# Parameters
data_name = "ES;E14;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_50-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_50-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:50:50,445 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	ES cells (E14)
Cell Group	ES cells and embryonic tissues
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	179336	106127	10.4351	45721770	7790322	0.1705	4490451	0.0983	18284831	0.4001

Modelling Metadata

Metric	Value
auPRC	0.5586
Calibrated Recall at 50% FDR	0.252
Number of Positive Examples in Test Data	116933
Number of Negative Examples in Test Data	7953918
Imbalance Ratio in Test Data	0.0145
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #23

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 3122 SequenceContrib ScoresHyp_Contrib Scores	Klf1, Klf3, Klf4, Sp4, Klf7, Klf8, Klf12, Klf6, Sp2, Klf5, Sp3, Sp1, Egr1, E2f4, Egr2
metacluster_1/pattern_1 # seqlets: 2948 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 2388 SequenceContrib ScoresHyp_Contrib Scores	Pou5f1, Nanog, Sox2, Pou2f2, Lef1, Pou2f1
metacluster_1/pattern_3 # seqlets: 1715 SequenceContrib ScoresHyp_Contrib Scores	Sox3, Sox4, Sox6, Sox17, Sry, Sox12, Sox14, Sox7, Sox8, Sox11, Sox5, Sox18, Sox9, Cux2, Sox10, Sox21, Tcf7, Sox15, Sox30
metacluster_1/pattern_4 # seqlets: 1687 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_5 # seqlets: 1416 SequenceContrib ScoresHyp_Contrib Scores	Sp5, Zbtb17, Zfp281, Wt1, Ptf1a, Nhlh1
metacluster_1/pattern_6 # seqlets: 1028 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_7 # seqlets: 997 SequenceContrib ScoresHyp_Contrib Scores	Gabpa, Elk1, Elk4, Fli1, Ets1, Erg, Elk3, Etv5, Elf1, Etv4, Fev, Etv1, Etv6, Etv3, XP_911724.4, Etv2, Ehf, Elf5, Elf4, Elf2, Spi1, Spdef, Elf3, Spic, Spib
metacluster_1/pattern_8 # seqlets: 920 SequenceContrib ScoresHyp_Contrib Scores	Tead4, Tead2, Tead1
metacluster_1/pattern_9 # seqlets: 772 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_10 # seqlets: 548 SequenceContrib ScoresHyp_Contrib Scores	Tcf7l2, Tcf7l1, Tcf3, Nr2f6
metacluster_1/pattern_11 # seqlets: 488 SequenceContrib ScoresHyp_Contrib Scores	Usf1, Usf2, Tfec, Tfeb, Mitf, Arntl, Srebf1, Tfe3, Bhlhe40, Clock, Mlx, Arnt, Npas2, Srebf2, Creb3l2, Tcfl5, Atf1, Bhlhe41, Max, Xbp1, Arnt2, Mycn, Dbp, Mlxip, Myc, Hlf
metacluster_1/pattern_12 # seqlets: 464 SequenceContrib ScoresHyp_Contrib Scores	Rfx2, Rfx1, Rfx3, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_13 # seqlets: 394 SequenceContrib ScoresHyp_Contrib Scores	Zic2, Zic3
metacluster_1/pattern_14 # seqlets: 360 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_15 # seqlets: 314 SequenceContrib ScoresHyp_Contrib Scores	Creb1, Atf2, Crem, Atf7, Jdp2, Creb5, Atf3, Fosl2, Jun
metacluster_1/pattern_16 # seqlets: 310 SequenceContrib ScoresHyp_Contrib Scores	Nr5a2, Esrrg, Rarg, Esrra
metacluster_1/pattern_17 # seqlets: 248 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_18 # seqlets: 246 SequenceContrib ScoresHyp_Contrib Scores	Tcfcp2l1, Trp53, Trp63, Trp73
metacluster_1/pattern_19 # seqlets: 177 SequenceContrib ScoresHyp_Contrib Scores	Fosl1, Mafk, Fos, Mafg, Mafb, Maff, Maf, Bach2, Jund, Batf, Fosb, Junb, Mafa, Nfe2l2, Nfe2, Bach1
metacluster_1/pattern_20 # seqlets: 114 SequenceContrib ScoresHyp_Contrib Scores	Six2, Six1, Six4
metacluster_1/pattern_21 # seqlets: 61 SequenceContrib ScoresHyp_Contrib Scores	Rest
metacluster_1/pattern_22 # seqlets: 60 SequenceContrib ScoresHyp_Contrib Scores

Click here for Motifs by TF-MoDISco: #160

TF Name	Pattern(s)
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_0 4.6921499999999995e-05 metacluster_1/pattern_5 0.0219806
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_0 6.38888e-09 metacluster_1/pattern_5 0.00193751
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00025645400000000004 metacluster_1/pattern_5 0.017005000000000003
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0354222 metacluster_1/pattern_5 0.0470352
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_0 6.20712e-06 metacluster_1/pattern_5 0.021857599999999998
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_0 6.20712e-06 metacluster_1/pattern_5 0.026057099999999996
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_0 6.651979999999999e-05 metacluster_1/pattern_5 0.037027199999999996
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_0 2.03027e-05 metacluster_1/pattern_5 0.00784772
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000223783 metacluster_1/pattern_5 0.00193751
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00025645400000000004
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000340256 metacluster_1/pattern_5 0.0014724
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.029139299999999996 metacluster_1/pattern_5 0.037027199999999996
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00919345 metacluster_1/pattern_5 0.020735299999999998
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00724679 metacluster_1/pattern_5 0.017005000000000003
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0217429 metacluster_1/pattern_5 0.0348471
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 1.66895e-14
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 1.96502e-09
Pou5f1	Pattern Name Modisco Significance metacluster_1/pattern_2 1.8502599999999998e-06 metacluster_1/pattern_3 0.0237469
Nanog	Pattern Name Modisco Significance metacluster_1/pattern_2 7.37324e-09 metacluster_1/pattern_3 0.00023442099999999998
Sox2	Pattern Name Modisco Significance metacluster_1/pattern_2 4.71061e-06 metacluster_1/pattern_3 0.00716875
Pou2f2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0335111
Lef1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0251102 metacluster_1/pattern_3 0.00559571 metacluster_1/pattern_10 2.5377e-09
Pou2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0556174
Sox3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.030695799999999995
Sox4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0080676
Sox6	Pattern Name Modisco Significance metacluster_1/pattern_3 0.030060700000000003
Sox17	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00306969
Sry	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00709024
Sox12	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00709024
Sox14	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00939229
Sox7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.012827600000000002
Sox8	Pattern Name Modisco Significance metacluster_1/pattern_3 0.013731899999999998
Sox11	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0151101
Sox5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.045825599999999994
Sox18	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0151101
Sox9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0381123
Cux2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0381123
Sox10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0381123
Sox21	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0404267
Tcf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0437896 metacluster_1/pattern_10 0.00942499
Sox15	Pattern Name Modisco Significance metacluster_1/pattern_3 0.052532
Sox30	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0531485
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00784772
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0100122
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_5 0.020362
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.021857599999999998
Ptf1a	Pattern Name Modisco Significance metacluster_1/pattern_5 0.025059400000000003
Nhlh1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0433283
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_6 1.22069e-11
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_6 1.28008e-10
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_6 5.97109e-10
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_6 1.13009e-07
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_6 1.2311700000000001e-05
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000575718
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000547948
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000610425
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000989295
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000776276
Erg	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000989295
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000523287
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000290397
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00045137199999999996
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00285633
Fev	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000605155
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000610425
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0109559
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0013129
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00140427
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0022761999999999995
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0208067
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0253253
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00345332
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00555679
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0355442
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00854378
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0463785
Spic	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0317642
Spib	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0355442
Tead4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00220055
Tead2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00393342
Tead1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00766978
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_9 8.54165e-07
Tcf7l2	Pattern Name Modisco Significance metacluster_1/pattern_10 2.80645e-05
Tcf7l1	Pattern Name Modisco Significance metacluster_1/pattern_10 8.378059999999999e-05
Tcf3	Pattern Name Modisco Significance metacluster_1/pattern_10 7.744289999999999e-06
Nr2f6	Pattern Name Modisco Significance metacluster_1/pattern_10 0.0392403
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00171633
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00189984 metacluster_1/pattern_15 0.00039103900000000003
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00153582
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00100203
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00100203
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00534477
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00404797
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00164201 metacluster_1/pattern_15 0.03284840000000001
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_11 0.009662100000000002
Clock	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0350655
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0173257
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0424327
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00384348
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00426627
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0175507
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00944536
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00944536 metacluster_1/pattern_15 0.0571486
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0165886
Max	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0369958
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0369958
Arnt2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0503331
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0535073
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0543906
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0552982
Myc	Pattern Name Modisco Significance metacluster_1/pattern_11 0.056491999999999994
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_11 0.056491999999999994
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_12 3.3141e-08 metacluster_1/pattern_14 0.039801199999999995
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_12 9.64344e-07
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0262383
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.000141327
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0128381 metacluster_1/pattern_14 0.039801199999999995
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0262383 metacluster_1/pattern_14 0.00067596
Zic2	Pattern Name Modisco Significance metacluster_1/pattern_13 8.081470000000001e-07
Zic3	Pattern Name Modisco Significance metacluster_1/pattern_13 3.30403e-05
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00494695
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00232172
Crem	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0303454
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_15 0.000996225
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00424211 metacluster_1/pattern_19 0.00397914
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00274058
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0500751 metacluster_1/pattern_19 0.000107817
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0460436 metacluster_1/pattern_19 2.06237e-05
Jun	Pattern Name Modisco Significance metacluster_1/pattern_15 0.05928390000000001 metacluster_1/pattern_19 2.42333e-05
Nr5a2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.037056
Esrrg	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000430705
Rarg	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0127479
Esrra	Pattern Name Modisco Significance metacluster_1/pattern_16 0.042943699999999994
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_17 1.98491e-21
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_17 7.86506e-19
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_17 1.17691e-12
Tcfcp2l1	Pattern Name Modisco Significance metacluster_1/pattern_18 7.429210000000001e-06
Trp53	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0273166
Trp63	Pattern Name Modisco Significance metacluster_1/pattern_18 0.014928499999999999
Trp73	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0273166
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_19 6.48226e-06
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_19 2.3918e-05
Fos	Pattern Name Modisco Significance metacluster_1/pattern_19 2.06237e-05
Mafg	Pattern Name Modisco Significance metacluster_1/pattern_19 3.15649e-05
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000386556
Maff	Pattern Name Modisco Significance metacluster_1/pattern_19 7.599810000000001e-05
Maf	Pattern Name Modisco Significance metacluster_1/pattern_19 8.365e-05
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000179233
Jund	Pattern Name Modisco Significance metacluster_1/pattern_19 0.057248099999999996
Batf	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0461066
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000386556
Junb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0230204
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00057363
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00277981
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0009485460000000001
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00397914
Six2	Pattern Name Modisco Significance metacluster_1/pattern_20 1.9849400000000004e-10
Six1	Pattern Name Modisco Significance metacluster_1/pattern_20 1.78301e-06
Six4	Pattern Name Modisco Significance metacluster_1/pattern_20 7.05439e-06
Rest	Pattern Name Modisco Significance metacluster_1/pattern_21 2.54589e-11 metacluster_1/pattern_22 5.80782e-11

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #55

TF Name	Modisco	Homer
Tcf7l1	Pattern Name Modisco Significance metacluster_1/pattern_10 8.378059999999999e-05	Pattern Name Homer Significance motif7.motif 0.0582135
Pou5f1	Pattern Name Modisco Significance metacluster_1/pattern_2 1.8502599999999998e-06 metacluster_1/pattern_3 0.0237469	Pattern Name Homer Significance motif3.motif 3.2793700000000003e-07 motif7.motif 0.00737042
Sox6	Pattern Name Modisco Significance metacluster_1/pattern_3 0.030060700000000003	Pattern Name Homer Significance motif7.motif 0.011410700000000001
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_17 1.98491e-21	Pattern Name Homer Significance motif5.motif 7.281810000000002e-08
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_0 6.20712e-06 metacluster_1/pattern_5 0.026057099999999996	Pattern Name Homer Significance motif2.motif 0.00160408
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_0 6.651979999999999e-05 metacluster_1/pattern_5 0.037027199999999996	Pattern Name Homer Significance motif2.motif 0.0284144
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00274058	Pattern Name Homer Significance motif12.motif 0.0162355
Tcf3	Pattern Name Modisco Significance metacluster_1/pattern_10 7.744289999999999e-06	Pattern Name Homer Significance motif7.motif 0.0493183
Sox21	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0404267	Pattern Name Homer Significance motif7.motif 0.00215591
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00424211 metacluster_1/pattern_19 0.00397914	Pattern Name Homer Significance motif12.motif 0.0436467
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_17 1.17691e-12	Pattern Name Homer Significance motif5.motif 9.76163e-06
Sox7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.012827600000000002	Pattern Name Homer Significance motif7.motif 0.00919108
Sry	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00709024	Pattern Name Homer Significance motif7.motif 0.00910935
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_6 5.97109e-10	Pattern Name Homer Significance motif4.motif 1.1147500000000001e-07
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 1.66895e-14	Pattern Name Homer Significance motif1.motif 0.00055501
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00944536 metacluster_1/pattern_15 0.0571486	Pattern Name Homer Significance motif12.motif 0.0436467
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00724679 metacluster_1/pattern_5 0.017005000000000003	Pattern Name Homer Significance motif2.motif 0.00101501
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_0 4.6921499999999995e-05 metacluster_1/pattern_5 0.0219806	Pattern Name Homer Significance motif2.motif 0.0473511
Sox14	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00939229	Pattern Name Homer Significance motif7.motif 0.00728077
Sox17	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00306969	Pattern Name Homer Significance motif7.motif 0.0225086
Tcf7l2	Pattern Name Modisco Significance metacluster_1/pattern_10 2.80645e-05	Pattern Name Homer Significance motif7.motif 0.00951879
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_0 2.03027e-05 metacluster_1/pattern_5 0.00784772	Pattern Name Homer Significance motif2.motif 0.00243326
Tcf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0437896 metacluster_1/pattern_10 0.00942499	Pattern Name Homer Significance motif7.motif 0.0122812
Sox5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.045825599999999994	Pattern Name Homer Significance motif7.motif 0.0171558
Sox18	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0151101	Pattern Name Homer Significance motif7.motif 0.0104907
Sox30	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0531485	Pattern Name Homer Significance motif7.motif 0.0007727869999999999
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_6 1.28008e-10	Pattern Name Homer Significance motif4.motif 1.1147500000000001e-07
Nanog	Pattern Name Modisco Significance metacluster_1/pattern_2 7.37324e-09 metacluster_1/pattern_3 0.00023442099999999998	Pattern Name Homer Significance motif3.motif 3.0899200000000004e-06 motif7.motif 0.00011410200000000001
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_0 6.38888e-09 metacluster_1/pattern_5 0.00193751	Pattern Name Homer Significance motif2.motif 0.00101501
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0354222 metacluster_1/pattern_5 0.0470352	Pattern Name Homer Significance motif2.motif 0.033245300000000005
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_17 7.86506e-19	Pattern Name Homer Significance motif5.motif 4.66926e-08
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00494695	Pattern Name Homer Significance motif12.motif 0.0237007
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_6 1.2311700000000001e-05	Pattern Name Homer Significance motif4.motif 5.80665e-05
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 1.96502e-09	Pattern Name Homer Significance motif1.motif 0.0009215019999999999
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_6 1.22069e-11	Pattern Name Homer Significance motif4.motif 1.79946e-10
Sox3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.030695799999999995	Pattern Name Homer Significance motif7.motif 0.0347236
Sox11	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0151101	Pattern Name Homer Significance motif7.motif 0.00484302
Sox4	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0080676	Pattern Name Homer Significance motif7.motif 0.00206934
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.029139299999999996 metacluster_1/pattern_5 0.037027199999999996	Pattern Name Homer Significance motif2.motif 0.0174763
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00025645400000000004 metacluster_1/pattern_5 0.017005000000000003	Pattern Name Homer Significance motif2.motif 0.00101501
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000223783 metacluster_1/pattern_5 0.00193751	Pattern Name Homer Significance motif2.motif 0.00160408
Sox9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0381123	Pattern Name Homer Significance motif7.motif 0.0393177
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_15 0.000996225	Pattern Name Homer Significance motif12.motif 0.0322978
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00025645400000000004	Pattern Name Homer Significance motif2.motif 0.0284144
Sox2	Pattern Name Modisco Significance metacluster_1/pattern_2 4.71061e-06 metacluster_1/pattern_3 0.00716875	Pattern Name Homer Significance motif3.motif 5.469740000000001e-06 motif7.motif 0.0007727869999999999
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_9 8.54165e-07	Pattern Name Homer Significance motif11.motif 0.00030272
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000340256 metacluster_1/pattern_5 0.0014724	Pattern Name Homer Significance motif2.motif 0.00242236
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00919345 metacluster_1/pattern_5 0.020735299999999998	Pattern Name Homer Significance motif2.motif 0.028629500000000002
Sox12	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00709024	Pattern Name Homer Significance motif7.motif 0.00206934
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_15 0.00232172	Pattern Name Homer Significance motif12.motif 0.035416199999999995
Sox8	Pattern Name Modisco Significance metacluster_1/pattern_3 0.013731899999999998	Pattern Name Homer Significance motif7.motif 0.008808499999999999
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_0 6.20712e-06 metacluster_1/pattern_5 0.021857599999999998	Pattern Name Homer Significance motif2.motif 0.00101501
Crem	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0303454	Pattern Name Homer Significance motif12.motif 0.0237007
Lef1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0251102 metacluster_1/pattern_3 0.00559571 metacluster_1/pattern_10 2.5377e-09	Pattern Name Homer Significance motif7.motif 0.0101831
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_6 1.13009e-07	Pattern Name Homer Significance motif4.motif 5.567940000000001e-07

Unique TF-MoDISco TFs: #105

TF Name	Modisco	Homer
Tead4	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00220055	Absent
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00171633	Absent
Batf	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0461066	Absent
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000575718	Absent
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_19 2.3918e-05	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0262383	Absent
Esrra	Pattern Name Modisco Significance metacluster_1/pattern_16 0.042943699999999994	Absent
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000547948	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_12 3.3141e-08 metacluster_1/pattern_14 0.039801199999999995	Absent
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0022761999999999995	Absent
Tcfcp2l1	Pattern Name Modisco Significance metacluster_1/pattern_18 7.429210000000001e-06	Absent
Mafg	Pattern Name Modisco Significance metacluster_1/pattern_19 3.15649e-05	Absent
Tead2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00393342	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0262383 metacluster_1/pattern_14 0.00067596	Absent
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00397914	Absent
Pou2f2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0335111	Absent
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0535073	Absent
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0013129	Absent
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000610425	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00153582	Absent
Jund	Pattern Name Modisco Significance metacluster_1/pattern_19 0.057248099999999996	Absent
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0355442	Absent
Erg	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000989295	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_12 9.64344e-07	Absent
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_11 0.056491999999999994	Absent
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_5 0.020362	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0165886	Absent
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0463785	Absent
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00555679	Absent
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00854378	Absent
Maf	Pattern Name Modisco Significance metacluster_1/pattern_19 8.365e-05	Absent
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000776276	Absent
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000989295	Absent
Max	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0369958	Absent
Fev	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000605155	Absent
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00164201 metacluster_1/pattern_15 0.03284840000000001	Absent
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00100203	Absent
Zic2	Pattern Name Modisco Significance metacluster_1/pattern_13 8.081470000000001e-07	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.000141327	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00404797	Absent
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00140427	Absent
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000386556	Absent
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00057363	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00100203	Absent
Pou2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0556174	Absent
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000523287	Absent
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0500751 metacluster_1/pattern_19 0.000107817	Absent
Esrrg	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000430705	Absent
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000386556	Absent
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.00277981	Absent
Trp73	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0273166	Absent
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0109559	Absent
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0460436 metacluster_1/pattern_19 2.06237e-05	Absent
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00784772	Absent
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0217429 metacluster_1/pattern_5 0.0348471	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0350655	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00426627	Absent
Nr2f6	Pattern Name Modisco Significance metacluster_1/pattern_10 0.0392403	Absent
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.000179233	Absent
Tead1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00766978	Absent
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000610425	Absent
Rarg	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0127479	Absent
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0369958	Absent
Nhlh1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0433283	Absent
Fos	Pattern Name Modisco Significance metacluster_1/pattern_19 2.06237e-05	Absent
Zic3	Pattern Name Modisco Significance metacluster_1/pattern_13 3.30403e-05	Absent
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00285633	Absent
Spic	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0317642	Absent
Ptf1a	Pattern Name Modisco Significance metacluster_1/pattern_5 0.025059400000000003	Absent
Maff	Pattern Name Modisco Significance metacluster_1/pattern_19 7.599810000000001e-05	Absent
Sox10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0381123	Absent
Sox15	Pattern Name Modisco Significance metacluster_1/pattern_3 0.052532	Absent
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0100122	Absent
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00189984 metacluster_1/pattern_15 0.00039103900000000003	Absent
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00534477	Absent
Trp63	Pattern Name Modisco Significance metacluster_1/pattern_18 0.014928499999999999	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0173257	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0128381 metacluster_1/pattern_14 0.039801199999999995	Absent
Junb	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0230204	Absent
Arnt2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0503331	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_11 0.009662100000000002	Absent
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000290397	Absent
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_19 6.48226e-06	Absent
Spib	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0355442	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00384348	Absent
Jun	Pattern Name Modisco Significance metacluster_1/pattern_15 0.05928390000000001 metacluster_1/pattern_19 2.42333e-05	Absent
Six2	Pattern Name Modisco Significance metacluster_1/pattern_20 1.9849400000000004e-10	Absent
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0208067	Absent
Trp53	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0273166	Absent
Six4	Pattern Name Modisco Significance metacluster_1/pattern_20 7.05439e-06	Absent
Rest	Pattern Name Modisco Significance metacluster_1/pattern_21 2.54589e-11 metacluster_1/pattern_22 5.80782e-11	Absent
Nr5a2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.037056	Absent
Six1	Pattern Name Modisco Significance metacluster_1/pattern_20 1.78301e-06	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.021857599999999998	Absent
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_19 0.0009485460000000001	Absent
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0543906	Absent
Cux2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0381123	Absent
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0424327	Absent
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0175507	Absent
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00045137199999999996	Absent
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00345332	Absent
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0253253	Absent
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0552982	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00944536	Absent
Myc	Pattern Name Modisco Significance metacluster_1/pattern_11 0.056491999999999994	Absent

Unique Homer TFs: #2

TF Name	Modisco	Homer
Zbtb33	Absent	Pattern Name Homer Significance motif17.motif 4.57341e-05
Zfx	Absent	Pattern Name Homer Significance motif2.motif 0.0252037