In [1]:
# Parameters
data_name = "Pou2f1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:28:33,390 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Pou2f1: Motif: M00803_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Pou2f1: #18

Cell typeModiscoHomer
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0166707

/

Pattern: metacluster_0/pattern_14

Significance: 0.00187569

Pattern: motif3.motif

Significance: 0.0232483

BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0249787

Pattern: motif9.motif

Significance: 0.0376683

aB;CD180;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0132981

Pattern: motif14.motif

Significance: 0.013282200000000001

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0376802

Pattern: motif2.motif

Significance: 0.0471584

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.013285

Pattern: motif18.motif

Significance: 0.00903785

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.050105800000000006

Pattern: motif16.motif

Significance: 0.00300168

iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000588863

/

Pattern: metacluster_1/pattern_10

Significance: 0.00251806

Pattern: motif3.motif

Significance: 0.0183446

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0129257

/

Pattern: metacluster_1/pattern_19

Significance: 0.00470157

Pattern: motif13.motif

Significance: 0.037546800000000005

Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0304745

Pattern: motif4.motif

Significance: 0.052006399999999994

ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.030921499999999998

Pattern: motif5.motif

Significance: 0.045500900000000004

Melanotrope;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0597476

Pattern: motif17.motif

Significance: 0.049597300000000004

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0330994

/

Pattern: metacluster_0/pattern_7

Significance: 0.0557765

Pattern: motif2.motif

Significance: 0.029170299999999996

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0238252

Pattern: motif2.motif

Significance: 0.0503892

BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0519533

Pattern: motif13.motif

Significance: 0.045148400000000005

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0314099

Pattern: motif10.motif

Significance: 0.053222000000000005

Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0150944

Pattern: motif14.motif

Significance: 0.013379499999999999

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.0569999

/

Pattern: metacluster_0/pattern_21

Significance: 0.048981699999999996

Pattern: motif16.motif

Significance: 0.042901800000000004

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.038614300000000004

/

Pattern: metacluster_1/pattern_8

Significance: 0.00305021

Pattern: motif2.motif

Significance: 0.0228413

Unique Cell types only TF-MoDISco finds Pou2f1: #76

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.027610400000000004

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0515547

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.018950900000000003

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0107303

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0425793

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.04143019999999999

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00120844

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0079932

Absent
aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.047666900000000005

Absent
aB_LPS+IL21;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.05813530000000001

Absent
aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0597063

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.0430501

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0470133

Absent
MN1;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0503992

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0172666

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.021396000000000002

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.044604000000000005

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00773334

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0556174

Absent
Adipose;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.052409000000000004

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_22

Significance: 0.031815699999999995

Absent
PNCRS;A;CL

Pattern: metacluster_0/pattern_15

Significance: 0.0167077

Absent
eye-NRL_RTN;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.0404383

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.00838973

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00973375

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00272691

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00464783

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0127915

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.0275553

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.020621900000000002

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.0576222

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0537969

Absent
wCH12;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.036728699999999996

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.057188800000000005

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0189709

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0548043

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.051667

Absent
ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.011781299999999998

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.018618700000000002

Absent
TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0257928

Absent
Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.0487039

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.03364280000000001

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00833476

Absent
MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0270969

Absent
Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.012415899999999999

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00188744

/

Pattern: metacluster_0/pattern_16

Significance: 0.00517683

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.013260299999999997

/

Pattern: metacluster_0/pattern_17

Significance: 0.00212949

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.042055800000000004

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00307485

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_25

Significance: 0.0532875

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.012648600000000001

/

Pattern: metacluster_0/pattern_22

Significance: 0.0243239

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.0007915260000000001

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.040900599999999995

/

Pattern: metacluster_0/pattern_21

Significance: 0.043489

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0547481

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0577375

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00716607

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.00471581

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.00695436

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0482801

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.05702669999999999

/

Pattern: metacluster_1/pattern_18

Significance: 0.030195099999999996

Absent
ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0083614

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0286686

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0370237

Absent
ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00195396

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0574842

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0446397

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0594476

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.05318

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0214565

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.018814700000000004

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.039481999999999996

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.0126876

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00539162

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00172094

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0187925

/

Pattern: metacluster_0/pattern_11

Significance: 0.030966200000000003

Absent
wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0167706

/

Pattern: metacluster_0/pattern_8

Significance: 0.0009745089999999999

Absent
Unique Cell types only Homer finds Pou2f1: #4

Cell typeModiscoHomer
LVR;8wks;D;EnAbsent

Pattern: motif7.motif

Significance: 0.037868900000000004

CN_PHT_RCPTR;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.049812

wCH12_drug;A;CLAbsent

Pattern: motif10.motif

Significance: 0.0475029

CH12.LX;D;EnAbsent

Pattern: motif5.motif

Significance: 0.010304