In [1]:
# Parameters
data_name = "Maff"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:18:42,543 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Maff: Motif: M08834_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Maff: #22

Cell typeModiscoHomer
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0326484

Pattern: motif3.motif

Significance: 0.000907956

AML;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00339456

Pattern: motif13.motif

Significance: 0.052482100000000004

Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00260386

Pattern: motif19.motif

Significance: 2.86518e-05

AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00333799

Pattern: motif15.motif

Significance: 0.000352846

MEF.GATA-1-ER;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00491845

Pattern: motif23.motif

Significance: 0.000510625

NIH3T3;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.047249599999999996

Pattern: motif2.motif

Significance: 0.0209851

3T3-L1;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.052297300000000005

Pattern: motif1.motif

Significance: 0.0125199

MCRPHG;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0297733

Pattern: motif3.motif

Significance: 0.00260117

Erythroblast;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00246156

Pattern: motif19.motif

Significance: 0.012829499999999999

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.028910500000000002

/

Pattern: metacluster_1/pattern_10

Significance: 8.121989999999999e-06

Pattern: motif7.motif

Significance: 0.023402799999999998

EPP;A;En

Pattern: metacluster_1/pattern_12

Significance: 0.00174608

Pattern: motif21.motif

Significance: 0.00229031

pErythroblast;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.00397282

Pattern: motif16.motif

Significance: 0.0294

MegP;A;En

Pattern: metacluster_1/pattern_8

Significance: 0.00338136

Pattern: motif15.motif

Significance: 0.00192767

pCMP;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.00345685

Pattern: motif12.motif

Significance: 0.01646

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00187532

Pattern: motif26.motif

Significance: 0.000187396

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00801881

Pattern: motif2.motif

Significance: 0.012787

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_13

Significance: 0.00324819

Pattern: motif17.motif

Significance: 0.00825912

ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00788488

Pattern: motif3.motif

Significance: 0.0128155

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00442694

Pattern: motif15.motif

Significance: 0.036808999999999995

Adipose;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0402436

Pattern: motif14.motif

Significance: 0.0354259

EP;c-kit+CD71+Ter119+;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00365281

Pattern: motif16.motif

Significance: 0.00247699

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0143149

Pattern: motif4.motif

Significance: 0.00198898

Unique Cell types only TF-MoDISco finds Maff: #65

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00286908

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0330735

Absent
proB;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00674799

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_21

Significance: 0.0442885

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0336595

Absent
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0195165

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00810399

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0158607

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.00444361

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0554436

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.0208204

Absent
MEL;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00248318

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0059895

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00154439

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_9

Significance: 0.00655852

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_9

Significance: 0.0219362

Absent
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00452978

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0376026

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0407906

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0433221

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_28

Significance: 0.0456094

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.000562032

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0222166

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00724076

Absent
DP3a;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.000971199

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_19

Significance: 7.599810000000001e-05

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.000122771

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00279783

Absent
npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.00848008

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00307527

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.000218586

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.000367365

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.00244593

Absent
MegEP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00281736

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.0116652

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.0341863

Absent
pGMP;A;En

Pattern: metacluster_1/pattern_11

Significance: 0.0020012999999999997

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0186019

Absent
ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00156418

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00225081

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.000336753

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 4.76268e-05

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0024889

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00245828

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.0132854

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.0432555

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00147196

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00177213

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00111357

Absent
CH12;med14;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.047649199999999996

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.0021582

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00734969

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_10

Significance: 7.58322e-06

Absent
LVR;8wks;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.00424256

Absent
NTRPHL;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00250675

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00792772

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.035840199999999996

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.0190632

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00462386

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.000930438

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0148079

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0316033

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0202995

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.038881099999999995

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.00918248

Absent
Unique Cell types only Homer finds Maff: #30

Cell typeModiscoHomer
3134_mammaryADNCRCNM;D;EnAbsent

Pattern: motif1.motif

Significance: 0.0284053

MCRPHG_BMD.LPD_Stmltd;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0123345

BSPHL;A;CLAbsent

Pattern: motif3.motif

Significance: 0.00900216

DC_LPS;2h;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.00235876

MTR_NRN_MN1;methyl3;D;EnAbsent

Pattern: motif2.motif

Significance: 0.0379659

MN1;D;EnAbsent

Pattern: motif3.motif

Significance: 0.042494699999999996

Adrenal;A;CLAbsent

Pattern: motif1.motif

Significance: 0.0162816

Mammary_BptfKO;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.031390499999999995

BRN;OLFTRY_BLB;A;CLAbsent

Pattern: motif1.motif

Significance: 0.018614099999999998

DC;A;EnAbsent

Pattern: motif3.motif

Significance: 0.00657048

3134_mammaryADNCRCNM;D;GEAbsent

Pattern: motif1.motif

Significance: 0.0132856

gamma_delta_TCR;A;CLAbsent

Pattern: motif13.motif

Significance: 0.0343181

T_SPLND_blstCLTRD;CD4+;D;GEOAbsent

Pattern: motif14.motif

Significance: 0.0494256

gamma_delta_TCR_M-S-;A;CLAbsent

Pattern: motif11.motif

Significance: 0.05600599999999999

NCR+ILC3;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0184985

ILC2_Nippo;A;CLAbsent

Pattern: motif7.motif

Significance: 0.0208599

416B_MP;CD34+;D;GEOAbsent

Pattern: motif3.motif

Significance: 0.025294999999999998

NCR+ILC3+IL23;A;CLAbsent

Pattern: motif3.motif

Significance: 0.0122659

WHL_BRN;8wks;D;GEOAbsent

Pattern: motif3.motif

Significance: 0.0391996

aB_LPS+IL4+Oligomycin_24h;A;CLAbsent

Pattern: motif16.motif

Significance: 0.0515119

NIH3T3_FBROBLST;D;EnAbsent

Pattern: motif2.motif

Significance: 0.0380536

FBRBLST;8wks;D;EnAbsent

Pattern: motif1.motif

Significance: 0.0127062

wCH12_drug;A;CLAbsent

Pattern: motif19.motif

Significance: 0.019869099999999997

3T3-L1;FBRBLST;D;EnAbsent

Pattern: motif2.motif

Significance: 0.023127599999999998

Mammary_GLND;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.0107401

ILC1;A;GEOAbsent

Pattern: motif16.motif

Significance: 0.0554129

T_LCMV;CD8+;D35;A;GEOAbsent

Pattern: motif18.motif

Significance: 0.0487108

Muller;P12;D;EnAbsent

Pattern: motif1.motif

Significance: 0.0138584

TSLEC_SPLND;CD8+A;GEOAbsent

Pattern: motif22.motif

Significance: 0.05316950000000001

WHL_BRN;8wks;D;EnAbsent

Pattern: motif4.motif

Significance: 0.024583400000000002