In [1]:
# Parameters
data_name = "Cebpd"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:00:06,762 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Cebpd: Motif: M00989_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Cebpd: #46

Cell typeModiscoHomer
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.011748

Pattern: motif5.motif

Significance: 0.049378399999999996

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00230506

Pattern: motif6.motif

Significance: 0.00466922

AML;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0101612

Pattern: motif3.motif

Significance: 0.00016253899999999998

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0006355569999999999

Pattern: motif11.motif

Significance: 0.000455501

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00557071

Pattern: motif10.motif

Significance: 0.013062700000000002

DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.011281900000000001

Pattern: motif5.motif

Significance: 0.00336678

/

Pattern: motif11.motif

Significance: 0.024689700000000002

BSPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00559801

Pattern: motif6.motif

Significance: 0.000241385

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.00973745

Pattern: motif9.motif

Significance: 0.016221799999999998

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.014012299999999998

Pattern: motif6.motif

Significance: 0.00269058

NTRPHL;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00528144

Pattern: motif3.motif

Significance: 0.034499699999999994

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.014387700000000002

Pattern: motif2.motif

Significance: 0.0387735

NIH3T3;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00428495

Pattern: motif5.motif

Significance: 0.00041710900000000003

3T3-L1;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.019646200000000003

Pattern: motif9.motif

Significance: 0.015871

DC_BMD;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.00030826299999999997

/

Pattern: metacluster_1/pattern_9

Significance: 0.0385922

Pattern: motif11.motif

Significance: 0.0008961980000000001

MCRPHG;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00999219

Pattern: motif7.motif

Significance: 0.000556371

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.045410400000000004

Pattern: motif13.motif

Significance: 0.042935

Adrenal;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00974841

Pattern: motif7.motif

Significance: 0.00044356800000000003

Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00305676

Pattern: motif13.motif

Significance: 0.000703391

placenta;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0115658

Pattern: motif9.motif

Significance: 0.0183096

pMeg;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00491719

Pattern: motif3.motif

Significance: 0.000129245

MegP;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.00808089

Pattern: motif4.motif

Significance: 0.000147455

pCMP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00260042

Pattern: motif9.motif

Significance: 0.020597900000000002

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.000668086

Pattern: motif6.motif

Significance: 0.011303200000000001

pGMP;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00270683

Pattern: motif3.motif

Significance: 0.000132494

DC;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00966207

Pattern: motif5.motif

Significance: 0.00105737

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00228823

Pattern: motif5.motif

Significance: 0.00429896

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00781599

Pattern: motif3.motif

Significance: 0.000136815

LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.00569282

Pattern: motif3.motif

Significance: 0.000953915

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00169343

Pattern: motif6.motif

Significance: 0.000587579

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0376192

Pattern: motif15.motif

Significance: 0.0570817

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0058323

Pattern: motif4.motif

Significance: 0.000193185

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0066592

Pattern: motif6.motif

Significance: 0.00115069

/

Pattern: motif11.motif

Significance: 0.0500224

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00600737

Pattern: motif17.motif

Significance: 0.0397126

LVR;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00694571

Pattern: motif3.motif

Significance: 5.46836e-05

NTRPHL;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.022412400000000002

/

Pattern: metacluster_0/pattern_7

Significance: 0.057512

/

Pattern: metacluster_0/pattern_12

Significance: 0.0006127390000000001

Pattern: motif5.motif

Significance: 0.000681014

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_9

Significance: 0.000331435

Pattern: motif15.motif

Significance: 0.0046799

LVR;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00624409

Pattern: motif9.motif

Significance: 0.00128044

LNG;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00681023

/

Pattern: metacluster_0/pattern_6

Significance: 0.0316326

Pattern: motif2.motif

Significance: 7.1478e-05

LNG;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0042395

/

Pattern: metacluster_1/pattern_5

Significance: 0.0398467

Pattern: motif4.motif

Significance: 0.000368386

Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00385235

Pattern: motif10.motif

Significance: 0.00531212

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00838324

Pattern: motif2.motif

Significance: 0.000591669

Adipose;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.0372156

/

Pattern: metacluster_0/pattern_1

Significance: 0.032757

Pattern: motif1.motif

Significance: 0.00012561

CRBLM;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.058465699999999995

Pattern: motif10.motif

Significance: 0.035521199999999996

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00134075

Pattern: motif6.motif

Significance: 0.000267052

Muller;P12;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.00844255

Pattern: motif9.motif

Significance: 0.0310226

/

Pattern: motif15.motif

Significance: 0.0012085000000000002

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0471223

/

Pattern: metacluster_1/pattern_10

Significance: 0.0376348

Pattern: motif8.motif

Significance: 0.0442716

Unique Cell types only TF-MoDISco finds Cebpd: #44

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00170455

Absent
naiveCD8;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0315668

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_9

Significance: 0.0392664

Absent
LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0505913

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.053111

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0504352

Absent
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.00691471

Absent
MEL;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0109995

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.05543819999999999

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_20

Significance: 2.00794e-05

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.028162799999999998

/

Pattern: metacluster_0/pattern_17

Significance: 0.05902090000000001

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00242952

Absent
MN1;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.03320669999999999

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.05534069999999999

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.00146284

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 6.702470000000001e-05

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0546184

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.052917

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00519553

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.058379099999999996

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0468561

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00507637

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0571396

Absent
Heart;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0006571389999999999

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00126768

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0121291

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.0477023

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_9

Significance: 0.0484597

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.0449074

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.05964169999999999

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0248534

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0504218

Absent
3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_14

Significance: 0.00961779

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.04024369999999999

Absent
gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.047366399999999996

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.04193

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0363432

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0519711

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0440189

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0005446709999999999

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.00038102199999999996

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0336296

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0379575

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.03773630000000001

Absent
Unique Cell types only Homer finds Cebpd: #3

Cell typeModiscoHomer
restingB;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0587057

ILC1_AbxGRMFree;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.05542419999999999

aB_LPS+IL21;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0557476