In [1]:
# Parameters
data_name = "Runx1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:32:40,339 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Runx1: Motif: M09633_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Runx1: #61

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0022281

/

Pattern: metacluster_1/pattern_22

Significance: 0.052698

/

Pattern: metacluster_1/pattern_25

Significance: 0.022475099999999998

Pattern: motif3.motif

Significance: 0.015511600000000002

T_MLD;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 6.75707e-05

Pattern: motif4.motif

Significance: 0.000265625

T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 6.034349999999999e-06

/

Pattern: metacluster_1/pattern_15

Significance: 0.028516200000000002

Pattern: motif4.motif

Significance: 0.00022485400000000003

memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00011292399999999999

Pattern: motif4.motif

Significance: 0.0141674

memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 2.70669e-05

Pattern: motif4.motif

Significance: 0.0550721

memT_tmrD_lstr;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000227658

Pattern: motif4.motif

Significance: 0.0145618

memT_tmrD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 4.0927800000000005e-05

Pattern: motif4.motif

Significance: 0.0006786289999999999

iNKT;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00019637799999999998

Pattern: motif4.motif

Significance: 0.0223821

Spleen;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00105349

Pattern: motif16.motif

Significance: 0.0156099

3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_7

Significance: 6.88206e-06

Pattern: motif5.motif

Significance: 0.00566108

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.000416326

Pattern: motif5.motif

Significance: 0.0319856

aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00030475099999999997

Pattern: motif16.motif

Significance: 0.0355727

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0006114

Pattern: motif13.motif

Significance: 0.00215339

aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.00032878599999999997

Pattern: motif12.motif

Significance: 0.0400825

AML;D;En

Pattern: metacluster_1/pattern_8

Significance: 2.4055100000000003e-05

Pattern: motif5.motif

Significance: 0.042180800000000004

Mast;A;CL

Pattern: metacluster_0/pattern_5

Significance: 1.14882e-06

Pattern: motif7.motif

Significance: 0.0011779000000000002

BSPHL;A;CL

Pattern: metacluster_1/pattern_6

Significance: 2.49326e-06

Pattern: motif4.motif

Significance: 0.00543236

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.000333444

Pattern: motif11.motif

Significance: 0.049071699999999996

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 5.74948e-05

Pattern: motif8.motif

Significance: 0.0265871

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00045997800000000005

Pattern: motif7.motif

Significance: 0.0127912

MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.046781300000000005

/

Pattern: metacluster_1/pattern_25

Significance: 0.00398544

Pattern: motif9.motif

Significance: 0.00681234

3T3-L1;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00145511

Pattern: motif6.motif

Significance: 0.0123565

CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0016173

Pattern: motif11.motif

Significance: 0.0501111

CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.011014399999999999

Pattern: motif14.motif

Significance: 0.00254432

DC_BMD;A;CL

Pattern: metacluster_1/pattern_8

Significance: 4.3140200000000004e-05

Pattern: motif6.motif

Significance: 0.00814902

DP3a;A;CL

Pattern: metacluster_1/pattern_3

Significance: 4.66546e-05

Pattern: motif3.motif

Significance: 0.016923900000000002

ES;MEF;A;CL

Pattern: metacluster_1/pattern_9

Significance: 5.47021e-05

Pattern: motif6.motif

Significance: 0.00146533

pCMP;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.000135201

Pattern: motif4.motif

Significance: 0.011966899999999999

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_11

Significance: 3.6958899999999998e-06

Pattern: motif9.motif

Significance: 0.00911134

pGMP;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.0015448

/

Pattern: metacluster_1/pattern_17

Significance: 0.0124826

Pattern: motif5.motif

Significance: 0.011855500000000001

DC;A;En

Pattern: metacluster_1/pattern_8

Significance: 9.02912e-06

Pattern: motif7.motif

Significance: 0.032607699999999996

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00291677

Pattern: motif16.motif

Significance: 0.00115406

LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000341749

Pattern: motif12.motif

Significance: 0.0470027

3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_12

Significance: 0.000113365

Pattern: motif5.motif

Significance: 0.00710554

naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00158397

Pattern: motif12.motif

Significance: 0.043182

NK;IL2+IL12+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 2.38267e-06

Pattern: motif3.motif

Significance: 0.00045772900000000004

apCD4Eff;D;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00060075

Pattern: motif4.motif

Significance: 0.019209999999999998

NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_3

Significance: 2.04121e-05

Pattern: motif3.motif

Significance: 0.0195542

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 4.56187e-05

Pattern: motif4.motif

Significance: 0.00899539

NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.000202257

Pattern: motif5.motif

Significance: 0.030999799999999997

CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_13

Significance: 6.07332e-06

Pattern: motif18.motif

Significance: 0.00656242

wCH12;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00027770599999999996

/

Pattern: metacluster_1/pattern_21

Significance: 0.0586127

Pattern: motif15.motif

Significance: 0.0016017

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 8.306100000000001e-05

Pattern: motif5.motif

Significance: 0.00586246

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00287167

Pattern: motif11.motif

Significance: 0.016923900000000002

CLP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.000942215

Pattern: motif3.motif

Significance: 0.0322753

mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 8.81656e-06

Pattern: motif4.motif

Significance: 0.0189204

NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 8.68111e-08

Pattern: motif3.motif

Significance: 0.0571386

ILC1;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 7.091e-06

Pattern: motif4.motif

Significance: 0.0432091

ILC3;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 6.47809e-06

Pattern: motif3.motif

Significance: 0.039233

ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000224374

Pattern: motif4.motif

Significance: 0.010360799999999998

ILC3_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 1.9271400000000004e-06

Pattern: motif3.motif

Significance: 0.00885565

T_LCMV;CD8+;D8;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00030471700000000003

Pattern: motif4.motif

Significance: 0.000446559

T_LCMV;CD8+;D33;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 5.49193e-05

Pattern: motif4.motif

Significance: 0.0524038

T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 7.27892e-05

Pattern: motif4.motif

Significance: 0.059033100000000005

Muller;P12;D;En

Pattern: metacluster_1/pattern_10

Significance: 8.90425e-06

Pattern: motif5.motif

Significance: 0.011648100000000002

TExh_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.000127847

Pattern: motif4.motif

Significance: 0.0161665

TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_8

Significance: 6.02369e-05

Pattern: motif4.motif

Significance: 0.00111942

cntrl_memT;TCR_SV40-I_CD8+;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000293183

Pattern: motif4.motif

Significance: 0.023668099999999997

T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.000211688

Pattern: motif9.motif

Significance: 0.037241500000000004

T_MLD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 8.97998e-06

Pattern: motif4.motif

Significance: 0.0563812

T_MLD;TCR_SV40-I_CD8+;D21;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 9.03117e-05

Pattern: motif5.motif

Significance: 0.00020949

Unique Cell types only TF-MoDISco finds Runx1: #71

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.00022239799999999998

Absent
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00123496

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000449189

Absent
NK_SPLND;A;CL

Pattern: metacluster_0/pattern_5

Significance: 4.732340000000001e-06

Absent
proB;A;CL

Pattern: metacluster_1/pattern_7

Significance: 2.7216100000000002e-05

Absent
preB;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00355615

Absent
T_MLD;TCR_SV40-I_CD8+;D60;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 5.51413e-05

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0036626999999999996

Absent
MZ_B;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.014408

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.007559000000000001

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 9.911889999999999e-05

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00286155

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00825193

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00019790099999999997

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0010288

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00011601

Absent
DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00022187900000000002

/

Pattern: metacluster_1/pattern_21

Significance: 0.00523055

/

Pattern: metacluster_1/pattern_22

Significance: 4.21066e-05

Absent
MEL;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00349173

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00925274

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00545241

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.000365844

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_11

Significance: 5.6593100000000005e-05

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.000497499

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00099746

Absent
naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0134596

Absent
naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00427187

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00658817

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_13

Significance: 7.68843e-05

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_21

Significance: 0.00031083099999999997

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00132122

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00121217

Absent
CD4+CD8intTCR+CD69+CD24+;MHC2defM;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00530761

Absent
CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C

Pattern: metacluster_1/pattern_10

Significance: 0.00759957

Absent
CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00319809

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00129349

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00516445

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00101931

Absent
MCRPHG;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00539473

/

Pattern: metacluster_1/pattern_18

Significance: 0.00294625

Absent
DP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00020976

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00283144

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00227266

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00310276

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_25

Significance: 0.0143661

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.00021221

/

Pattern: metacluster_1/pattern_19

Significance: 0.013189700000000002

Absent
MegP;A;En

Pattern: metacluster_1/pattern_10

Significance: 0.0007039430000000001

Absent
aB;CD180;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00120259

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_23

Significance: 0.0078684

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000127633

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000265745

Absent
gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00273493

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_8

Significance: 9.941700000000001e-05

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00597807

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00352882

Absent
ILC1;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00012616100000000001

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00258988

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00258867

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.00232278

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.000390516

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00235186

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_19

Significance: 8.13084e-05

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00304172

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00011217700000000001

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0005213080000000001

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00256272

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.000699136

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 7.01533e-05

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_5

Significance: 5.05183e-05

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00043428900000000003

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000807668

Absent
Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00011724299999999999

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00020736

Absent
Unique Cell types only Homer finds Runx1: #3

Cell typeModiscoHomer
apTreg;D;GEOAbsent

Pattern: motif12.motif

Significance: 0.0337742

prePLSM_B;A;GEOAbsent

Pattern: motif15.motif

Significance: 0.0460127

416B;HMTP_SPNSN;CD34+;D;EnAbsent

Pattern: motif4.motif

Significance: 0.014234