In [1]:
# Parameters
data_name = "Rxrg"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:33:15,485 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Rxrg: Motif: M02400_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Rxrg: #16

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.00935831

/

Pattern: metacluster_0/pattern_24

Significance: 0.0326528

Pattern: motif11.motif

Significance: 0.0484768

/

Pattern: motif17.motif

Significance: 0.055499900000000005

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0173932

Pattern: motif13.motif

Significance: 0.053350699999999994

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00886911

Pattern: motif8.motif

Significance: 0.0582553

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.019952

/

Pattern: metacluster_0/pattern_15

Significance: 0.0182479

Pattern: motif9.motif

Significance: 0.0333923

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 9.88993e-05

Pattern: motif12.motif

Significance: 0.00420516

ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 6.14933e-07

Pattern: motif14.motif

Significance: 0.00838183

Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.00688696

Pattern: motif7.motif

Significance: 0.045222000000000005

ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0245152

Pattern: motif7.motif

Significance: 0.0474965

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.016880799999999998

Pattern: motif14.motif

Significance: 0.0534936

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.00020229400000000003

Pattern: motif14.motif

Significance: 0.00434422

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.000581089

Pattern: motif32.motif

Significance: 0.000680363

ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.00257074

Pattern: motif22.motif

Significance: 0.000334837

Adrenal;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.000326647

/

Pattern: metacluster_1/pattern_15

Significance: 0.000379226

Pattern: motif2.motif

Significance: 2.8481e-05

/

Pattern: motif6.motif

Significance: 0.059524900000000006

ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00485879

Pattern: motif18.motif

Significance: 0.002876

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.040253

/

Pattern: metacluster_0/pattern_16

Significance: 0.0140502

/

Pattern: metacluster_0/pattern_18

Significance: 0.029457499999999998

Pattern: motif15.motif

Significance: 0.03524

wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.018619999999999998

Pattern: motif9.motif

Significance: 0.043267599999999996

/

Pattern: motif21.motif

Significance: 0.0591933

Unique Cell types only TF-MoDISco finds Rxrg: #51

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0392417

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_19

Significance: 0.024785599999999998

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.0310469

/

Pattern: metacluster_0/pattern_23

Significance: 0.012780799999999998

Absent
GC_B;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.0183123

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_18

Significance: 1.1830599999999998e-09

Absent
aB_LPS;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.041020999999999995

Absent
Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0598116

Absent
MEF.GATA-1-ER;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0174278

Absent
MEL;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.020951499999999998

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_22

Significance: 0.019706

Absent
ROD_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0318125

Absent
3T3-L1;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.017271099999999998

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.049762

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.039375400000000005

/

Pattern: metacluster_0/pattern_17

Significance: 0.0204259

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0253363

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.05198969999999999

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.026435200000000002

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.050933099999999995

/

Pattern: metacluster_0/pattern_21

Significance: 0.054665099999999994

/

Pattern: metacluster_0/pattern_24

Significance: 0.0335667

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.0273881

/

Pattern: metacluster_0/pattern_21

Significance: 0.0216072

/

Pattern: metacluster_0/pattern_22

Significance: 0.0231012

/

Pattern: metacluster_0/pattern_24

Significance: 0.039072699999999995

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.0351704

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0272661

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0270988

Absent
DP;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.0224634

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.021939900000000002

Absent
wES;GRM;E16.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.039217400000000006

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.05380309999999999

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.031766300000000004

Absent
testis;A;CL

Pattern: metacluster_0/pattern_14

Significance: 0.0538275

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.046655199999999994

Absent
STMCH;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0574215

Absent
MegEP;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.038020599999999995

Absent
pErythroblast;A;En

Pattern: metacluster_1/pattern_12

Significance: 0.0481398

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0114652

Absent
ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 6.12554e-05

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_17

Significance: 8.45715e-08

Absent
416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 9.61153e-05

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 2.08261e-08

/

Pattern: metacluster_1/pattern_19

Significance: 0.0370842

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_11

Significance: 0.032986400000000006

/

Pattern: metacluster_1/pattern_15

Significance: 0.0404143

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.000426041

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0107492

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.00284265

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0198443

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.030810300000000002

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_20

Significance: 0.051519100000000005

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0409608

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0421401

Absent
ILC3_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0275601

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0230105

Absent
EP;c-kit+CD71+Ter119+;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0326243

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.031844700000000004

/

Pattern: metacluster_1/pattern_20

Significance: 5.7855900000000005e-09

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0115326

Absent
Unique Cell types only Homer finds Rxrg: #8

Cell typeModiscoHomer
MPP;A;CLAbsent

Pattern: motif7.motif

Significance: 0.057984

NTRPHL;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.058932000000000005

LNG;8wks;D;EnAbsent

Pattern: motif8.motif

Significance: 0.0396755

LNG;P0;D;EnAbsent

Pattern: motif8.motif

Significance: 0.0514247

DC_BMD;A;CLAbsent

Pattern: motif13.motif

Significance: 0.0413565

apThEff;CD4+;8wks;D;En.Absent

Pattern: motif19.motif

Significance: 0.0586366

NK;IL2+IL12+;A;CLAbsent

Pattern: motif9.motif

Significance: 0.0483133

ES;ZhBTc4;untreated;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.000772377