In [1]:
# Parameters
data_name = "Mef2a"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:19:22,962 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Mef2a: Motif: M09599_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Mef2a: #21

Cell typeModiscoHomer
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 6.88883e-05

Pattern: motif4.motif

Significance: 2.72062e-05

plasmaB;A;CL

Pattern: metacluster_1/pattern_11

Significance: 7.429890000000001e-05

Pattern: motif18.motif

Significance: 0.000278677

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.000144735

Pattern: motif17.motif

Significance: 0.0006137769999999999

MCRPHG;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00043209300000000004

Pattern: motif18.motif

Significance: 0.000376064

ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 3.88473e-06

Pattern: motif5.motif

Significance: 9.67359e-05

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 2.6387099999999997e-06

Pattern: motif2.motif

Significance: 4.4090400000000004e-07

eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 3.7500699999999995e-06

Pattern: motif5.motif

Significance: 6.31829e-06

Muscle;A;CL

Pattern: metacluster_1/pattern_1

Significance: 9.065049999999999e-05

Pattern: motif1.motif

Significance: 0.000141802

Heart;D;En

Pattern: metacluster_0/pattern_4

Significance: 2.3401e-05

Pattern: motif2.motif

Significance: 5.12191e-06

BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_8

Significance: 2.1901e-05

Pattern: motif7.motif

Significance: 0.05701669999999999

/

Pattern: motif14.motif

Significance: 0.000138811

BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_3

Significance: 6.81559e-07

Pattern: motif12.motif

Significance: 1.3206799999999998e-06

BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_6

Significance: 3.5868699999999995e-06

Pattern: motif6.motif

Significance: 2.22855e-06

BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_2

Significance: 6.071810000000001e-06

Pattern: motif3.motif

Significance: 1.50298e-08

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 5.565409999999999e-06

Pattern: motif5.motif

Significance: 3.2538400000000003e-06

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_16

Significance: 7.36932e-05

Pattern: motif19.motif

Significance: 0.000955647

LNG;P0;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.000115486

Pattern: motif21.motif

Significance: 0.0182732

Heart;8wks;D;En

Pattern: metacluster_0/pattern_5

Significance: 6.00483e-05

Pattern: motif3.motif

Significance: 9.49607e-06

Heart;P0;D;En

Pattern: metacluster_1/pattern_1

Significance: 5.98951e-05

Pattern: motif2.motif

Significance: 1.37952e-05

CRBLM;D;En

Pattern: metacluster_1/pattern_11

Significance: 8.952799999999999e-05

Pattern: motif12.motif

Significance: 1.71804e-05

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 1.3291400000000001e-05

Pattern: motif5.motif

Significance: 2.34925e-08

wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_2

Significance: 8.79833e-06

Pattern: motif3.motif

Significance: 2.2680999999999998e-07

Unique Cell types only TF-MoDISco finds Mef2a: #112

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_26

Significance: 0.000832214

Absent
NK_SPLND;A;CL

Pattern: metacluster_0/pattern_20

Significance: 9.84835e-05

Absent
preB;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.000212108

Absent
immatureB;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.000581955

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_20

Significance: 0.00031820599999999997

Absent
GC_B;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.000174119

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.000307572

Absent
aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_18

Significance: 6.29787e-05

Absent
aB_LPS+IL21;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.000277163

Absent
aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_23

Significance: 0.000274584

Absent
aB_CD40+IL4;A;CL

Pattern: metacluster_1/pattern_16

Significance: 9.63438e-05

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_25

Significance: 0.00028936799999999997

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.000182749

Absent
naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.000123328

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00026416

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_17

Significance: 5.8331099999999995e-05

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_18

Significance: 5.01379e-05

Absent
CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C

Pattern: metacluster_1/pattern_15

Significance: 9.075600000000001e-05

Absent
CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00728116

Absent
CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_16

Significance: 7.53842e-05

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0001294

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.0007556630000000001

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.000429749

Absent
DP;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.000203157

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00031978299999999997

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00023003700000000002

Absent
Adrenal;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00021113799999999998

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_21

Significance: 9.02344e-05

Absent
STMCH;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.022892

/

Pattern: metacluster_1/pattern_21

Significance: 0.017035599999999998

Absent
eye-NRL_RTN;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.00031957400000000004

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.00033118599999999997

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00200781

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_16

Significance: 3.10715e-05

Absent
restingB;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00039632400000000004

Absent
aB;CD180;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.000147419

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.000190128

Absent
gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00011794899999999999

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.00204261

Absent
NK;IL2+IL12+;A;CL

Pattern: metacluster_1/pattern_16

Significance: 7.27861e-05

Absent
ILC1;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.000265645

Absent
NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_22

Significance: 0.000439663

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.000209344

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_19

Significance: 0.000328371

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.000175849

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00010029999999999998

Absent
wCH12;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00062512

/

Pattern: metacluster_1/pattern_23

Significance: 0.00036842900000000003

Absent
CH12;med14;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.000118275

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_15

Significance: 6.04974e-05

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.000290142

Absent
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.000298428

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.000202848

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0419835

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00022655

Absent
T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.000260696

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_22

Significance: 0.000397344

Absent
T_MLD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00035339800000000005

Absent
T_MLD;TCR_SV40-I_CD8+;D60;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00020967599999999998

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.000167675

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.00025482

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.000240925

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00012346

Absent
prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.000178958

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00018134599999999998

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.000217415

Absent
DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00021495799999999998

Absent
DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00034679999999999997

Absent
ROD_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.000260364

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.000154466

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.000159225

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.000163606

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_24

Significance: 9.65709e-05

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.000116966

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.000114318

Absent
NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.000243165

Absent
NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 7.328180000000001e-05

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 2.50281e-05

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.00018019

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.00013413799999999998

Absent
MegP;A;En

Pattern: metacluster_1/pattern_23

Significance: 0.0005096969999999999

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.000469412

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_16

Significance: 0.00015861100000000002

Absent
NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.000186578

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.00014429299999999998

Absent
3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_23

Significance: 0.00116339

Absent
416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_22

Significance: 0.000528728

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.000128295

Absent
3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.000285891

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.000202807

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_15

Significance: 8.00228e-05

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 8.25807e-05

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.000289477

Absent
Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.000211262

Absent
RTN;D1;D;En

Pattern: metacluster_0/pattern_23

Significance: 0.000367427

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.000153181

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.000254644

Absent
Muller;P12;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.000527355

/

Pattern: metacluster_1/pattern_23

Significance: 9.92815e-05

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.000168345

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.000198113

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.00024719900000000003

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_26

Significance: 0.000784636

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.000280969

Absent
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_21

Significance: 0.000381285

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 7.6277e-05

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_22

Significance: 0.000349931

Absent
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_21

Significance: 0.00028093

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.000297498

Absent
AML;D;En

Pattern: metacluster_1/pattern_21

Significance: 0.000392559

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.000234761

Absent
NIH3T3;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.000362897

/

Pattern: metacluster_1/pattern_24

Significance: 0.000263862

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_24

Significance: 0.000339899

Absent
MN1;D;En

Pattern: metacluster_1/pattern_21

Significance: 0.00024471

Absent
3T3-L1;D;En

Pattern: metacluster_1/pattern_22

Significance: 0.000278937

Absent
No Cell types only Homer finds Mef2a