In [1]:
# Parameters
data_name = "Mafg"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:18:43,111 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Mafg: Motif: M08835_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Mafg: #31

Cell typeModiscoHomer
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.05930509999999999

Pattern: motif18.motif

Significance: 0.04918959999999999

3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0451033

Pattern: motif1.motif

Significance: 0.020680599999999997

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0231412

Pattern: motif3.motif

Significance: 0.000552581

AML;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00246633

Pattern: motif13.motif

Significance: 0.0337704

Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00238802

Pattern: motif19.motif

Significance: 2.90343e-06

AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00325726

Pattern: motif15.motif

Significance: 0.000163762

MEF.GATA-1-ER;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00452942

Pattern: motif23.motif

Significance: 0.00028213

NIH3T3;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0319087

Pattern: motif2.motif

Significance: 0.0139553

MN1;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.0571012

Pattern: motif3.motif

Significance: 0.026365800000000002

3T3-L1;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0356457

Pattern: motif1.motif

Significance: 0.0081779

MCRPHG;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.021782

Pattern: motif3.motif

Significance: 0.00213735

Erythroblast;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00231423

Pattern: motif19.motif

Significance: 0.00881238

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0207867

/

Pattern: metacluster_1/pattern_10

Significance: 0.00885602

Pattern: motif7.motif

Significance: 0.0199348

EPP;A;En

Pattern: metacluster_1/pattern_12

Significance: 0.00174608

Pattern: motif21.motif

Significance: 0.00150825

pErythroblast;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.0039585

Pattern: motif16.motif

Significance: 0.024134700000000002

MegP;A;En

Pattern: metacluster_1/pattern_8

Significance: 0.00317644

Pattern: motif15.motif

Significance: 0.00710012

pCMP;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.00298493

Pattern: motif12.motif

Significance: 0.0130762

DC;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.0473136

Pattern: motif3.motif

Significance: 0.00384867

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00162529

Pattern: motif26.motif

Significance: 9.072649999999999e-05

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00605384

Pattern: motif2.motif

Significance: 0.0110146

3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_0

Significance: 0.04530580000000001

Pattern: motif1.motif

Significance: 0.00955507

gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0475812

Pattern: motif13.motif

Significance: 0.0201894

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0522259

Pattern: motif2.motif

Significance: 0.0239524

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_13

Significance: 0.00295686

Pattern: motif17.motif

Significance: 0.00366605

ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00613149

Pattern: motif3.motif

Significance: 0.0198133

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0031854

Pattern: motif15.motif

Significance: 0.0347902

Adipose;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0380615

Pattern: motif14.motif

Significance: 0.027754900000000002

EP;c-kit+CD71+Ter119+;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00334552

Pattern: motif16.motif

Significance: 0.00213668

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.00971224

Pattern: motif4.motif

Significance: 0.00141534

T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0597793

Pattern: motif18.motif

Significance: 0.0371071

TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0591026

Pattern: motif22.motif

Significance: 0.0465827

Unique Cell types only TF-MoDISco finds Mafg: #74

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0026438000000000004

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.029992599999999998

Absent
proB;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00492515

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_21

Significance: 0.0318

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0243945

Absent
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0146459

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00611205

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.011947200000000002

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.00331674

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.043711

Absent
aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.053940300000000004

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.0489441

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00531762

Absent
MEL;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00248318

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_9

Significance: 0.00509254

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_9

Significance: 0.01567

Absent
NTRPHL;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0423286

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.028355

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.027179000000000002

Absent
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00333697

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.056432500000000003

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0352216

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0583521

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0452933

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00109533

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0578001

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.015480700000000002

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00510406

Absent
DP3a;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.000971199

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_19

Significance: 3.15649e-05

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_23

Significance: 0.0477176

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0549974

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_13

Significance: 9.211959999999999e-05

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00253978

Absent
npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.00557509

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00255834

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0001356

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.000261004

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.00237216

Absent
MegEP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00278462

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00781758

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.026712299999999998

Absent
pGMP;A;En

Pattern: metacluster_1/pattern_11

Significance: 0.0020012999999999997

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0118125

Absent
ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00155395

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00174108

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.000320133

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 4.48091e-05

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00245786

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00210276

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.041411699999999996

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00147196

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00168388

Absent
wCH12;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.0559303

Absent
CH12;med14;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.037025999999999996

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00110671

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00576895

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.00188328

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_10

Significance: 7.58322e-06

Absent
NTRPHL;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00225196

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00655503

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.027085700000000004

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.014095600000000002

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00321312

Absent
LVR;8wks;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.00492211

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0007475110000000001

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.010805799999999999

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00151132

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.05531559999999999

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0157659

Absent
ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0462651

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0295295

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0211918

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.00599626

Absent
Unique Cell types only Homer finds Mafg: #28

Cell typeModiscoHomer
STMCH;P0;D;EnAbsent

Pattern: motif6.motif

Significance: 0.0490592

MCRPHG_BMD.LPD_Stmltd;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0217103

BSPHL;A;CLAbsent

Pattern: motif3.motif

Significance: 0.00735854

DC_LPS;2h;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.00137854

MTR_NRN_MN1;methyl3;D;EnAbsent

Pattern: motif2.motif

Significance: 0.0282322

BCK_SKN;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.0559336

eCortical_NRN;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0542778

ES;MEF;A;CLAbsent

Pattern: motif1.motif

Significance: 0.05379

Adrenal;A;CLAbsent

Pattern: motif1.motif

Significance: 0.0125256

Mammary_BptfKO;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.027419799999999998

BRN;OLFTRY_BLB;A;CLAbsent

Pattern: motif1.motif

Significance: 0.013865

BRN;FRNTL_CRTX;A;CLAbsent

Pattern: motif7.motif

Significance: 0.05672340000000001

BRN;SNSR_MTR_CRTX;A;CLAbsent

Pattern: motif1.motif

Significance: 0.0439784

T_SPLND_blstCLTRD;CD4+;D;GEOAbsent

Pattern: motif14.motif

Significance: 0.0411083

gamma_delta_TCR_M-S-;A;CLAbsent

Pattern: motif11.motif

Significance: 0.0460639

NCR+ILC3;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0134761

ILC2_Nippo;A;CLAbsent

Pattern: motif7.motif

Significance: 0.016896

416B_MP;CD34+;D;GEOAbsent

Pattern: motif3.motif

Significance: 0.0161707

NCR+ILC3+IL23;A;CLAbsent

Pattern: motif3.motif

Significance: 0.00951923

WHL_BRN;8wks;D;GEOAbsent

Pattern: motif3.motif

Significance: 0.0280057

aB_LPS+IL4+Oligomycin_24h;A;CLAbsent

Pattern: motif16.motif

Significance: 0.0462535

FBRBLST;8wks;D;EnAbsent

Pattern: motif1.motif

Significance: 0.0102264

wCH12_drug;A;CLAbsent

Pattern: motif19.motif

Significance: 0.0130711

3T3-L1;FBRBLST;D;EnAbsent

Pattern: motif2.motif

Significance: 0.0175982

Mammary_GLND;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.00631311

ILC1;A;GEOAbsent

Pattern: motif16.motif

Significance: 0.0376569

Muller;P12;D;EnAbsent

Pattern: motif1.motif

Significance: 0.01024

WHL_BRN;8wks;D;EnAbsent

Pattern: motif4.motif

Significance: 0.020016