In [1]:
# Parameters
data_name = "Sox3"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:35:45,948 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Sox3: Motif: M00827_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Sox3: #23

Cell typeModiscoHomer
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.000232988

Pattern: motif10.motif

Significance: 0.0226489

ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00674688

Pattern: motif9.motif

Significance: 0.00569875

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.000167283

/

Pattern: metacluster_0/pattern_17

Significance: 0.054755899999999996

Pattern: motif3.motif

Significance: 0.000164782

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.00013167299999999998

Pattern: motif2.motif

Significance: 6.63026e-05

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.00011450200000000001

Pattern: motif3.motif

Significance: 0.00010964899999999999

npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 9.8204e-05

Pattern: motif8.motif

Significance: 0.00289046

wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00011447200000000001

Pattern: motif3.motif

Significance: 0.000339289

wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.000169967

Pattern: motif3.motif

Significance: 0.00399169

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 6.0011400000000006e-05

/

Pattern: metacluster_0/pattern_17

Significance: 0.053443399999999995

Pattern: motif4.motif

Significance: 3.1062199999999995e-05

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00011486200000000001

Pattern: motif6.motif

Significance: 0.022268299999999998

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00022302200000000002

Pattern: motif3.motif

Significance: 1.60181e-05

wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00142997

Pattern: motif8.motif

Significance: 0.00291754

npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.000225943

Pattern: motif4.motif

Significance: 0.00302433

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00130416

Pattern: motif14.motif

Significance: 0.00821848

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 7.29288e-05

Pattern: motif4.motif

Significance: 0.00961532

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 1.94952e-05

Pattern: motif7.motif

Significance: 0.0189149

ES;E14;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.030695799999999995

Pattern: motif7.motif

Significance: 0.0347236

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00141559

Pattern: motif20.motif

Significance: 0.041231300000000005

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00724777

Pattern: motif7.motif

Significance: 0.00250399

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.000129938

Pattern: motif13.motif

Significance: 0.00501142

Muller;P12;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00145457

Pattern: motif8.motif

Significance: 0.043644800000000004

wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.000286264

Pattern: motif7.motif

Significance: 0.00211327

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.000166007

Pattern: motif6.motif

Significance: 0.00329083

Unique Cell types only TF-MoDISco finds Sox3: #51

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.010078799999999999

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.00340214

/

Pattern: metacluster_0/pattern_16

Significance: 0.0546862

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00581635

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.00302883

/

Pattern: metacluster_0/pattern_15

Significance: 0.059132699999999996

/

Pattern: metacluster_0/pattern_22

Significance: 0.0581322

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.00292146

Absent
wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00552292

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0009548730000000001

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0502382

/

Pattern: metacluster_0/pattern_22

Significance: 0.058075

/

Pattern: metacluster_0/pattern_23

Significance: 0.0282242

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.00682042

/

Pattern: metacluster_0/pattern_19

Significance: 0.0429655

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.000828603

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.000950056

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00329485

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.019965

Absent
npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.00569736

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0456271

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0227724

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_10

Significance: 0.001263

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.024941400000000002

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.000395534

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.055171300000000006

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00680862

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.00732306

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.00258954

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00794456

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.028326

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00795982

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0350765

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.011974

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00142796

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0465039

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0009544460000000001

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.052834000000000006

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0368573

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0152451

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 3.91971e-05

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0362346

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.015419899999999999

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00186531

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.024758099999999998

/

Pattern: metacluster_0/pattern_17

Significance: 0.043595

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_19

Significance: 0.00208312

Absent
RTN;D1;D;En

Pattern: metacluster_0/pattern_5

Significance: 3.48899e-05

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.000562056

/

Pattern: metacluster_0/pattern_19

Significance: 0.053468100000000005

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00186989

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00107324

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00348597

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00015593899999999999

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00187341

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.0018777999999999998

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00361468

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00299278

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.00610468

Absent
No Cell types only Homer finds Sox3