In [1]:
# Parameters
data_name = "Sox17"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:35:30,430 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Sox17: Motif: M08040_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Sox17: #22

Cell typeModiscoHomer
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00361017

Pattern: motif9.motif

Significance: 0.00561556

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.000167283

Pattern: motif3.motif

Significance: 7.37019e-05

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.000230018

Pattern: motif2.motif

Significance: 2.25619e-05

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.000531269

Pattern: motif3.motif

Significance: 9.677299999999999e-05

npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.000351376

Pattern: motif8.motif

Significance: 0.0123541

wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 1.73077e-05

Pattern: motif3.motif

Significance: 2.8580900000000003e-05

wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00021344799999999998

Pattern: motif3.motif

Significance: 0.00253983

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.000307795

Pattern: motif4.motif

Significance: 0.000123426

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00028491

Pattern: motif6.motif

Significance: 0.00321068

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00021376299999999998

Pattern: motif3.motif

Significance: 2.49567e-06

wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0014459000000000002

Pattern: motif8.motif

Significance: 0.00733556

npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.000867429

Pattern: motif4.motif

Significance: 8.53727e-05

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00103739

Pattern: motif14.motif

Significance: 0.0130589

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 9.02452e-05

Pattern: motif4.motif

Significance: 0.000351543

ES;E14;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00306969

Pattern: motif7.motif

Significance: 0.0225086

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0008700810000000001

Pattern: motif16.motif

Significance: 0.041261400000000004

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.000398629

Pattern: motif20.motif

Significance: 0.0037567

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0113705

Pattern: motif7.motif

Significance: 0.00333486

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.00010049399999999999

Pattern: motif13.motif

Significance: 0.0280825

Muller;P12;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.000433987

Pattern: motif8.motif

Significance: 0.0471529

wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.000842318

Pattern: motif7.motif

Significance: 0.000451375

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00123528

Pattern: motif6.motif

Significance: 0.00350816

Unique Cell types only TF-MoDISco finds Sox17: #49

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.0385773

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.00057318

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0510168

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.00302883

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.00872091

Absent
wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00552292

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.00069893

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00078921

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_23

Significance: 0.0282242

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0500937

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0007031510000000001

Absent
NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00022440400000000002

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00316299

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00419216

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00271224

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00696248

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00516995

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_10

Significance: 0.001335

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0119141

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00858338

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.00836708

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.0044298

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.032793699999999995

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00973157

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00795982

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00799584

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.01757

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00276927

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0444414

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0166558

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0009710869999999999

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.000796484

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.000759563

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00422423

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.008460700000000002

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00155503

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.00181025

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_19

Significance: 0.0555572

Absent
RTN;D1;D;En

Pattern: metacluster_0/pattern_5

Significance: 2.89875e-05

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00219166

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00186989

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00126645

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.000594056

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00015593899999999999

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00108891

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00106748

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0165819

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0129805

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.0428499

Absent
No Cell types only Homer finds Sox17