In [1]:
# Parameters
data_name = "Runx3"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:33:06,674 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Runx3: Motif: M09374_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Runx3: #59

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00513599

/

Pattern: metacluster_1/pattern_13

Significance: 0.034304

/

Pattern: metacluster_1/pattern_22

Significance: 0.052698

Pattern: motif3.motif

Significance: 0.015511600000000002

T_MLD;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.000130129

Pattern: motif4.motif

Significance: 0.000150707

T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 1.99712e-05

Pattern: motif4.motif

Significance: 8.0106e-08

memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0005286140000000001

Pattern: motif4.motif

Significance: 0.0225209

memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.000181867

Pattern: motif4.motif

Significance: 0.0076295

memT_tmrD_lstr;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000637485

Pattern: motif4.motif

Significance: 0.0136685

memT_tmrD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00023993

Pattern: motif4.motif

Significance: 0.000637684

iNKT;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00076953

Pattern: motif4.motif

Significance: 0.0110081

Spleen;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00221826

Pattern: motif16.motif

Significance: 0.00623105

3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.00016655900000000002

Pattern: motif5.motif

Significance: 0.00880667

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.05837180000000001

Pattern: motif4.motif

Significance: 0.009142

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00119188

Pattern: motif5.motif

Significance: 0.0158796

aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00114286

/

Pattern: metacluster_1/pattern_16

Significance: 0.051778599999999994

Pattern: motif16.motif

Significance: 0.0306272

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 2.92076e-06

Pattern: motif13.motif

Significance: 0.00215339

aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00151695

Pattern: motif12.motif

Significance: 0.0555274

Mast;A;CL

Pattern: metacluster_0/pattern_5

Significance: 1.14882e-06

Pattern: motif7.motif

Significance: 0.00020978599999999997

BSPHL;A;CL

Pattern: metacluster_1/pattern_6

Significance: 2.10611e-05

/

Pattern: metacluster_1/pattern_14

Significance: 0.0485234

Pattern: motif4.motif

Significance: 0.00543236

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_11

Significance: 1.72919e-07

Pattern: motif11.motif

Significance: 0.0575149

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00035077

Pattern: motif8.motif

Significance: 0.00400777

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.000842223

Pattern: motif7.motif

Significance: 0.010388799999999998

3T3-L1;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00739133

Pattern: motif6.motif

Significance: 0.00116278

naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0101825

Pattern: motif7.motif

Significance: 0.0517783

CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00295921

Pattern: motif11.motif

Significance: 0.0501111

CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C

Pattern: metacluster_1/pattern_10

Significance: 0.00759957

Pattern: motif5.motif

Significance: 0.0111201

CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.011014399999999999

Pattern: motif14.motif

Significance: 0.00531986

CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00999682

Pattern: motif11.motif

Significance: 0.0503539

DC_BMD;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000210278

Pattern: motif6.motif

Significance: 1.59383e-05

DP3a;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.000249468

Pattern: motif3.motif

Significance: 0.0196779

ES;MEF;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00046715900000000003

Pattern: motif6.motif

Significance: 0.0033189

pCMP;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.000455528

Pattern: motif4.motif

Significance: 0.011966899999999999

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_11

Significance: 3.73713e-05

Pattern: motif9.motif

Significance: 0.00911134

pGMP;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.00719341

/

Pattern: metacluster_1/pattern_17

Significance: 0.0124826

/

Pattern: metacluster_1/pattern_18

Significance: 0.0189743

Pattern: motif5.motif

Significance: 0.011855500000000001

DC;A;En

Pattern: metacluster_1/pattern_8

Significance: 3.04994e-05

Pattern: motif7.motif

Significance: 0.000785468

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.010808499999999999

Pattern: motif16.motif

Significance: 0.00115406

LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00172691

Pattern: motif12.motif

Significance: 0.045872699999999995

3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_12

Significance: 0.000542142

Pattern: motif5.motif

Significance: 0.0018534000000000003

naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00158397

Pattern: motif12.motif

Significance: 0.047712199999999996

NK;IL2+IL12+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 2.1709699999999996e-05

Pattern: motif3.motif

Significance: 8.613719999999999e-05

apCD4Eff;D;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00190161

Pattern: motif4.motif

Significance: 0.0224315

NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00017865400000000001

Pattern: motif3.motif

Significance: 0.0195542

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000250025

Pattern: motif4.motif

Significance: 0.00899539

NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00059672

Pattern: motif5.motif

Significance: 0.014631899999999998

CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_13

Significance: 6.992539999999999e-05

Pattern: motif18.motif

Significance: 0.0040654

wCH12;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00151686

/

Pattern: metacluster_1/pattern_21

Significance: 0.0277793

Pattern: motif15.motif

Significance: 0.00378261

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.000750838

Pattern: motif5.motif

Significance: 0.000542354

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0124114

Pattern: motif11.motif

Significance: 0.00770363

CLP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00229089

Pattern: motif3.motif

Significance: 0.00516567

mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.000150496

Pattern: motif4.motif

Significance: 0.00591601

ILC1;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 7.86243e-05

Pattern: motif4.motif

Significance: 0.00183818

ILC3;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 2.7351599999999997e-05

Pattern: motif3.motif

Significance: 0.00301741

ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00122166

Pattern: motif4.motif

Significance: 0.0407651

ILC3_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 4.04291e-06

Pattern: motif3.motif

Significance: 0.00172431

T_LCMV;CD8+;D8;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00159404

Pattern: motif4.motif

Significance: 0.00020380099999999998

Muller;P12;D;En

Pattern: metacluster_1/pattern_10

Significance: 9.497869999999999e-06

Pattern: motif5.motif

Significance: 7.52721e-05

TExh_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00056394

Pattern: motif4.motif

Significance: 0.00264975

TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00012432

Pattern: motif4.motif

Significance: 0.00111942

cntrl_memT;TCR_SV40-I_CD8+;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00103099

Pattern: motif4.motif

Significance: 0.023668099999999997

T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0008552039999999999

Pattern: motif9.motif

Significance: 0.031104400000000004

T_MLD;TCR_SV40-I_CD8+;D21;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.000652767

Pattern: motif5.motif

Significance: 0.000371621

Unique Cell types only TF-MoDISco finds Runx3: #72

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.000667658

Absent
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00292645

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00199533

Absent
NK_SPLND;A;CL

Pattern: metacluster_0/pattern_5

Significance: 0.00011180299999999999

Absent
proB;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.000320952

Absent
preB;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00152721

Absent
T_MLD;TCR_SV40-I_CD8+;D60;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.000603027

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.00282441

Absent
MZ_B;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.047051800000000005

/

Pattern: metacluster_1/pattern_10

Significance: 0.00389077

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00466792

/

Pattern: metacluster_1/pattern_17

Significance: 0.032691200000000004

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.000400995

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00286155

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00442324

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00022795200000000002

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00178675

Absent
AML;D;En

Pattern: metacluster_1/pattern_8

Significance: 4.04011e-05

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00039740800000000003

Absent
DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.000759903

/

Pattern: metacluster_1/pattern_21

Significance: 0.00437124

/

Pattern: metacluster_1/pattern_22

Significance: 5.38837e-05

Absent
MEL;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00792383

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0102417

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00545241

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00157796

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00028462400000000003

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00139056

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00276993

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_21

Significance: 0.00109678

Absent
naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.000282185

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.010580899999999999

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_13

Significance: 7.68843e-05

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00457167

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00365566

Absent
CD4+CD8intTCR+CD69+CD24+;MHC2defM;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00406148

Absent
CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00319809

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00129349

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00409875

Absent
MCRPHG;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0225185

/

Pattern: metacluster_1/pattern_18

Significance: 0.0366288

Absent
DP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00149436

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00155753

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00319297

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00633172

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_25

Significance: 0.00297967

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.00056139

Absent
MegP;A;En

Pattern: metacluster_1/pattern_10

Significance: 0.00297268

Absent
aB;CD180;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00037276400000000004

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000720837

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000985073

Absent
gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00717786

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.000633025

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0245803

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00917839

Absent
ILC1;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.000326571

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00576287

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00620637

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.00435057

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_20

Significance: 2.35917e-05

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0123191

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_19

Significance: 8.13084e-05

Absent
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 3.06175e-07

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.000136813

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.000721026

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00219423

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00268804

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00271263

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.000298815

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.000247435

Absent
T_LCMV;CD8+;D33;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.000457822

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00030267200000000003

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00159792

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000359565

Absent
Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.000393291

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.000692479

Absent
T_MLD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 6.0274e-05

Absent
Unique Cell types only Homer finds Runx3: #5

Cell typeModiscoHomer
prePLSM_B;A;GEOAbsent

Pattern: motif15.motif

Significance: 0.044464800000000006

B_SPLND;A;GEOAbsent

Pattern: motif12.motif

Significance: 0.0381948

apTreg;D;GEOAbsent

Pattern: motif12.motif

Significance: 0.0337742

MEL_Znc_di-cl;24h;D;EnAbsent

Pattern: motif9.motif

Significance: 0.00248041

Tfh_mut;A;CLAbsent

Pattern: motif16.motif

Significance: 0.0352885