In [1]:
# Parameters
data_name = "Stat4"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:40:10,201 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Stat4: Motif: M08174_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Stat4: #9

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.017274099999999997

Pattern: motif2.motif

Significance: 0.055097

CD4+CD8+TCR+CD69+CD24+;MHC2defM;A;C

Pattern: metacluster_1/pattern_0

Significance: 0.0204018

Pattern: motif2.motif

Significance: 0.0435726

CD4+CD8+TCR+CD69-CD24-;MHC2defM;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.047655

Pattern: motif2.motif

Significance: 0.0473332

ILC3;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.058919900000000004

Pattern: motif2.motif

Significance: 0.0410841

DP3a;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.024036099999999998

Pattern: motif2.motif

Significance: 0.0299041

NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.00892817

Pattern: motif2.motif

Significance: 0.0515709

TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0383115

Pattern: motif2.motif

Significance: 0.0382579

Teff;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00886224

Pattern: motif2.motif

Significance: 0.0318289

T_MLD;TCR_SV40-I_CD8+;D21;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.015125799999999998

Pattern: motif2.motif

Significance: 0.057688300000000005

Unique Cell types only TF-MoDISco finds Stat4: #63

Cell typeModiscoHomer
matureB;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.0437953

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_20

Significance: 0.0262289

Absent
BSPHL;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00729587

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0289007

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0508471

Absent
aNonTfh_mut;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.058782799999999996

Absent
naiveT;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.050393400000000005

Absent
naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0366431

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0241583

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.015402899999999999

Absent
CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.050425199999999996

Absent
CD4+CD8intTCR+CD69+CD24+;MHC2defM;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.028903199999999997

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0551677

/

Pattern: metacluster_1/pattern_14

Significance: 0.0508466

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0159183

Absent
DP;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.035203899999999996

/

Pattern: metacluster_1/pattern_17

Significance: 0.05495830000000001

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0236425

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0373015

Absent
Heart;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.018543599999999997

Absent
Adipose;A;CL

Pattern: metacluster_1/pattern_1

Significance: 0.0235871

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0517597

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0564643

Absent
NK;IL2+IL12+;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.015743700000000003

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.017861000000000002

Absent
ILC1;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0203426

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0375035

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_22

Significance: 0.044368300000000006

Absent
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0236115

Absent
ILC1;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0113845

/

Pattern: metacluster_1/pattern_19

Significance: 0.055912300000000005

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0560784

Absent
ILC1_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0446723

Absent
ILC3_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00751688

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.0174333

Absent
T_LCMV;CD8+;D8;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0139548

Absent
T_LCMV;CD8+;D33;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0402973

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0197984

Absent
TExh_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.017229400000000002

Absent
TSLEC_SPLND;CD8+A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0162674

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.0154463

/

Pattern: metacluster_0/pattern_17

Significance: 0.058673199999999995

Absent
Teff;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.022228499999999998

Absent
cntrl_memT;TCR_SV40-I_CD8+;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0148659

Absent
T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0186593

Absent
T_MLD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00927477

/

Pattern: metacluster_1/pattern_19

Significance: 0.054141800000000004

Absent
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0202011

Absent
T_MLD;TCR_SV40-I_CD8+;D60;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.0170424

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.0223072

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0220198

Absent
memT_tmrD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0135201

/

Pattern: metacluster_1/pattern_17

Significance: 0.0580134

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.011547499999999999

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.033474800000000006

Absent
ROD_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0571293

Absent
ROD_PHT_RCPTR_RTN;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.050052

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.048925199999999995

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0322322

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_26

Significance: 0.050376300000000006

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.050950300000000004

Absent
NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.040038

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0562398

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0422847

Absent
naiveT_SPLND;CD4+;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.025036000000000003

Absent
apCD4Eff;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0178061

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.05489730000000001

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.013527899999999999

Absent
apTreg;8wk;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0201183

Absent
Unique Cell types only Homer finds Stat4: #7

Cell typeModiscoHomer
LNG;8wks;D;EnAbsent

Pattern: motif15.motif

Significance: 0.056963599999999996

ES;v6.5;A;GEOAbsent

Pattern: motif20.motif

Significance: 0.0416286

ILC2+IL33+IL25;A;GEOAbsent

Pattern: motif2.motif

Significance: 0.0551371

T_SPLND_blstCLTRD;CD4+;D;GEOAbsent

Pattern: motif1.motif

Significance: 0.056862

EP;c-kit+CD71+Ter119+;D;EnAbsent

Pattern: motif4.motif

Significance: 0.040168300000000004

MN1;D;EnAbsent

Pattern: motif5.motif

Significance: 0.0274616

EPP;A;EnAbsent

Pattern: motif3.motif

Significance: 0.045145199999999996