In [1]:
# Parameters
data_name = "Cebpg"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:00:11,295 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Cebpg: Motif: M08840_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Cebpg: #45

Cell typeModiscoHomer
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00747995

Pattern: motif5.motif

Significance: 0.0336503

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00246917

Pattern: motif6.motif

Significance: 0.0048878

AML;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0095262

/

Pattern: metacluster_1/pattern_11

Significance: 0.0512595

Pattern: motif3.motif

Significance: 0.00812466

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0148351

Pattern: motif11.motif

Significance: 0.0184035

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00451324

Pattern: motif10.motif

Significance: 0.010151299999999999

DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00620445

Pattern: motif5.motif

Significance: 0.0205457

/

Pattern: motif11.motif

Significance: 0.0314157

BSPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00329677

Pattern: motif6.motif

Significance: 0.00019292900000000002

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.00797096

Pattern: motif9.motif

Significance: 0.00208241

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.01243

Pattern: motif6.motif

Significance: 0.017885400000000003

NTRPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0355206

/

Pattern: metacluster_1/pattern_4

Significance: 0.0047512

Pattern: motif3.motif

Significance: 0.0339541

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.011289200000000001

Pattern: motif2.motif

Significance: 0.0187065

NIH3T3;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00326175

Pattern: motif5.motif

Significance: 0.0598403

3T3-L1;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.0561846

/

Pattern: metacluster_1/pattern_9

Significance: 0.011381

Pattern: motif9.motif

Significance: 0.020192500000000002

DC_BMD;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0474056

/

Pattern: metacluster_1/pattern_9

Significance: 0.05711569999999999

Pattern: motif11.motif

Significance: 0.00257087

MCRPHG;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0170536

Pattern: motif7.motif

Significance: 0.0199293

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0529481

Pattern: motif13.motif

Significance: 0.045108999999999996

Adrenal;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00745781

Pattern: motif7.motif

Significance: 0.05700830000000001

Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00333855

Pattern: motif13.motif

Significance: 0.00178108

placenta;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0104241

Pattern: motif9.motif

Significance: 0.00987777

pMeg;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.0045601999999999995

Pattern: motif3.motif

Significance: 0.00440051

MegP;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.00618001

Pattern: motif4.motif

Significance: 0.00129252

pCMP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0203526

Pattern: motif9.motif

Significance: 0.00888967

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00212292

Pattern: motif6.motif

Significance: 0.0408323

pGMP;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00388044

Pattern: motif3.motif

Significance: 0.013391499999999999

DC;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00506571

Pattern: motif5.motif

Significance: 0.047443400000000004

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.007327199999999999

Pattern: motif5.motif

Significance: 0.0009311710000000001

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00546605

Pattern: motif3.motif

Significance: 0.0170222

LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.00511745

Pattern: motif3.motif

Significance: 0.00103542

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00354701

Pattern: motif6.motif

Significance: 0.00115319

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00433116

/

Pattern: metacluster_1/pattern_7

Significance: 0.0492696

Pattern: motif4.motif

Significance: 0.055908400000000004

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00588184

/

Pattern: metacluster_1/pattern_10

Significance: 0.0572668

Pattern: motif6.motif

Significance: 0.0335107

/

Pattern: motif11.motif

Significance: 0.031512599999999995

/

Pattern: motif14.motif

Significance: 0.052006399999999994

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00278397

Pattern: motif17.motif

Significance: 1.39606e-06

LVR;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.004285199999999999

Pattern: motif3.motif

Significance: 0.0289308

NTRPHL;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.014772799999999997

/

Pattern: metacluster_0/pattern_12

Significance: 0.00155783

Pattern: motif5.motif

Significance: 0.00184941

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_9

Significance: 0.00511826

Pattern: motif15.motif

Significance: 0.0046799

LVR;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00962292

Pattern: motif9.motif

Significance: 0.00324762

LNG;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00512746

/

Pattern: metacluster_0/pattern_6

Significance: 0.0456069

Pattern: motif2.motif

Significance: 0.00764528

LNG;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00372541

/

Pattern: metacluster_1/pattern_5

Significance: 0.056845400000000004

Pattern: motif4.motif

Significance: 0.0544285

Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00211786

/

Pattern: metacluster_1/pattern_13

Significance: 0.0521904

Pattern: motif10.motif

Significance: 0.00509131

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00690075

Pattern: motif2.motif

Significance: 0.00084583

Adipose;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.0374129

/

Pattern: metacluster_0/pattern_1

Significance: 0.0221391

Pattern: motif1.motif

Significance: 0.00691067

CRBLM;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.027162000000000002

Pattern: motif10.motif

Significance: 0.0531846

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00595661

Pattern: motif6.motif

Significance: 0.00999437

Muller;P12;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.00374945

Pattern: motif9.motif

Significance: 0.041995099999999994

/

Pattern: motif15.motif

Significance: 0.00160796

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0435431

/

Pattern: metacluster_1/pattern_10

Significance: 0.0443

Pattern: motif8.motif

Significance: 0.0321861

Unique Cell types only TF-MoDISco finds Cebpg: #53

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00612123

Absent
naiveCD8;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0581974

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_9

Significance: 0.055344700000000004

Absent
wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.05777519999999999

Absent
LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0405837

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.050194

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.059635400000000005

Absent
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.059099

/

Pattern: metacluster_0/pattern_12

Significance: 0.00321586

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.055195400000000006

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.059478699999999995

Absent
MEL;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.00964828

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.0122949

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0350175

/

Pattern: metacluster_0/pattern_17

Significance: 0.042013800000000004

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00334253

Absent
MN1;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.05255309999999999

/

Pattern: metacluster_1/pattern_15

Significance: 0.0591191

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0271413

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.05250740000000001

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.0224515

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0326876

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0440773

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0433556

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.054127800000000004

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00190251

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.030776400000000002

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0468561

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00485608

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.04643869999999999

Absent
Heart;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.019538

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0248578

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.00836772

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.0510587

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.041425

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_9

Significance: 0.0507271

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.037266900000000006

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.059602999999999996

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0381561

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.029692200000000002

Absent
3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_14

Significance: 0.0101934

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0501904

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0541345

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.0557759

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0591312

/

Pattern: metacluster_1/pattern_12

Significance: 0.0508513

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_20

Significance: 1.79815e-07

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.030308699999999997

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0329246

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0284022

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.030303700000000003

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.05949490000000001

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0435113

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0358279

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.044789300000000004

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.051963499999999996

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0490285

Absent
Unique Cell types only Homer finds Cebpg: #3

Cell typeModiscoHomer
restingB;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0587057

ILC1_AbxGRMFree;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.0205273

aB_LPS+IL21;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0564212