# Parameters
data_name = "ILC1;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_84-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_84-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:59:21,648 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	ILC1
Cell Group	Other Immune Cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	108852	89328	12.2037	47688263	12628443	0.2649	7896063	0.1656	15752474	0.3305

Modelling Metadata

Metric	Value
auPRC	0.5858
Calibrated Recall at 50% FDR	0.207
Number of Positive Examples in Test Data	108114
Number of Negative Examples in Test Data	7962737
Imbalance Ratio in Test Data	0.0134
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #18

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 6470 SequenceContrib ScoresHyp_Contrib Scores	Ets1, Erg, Elk1, Gabpa, Etv2, Fli1, Elk4, Etv4, Spi1, Etv5, Elk3, Etv6, Elf2, Elf1, Ehf, Spib, Etv3, XP_911724.4, Etv1, Fev, Elf3, Elf4, Irf8, Elf5, Irf4, Stat4, Ets2, Spdef, Spic
metacluster_1/pattern_1 # seqlets: 4211 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 2723 SequenceContrib ScoresHyp_Contrib Scores	Sp2, Sp3, Klf3, Sp4, Sp1, Klf4, Klf6, E2f4, Sp5, Klf5, Klf7, Egr1, Zbtb17, Klf8, Klf12, Wt1, Egr2, Zfp281, Klf1, Maz, E2f1, Klf15
metacluster_1/pattern_3 # seqlets: 1706 SequenceContrib ScoresHyp_Contrib Scores	Atf7, Atf1, Atf2, Creb1, Creb5, Jdp2, Crem, Tfec, Srebf1, Dbp, Nfil3, Bhlhe40, Rxrb, Jun, Hlf, Mitf, Usf1, Tef, Mlx, Atf3, Tfe3, Cebpb, Mafb, Cebpa, Creb3l2, Usf2, Srebf2, Xbp1, Fosl2, Fosl1, Gmeb2, Tfeb
metacluster_1/pattern_4 # seqlets: 1641 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Runx3, Cbfb, Gfi1b
metacluster_1/pattern_5 # seqlets: 1537 SequenceContrib ScoresHyp_Contrib Scores	Irf1, Irf2, Irf7, Stat1, Prdm1, Stat2, Irf9, Irf3, Batf3
metacluster_1/pattern_6 # seqlets: 1285 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_7 # seqlets: 1156 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_8 # seqlets: 949 SequenceContrib ScoresHyp_Contrib Scores	Jund, Junb, Fos, Fosb, Batf, Bach2, Bach1, Nfe2l2, Nfe2, Mafa
metacluster_1/pattern_9 # seqlets: 785 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfx, Rfx1, Zfp42, Mxi1
metacluster_1/pattern_10 # seqlets: 673 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_11 # seqlets: 405 SequenceContrib ScoresHyp_Contrib Scores	Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_12 # seqlets: 336 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_13 # seqlets: 229 SequenceContrib ScoresHyp_Contrib Scores	Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_14 # seqlets: 101 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33
metacluster_1/pattern_15 # seqlets: 51 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 44 SequenceContrib ScoresHyp_Contrib Scores	Nfia, Nfib, Nfic
metacluster_1/pattern_17 # seqlets: 35 SequenceContrib ScoresHyp_Contrib Scores	Mef2d, Mef2a, Mef2c

Click here for Motifs by TF-MoDISco: #141

TF Name	Pattern(s)
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.002159 metacluster_1/pattern_12 0.00867142
Erg	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00223667 metacluster_1/pattern_12 0.0364481
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00256978
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 8.43939e-05 metacluster_1/pattern_12 0.00867142
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00232056 metacluster_1/pattern_12 0.0280522
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00301379
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0546398 metacluster_1/pattern_12 0.0280522
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000772624
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00268474
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00201005 metacluster_1/pattern_12 0.0280522
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0121572 metacluster_1/pattern_12 0.0549746
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00185188
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0203426 metacluster_1/pattern_12 0.05839199999999999
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00201005 metacluster_1/pattern_5 0.00287735
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00253927
Fev	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00256978
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0374041 metacluster_1/pattern_12 0.0286768
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00720857
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0195791 metacluster_1/pattern_5 1.85999e-05
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.043294400000000004 metacluster_1/pattern_12 0.0280522
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0200542 metacluster_1/pattern_5 0.00751771
Stat4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0203426
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0314111 metacluster_1/pattern_12 0.0549746
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_0 0.032963400000000004
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0360606
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 1.5059699999999999e-15 metacluster_1/pattern_15 0.049149
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 7.78617e-08 metacluster_1/pattern_15 0.029287099999999996
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.2368600000000001e-08 metacluster_1/pattern_9 6.36376e-05 metacluster_1/pattern_15 0.0009366530000000001
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.75712e-08 metacluster_1/pattern_9 0.0038905000000000003 metacluster_1/pattern_14 0.038393199999999995 metacluster_1/pattern_15 0.0020778000000000003
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 2.58772e-07 metacluster_1/pattern_9 0.0453961 metacluster_1/pattern_15 0.0153585
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00138955 metacluster_1/pattern_9 0.0453961
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000769747 metacluster_1/pattern_9 0.0038905000000000003 metacluster_1/pattern_15 0.00761528
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00134479
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000522683
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000522683
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000851427
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00121073
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00121073
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.021194400000000002
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00134479 metacluster_1/pattern_9 0.010398600000000001 metacluster_1/pattern_15 0.0172666
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00171553
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00181512
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0035704 metacluster_1/pattern_9 0.0453961
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00385194
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00729074
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0320902
Maz	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00788962
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0218085
Klf15	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0245512
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00103053
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0348968
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00110243
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.000968129
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00037591
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00390647 metacluster_1/pattern_8 0.00045648199999999997
Crem	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00415744
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00650625
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.048592199999999995
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_3 0.034508300000000006
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0348968
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0248449
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0167047
Jun	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0462502 metacluster_1/pattern_8 3.97205e-07
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0176431
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0178533
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0193628
Tef	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0196518
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_3 0.021222400000000002
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.048592199999999995 metacluster_1/pattern_8 5.25491e-06
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0588764
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0597245
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0319702
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0319702
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.036137800000000005
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.059103499999999996 metacluster_1/pattern_9 0.058329 metacluster_1/pattern_15 0.047959800000000004
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0468036
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.048592199999999995
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0508422 metacluster_1/pattern_8 9.43567e-05
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.052291899999999995 metacluster_1/pattern_8 1.8318099999999998e-06
Gmeb2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0547183
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0588764
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00012616100000000001
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00705195
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000326571
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00124566
Gfi1b	Pattern Name Modisco Significance metacluster_1/pattern_4 0.037803300000000005
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_5 8.373819999999999e-12
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00138177
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_5 1.85999e-05
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_5 1.97496e-05
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000108963
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00133486
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00133486
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00438969
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.013227200000000001
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_6 5.29365e-10
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_7 3.16085e-15
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_7 1.83364e-11
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_7 5.12086e-10
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_7 3.3988699999999994e-06
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_7 5.558969999999999e-06
Jund	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00879183
Junb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0401145
Fos	Pattern Name Modisco Significance metacluster_1/pattern_8 2.7727999999999995e-06
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_8 5.25491e-06
Batf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0218542
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00188595
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00511053
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0075623
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00602103
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0383972
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_9 3.4275800000000003e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_9 1.4483199999999999e-05
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0038905000000000003 metacluster_1/pattern_14 0.038393199999999995 metacluster_1/pattern_15 0.029287099999999996
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.010398600000000001 metacluster_1/pattern_11 4.4856599999999996e-09 metacluster_1/pattern_15 0.00761528
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0119411
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0453961 metacluster_1/pattern_15 0.049149
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 5.08061e-21
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 6.76839e-21
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 3.24185e-14
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00199802
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_11 5.5983700000000004e-08
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_11 8.0768e-05
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000964247
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00106077
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_13 3.23687e-08
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_13 4.47714e-06
Rela	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00010214399999999999
Relb	Pattern Name Modisco Significance metacluster_1/pattern_13 3.41037e-05
Rel	Pattern Name Modisco Significance metacluster_1/pattern_13 0.015144
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_14 7.2893799999999995e-06
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000970446
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00181654
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_16 0.047313
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_17 1.40203e-07
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000265645
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_17 2.11905e-07

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #66

TF Name	Modisco	Homer
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0360606	Pattern Name Homer Significance motif6.motif 0.054100999999999996
Erg	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00223667 metacluster_1/pattern_12 0.0364481	Pattern Name Homer Significance motif2.motif 0.00160255
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_5 1.97496e-05	Pattern Name Homer Significance motif6.motif 0.03842430000000001
Fev	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00256978	Pattern Name Homer Significance motif2.motif 0.000566055
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 7.78617e-08 metacluster_1/pattern_15 0.029287099999999996	Pattern Name Homer Significance motif1.motif 0.00106985
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00256978	Pattern Name Homer Significance motif2.motif 0.00160255
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00133486	Pattern Name Homer Significance motif6.motif 0.0036024
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000522683	Pattern Name Homer Significance motif3.motif 0.000611931
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000851427	Pattern Name Homer Significance motif3.motif 0.014411600000000002
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00385194	Pattern Name Homer Significance motif3.motif 0.0218267
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00729074	Pattern Name Homer Significance motif3.motif 0.05961759999999999
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329	Pattern Name Homer Significance motif2.motif 0.00182912
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0320902	Pattern Name Homer Significance motif3.motif 0.0485174
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_5 8.373819999999999e-12	Pattern Name Homer Significance motif6.motif 0.00975974
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00301379	Pattern Name Homer Significance motif2.motif 0.00176594
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_7 3.3988699999999994e-06	Pattern Name Homer Significance motif9.motif 0.00531951
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000772624	Pattern Name Homer Significance motif2.motif 0.000305468
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00121073	Pattern Name Homer Significance motif3.motif 0.0030594000000000003
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_9 1.4483199999999999e-05	Pattern Name Homer Significance motif13.motif 0.0368798
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00720857	Pattern Name Homer Significance motif2.motif 0.00888816
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0203426 metacluster_1/pattern_12 0.05839199999999999	Pattern Name Homer Significance motif2.motif 0.011495299999999998
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_5 1.85999e-05	Pattern Name Homer Significance motif6.motif 0.0533475
Klf15	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0245512	Pattern Name Homer Significance motif3.motif 0.00629265
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.002159 metacluster_1/pattern_12 0.00867142	Pattern Name Homer Significance motif2.motif 0.00160255
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 3.24185e-14	Pattern Name Homer Significance motif5.motif 5.3221800000000006e-05
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329	Pattern Name Homer Significance motif2.motif 0.00182912
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.75712e-08 metacluster_1/pattern_9 0.0038905000000000003 metacluster_1/pattern_14 0.038393199999999995 metacluster_1/pattern_15 0.0020778000000000003	Pattern Name Homer Significance motif3.motif 0.000233943
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00232056 metacluster_1/pattern_12 0.0280522	Pattern Name Homer Significance motif2.motif 0.00160255
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329	Pattern Name Homer Significance motif2.motif 0.00160255
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00134479 metacluster_1/pattern_9 0.010398600000000001 metacluster_1/pattern_15 0.0172666	Pattern Name Homer Significance motif3.motif 0.00291577
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 5.08061e-21	Pattern Name Homer Significance motif5.motif 6.8396699999999995e-06
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00138177	Pattern Name Homer Significance motif6.motif 0.00975974
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00438969	Pattern Name Homer Significance motif6.motif 0.0577249
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_9 3.4275800000000003e-06	Pattern Name Homer Significance motif13.motif 0.0368798
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000769747 metacluster_1/pattern_9 0.0038905000000000003 metacluster_1/pattern_15 0.00761528	Pattern Name Homer Significance motif3.motif 0.00187252
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_0 0.032963400000000004	Pattern Name Homer Significance motif2.motif 0.0213016
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_7 5.558969999999999e-06	Pattern Name Homer Significance motif9.motif 0.013095500000000001
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 1.5059699999999999e-15 metacluster_1/pattern_15 0.049149	Pattern Name Homer Significance motif1.motif 0.000583993
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.2368600000000001e-08 metacluster_1/pattern_9 6.36376e-05 metacluster_1/pattern_15 0.0009366530000000001	Pattern Name Homer Significance motif3.motif 0.000249675
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00201005 metacluster_1/pattern_12 0.0280522	Pattern Name Homer Significance motif2.motif 0.00302058
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00134479	Pattern Name Homer Significance motif3.motif 0.008107099999999999
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 2.58772e-07 metacluster_1/pattern_9 0.0453961 metacluster_1/pattern_15 0.0153585	Pattern Name Homer Significance motif3.motif 9.765469999999999e-05
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00133486	Pattern Name Homer Significance motif6.motif 0.0339208
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 6.76839e-21	Pattern Name Homer Significance motif5.motif 6.8396699999999995e-06
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00185188	Pattern Name Homer Significance motif2.motif 0.00115644
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 8.43939e-05 metacluster_1/pattern_12 0.00867142	Pattern Name Homer Significance motif2.motif 2.68355e-05
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00181512	Pattern Name Homer Significance motif3.motif 0.00629255
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000522683	Pattern Name Homer Significance motif3.motif 0.000249675
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_7 5.12086e-10	Pattern Name Homer Significance motif9.motif 4.4852600000000005e-05
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00268474	Pattern Name Homer Significance motif2.motif 0.00144303
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_6 5.29365e-10	Pattern Name Homer Significance motif11.motif 5.0665100000000004e-05
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0546398 metacluster_1/pattern_12 0.0280522	Pattern Name Homer Significance motif2.motif 0.00942
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00201005 metacluster_1/pattern_5 0.00287735	Pattern Name Homer Significance motif2.motif 0.0410921
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0200542 metacluster_1/pattern_5 0.00751771	Pattern Name Homer Significance motif6.motif 0.054062099999999995
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0121572 metacluster_1/pattern_12 0.0549746	Pattern Name Homer Significance motif2.motif 0.0146135
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_7 1.83364e-11	Pattern Name Homer Significance motif9.motif 0.00036852900000000004
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00233329	Pattern Name Homer Significance motif2.motif 0.00160255
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00253927	Pattern Name Homer Significance motif2.motif 0.00164913
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_7 3.16085e-15	Pattern Name Homer Significance motif9.motif 3.5482800000000005e-05
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.043294400000000004 metacluster_1/pattern_12 0.0280522	Pattern Name Homer Significance motif2.motif 0.055035400000000005
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00171553	Pattern Name Homer Significance motif3.motif 9.518950000000001e-05
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00138955 metacluster_1/pattern_9 0.0453961	Pattern Name Homer Significance motif3.motif 0.0025247
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.021194400000000002	Pattern Name Homer Significance motif3.motif 0.00709088
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00121073	Pattern Name Homer Significance motif3.motif 5.1929700000000005e-05
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0218085	Pattern Name Homer Significance motif3.motif 0.00227397
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0374041 metacluster_1/pattern_12 0.0286768	Pattern Name Homer Significance motif2.motif 0.052100099999999996

Unique TF-MoDISco TFs: #75

TF Name	Modisco	Homer
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0319702	Absent
Maz	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00788962	Absent
Stat4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0203426	Absent
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.052291899999999995 metacluster_1/pattern_8 1.8318099999999998e-06	Absent
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0119411	Absent
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00181654	Absent
Fos	Pattern Name Modisco Significance metacluster_1/pattern_8 2.7727999999999995e-06	Absent
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00012616100000000001	Absent
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0348968	Absent
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00103053	Absent
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.000968129	Absent
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_17 2.11905e-07	Absent
Relb	Pattern Name Modisco Significance metacluster_1/pattern_13 3.41037e-05	Absent
Junb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0401145	Absent
Rel	Pattern Name Modisco Significance metacluster_1/pattern_13 0.015144	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0468036	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0588764	Absent
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0348968	Absent
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_3 0.034508300000000006	Absent
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_14 7.2893799999999995e-06	Absent
Batf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0218542	Absent
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_8 5.25491e-06	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00650625	Absent
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0383972	Absent
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.048592199999999995	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0248449	Absent
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0319702	Absent
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0597245	Absent
Jund	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00879183	Absent
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0178533	Absent
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0176431	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_11 5.5983700000000004e-08	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00106077	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_3 0.021222400000000002	Absent
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.036137800000000005	Absent
Crem	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00415744	Absent
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000265645	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.048592199999999995	Absent
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00602103	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000964247	Absent
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0193628	Absent
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0508422 metacluster_1/pattern_8 9.43567e-05	Absent
Jun	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0462502 metacluster_1/pattern_8 3.97205e-07	Absent
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00110243	Absent
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0167047	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0038905000000000003 metacluster_1/pattern_14 0.038393199999999995 metacluster_1/pattern_15 0.029287099999999996	Absent
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00124566	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0035704 metacluster_1/pattern_9 0.0453961	Absent
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00037591	Absent
Rela	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00010214399999999999	Absent
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0588764	Absent
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_16 0.047313	Absent
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.059103499999999996 metacluster_1/pattern_9 0.058329 metacluster_1/pattern_15 0.047959800000000004	Absent
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00188595	Absent
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_3 0.048592199999999995 metacluster_1/pattern_8 5.25491e-06	Absent
Gfi1b	Pattern Name Modisco Significance metacluster_1/pattern_4 0.037803300000000005	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000970446	Absent
Gmeb2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0547183	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.010398600000000001 metacluster_1/pattern_11 4.4856599999999996e-09 metacluster_1/pattern_15 0.00761528	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_11 8.0768e-05	Absent
Tef	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0196518	Absent
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000108963	Absent
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000326571	Absent
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_13 4.47714e-06	Absent
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00390647 metacluster_1/pattern_8 0.00045648199999999997	Absent
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0075623	Absent
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_17 1.40203e-07	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_11 0.00199802	Absent
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0195791 metacluster_1/pattern_5 1.85999e-05	Absent
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00705195	Absent
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00511053	Absent
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0453961 metacluster_1/pattern_15 0.049149	Absent
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_13 3.23687e-08	Absent
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.013227200000000001	Absent
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0314111 metacluster_1/pattern_12 0.0549746	Absent

Unique Homer TFs: #4

TF Name	Modisco	Homer
E2f6	Absent	Pattern Name Homer Significance motif3.motif 0.017912099999999997
Egr3	Absent	Pattern Name Homer Significance motif3.motif 0.05961759999999999
E2f7	Absent	Pattern Name Homer Significance motif3.motif 0.00681544
Zbtb1	Absent	Pattern Name Homer Significance motif3.motif 0.013466299999999999