In [1]:
# Parameters
data_name = "Maf"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:18:30,338 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Maf: Motif: M08839_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Maf: #27

Cell typeModiscoHomer
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0450045

Pattern: motif1.motif

Significance: 0.0223053

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0343894

Pattern: motif3.motif

Significance: 0.00183497

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0477456

Pattern: motif3.motif

Significance: 0.0566764

Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00379413

Pattern: motif19.motif

Significance: 0.000332155

AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00333799

Pattern: motif15.motif

Significance: 0.0005185

MEF.GATA-1-ER;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00538894

Pattern: motif23.motif

Significance: 0.00067673

NIH3T3;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0269115

Pattern: motif2.motif

Significance: 0.029676400000000002

3T3-L1;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.035549800000000006

Pattern: motif1.motif

Significance: 0.013293700000000002

npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.031965

Pattern: motif15.motif

Significance: 0.054495400000000006

MCRPHG;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0296281

Pattern: motif3.motif

Significance: 0.00404352

Erythroblast;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00290288

Pattern: motif19.motif

Significance: 0.017098500000000003

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.021889

/

Pattern: metacluster_1/pattern_10

Significance: 1.29393e-07

Pattern: motif7.motif

Significance: 0.0199348

EPP;A;En

Pattern: metacluster_1/pattern_12

Significance: 0.00288025

Pattern: motif21.motif

Significance: 0.00318701

pErythroblast;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.0043329

Pattern: motif16.motif

Significance: 0.046706300000000006

MegP;A;En

Pattern: metacluster_1/pattern_8

Significance: 0.00361343

Pattern: motif15.motif

Significance: 0.00803526

pCMP;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.00374238

Pattern: motif12.motif

Significance: 0.01646

DC;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.0473136

Pattern: motif3.motif

Significance: 0.00753353

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00270037

Pattern: motif26.motif

Significance: 0.000411395

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00966191

Pattern: motif2.motif

Significance: 0.0240363

3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_0

Significance: 0.042944300000000005

Pattern: motif1.motif

Significance: 0.019131400000000003

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0489433

Pattern: motif2.motif

Significance: 0.0510328

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_13

Significance: 0.00324819

Pattern: motif17.motif

Significance: 0.00965684

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00409651

Pattern: motif15.motif

Significance: 0.0466146

Adipose;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0380615

Pattern: motif14.motif

Significance: 0.039324300000000006

EP;c-kit+CD71+Ter119+;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00395443

Pattern: motif16.motif

Significance: 0.00497193

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.012262799999999999

Pattern: motif4.motif

Significance: 0.00302298

T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0592947

Pattern: motif18.motif

Significance: 0.058282900000000006

Unique Cell types only TF-MoDISco finds Maf: #69

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00348686

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.049303

Absent
proB;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00674799

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.037313

Absent
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0176942

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00810399

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.018482

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.00838407

Absent
AML;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00260292

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.046854

Absent
MEL;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0027603000000000003

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0059895

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00285953

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_9

Significance: 0.00598836

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_9

Significance: 0.0219362

Absent
NTRPHL;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.044366300000000004

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.050977800000000004

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.030817700000000003

Absent
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.011865700000000002

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.052266999999999994

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.057941099999999995

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_28

Significance: 0.052194000000000004

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00155841

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0432151

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0310365

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.014966

Absent
DP3a;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00128097

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_19

Significance: 8.365e-05

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_23

Significance: 0.00808564

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.000122771

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00371195

Absent
npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.00848008

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0035586

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.000515751

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00046908199999999995

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.00323815

Absent
MegEP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00386084

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.010324

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.0341863

Absent
pGMP;A;En

Pattern: metacluster_1/pattern_11

Significance: 0.00320859

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.013622899999999999

Absent
ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00186305

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00276148

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.000851938

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00040637

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00358278

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0029006

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.0432555

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00227028

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00253157

Absent
wCH12;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.0518757

Absent
CH12;med14;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0575552

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00170742

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00693319

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.00296721

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_10

Significance: 6.91433e-05

Absent
NTRPHL;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00257975

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00792772

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0298282

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.0379755

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00776373

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.016083

Absent
LVR;8wks;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.00713199

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0010488

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0148079

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.025704200000000003

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0237488

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0319477

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.00732259

Absent
Unique Cell types only Homer finds Maf: #24

Cell typeModiscoHomer
MCRPHG_BMD.LPD_Stmltd;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.05152

BSPHL;A;CLAbsent

Pattern: motif3.motif

Significance: 0.00735854

DC_LPS;2h;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.00235876

MN1;D;EnAbsent

Pattern: motif3.motif

Significance: 0.0492029

MTR_NRN_MN1;methyl3;D;EnAbsent

Pattern: motif2.motif

Significance: 0.057108400000000004

Adrenal;A;CLAbsent

Pattern: motif1.motif

Significance: 0.015582599999999999

Mammary_BptfKO;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.037096

BRN;OLFTRY_BLB;A;CLAbsent

Pattern: motif1.motif

Significance: 0.036396

BRN;FRNTL_CRTX;A;CLAbsent

Pattern: motif7.motif

Significance: 0.057255099999999996

BRN;SNSR_MTR_CRTX;A;CLAbsent

Pattern: motif1.motif

Significance: 0.0505743

gamma_delta_TCR;A;CLAbsent

Pattern: motif13.motif

Significance: 0.02883

NCR+ILC3;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0201879

ILC2_Nippo;A;CLAbsent

Pattern: motif7.motif

Significance: 0.033467199999999996

416B_MP;CD34+;D;GEOAbsent

Pattern: motif3.motif

Significance: 0.023221900000000004

NCR+ILC3+IL23;A;CLAbsent

Pattern: motif3.motif

Significance: 0.027512400000000003

WHL_BRN;8wks;D;GEOAbsent

Pattern: motif3.motif

Significance: 0.036434100000000004

aB_LPS+IL4+Oligomycin_24h;A;CLAbsent

Pattern: motif16.motif

Significance: 0.0450632

FBRBLST;8wks;D;EnAbsent

Pattern: motif1.motif

Significance: 0.026382299999999997

wCH12_drug;A;CLAbsent

Pattern: motif19.motif

Significance: 0.0226155

3T3-L1;FBRBLST;D;EnAbsent

Pattern: motif2.motif

Significance: 0.0296493

Mammary_GLND;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.0202674

ILC1;A;GEOAbsent

Pattern: motif16.motif

Significance: 0.0498513

Muller;P12;D;EnAbsent

Pattern: motif1.motif

Significance: 0.0302837

WHL_BRN;8wks;D;EnAbsent

Pattern: motif4.motif

Significance: 0.043396699999999996