In [1]:
# Parameters
data_name = "Ptf1a"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:30:12,681 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Ptf1a: Motif: M08757_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Ptf1a: #29

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.048494699999999995

/

Pattern: metacluster_1/pattern_2

Significance: 0.025767

Pattern: motif5.motif

Significance: 0.00117284

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.00770948

Pattern: motif12.motif

Significance: 0.0385999

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0410005

Pattern: motif5.motif

Significance: 0.00354446

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.000800444

Pattern: motif15.motif

Significance: 0.0112068

preB;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0569808

/

Pattern: metacluster_1/pattern_4

Significance: 0.00151095

Pattern: motif12.motif

Significance: 0.0108794

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.000597091

Pattern: motif15.motif

Significance: 0.0241832

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.03340119999999999

Pattern: motif10.motif

Significance: 0.00721624

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00784307

/

Pattern: metacluster_1/pattern_21

Significance: 0.010606200000000001

Pattern: motif22.motif

Significance: 0.023848599999999998

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.000968733

Pattern: motif9.motif

Significance: 0.031143999999999998

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000128452

Pattern: motif9.motif

Significance: 0.0185393

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.000597456

/

Pattern: metacluster_1/pattern_18

Significance: 0.00363543

Pattern: motif11.motif

Significance: 0.014925399999999998

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.033243

/

Pattern: metacluster_1/pattern_5

Significance: 0.024084400000000002

Pattern: motif10.motif

Significance: 0.0158857

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00645957

Pattern: motif9.motif

Significance: 0.000668263

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00881364

Pattern: motif13.motif

Significance: 0.00599209

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0378542

/

Pattern: metacluster_1/pattern_7

Significance: 0.00265161

Pattern: motif11.motif

Significance: 0.023811000000000002

ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00261536

/

Pattern: metacluster_1/pattern_5

Significance: 0.0561014

Pattern: motif14.motif

Significance: 0.041265699999999995

Muscle;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0364856

/

Pattern: metacluster_1/pattern_16

Significance: 0.0246981

Pattern: motif19.motif

Significance: 0.056336000000000004

Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00875635

Pattern: motif13.motif

Significance: 0.0144249

BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.038988300000000004

Pattern: motif15.motif

Significance: 0.0147827

BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0229963

Pattern: motif7.motif

Significance: 0.05719640000000001

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0433583

/

Pattern: metacluster_1/pattern_10

Significance: 0.00242779

Pattern: motif2.motif

Significance: 0.0507829

KDNY;P0;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.0496405

/

Pattern: metacluster_1/pattern_9

Significance: 0.0287128

Pattern: motif15.motif

Significance: 0.00197615

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00368821

Pattern: motif18.motif

Significance: 0.00712961

wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00143385

Pattern: motif13.motif

Significance: 0.00840535

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.00872596

Pattern: motif2.motif

Significance: 0.0096045

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00971516

Pattern: motif16.motif

Significance: 0.013178

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00669558

Pattern: motif4.motif

Significance: 0.00242625

Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.011445100000000001

Pattern: motif8.motif

Significance: 0.0507807

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00705819

Pattern: motif19.motif

Significance: 0.05435449999999999

Unique Cell types only TF-MoDISco finds Ptf1a: #76

Cell typeModiscoHomer
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0339208

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.0488144

Absent
GC_B;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0499205

Absent
B_SPLND;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0252987

Absent
aB_LPS+IL21;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0388841

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0541841

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.048633499999999996

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_1

Significance: 0.0572689

Absent
MN1;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0254905

Absent
Tfh_LCMV;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0458839

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0329419

/

Pattern: metacluster_1/pattern_13

Significance: 0.0307514

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00642116

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.014252200000000001

/

Pattern: metacluster_1/pattern_13

Significance: 0.057475

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.000190602

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.0318998

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.037839300000000006

/

Pattern: metacluster_0/pattern_15

Significance: 0.000111052

/

Pattern: metacluster_0/pattern_22

Significance: 0.0479913

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0235995

/

Pattern: metacluster_1/pattern_5

Significance: 0.0192541

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.053144000000000004

/

Pattern: metacluster_1/pattern_4

Significance: 0.0516981

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0020442999999999998

/

Pattern: metacluster_0/pattern_22

Significance: 0.0369166

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0245589

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0452741

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000873585

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.000135227

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.000137197

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0323482

/

Pattern: metacluster_0/pattern_8

Significance: 0.001811

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00039116199999999997

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.025894900000000002

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0314175

Absent
DP;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.046632099999999996

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0562696

/

Pattern: metacluster_1/pattern_9

Significance: 0.0488211

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.05613390000000001

/

Pattern: metacluster_1/pattern_3

Significance: 0.034707800000000004

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0463949

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.025059400000000003

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0255761

/

Pattern: metacluster_1/pattern_4

Significance: 0.052204499999999994

/

Pattern: metacluster_1/pattern_5

Significance: 0.00795169

Absent
wES;GRM;E16.5;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0465073

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0558096

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.000550086

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00710638

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00623224

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_4

Significance: 0.0570107

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.027826

/

Pattern: metacluster_1/pattern_12

Significance: 0.0208459

Absent
STMCH;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.029395799999999996

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_1

Significance: 0.010819

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_0

Significance: 0.0373685

/

Pattern: metacluster_0/pattern_13

Significance: 0.00491498

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.05747000000000001

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.014912200000000002

Absent
ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.016138999999999997

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_0

Significance: 0.0401527

Absent
ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.041891399999999995

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0432025

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0521226

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.0184877

/

Pattern: metacluster_0/pattern_9

Significance: 0.0339549

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0404066

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0388234

Absent
CH12_QNTPLE;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.048119999999999996

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.0410677

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0050721

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0122586

/

Pattern: metacluster_1/pattern_6

Significance: 0.0410952

Absent
mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.057888199999999994

Absent
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.028977099999999995

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.05796080000000001

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.00515553

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0142942

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.048733099999999994

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.059010900000000005

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.040807800000000005

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00790316

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0278528

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.05461900000000001

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00254969

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.058307000000000005

/

Pattern: metacluster_0/pattern_4

Significance: 0.000380419

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.00666601

/

Pattern: metacluster_0/pattern_12

Significance: 0.0495195

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00846623

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0415896

/

Pattern: metacluster_1/pattern_5

Significance: 0.059278599999999994

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.048512900000000005

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0274719

Absent
Unique Cell types only Homer finds Ptf1a: #6

Cell typeModiscoHomer
MPP;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0474532

pCMP;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0535368

wES;FaceP;E11.5;D;EnAbsent

Pattern: motif7.motif

Significance: 0.048834699999999995

MCRPHG_BMD.UnStmltd;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.059477800000000004

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0297645

MCRPHG_BMD.LPD_Stmltd;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.0476811