In [1]:
# Parameters
data_name = "Mlxip"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:20:15,113 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Mlxip: Motif: M01743_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Mlxip: #6

Cell typeModiscoHomer
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0577565

Pattern: motif13.motif

Significance: 0.0407379

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.0489014

Pattern: motif13.motif

Significance: 0.056453699999999996

B_SPLND;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0550773

Pattern: motif21.motif

Significance: 0.023086000000000002

LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0532317

Pattern: motif5.motif

Significance: 0.0546135

Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.055489199999999995

Pattern: motif16.motif

Significance: 0.041237699999999995

Heart;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.059226

Pattern: motif14.motif

Significance: 0.0386711

Unique Cell types only TF-MoDISco finds Mlxip: #122

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_10

Significance: 0.050427099999999996

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0536624

Absent
NK_SPLND;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0555504

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.057183300000000006

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0585219

Absent
aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0537062

Absent
aB_LPS+IL21;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0559956

Absent
aB_CD40+IL4;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.05213480000000001

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0596068

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_10

Significance: 0.051409699999999996

Absent
NTRPHL;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.04810759999999999

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0585719

Absent
naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.052281600000000004

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0559437

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.058016

Absent
CD4+CD8intTCR+CD69+CD24+;MHC2defM;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0566058

Absent
CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C

Pattern: metacluster_1/pattern_8

Significance: 0.052286599999999996

Absent
CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0546009

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.055824900000000004

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.051038400000000005

Absent
DP3a;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0483305

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0552982

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.054218499999999996

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_15

Significance: 0.0516757

Absent
Adipose;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0546534

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.058339199999999994

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.048001199999999994

Absent
eye-NRL_RTN;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0524264

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0464517

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.042329000000000006

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0435385

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0490742

Absent
restingB;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.049834300000000005

Absent
aB;CD180;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.047719199999999996

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.052001099999999995

Absent
gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.052986

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0545135

Absent
NK;IL2+IL12+;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0522184

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.0514411

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_10

Significance: 0.051255600000000005

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0453575

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0543665

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.05833819999999999

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.050416300000000004

Absent
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.054130700000000004

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0475505

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.048446699999999995

Absent
ILC1;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0538144

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0543259

Absent
Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.057844799999999995

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.057911199999999996

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.058163

Absent
prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.0563621

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.053350800000000004

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0568168

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.054750400000000005

Absent
MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0532361

Absent
Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0548564

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.05776569999999999

Absent
DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.052512800000000005

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0502455

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.059165199999999994

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.046893300000000006

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.056494600000000006

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.053764

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.049069699999999994

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0435661

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.041106199999999996

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0548567

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0484606

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0371879

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.058347

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.047715600000000004

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.050901800000000004

Absent
npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0559648

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.0489152

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0579928

Absent
MegP;A;En

Pattern: metacluster_1/pattern_11

Significance: 0.0550805

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0586317

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.059605099999999994

Absent
ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.055968

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.048726

Absent
NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.044927499999999995

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0565894

Absent
T_SPLND_blstCLTRD;CD4+;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0530683

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.052569000000000005

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.047414599999999994

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.047378500000000004

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0448798

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0556141

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0462437

Absent
3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0540569

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.048697000000000004

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.035758099999999994

Absent
LVR;8wks;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.057149

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_11

Significance: 0.0585365

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0557751

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.038331699999999996

Absent
LNG;P0;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.048226

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.045438599999999996

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.052245299999999995

Absent
RTN;D1;D;En

Pattern: metacluster_0/pattern_14

Significance: 0.046321100000000004

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_20

Significance: 0.053934

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.0571044

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0411899

Absent
Muller;P12;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.056007600000000005

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0490523

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.0596355

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0492812

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.0596395

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0510172

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0310594

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.056155

Absent
wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0546022

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0592337

Absent
LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.059486300000000006

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0396681

Absent
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0493474

Absent
Spleen;8wks;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.052456600000000006

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0472851

Absent
NIH3T3;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.054424400000000005

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_19

Significance: 0.0566491

Absent
Unique Cell types only Homer finds Mlxip: #10

Cell typeModiscoHomer
largeDPprecrsr;CD4+CD8+CD69-;A;CLAbsent

Pattern: motif18.motif

Significance: 0.0420829

wES;Fr_lmb;E11.5;D;EnAbsent

Pattern: motif20.motif

Significance: 0.0459766

ES;F1216;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.0369668

DC;A;EnAbsent

Pattern: motif13.motif

Significance: 0.0480696

MCRPHG;A;CLAbsent

Pattern: motif6.motif

Significance: 0.054835300000000003

A20;B-lymphoma;D;EnAbsent

Pattern: motif13.motif

Significance: 0.010257299999999999

DP;A;CLAbsent

Pattern: motif17.motif

Significance: 0.039338599999999994

ISP;A;CLAbsent

Pattern: motif14.motif

Significance: 0.041265699999999995

/

Pattern: motif22.motif

Significance: 0.058433900000000004

DC_LPS;6h;A;GEOAbsent

Pattern: motif12.motif

Significance: 0.0456531

wES;Md_BRN;E11.5;D;EnAbsent

Pattern: motif22.motif

Significance: 0.0475493