In [1]:
# Parameters
data_name = "Zscan10"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:54:29,155 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Zscan10: Motif: M00767_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Zscan10: #5

Cell typeModiscoHomer
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0364346

/

Pattern: metacluster_1/pattern_10

Significance: 0.0534778

Pattern: motif20.motif

Significance: 0.0526249

restingB;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0087715

Pattern: motif12.motif

Significance: 0.019677700000000003

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.014393000000000001

Pattern: motif2.motif

Significance: 0.0427776

gamma_delta_TCR_MCR;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0148665

Pattern: motif2.motif

Significance: 0.0567446

CH12.LX;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.027514599999999997

Pattern: motif4.motif

Significance: 0.033253899999999996

Unique Cell types only TF-MoDISco finds Zscan10: #89

Cell typeModiscoHomer
naiveCD8;A;CL

Pattern: metacluster_0/pattern_0

Significance: 0.030114799999999997

Absent
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0357574

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.028747

Absent
NK_SPLND;A;CL

Pattern: metacluster_0/pattern_0

Significance: 0.039636300000000006

Absent
proB;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0194126

Absent
preB;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0104969

/

Pattern: metacluster_1/pattern_21

Significance: 0.00461423

Absent
immatureB;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.00820657

Absent
matureB;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0079541

Absent
MZ_B;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.011446

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0102596

Absent
GC_B;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00714633

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.05526709999999999

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00879301

Absent
aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.036408800000000005

Absent
aB_LPS+IL21;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0145671

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.051449

Absent
aB_CD40+IL4;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.013276900000000001

Absent
A20;B-lymphoma;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00630495

Absent
AML;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00722457

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.05184400000000001

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.046228899999999996

Absent
naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.044827

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0409028

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.050425199999999996

Absent
CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0449268

Absent
CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.037148400000000005

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0425857

Absent
MCRPHG;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00861557

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.03171090000000001

/

Pattern: metacluster_1/pattern_5

Significance: 0.0539682

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.049980300000000005

Absent
Heart;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.0541428

Absent
Adipose;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.026025599999999996

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0506515

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_0

Significance: 0.0310666

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0371856

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0387056

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0213992

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00674395

Absent
wCH12;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.05219209999999999

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0180162

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00805431

Absent
mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.041053

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0194888

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0537047

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0316886

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.037228500000000005

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.03490019999999999

Absent
ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.055568200000000005

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0416394

Absent
T_LCMV;CD8+;D33;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0458384

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.055913199999999996

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0377616

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0293402

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.015447799999999998

Absent
B_SPLND;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.014827799999999999

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00755072

Absent
MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0290575

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.05205219999999999

Absent
DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0266454

Absent
DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0117456

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.05536749999999999

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.059142099999999996

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.05837230000000001

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.0545797

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.045787699999999994

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.052798000000000005

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0450212

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0585534

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.046079

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_4

Significance: 0.00637353

Absent
MegP;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.010341

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00890798

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.0375514

Absent
pGMP;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.00735863

Absent
DC;A;En

Pattern: metacluster_1/pattern_4

Significance: 0.0212953

Absent
T_SPLND_blstCLTRD;CD4+;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.038458

Absent
immatureB_SPLND;CD43-_CD11b-;D;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00893613

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.05785030000000001

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0484376

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.0548703

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0487149

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0542715

Absent
LNG;P0;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0374815

/

Pattern: metacluster_1/pattern_2

Significance: 0.027042200000000002

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0533239

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.05183340000000001

Absent
immatureB_SPLND;CD43-_CD11b-;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00838074

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_9

Significance: 0.0564367

Absent
Muller;P12;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.05816

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.0532288

Absent
Unique Cell types only Homer finds Zscan10: #5

Cell typeModiscoHomer
iNKT;A;GEOAbsent

Pattern: motif2.motif

Significance: 0.0357056

CD4+CD8-TCR+CD25+Foxp3+;A;CLAbsent

Pattern: motif14.motif

Significance: 0.027249400000000003

DP;A;CLAbsent

Pattern: motif18.motif

Significance: 0.051097199999999995

T_LCMV;CD8+;D35;A;GEOAbsent

Pattern: motif2.motif

Significance: 0.05755830000000001

T_MLD;TCR_SV40-I_CD8+;D14;A;GEOAbsent

Pattern: motif2.motif

Significance: 0.0365806