In [1]:
# Parameters
data_name = "Atf4"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 10:58:11,633 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Atf4: Motif: M02865_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Atf4: #39

Cell typeModiscoHomer
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.05069

Pattern: motif5.motif

Significance: 0.055129899999999996

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0033106000000000003

Pattern: motif6.motif

Significance: 0.000403475

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.047364699999999996

/

Pattern: metacluster_1/pattern_7

Significance: 0.013032299999999998

Pattern: motif11.motif

Significance: 0.0572279

AML;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0169911

/

Pattern: metacluster_1/pattern_11

Significance: 0.058986800000000006

Pattern: motif3.motif

Significance: 0.0196232

DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00480388

/

Pattern: metacluster_1/pattern_7

Significance: 0.0526399

Pattern: motif5.motif

Significance: 0.043023

BSPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00478372

Pattern: motif6.motif

Significance: 0.029245599999999997

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.00891677

Pattern: motif9.motif

Significance: 0.0217183

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0188762

/

Pattern: metacluster_1/pattern_6

Significance: 0.03529469999999999

Pattern: motif6.motif

Significance: 0.057389499999999996

NTRPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0525279

/

Pattern: metacluster_1/pattern_4

Significance: 0.00616959

Pattern: motif3.motif

Significance: 0.059038400000000005

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00662452

/

Pattern: metacluster_1/pattern_6

Significance: 0.048977099999999996

Pattern: motif2.motif

Significance: 0.00055455

/

Pattern: motif6.motif

Significance: 0.054693200000000004

NIH3T3;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00317009

Pattern: motif5.motif

Significance: 0.0530938

MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0529155

/

Pattern: metacluster_0/pattern_16

Significance: 0.028162799999999998

/

Pattern: metacluster_0/pattern_17

Significance: 0.00258668

Pattern: motif7.motif

Significance: 0.05405359999999999

3T3-L1;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.054037699999999994

/

Pattern: metacluster_1/pattern_9

Significance: 5.6201899999999995e-05

Pattern: motif9.motif

Significance: 0.00298238

MCRPHG;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0230418

Pattern: motif7.motif

Significance: 0.027051599999999995

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0414381

Pattern: motif13.motif

Significance: 0.058155899999999996

Adrenal;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00974841

Pattern: motif7.motif

Significance: 0.044613599999999996

placenta;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0204512

Pattern: motif9.motif

Significance: 0.033801599999999994

pMeg;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00553869

Pattern: motif3.motif

Significance: 0.0189835

MegP;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.00386808

Pattern: motif4.motif

Significance: 0.029351099999999998

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.046883600000000004

Pattern: motif6.motif

Significance: 0.0498324

pGMP;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00467485

Pattern: motif3.motif

Significance: 0.0216881

DC;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00364727

/

Pattern: metacluster_1/pattern_7

Significance: 0.0584634

Pattern: motif5.motif

Significance: 0.050354699999999995

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00888805

Pattern: motif5.motif

Significance: 0.028654400000000003

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.00879772

Pattern: motif3.motif

Significance: 0.0292207

LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.0111308

Pattern: motif3.motif

Significance: 0.0518668

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00346472

Pattern: motif6.motif

Significance: 0.0596342

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00526181

/

Pattern: metacluster_1/pattern_7

Significance: 0.047361

Pattern: motif4.motif

Significance: 0.058305899999999994

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00557229

/

Pattern: metacluster_1/pattern_10

Significance: 0.0449202

Pattern: motif6.motif

Significance: 0.059344900000000006

/

Pattern: motif11.motif

Significance: 0.0319702

/

Pattern: motif14.motif

Significance: 0.052006399999999994

3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.05777569999999999

/

Pattern: metacluster_1/pattern_9

Significance: 0.000341159

Pattern: motif17.motif

Significance: 0.00036783199999999996

LVR;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00631426

Pattern: motif3.motif

Significance: 0.0422733

NTRPHL;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.010059700000000001

/

Pattern: metacluster_0/pattern_12

Significance: 0.036664999999999996

Pattern: motif5.motif

Significance: 0.05499580000000001

LVR;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0109089

Pattern: motif9.motif

Significance: 0.0468017

LNG;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00878896

/

Pattern: metacluster_0/pattern_6

Significance: 0.0509633

Pattern: motif2.motif

Significance: 0.0272846

LNG;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00507467

Pattern: motif4.motif

Significance: 0.0522255

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0108314

Pattern: motif2.motif

Significance: 0.0564624

Adipose;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.058603800000000004

/

Pattern: metacluster_0/pattern_1

Significance: 0.013934700000000001

Pattern: motif1.motif

Significance: 0.0170097

CRBLM;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.044493

Pattern: motif10.motif

Significance: 0.021243900000000003

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00748973

Pattern: motif6.motif

Significance: 0.0216956

Muller;P12;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.00487533

/

Pattern: metacluster_1/pattern_11

Significance: 0.056205099999999994

Pattern: motif9.motif

Significance: 0.0437883

/

Pattern: motif15.motif

Significance: 0.0499272

Unique Cell types only TF-MoDISco finds Atf4: #52

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00621977

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_9

Significance: 0.0531019

Absent
LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0333294

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0514173

Absent
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.0580356

/

Pattern: metacluster_0/pattern_12

Significance: 0.000868223

Absent
MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.00613499

Absent
CH12.LX;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.029481599999999997

Absent
AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.05445030000000001

Absent
MEL;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0268976

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.0174051

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00718684

Absent
MN1;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.05255309999999999

/

Pattern: metacluster_1/pattern_15

Significance: 0.000843462

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.05994730000000001

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.028668700000000002

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.024882400000000002

/

Pattern: metacluster_0/pattern_15

Significance: 0.058325800000000004

Absent
NPC;F129;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0546184

Absent
DC_BMD;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.04783540000000001

/

Pattern: metacluster_1/pattern_9

Significance: 0.0479259

Absent
NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.056170000000000005

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0433556

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.056134

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00028571900000000003

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.016412700000000002

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.027034199999999998

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0135915

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.05410269999999999

Absent
Heart;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.028540899999999998

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.0426441

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0530302

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0543947

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00359984

/

Pattern: metacluster_0/pattern_8

Significance: 0.047531699999999996

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.05544059999999999

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.059949199999999994

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.037266900000000006

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.059602999999999996

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0479684

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0504218

Absent
3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_14

Significance: 0.0154423

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0574485

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_20

Significance: 4.82961e-05

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0323589

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0542518

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_9

Significance: 0.014094399999999998

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0230215

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.05395369999999999

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00280253

/

Pattern: metacluster_1/pattern_13

Significance: 0.0482407

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.023212599999999996

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.05846669999999999

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.05949490000000001

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_13

Significance: 0.0477347

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.03773630000000001

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.054172500000000005

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0541928

/

Pattern: metacluster_1/pattern_10

Significance: 0.0426024

Absent
Unique Cell types only Homer finds Atf4: #4

Cell typeModiscoHomer
restingB;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0587057

ILC1_AbxGRMFree;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.05542419999999999

ePyramidal_NRN;A;GEOAbsent

Pattern: motif7.motif

Significance: 0.0458534

aB_LPS+IL21;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0530492