In [1]:
# Parameters
data_name = "Cebpa"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 10:59:57,931 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Cebpa: Motif: M00993_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Cebpa: #47

Cell typeModiscoHomer
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.019196900000000003

Pattern: motif5.motif

Significance: 0.054361599999999996

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00250825

/

Pattern: metacluster_1/pattern_16

Significance: 0.050169099999999994

Pattern: motif6.motif

Significance: 0.00897417

AML;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.00748012

/

Pattern: metacluster_1/pattern_11

Significance: 0.0312978

Pattern: motif3.motif

Significance: 4.69926e-05

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0170257

/

Pattern: metacluster_1/pattern_7

Significance: 0.00033020300000000005

Pattern: motif11.motif

Significance: 0.00134867

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00510684

/

Pattern: metacluster_1/pattern_7

Significance: 0.0277363

Pattern: motif6.motif

Significance: 0.025422900000000002

/

Pattern: motif10.motif

Significance: 0.0334347

DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.011922

/

Pattern: metacluster_1/pattern_7

Significance: 0.035068699999999994

Pattern: motif5.motif

Significance: 0.00580333

/

Pattern: motif11.motif

Significance: 0.0462421

BSPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00355993

/

Pattern: metacluster_1/pattern_7

Significance: 0.045630699999999996

Pattern: motif6.motif

Significance: 7.47234e-05

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.00652918

Pattern: motif9.motif

Significance: 0.058101599999999996

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0123686

/

Pattern: metacluster_1/pattern_6

Significance: 0.0144362

Pattern: motif6.motif

Significance: 0.00980228

NTRPHL;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00673096

Pattern: motif3.motif

Significance: 0.034477499999999994

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0124337

/

Pattern: metacluster_1/pattern_6

Significance: 0.0350569

Pattern: motif2.motif

Significance: 0.034431199999999995

NIH3T3;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0046374

/

Pattern: metacluster_1/pattern_6

Significance: 0.025269999999999997

Pattern: motif5.motif

Significance: 0.0008929680000000001

MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0341219

/

Pattern: metacluster_0/pattern_16

Significance: 0.041152600000000004

/

Pattern: metacluster_0/pattern_17

Significance: 0.012512299999999999

Pattern: motif7.motif

Significance: 0.05405359999999999

3T3-L1;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.040311599999999996

/

Pattern: metacluster_1/pattern_9

Significance: 0.0345346

Pattern: motif9.motif

Significance: 0.038608300000000005

DC_BMD;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.000116493

/

Pattern: metacluster_1/pattern_9

Significance: 0.00745334

Pattern: motif11.motif

Significance: 0.00133845

MCRPHG;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00763158

/

Pattern: metacluster_1/pattern_7

Significance: 0.0586466

Pattern: motif7.motif

Significance: 0.000109517

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00984514

Pattern: motif13.motif

Significance: 0.00641598

Adrenal;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00974841

Pattern: motif7.motif

Significance: 0.0007316060000000001

Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0035400999999999996

/

Pattern: metacluster_0/pattern_8

Significance: 0.0276353

Pattern: motif13.motif

Significance: 0.00106832

placenta;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00706075

Pattern: motif9.motif

Significance: 0.0183096

pMeg;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00378643

Pattern: motif3.motif

Significance: 7.340560000000001e-05

MegP;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.009190299999999998

Pattern: motif4.motif

Significance: 7.62078e-05

pCMP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00227658

Pattern: motif9.motif

Significance: 0.0149422

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00106538

/

Pattern: metacluster_1/pattern_8

Significance: 0.0244489

Pattern: motif6.motif

Significance: 0.025491800000000002

pGMP;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00270683

Pattern: motif3.motif

Significance: 3.0176399999999998e-05

DC;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00785687

/

Pattern: metacluster_1/pattern_7

Significance: 0.028348500000000002

Pattern: motif5.motif

Significance: 0.0008223869999999999

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00179007

Pattern: motif5.motif

Significance: 0.00331158

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00609735

Pattern: motif3.motif

Significance: 2.65397e-05

LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.00713295

/

Pattern: metacluster_0/pattern_6

Significance: 0.049313800000000005

Pattern: motif3.motif

Significance: 0.00119163

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00176554

Pattern: motif6.motif

Significance: 0.00111662

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0591312

/

Pattern: metacluster_1/pattern_12

Significance: 0.027563999999999998

Pattern: motif15.motif

Significance: 0.0507279

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00433116

/

Pattern: metacluster_1/pattern_7

Significance: 0.039013099999999995

Pattern: motif4.motif

Significance: 0.000630065

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00770392

/

Pattern: metacluster_1/pattern_10

Significance: 0.0296134

Pattern: motif6.motif

Significance: 0.000155186

/

Pattern: motif11.motif

Significance: 0.028453199999999998

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.05777569999999999

/

Pattern: metacluster_1/pattern_9

Significance: 0.011945200000000001

Pattern: motif17.motif

Significance: 0.036015899999999997

LVR;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00710606

/

Pattern: metacluster_0/pattern_11

Significance: 0.0581509

Pattern: motif3.motif

Significance: 6.161300000000001e-05

NTRPHL;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.013741499999999999

/

Pattern: metacluster_0/pattern_7

Significance: 0.042728699999999994

/

Pattern: metacluster_0/pattern_12

Significance: 0.000940267

Pattern: motif5.motif

Significance: 0.000645205

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_9

Significance: 0.000912767

Pattern: motif15.motif

Significance: 0.0170824

LVR;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00341225

Pattern: motif9.motif

Significance: 0.0008594210000000001

LNG;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00876119

/

Pattern: metacluster_0/pattern_6

Significance: 0.0211048

Pattern: motif2.motif

Significance: 4.07063e-05

LNG;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00480571

/

Pattern: metacluster_1/pattern_5

Significance: 0.0310841

Pattern: motif4.motif

Significance: 0.00101267

Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00303424

/

Pattern: metacluster_1/pattern_13

Significance: 0.0580756

Pattern: motif10.motif

Significance: 0.0174732

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00742016

Pattern: motif2.motif

Significance: 0.00010017

Adipose;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.038245999999999995

/

Pattern: metacluster_0/pattern_1

Significance: 0.032757

Pattern: motif1.motif

Significance: 0.00015754

CRBLM;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0316116

Pattern: motif10.motif

Significance: 0.0474587

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0009743289999999999

Pattern: motif6.motif

Significance: 0.000100146

Muller;P12;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0111141

/

Pattern: metacluster_1/pattern_11

Significance: 0.041576199999999994

Pattern: motif9.motif

Significance: 0.00568384

/

Pattern: motif15.motif

Significance: 0.00304597

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.056770600000000004

/

Pattern: metacluster_1/pattern_10

Significance: 0.027270099999999995

Pattern: motif8.motif

Significance: 0.0231584

Unique Cell types only TF-MoDISco finds Cebpa: #86

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00238937

Absent
naiveCD8;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0245439

Absent
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.052060699999999994

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0231115

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0415596

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00401849

Absent
Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0599321

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.05551180000000001

Absent
CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0583685

Absent
CD4+CD8-TCR+CD25+Foxp3-;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0534889

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.029524

/

Pattern: metacluster_1/pattern_11

Significance: 0.00943592

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.049823599999999996

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.034504599999999996

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00571158

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.022021900000000004

Absent
Heart;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0008037760000000001

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0118238

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.028648200000000002

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_9

Significance: 0.0391532

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.04416919999999999

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.050850099999999995

/

Pattern: metacluster_1/pattern_21

Significance: 0.059602999999999996

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.014906

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0138238

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0338079

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0303507

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0448231

Absent
ILC1;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0319702

Absent
NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.030490499999999997

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0515649

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0363432

Absent
mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.05449249999999999

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0565636

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0182549

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0558491

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0245378

Absent
ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0551025

Absent
ILC3_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.054237400000000005

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0491212

Absent
T_MLD;TCR_SV40-I_CD8+;D60;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.031227299999999996

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.045598900000000005

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0404311

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.055218399999999994

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.019496299999999998

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.037752

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0508741

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.05534069999999999

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0592981

/

Pattern: metacluster_0/pattern_11

Significance: 0.00113711

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.000506975

/

Pattern: metacluster_0/pattern_15

Significance: 0.058325800000000004

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0200274

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0588428

Absent
NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.050319

Absent
NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0456745

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.030515499999999997

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.018007099999999998

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.030496199999999998

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00189842

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.0477023

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0407543

Absent
3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_14

Significance: 0.00942167

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0325551

Absent
ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.04743030000000001

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00113624

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0542518

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00018214599999999997

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.00106532

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00717207

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0413517

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.043593400000000004

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_13

Significance: 0.0218209

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0506391

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.011058700000000001

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_15

Significance: 0.025248

Absent
wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_14

Significance: 0.049729

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.024945

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.025554300000000002

Absent
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0180324

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_9

Significance: 0.00897274

Absent
wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.05777519999999999

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.025208

Absent
LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00742709

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00136719

Absent
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_9

Significance: 0.056501499999999996

/

Pattern: metacluster_0/pattern_10

Significance: 0.05263430000000001

/

Pattern: metacluster_0/pattern_12

Significance: 0.00825002

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0240266

Absent
MEL;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0153009

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.000501361

Absent
MN1;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.04183030000000001

Absent
Unique Cell types only Homer finds Cebpa: #2

Cell typeModiscoHomer
restingB;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0587057

aB_LPS+IL21;A;CLAbsent

Pattern: motif15.motif

Significance: 0.05838009999999999