bhlhe40, Srebf1, Clock, Arnt,

Mlx, Npas2, Srebf2, Tcfl5, Creb3l2, Bhlhe41, Max, Mycn, Myc, Xbp1, Rarg
metacluster_1/pattern_12 # seqlets: 390 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_13 # seqlets: 390 SequenceContrib ScoresHyp_Contrib Scores
Jund, Batf, Fosb, Fos, Junb, Fosl2, Fosl1, Atf3, Bach2, Nfe2,

Nfe2l2, Bach1, Mafk, Mafa
metacluster_1/pattern_14 # seqlets: 384 SequenceContrib ScoresHyp_Contrib Scores
Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_15 # seqlets: 343 SequenceContrib ScoresHyp_Contrib Scores
Rfx1, Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_16 # seqlets: 269 SequenceContrib ScoresHyp_Contrib Scores
Gata3, Gata1, Gata2, Gata4, Tal1, Mecom, Gata6
metacluster_1/pattern_17 # seqlets: 132 SequenceContrib ScoresHyp_Contrib Scores
Lef1, Tcf7l2, Tcf7l1, Tcf7, Tcf3
metacluster_1/pattern_18 # seqlets: 127 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_19 # seqlets: 109 SequenceContrib ScoresHyp_Contrib Scores
Zbtb33
metacluster_1/pattern_20 # seqlets: 106 SequenceContrib ScoresHyp_Contrib Scores
Nfia, Nfib, Nfic
metacluster_1/pattern_21 # seqlets: 105 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_22 # seqlets: 98 SequenceContrib ScoresHyp_Contrib Scores
Click here for Motifs by TF-MoDISco: #157
TF NamePattern(s)
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_01.19163e-14
metacluster_1/pattern_126.90414e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_08.112589999999999e-08
metacluster_1/pattern_120.00489695
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00177964
metacluster_1/pattern_180.049253
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00177964
metacluster_1/pattern_70.0442261
metacluster_1/pattern_180.0183825
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00197479
metacluster_1/pattern_70.0495534
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00184655
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00177964
metacluster_1/pattern_180.049253
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0020678000000000003
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_13.4972100000000004e-05
metacluster_1/pattern_180.0183825
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000620979
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0121596
metacluster_1/pattern_180.0440798
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00172433
metacluster_1/pattern_180.049253
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00169055
metacluster_1/pattern_180.0374606
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0012384
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015558
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00164815
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00197479
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00216129
metacluster_1/pattern_30.00147549
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0322144
metacluster_1/pattern_180.05368969999999999
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00713031
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0408491
metacluster_1/pattern_180.0440798
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0178061
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0237626
metacluster_1/pattern_36.64035e-06
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.028145999999999997
metacluster_1/pattern_30.022150599999999996
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0284235
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.031112400000000002
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0408491
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00108278
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_23.29024e-06
metacluster_1/pattern_100.018902099999999998
metacluster_1/pattern_190.00460143
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.62387e-06
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.62387e-06
metacluster_1/pattern_190.0278197
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000307353
metacluster_1/pattern_190.031307999999999996
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00534185
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000307353
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000307353
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000350508
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.023196
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000446585
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0079119
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0240037
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0204718
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.006342800000000001
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0113119
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.013060200000000001
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0190587
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0190587
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025800999999999998
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0297163
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0367342
metacluster_1/pattern_40.0209127
metacluster_1/pattern_190.0441958
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0464527
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0561155
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.06201e-14
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00186309
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_32.33491e-05
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_35.07321e-05
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000184113
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000733015
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00123095
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00198484
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00728942
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_49.29806e-06
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_55.45173e-13
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_51.06659e-11
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_55.82256e-10
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.38151e-06
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_53.16922e-06
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00060075
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0078529
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00190161
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00378395
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026628700000000005
metacluster_1/pattern_110.021458500000000002
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00106851
metacluster_1/pattern_110.023796
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00124862
metacluster_1/pattern_110.054304899999999996
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00205641
metacluster_1/pattern_110.052365499999999995
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000628739
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00602312
metacluster_1/pattern_110.0358208
metacluster_1/pattern_133.77349e-06
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00602312
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0225033
metacluster_1/pattern_130.0593726
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0228524
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.030807599999999997
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.03434980000000001
metacluster_1/pattern_130.047850300000000005
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_80.03434980000000001
metacluster_1/pattern_110.0369053
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_80.039260699999999996
metacluster_1/pattern_110.00161745
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.041936
metacluster_1/pattern_110.023496200000000002
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0486921
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_92.5175100000000003e-21
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_92.5175100000000003e-21
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_91.91558e-13
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_102.71664e-06
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_103.929509999999999e-06
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_100.018902099999999998
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00928484
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0016954999999999997
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00034199699999999997
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00931375
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00871001
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0008571210000000001
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00669227
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.029196499999999997
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0234441
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_110.05950830000000001
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0109767
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00353966
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00382226
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00750639
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0234441
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0151535
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0222577
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_110.023796
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0369053
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0551668
Rarg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0551668
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00224014
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00671681
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00010441299999999999
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00016893599999999998
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0113558
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000527208
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.032144900000000004
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00022366400000000002
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00436624
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00635934
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00671681
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00811629
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0586818
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0441625
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_143.35488e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_143.35488e-05
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000295991
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00107875
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00396571
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_158.18746e-08
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0187509
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_151.8779699999999997e-07
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_157.963930000000001e-05
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00723346
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0278685
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.04399190000000001
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00242891
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00242891
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0119892
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0132484
Mecom
Pattern NameModiscoSignificance
metacluster_1/pattern_160.028206799999999997
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0305278
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_172.22035e-06
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00507919
metacluster_1/pattern_210.0176945
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00027949
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00778413
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00010319
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_192.43479e-05
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_201.39499e-06
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_205.3986099999999995e-05
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_200.030813599999999997
In [6]:
display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)
Number of CISBP TFs obtained by TF-MoDISco and Homer
Shared TFs between TF-MoDISco and Homer: #70
TF NameModiscoHomer
Ctcf
Pattern NameModiscoSignificance
metacluster_1/pattern_01.19163e-14
metacluster_1/pattern_126.90414e-05
Pattern NameHomerSignificance
motif1.motif0.000341735
Egr1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0240037
Pattern NameHomerSignificance
motif3.motif0.014518000000000001
Spic
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0408491
Pattern NameHomerSignificance
motif2.motif0.0295697
Elf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00713031
Pattern NameHomerSignificance
motif2.motif0.00168793
Ehf
Pattern NameModiscoSignificance
metacluster_1/pattern_10.015558
Pattern NameHomerSignificance
motif2.motif0.0295697
Thap11
Pattern NameModiscoSignificance
metacluster_1/pattern_92.5175100000000003e-21
Pattern NameHomerSignificance
motif5.motif1.50425e-05
Klf8
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000446585
Pattern NameHomerSignificance
motif3.motif0.000597242
Klf4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00534185
Pattern NameHomerSignificance
motif3.motif0.0397035
Runx2
Pattern NameModiscoSignificance
metacluster_1/pattern_60.0078529
Pattern NameHomerSignificance
motif4.motif0.00510904
Gabpa
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00184655
Pattern NameHomerSignificance
motif2.motif0.000595964
Elf3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0322144
metacluster_1/pattern_180.05368969999999999
Pattern NameHomerSignificance
motif2.motif0.0233847
Relb
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00107875
Pattern NameHomerSignificance
motif15.motif0.00312846
Elk1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00197479
metacluster_1/pattern_70.0495534
Pattern NameHomerSignificance
motif2.motif0.000259991
Irf9
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00198484
Pattern NameHomerSignificance
motif14.motif0.000234712
Klf3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.62387e-06
Pattern NameHomerSignificance
motif3.motif0.000160957
Etv1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00197479
Pattern NameHomerSignificance
motif2.motif0.00024212900000000003
Fli1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00177964
metacluster_1/pattern_180.049253
Pattern NameHomerSignificance
motif2.motif0.000225761
Spib
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00216129
metacluster_1/pattern_30.00147549
Pattern NameHomerSignificance
motif2.motif0.0354976
Etv3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Pattern NameHomerSignificance
motif2.motif0.000225761
Elk4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0020678000000000003
Pattern NameHomerSignificance
motif2.motif0.000225761
Sp2
Pattern NameModiscoSignificance
metacluster_1/pattern_23.29024e-06
metacluster_1/pattern_100.018902099999999998
metacluster_1/pattern_190.00460143
Pattern NameHomerSignificance
motif3.motif0.00019024
Sp4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.00108278
Pattern NameHomerSignificance
motif3.motif0.0343484
Cbfb
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00378395
Pattern NameHomerSignificance
motif4.motif0.00510904
Sp3
Pattern NameModiscoSignificance
metacluster_1/pattern_26.62387e-06
metacluster_1/pattern_190.0278197
Pattern NameHomerSignificance
motif3.motif0.000214246
Etv5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.000620979
Pattern NameHomerSignificance
motif2.motif1.8448400000000002e-06
Etv6
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00169055
metacluster_1/pattern_180.0374606
Pattern NameHomerSignificance
motif2.motif0.00506877
Spi1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00172433
metacluster_1/pattern_180.049253
Pattern NameHomerSignificance
motif2.motif0.053543499999999994
Elf5
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0408491
metacluster_1/pattern_180.0440798
Pattern NameHomerSignificance
motif2.motif0.0295697
Elf1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0012384
Pattern NameHomerSignificance
motif2.motif0.00288736
Sp1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000307353
metacluster_1/pattern_190.031307999999999996
Pattern NameHomerSignificance
motif3.motif0.011529000000000001
Egr2
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0204718
Pattern NameHomerSignificance
motif3.motif0.05628330000000001
Nfyc
Pattern NameModiscoSignificance
metacluster_1/pattern_51.06659e-11
Pattern NameHomerSignificance
motif7.motif2.1905700000000003e-05
Klf12
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0079119
Pattern NameHomerSignificance
motif3.motif0.00919205
Tbx2
Pattern NameModiscoSignificance
metacluster_1/pattern_91.91558e-13
Pattern NameHomerSignificance
motif5.motif0.000131466
Yy1
Pattern NameModiscoSignificance
metacluster_1/pattern_103.929509999999999e-06
Pattern NameHomerSignificance
motif13.motif7.094189999999999e-05
Rel
Pattern NameModiscoSignificance
metacluster_1/pattern_140.00396571
Pattern NameHomerSignificance
motif15.motif0.0336286
Etv4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Pattern NameHomerSignificance
motif2.motif0.00177985
Irf2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00186309
Pattern NameHomerSignificance
motif14.motif0.0312127
Nrf1
Pattern NameModiscoSignificance
metacluster_1/pattern_49.29806e-06
Pattern NameHomerSignificance
motif8.motif6.988209999999999e-07
Taf1
Pattern NameModiscoSignificance
metacluster_1/pattern_102.71664e-06
Pattern NameHomerSignificance
motif13.motif0.017569799999999997
E2f4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000307353
Pattern NameHomerSignificance
motif3.motif0.000597242
Spdef
Pattern NameModiscoSignificance
metacluster_1/pattern_10.031112400000000002
Pattern NameHomerSignificance
motif2.motif0.0313682
Runx1
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00060075
Pattern NameHomerSignificance
motif4.motif0.019209999999999998
Zfp42
Pattern NameModiscoSignificance
metacluster_1/pattern_100.018902099999999998
Pattern NameHomerSignificance
motif13.motif0.00533933
Zfx
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0367342
metacluster_1/pattern_40.0209127
metacluster_1/pattern_190.0441958
Pattern NameHomerSignificance
motif3.motif0.0393506
Klf7
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000307353
Pattern NameHomerSignificance
motif3.motif0.000312352
Klf5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0113119
Pattern NameHomerSignificance
motif3.motif0.0118539
Prdm1
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000184113
Pattern NameHomerSignificance
motif14.motif0.0188996
Runx3
Pattern NameModiscoSignificance
metacluster_1/pattern_60.00190161
Pattern NameHomerSignificance
motif4.motif0.0224315
Elk3
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Pattern NameHomerSignificance
motif2.motif0.000225761
Klf1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.023196
Pattern NameHomerSignificance
motif3.motif0.0262839
Elf2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0121596
metacluster_1/pattern_180.0440798
Pattern NameHomerSignificance
motif2.motif0.015178799999999998
Nfyb
Pattern NameModiscoSignificance
metacluster_1/pattern_55.45173e-13
Pattern NameHomerSignificance
motif7.motif1.16284e-06
Nfkb2
Pattern NameModiscoSignificance
metacluster_1/pattern_143.35488e-05
Pattern NameHomerSignificance
motif15.motif0.00445137
Zfp143
Pattern NameModiscoSignificance
metacluster_1/pattern_92.5175100000000003e-21
Pattern NameHomerSignificance
motif5.motif3.9873299999999997e-05
Ctcfl
Pattern NameModiscoSignificance
metacluster_1/pattern_08.112589999999999e-08
metacluster_1/pattern_120.00489695
Pattern NameHomerSignificance
motif1.motif0.000630977
XP_911724.4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00194791
Pattern NameHomerSignificance
motif2.motif0.000225761
Nfya
Pattern NameModiscoSignificance
metacluster_1/pattern_55.82256e-10
Pattern NameHomerSignificance
motif7.motif1.03569e-05
Nfkb1
Pattern NameModiscoSignificance
metacluster_1/pattern_143.35488e-05
Pattern NameHomerSignificance
motif15.motif0.00248026
Foxi1
Pattern NameModiscoSignificance
metacluster_1/pattern_52.38151e-06
Pattern NameHomerSignificance
motif7.motif0.00159124
Fev
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00164815
Pattern NameHomerSignificance
motif2.motif0.00140577
Klf6
Pattern NameModiscoSignificance
metacluster_1/pattern_20.000350508
Pattern NameHomerSignificance
motif3.motif0.000597242
Pbx3
Pattern NameModiscoSignificance
metacluster_1/pattern_53.16922e-06
Pattern NameHomerSignificance
motif7.motif0.00114967
Rela
Pattern NameModiscoSignificance
metacluster_1/pattern_140.000295991
Pattern NameHomerSignificance
motif15.motif0.00445137
Etv2
Pattern NameModiscoSignificance
metacluster_1/pattern_13.4972100000000004e-05
metacluster_1/pattern_180.0183825
Pattern NameHomerSignificance
motif2.motif0.00037755199999999997
Zbtb33
Pattern NameModiscoSignificance
metacluster_1/pattern_192.43479e-05
Pattern NameHomerSignificance
motif11.motif5.39892e-05
Ets1
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00177964
metacluster_1/pattern_70.0442261
metacluster_1/pattern_180.0183825
Pattern NameHomerSignificance
motif2.motif0.000225761
Irf7
Pattern NameModiscoSignificance
metacluster_1/pattern_35.07321e-05
Pattern NameHomerSignificance
motif14.motif0.000912241
Irf1
Pattern NameModiscoSignificance
metacluster_1/pattern_31.06201e-14
Pattern NameHomerSignificance
motif14.motif0.012664
Erg
Pattern NameModiscoSignificance
metacluster_1/pattern_10.00177964
metacluster_1/pattern_180.049253
Pattern NameHomerSignificance
motif2.motif0.000225761
Unique TF-MoDISco TFs: #87
TF NameModiscoHomer
Srebf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00382226
Absent
Bhlhe40
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00669227
Absent
Rfx1
Pattern NameModiscoSignificance
metacluster_1/pattern_158.18746e-08
Absent
Nfil3
Pattern NameModiscoSignificance
metacluster_1/pattern_80.030807599999999997
Absent
Usf2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00871001
Absent
Nfia
Pattern NameModiscoSignificance
metacluster_1/pattern_201.39499e-06
Absent
Creb3l2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0234441
Absent
Nfe2l2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00671681
Absent
Gata4
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0119892
Absent
Tef
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0486921
Absent
Mitf
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0008571210000000001
Absent
Mafb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0225033
metacluster_1/pattern_130.0593726
Absent
Zfp740
Pattern NameModiscoSignificance
metacluster_1/pattern_20.025800999999999998
Absent
Zfp281
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0190587
Absent
Nfib
Pattern NameModiscoSignificance
metacluster_1/pattern_205.3986099999999995e-05
Absent
Mecom
Pattern NameModiscoSignificance
metacluster_1/pattern_160.028206799999999997
Absent
Zbtb1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0464527
Absent
Rfx3
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0187509
Absent
Sall4
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0561155
Absent
Egr3
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0297163
Absent
Tfe3
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0016954999999999997
Absent
Clock
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0234441
Absent
Creb1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00205641
metacluster_1/pattern_110.052365499999999995
Absent
Hlf
Pattern NameModiscoSignificance
metacluster_1/pattern_80.041936
metacluster_1/pattern_110.023496200000000002
Absent
Gata3
Pattern NameModiscoSignificance
metacluster_1/pattern_160.04399190000000001
Absent
Arnt
Pattern NameModiscoSignificance
metacluster_1/pattern_110.05950830000000001
Absent
Rfx6
Pattern NameModiscoSignificance
metacluster_1/pattern_150.0278685
Absent
Stat4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0178061
Absent
Nfic
Pattern NameModiscoSignificance
metacluster_1/pattern_200.030813599999999997
Absent
Rfx4
Pattern NameModiscoSignificance
metacluster_1/pattern_157.963930000000001e-05
Absent
Tal1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0132484
Absent
Rarg
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0551668
Absent
Tcfl5
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00750639
Absent
Fosb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00010441299999999999
Absent
Npas2
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00353966
Absent
Mycn
Pattern NameModiscoSignificance
metacluster_1/pattern_110.023796
Absent
Gata2
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00242891
Absent
Bach1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00811629
Absent
Usf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00928484
Absent
Creb5
Pattern NameModiscoSignificance
metacluster_1/pattern_80.000628739
Absent
Rxrb
Pattern NameModiscoSignificance
metacluster_1/pattern_80.0228524
Absent
Irf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00123095
Absent
Jund
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00224014
Absent
Atf3
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00022366400000000002
Absent
Gata1
Pattern NameModiscoSignificance
metacluster_1/pattern_160.00242891
Absent
Fos
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00016893599999999998
Absent
Tcf7
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00778413
Absent
Jdp2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00602312
metacluster_1/pattern_110.0358208
metacluster_1/pattern_133.77349e-06
Absent
Jun
Pattern NameModiscoSignificance
metacluster_1/pattern_80.03434980000000001
metacluster_1/pattern_130.047850300000000005
Absent
Atf1
Pattern NameModiscoSignificance
metacluster_1/pattern_80.026628700000000005
metacluster_1/pattern_110.021458500000000002
Absent
Tcf7l2
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00507919
metacluster_1/pattern_210.0176945
Absent
Bhlhe41
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0151535
Absent
Batf
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00671681
Absent
Batf3
Pattern NameModiscoSignificance
metacluster_1/pattern_30.00728942
Absent
Sp5
Pattern NameModiscoSignificance
metacluster_1/pattern_20.0190587
Absent
Ets2
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0284235
Absent
Tfec
Pattern NameModiscoSignificance
metacluster_1/pattern_80.039260699999999996
metacluster_1/pattern_110.00161745
Absent
Atf7
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00106851
metacluster_1/pattern_110.023796
Absent
Atf2
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00124862
metacluster_1/pattern_110.054304899999999996
Absent
Mafk
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0586818
Absent
Lef1
Pattern NameModiscoSignificance
metacluster_1/pattern_172.22035e-06
Absent
Tcf3
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00010319
Absent
Arntl
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00931375
Absent
Stat2
Pattern NameModiscoSignificance
metacluster_1/pattern_30.000733015
Absent
Max
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0222577
Absent
Irf8
Pattern NameModiscoSignificance
metacluster_1/pattern_10.0237626
metacluster_1/pattern_36.64035e-06
Absent
Stat1
Pattern NameModiscoSignificance
metacluster_1/pattern_32.33491e-05
Absent
Dbp
Pattern NameModiscoSignificance
metacluster_1/pattern_80.03434980000000001
metacluster_1/pattern_110.0369053
Absent
Fosl2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.000527208
Absent
Gata6
Pattern NameModiscoSignificance
metacluster_1/pattern_160.0305278
Absent
Zbtb17
Pattern NameModiscoSignificance
metacluster_1/pattern_20.006342800000000001
Absent
Mafa
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0441625
Absent
Fosl1
Pattern NameModiscoSignificance
metacluster_1/pattern_130.032144900000000004
Absent
Srebf1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.029196499999999997
Absent
Rfx7
Pattern NameModiscoSignificance
metacluster_1/pattern_150.00723346
Absent
Irf4
Pattern NameModiscoSignificance
metacluster_1/pattern_10.028145999999999997
metacluster_1/pattern_30.022150599999999996
Absent
Junb
Pattern NameModiscoSignificance
metacluster_1/pattern_130.0113558
Absent
Tfeb
Pattern NameModiscoSignificance
metacluster_1/pattern_110.00034199699999999997
Absent
Nfe2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00635934
Absent
Bach2
Pattern NameModiscoSignificance
metacluster_1/pattern_130.00436624
Absent
Myc
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0369053
Absent
Rfx2
Pattern NameModiscoSignificance
metacluster_1/pattern_151.8779699999999997e-07
Absent
Tcf7l1
Pattern NameModiscoSignificance
metacluster_1/pattern_170.00027949
Absent
E2f1
Pattern NameModiscoSignificance
metacluster_1/pattern_20.013060200000000001
Absent
Mlx
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0109767
Absent
Xbp1
Pattern NameModiscoSignificance
metacluster_1/pattern_110.0551668
Absent
Crem
Pattern NameModiscoSignificance
metacluster_1/pattern_80.00602312
Absent
Unique Homer TFs: #0
TF NameModiscoHomer