In [1]:
# Parameters
data_name = "Cbfb"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 10:59:15,016 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Cbfb: Motif: M09448_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Cbfb: #59

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.000223248

/

Pattern: metacluster_1/pattern_22

Significance: 0.052698

Pattern: motif3.motif

Significance: 0.015511600000000002

T_MLD;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.000172499

Pattern: motif4.motif

Significance: 0.0027403

T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.000488407

Pattern: motif4.motif

Significance: 0.000377614

memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00116972

Pattern: motif4.motif

Significance: 0.0225209

memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0005057109999999999

Pattern: motif4.motif

Significance: 0.0076295

memT_tmrD_lstr;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00321888

Pattern: motif4.motif

Significance: 0.0136685

memT_tmrD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000999281

Pattern: motif4.motif

Significance: 0.00298351

iNKT;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00312631

Pattern: motif4.motif

Significance: 0.0032151

Spleen;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00533806

Pattern: motif16.motif

Significance: 0.0320247

3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.000377885

Pattern: motif5.motif

Significance: 0.0426676

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00243192

Pattern: motif5.motif

Significance: 0.0035423000000000004

aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00380536

Pattern: motif16.motif

Significance: 0.0355727

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.000980373

Pattern: motif13.motif

Significance: 0.00329539

AML;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.000402509

Pattern: motif5.motif

Significance: 0.042180800000000004

Mast;A;CL

Pattern: metacluster_0/pattern_5

Significance: 0.000873832

Pattern: motif7.motif

Significance: 0.00132632

BSPHL;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00010366

Pattern: motif4.motif

Significance: 0.00543236

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0008593219999999999

Pattern: motif11.motif

Significance: 0.050243699999999995

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00159263

Pattern: motif8.motif

Significance: 0.00381851

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 2.4915700000000003e-05

Pattern: motif7.motif

Significance: 0.00876228

MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_25

Significance: 0.00398544

Pattern: motif9.motif

Significance: 0.00659363

3T3-L1;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0006884360000000001

Pattern: motif6.motif

Significance: 0.00463933

CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00704428

Pattern: motif11.motif

Significance: 0.0501111

CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.011014399999999999

Pattern: motif14.motif

Significance: 0.0334999

DC_BMD;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00110742

Pattern: motif6.motif

Significance: 4.20727e-06

DP3a;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00261968

Pattern: motif3.motif

Significance: 0.0225879

ES;MEF;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00231677

Pattern: motif6.motif

Significance: 0.026710400000000006

pCMP;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00322485

Pattern: motif4.motif

Significance: 0.011966899999999999

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_11

Significance: 0.000603448

Pattern: motif9.motif

Significance: 0.00677901

pGMP;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.00032534400000000003

/

Pattern: metacluster_1/pattern_17

Significance: 0.021694400000000003

Pattern: motif5.motif

Significance: 0.011855500000000001

DC;A;En

Pattern: metacluster_1/pattern_8

Significance: 0.000254152

Pattern: motif7.motif

Significance: 0.00194861

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.000993315

Pattern: motif16.motif

Significance: 0.00695739

LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00314946

Pattern: motif12.motif

Significance: 0.0416346

3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_12

Significance: 0.00218326

Pattern: motif5.motif

Significance: 0.000530345

NK;IL2+IL12+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.000298999

Pattern: motif3.motif

Significance: 0.000348403

apCD4Eff;D;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00378395

Pattern: motif4.motif

Significance: 0.00510904

NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00063825

Pattern: motif3.motif

Significance: 0.0195542

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000511142

Pattern: motif4.motif

Significance: 0.00694387

NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.000537048

Pattern: motif5.motif

Significance: 0.00919906

CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00186879

Pattern: motif18.motif

Significance: 0.0040654

wCH12;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00206989

Pattern: motif15.motif

Significance: 0.027987900000000003

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00221236

Pattern: motif5.motif

Significance: 0.000542354

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.000864984

Pattern: motif11.motif

Significance: 0.00513179

CLP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 8.04385e-05

Pattern: motif3.motif

Significance: 0.00431526

mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.000592764

Pattern: motif4.motif

Significance: 0.00496933

NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.000109188

Pattern: motif3.motif

Significance: 0.0571386

ILC1;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0006779210000000001

Pattern: motif4.motif

Significance: 0.00382911

ILC3;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.000444239

Pattern: motif3.motif

Significance: 0.00861528

ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00254483

Pattern: motif4.motif

Significance: 0.010360799999999998

ILC3_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 9.3787e-05

Pattern: motif3.motif

Significance: 0.00023119700000000002

T_LCMV;CD8+;D8;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00250962

Pattern: motif4.motif

Significance: 0.00440495

T_LCMV;CD8+;D33;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00151143

Pattern: motif4.motif

Significance: 0.0524038

T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00148777

Pattern: motif4.motif

Significance: 0.059033100000000005

Muller;P12;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.000489097

Pattern: motif5.motif

Significance: 0.000231996

TExh_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00299051

Pattern: motif4.motif

Significance: 0.0161665

TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00108023

Pattern: motif4.motif

Significance: 0.0188078

cntrl_memT;TCR_SV40-I_CD8+;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00383171

Pattern: motif4.motif

Significance: 0.0244524

T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00321753

Pattern: motif9.motif

Significance: 0.031104400000000004

T_MLD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00035949

Pattern: motif4.motif

Significance: 0.0563812

T_MLD;TCR_SV40-I_CD8+;D21;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00114991

Pattern: motif5.motif

Significance: 0.00524929

Unique Cell types only TF-MoDISco finds Cbfb: #73

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.00206419

Absent
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00435503

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00385549

Absent
NK_SPLND;A;CL

Pattern: metacluster_0/pattern_5

Significance: 0.00046015199999999997

Absent
proB;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0009160069999999999

Absent
preB;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00152721

Absent
T_MLD;TCR_SV40-I_CD8+;D60;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.00187057

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.00282441

Absent
MZ_B;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0256615

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00744434

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0012582000000000001

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00286155

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00355805

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00308825

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00275473

Absent
aB_LSP+a_d_dextran;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.0029276999999999997

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00237416

Absent
DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00129884

/

Pattern: metacluster_1/pattern_21

Significance: 0.00228244

/

Pattern: metacluster_1/pattern_22

Significance: 4.21066e-05

Absent
MEL;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00792383

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0102417

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00353378

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00402269

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00166074

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00229521

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.00551678

Absent
naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0101825

Absent
naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0209439

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.010580899999999999

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00186675

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_21

Significance: 0.00451561

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00602314

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00535626

Absent
CD4+CD8intTCR+CD69+CD24+;MHC2defM;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00689455

Absent
CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C

Pattern: metacluster_1/pattern_10

Significance: 0.00759957

Absent
CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.000927263

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00162248

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00999682

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0064602

Absent
MCRPHG;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00144051

/

Pattern: metacluster_1/pattern_18

Significance: 0.00456477

Absent
DP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0033082000000000003

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.002522

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00587592

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.000375551

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_25

Significance: 0.0143661

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_13

Significance: 0.00371799

/

Pattern: metacluster_1/pattern_19

Significance: 0.0168053

Absent
MegP;A;En

Pattern: metacluster_1/pattern_10

Significance: 0.00353075

Absent
aB;CD180;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.00038144300000000003

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_23

Significance: 0.0078684

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00252452

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0030515

Absent
gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00900193

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00237301

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00452008

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00155154

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.000828072

Absent
ILC1;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00124566

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00016419700000000001

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00685294

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.00472558

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.000634838

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0006484630000000001

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.0008507660000000001

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.000456154

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00181952

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00416671

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.0008026410000000001

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00400026

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00284344

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.000505796

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00385962

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000520753

Absent
Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0038272

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00212333

Absent
Unique Cell types only Homer finds Cbfb: #3

Cell typeModiscoHomer
apTreg;D;GEOAbsent

Pattern: motif12.motif

Significance: 0.0451068

prePLSM_B;A;GEOAbsent

Pattern: motif15.motif

Significance: 0.044464800000000006

416B;HMTP_SPNSN;CD34+;D;EnAbsent

Pattern: motif4.motif

Significance: 0.011065