In [1]:
# Parameters
data_name = "Pou2f2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:28:34,150 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Pou2f2: Motif: M09224_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Pou2f2: #46

Cell typeModiscoHomer
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00656218

Pattern: motif4.motif

Significance: 0.021762200000000002

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0103644

Pattern: motif5.motif

Significance: 0.05222919999999999

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0068619

Pattern: motif3.motif

Significance: 0.019608900000000002

immatureB;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00686678

Pattern: motif17.motif

Significance: 0.031211900000000004

MZ_B;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00718319

Pattern: motif19.motif

Significance: 0.0329103

B1_B;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00342403

Pattern: motif14.motif

Significance: 0.00544922

GC_B;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.00980301

Pattern: motif4.motif

Significance: 0.000734348

plasmaB;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0109896

Pattern: motif3.motif

Significance: 0.00652348

aB;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0104508

Pattern: motif4.motif

Significance: 0.00100785

aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.016550400000000003

Pattern: motif14.motif

Significance: 0.000936014

aB_LPS+IL21;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0111015

Pattern: motif14.motif

Significance: 0.00544652

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00309202

Pattern: motif5.motif

Significance: 0.00740759

aB_CD40+IL4;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00610619

Pattern: motif20.motif

Significance: 0.016439099999999998

B_SPLND;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00851748

Pattern: motif16.motif

Significance: 0.00324914

CH12.LX;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0104831

Pattern: motif5.motif

Significance: 0.0334547

ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00834232

Pattern: motif5.motif

Significance: 0.0437358

CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0209423

Pattern: motif8.motif

Significance: 0.044531

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.00231128

/

Pattern: metacluster_0/pattern_21

Significance: 0.0314881

Pattern: motif16.motif

Significance: 0.0399915

BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00640053

Pattern: motif9.motif

Significance: 0.017569400000000002

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00128068

Pattern: motif18.motif

Significance: 0.026231099999999997

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.03823819999999999

Pattern: motif16.motif

Significance: 0.0425761

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00421285

/

Pattern: metacluster_1/pattern_19

Significance: 0.0002274

Pattern: motif13.motif

Significance: 0.0176275

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.038342

Pattern: motif3.motif

Significance: 0.045889599999999996

ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00835704

Pattern: motif15.motif

Significance: 0.044447

ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00716985

Pattern: motif18.motif

Significance: 0.0268788

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.026813599999999996

Pattern: motif3.motif

Significance: 0.031620999999999996

ES;D0;D;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00784362

Pattern: motif6.motif

Significance: 0.0169815

aB;CD180;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00207843

Pattern: motif14.motif

Significance: 0.013282200000000001

ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0320383

Pattern: motif4.motif

Significance: 0.0395679

ES;E14;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0487003

Pattern: motif5.motif

Significance: 0.0331865

CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00415345

Pattern: motif5.motif

Significance: 0.0150287

wCH12;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00756513

Pattern: motif4.motif

Significance: 0.00551371

CH12;med14;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00729603

Pattern: motif6.motif

Significance: 0.00483249

wCH12_drug;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.012734

Pattern: motif10.motif

Significance: 0.0157248

ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0547164

Pattern: motif9.motif

Significance: 0.013761099999999998

ES;J1;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0327337

Pattern: motif6.motif

Significance: 0.0520876

ES;E14;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0381472

Pattern: motif5.motif

Significance: 0.027448200000000002

ES;F1216;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0534078

Pattern: motif7.motif

Significance: 0.0150155

ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0374337

Pattern: motif4.motif

Significance: 0.0489381

ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0404559

Pattern: motif4.motif

Significance: 0.0213144

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00582637

/

Pattern: metacluster_0/pattern_19

Significance: 0.025964099999999997

Pattern: motif2.motif

Significance: 0.038074800000000006

Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00610365

Pattern: motif4.motif

Significance: 0.00746909

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0039585

/

Pattern: metacluster_0/pattern_15

Significance: 0.044095

Pattern: motif2.motif

Significance: 0.0476283

/

Pattern: motif25.motif

Significance: 0.000311655

wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00546062

/

Pattern: metacluster_0/pattern_14

Significance: 0.020228799999999998

Pattern: motif3.motif

Significance: 0.0151553

Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.011554799999999999

Pattern: motif14.motif

Significance: 0.0222588

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.00749245

/

Pattern: metacluster_1/pattern_8

Significance: 0.00305021

/

Pattern: metacluster_1/pattern_17

Significance: 0.0006872610000000001

Pattern: motif24.motif

Significance: 0.033292800000000004

Unique Cell types only TF-MoDISco finds Pou2f2: #99

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.00297181

Absent
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00722306

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0034823999999999996

Absent
proB;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00965748

Absent
preB;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.013936099999999998

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00786214

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.006988600000000001

Absent
aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.00473137

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.0430501

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_16

Significance: 0.0520839

Absent
NTRPHL;A;CL

Pattern: metacluster_1/pattern_18

Significance: 7.720390000000001e-05

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00372249

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00455992

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00836476

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00773334

Absent
naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0372603

Absent
CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00554619

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.00522244

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00663835

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0335111

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_19

Significance: 0.052637199999999995

Absent
Adipose;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.052409000000000004

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_22

Significance: 0.00409383

Absent
PNCRS;A;CL

Pattern: metacluster_0/pattern_15

Significance: 0.032430400000000005

Absent
eye-NRL_RTN;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.00277664

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.0191998

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.04416919999999999

/

Pattern: metacluster_1/pattern_20

Significance: 0.000574922

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00129243

/

Pattern: metacluster_1/pattern_24

Significance: 2.4924499999999998e-05

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0186035

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.000773149

Absent
restingB;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00505854

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.022748599999999997

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00398274

Absent
gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00652377

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00660397

Absent
NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.000165422

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00159536

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.000153084

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.035832199999999995

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00928992

Absent
mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.000225582

Absent
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.000776641

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00446988

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.021606999999999998

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0118546

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.000269315

Absent
ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0148957

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00921033

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.000164841

Absent
TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0120712

Absent
Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 9.12246e-05

Absent
T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00504725

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00430945

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00321162

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00472836

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_22

Significance: 0.0366327

Absent
MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00804082

Absent
Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.00102234

Absent
DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_24

Significance: 0.025544900000000002

Absent
DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.022925599999999997

Absent
ROD_PHT_RCPTR_RTN;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0270651

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.019113099999999997

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.000403305

/

Pattern: metacluster_0/pattern_16

Significance: 0.017941299999999997

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0206581

/

Pattern: metacluster_0/pattern_17

Significance: 0.00080545

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0111745

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.000157489

/

Pattern: metacluster_0/pattern_21

Significance: 0.00748465

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.0124131

/

Pattern: metacluster_0/pattern_22

Significance: 0.00141245

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.00150912

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00459458

/

Pattern: metacluster_0/pattern_21

Significance: 0.0183759

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.029876

/

Pattern: metacluster_0/pattern_20

Significance: 0.00345136

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0511679

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0208899

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.00395037

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.033445300000000004

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0181563

/

Pattern: metacluster_1/pattern_20

Significance: 0.030201599999999995

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.05702669999999999

/

Pattern: metacluster_1/pattern_18

Significance: 0.042293

Absent
ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.000598573

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.0266153

Absent
eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00408128

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0402754

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_17

Significance: 0.0156509

Absent
ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00120307

Absent
T_SPLND_blstCLTRD;CD4+;D;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0121092

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00884687

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.00735844

/

Pattern: metacluster_0/pattern_7

Significance: 0.00424612

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.050884

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.039693

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00335047

/

Pattern: metacluster_0/pattern_25

Significance: 0.00730612

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.00669069

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.0225004

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0245457

/

Pattern: metacluster_1/pattern_11

Significance: 0.00110938

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00483101

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00179696

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.00463216

/

Pattern: metacluster_0/pattern_11

Significance: 0.00514383

Absent
wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00181187

/

Pattern: metacluster_0/pattern_26

Significance: 0.03578169999999999

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0322059

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00267342

Absent
Spleen;8wks;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.00551132

Absent
A20;B-lymphoma;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0338846

Absent
Unique Cell types only Homer finds Pou2f2: #3

Cell typeModiscoHomer
BL_CN_PHT_RCPTR;A;GEOAbsent

Pattern: motif13.motif

Significance: 0.0348901

wES;FaceP;E11.5;D;EnAbsent

Pattern: motif3.motif

Significance: 0.057635000000000006

Melanotrope;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.023455700000000003